Motif ID: HSFY2

Z-value: 0.664


Transcription factors associated with HSFY2:

Gene SymbolEntrez IDGene Name
HSFY2 ENSG00000169953.11 HSFY2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HSFY2hg19_v2_chrY_-_20935572_209356210.049.2e-01Click!


Activity profile for motif HSFY2.

activity profile for motif HSFY2


Sorted Z-values histogram for motif HSFY2

Sorted Z-values for motif HSFY2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSFY2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_202483867 0.824 ENST00000439802.1
ENST00000286195.3
ENST00000439140.1
ENST00000450242.1
ALS2CR11



amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11



chr16_-_31214051 0.800 ENST00000350605.4
PYCARD
PYD and CARD domain containing
chr10_+_5005598 0.721 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr11_+_34654011 0.570 ENST00000531794.1
EHF
ets homologous factor
chr10_-_5046042 0.489 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr9_+_470288 0.464 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr9_+_95820966 0.453 ENST00000375472.3
ENST00000465709.1
SUSD3

sushi domain containing 3

chr5_+_76114758 0.420 ENST00000514165.1
ENST00000296677.4
F2RL1

coagulation factor II (thrombin) receptor-like 1

chr7_-_95025661 0.399 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3


paraoxonase 1
paraoxonase 3


chr4_-_89080003 0.392 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr6_+_116782527 0.356 ENST00000368606.3
ENST00000368605.1
FAM26F

family with sequence similarity 26, member F

chr4_-_36245561 0.350 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_35840198 0.346 ENST00000412856.1
ENST00000437235.3
ENST00000424194.1
AC007551.3


AC007551.3


chr12_-_71533055 0.343 ENST00000552128.1
TSPAN8
tetraspanin 8
chr2_+_149974684 0.341 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr6_-_73935163 0.337 ENST00000370388.3
KHDC1L
KH homology domain containing 1-like
chr2_+_233497931 0.322 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr4_-_89079817 0.306 ENST00000505480.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr20_+_10199468 0.298 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr1_-_109203997 0.297 ENST00000370032.5
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr8_-_120259055 0.285 ENST00000522828.1
ENST00000523307.1
ENST00000524129.1
ENST00000521048.1
ENST00000522187.1
RP11-4K16.2




RP11-4K16.2




chr10_-_56561022 0.277 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
PCDH15













protocadherin-related 15













chr8_-_17579726 0.270 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr6_+_125524785 0.264 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr7_-_124405681 0.263 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr11_-_110583451 0.256 ENST00000260283.4
ENST00000528829.1
ARHGAP20

Rho GTPase activating protein 20

chr1_-_57045228 0.255 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr10_+_91061712 0.241 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr8_+_120428546 0.239 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr4_-_75695366 0.239 ENST00000512743.1
BTC
betacellulin
chr13_-_24471641 0.238 ENST00000382145.1
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr2_+_65216462 0.235 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr4_+_187148556 0.228 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr14_+_39944025 0.228 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr11_-_110583912 0.222 ENST00000533353.1
ENST00000527598.1
ARHGAP20

Rho GTPase activating protein 20

chr12_+_96337061 0.218 ENST00000266736.2
AMDHD1
amidohydrolase domain containing 1
chr5_+_32788945 0.216 ENST00000326958.1
AC026703.1
AC026703.1
chr17_+_18625336 0.212 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L




tripartite motif containing 16-like




chr2_+_162949939 0.202 ENST00000432251.1
AC008063.3
AC008063.3
chr6_-_26285737 0.195 ENST00000377727.1
ENST00000289352.1
HIST1H4H

histone cluster 1, H4h

chr4_-_89080362 0.194 ENST00000503830.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr8_-_19459993 0.189 ENST00000454498.2
ENST00000520003.1
CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr3_+_173116225 0.188 ENST00000457714.1
NLGN1
neuroligin 1
chr3_-_171489085 0.186 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr2_+_207139367 0.184 ENST00000374423.3
ZDBF2
zinc finger, DBF-type containing 2
chr6_-_26033796 0.180 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr3_-_170626418 0.177 ENST00000474096.1
ENST00000295822.2
EIF5A2

eukaryotic translation initiation factor 5A2

chr20_+_19738300 0.171 ENST00000432334.1
RP1-122P22.2
RP1-122P22.2
chr13_+_20268547 0.170 ENST00000601204.1
AL354808.2
AL354808.2
chr10_-_5227096 0.169 ENST00000488756.1
ENST00000334314.3
AKR1CL1

aldo-keto reductase family 1, member C-like 1

chr19_+_50194360 0.168 ENST00000323446.5
ENST00000392518.4
ENST00000598396.1
ENST00000598293.1
ENST00000354199.5
ENST00000405931.2
ENST00000602019.1
CPT1C






carnitine palmitoyltransferase 1C






chr7_+_142498725 0.167 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr20_+_10199566 0.164 ENST00000430336.1
SNAP25
synaptosomal-associated protein, 25kDa
chrX_-_48693955 0.158 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr6_+_46661575 0.151 ENST00000450697.1
TDRD6
tudor domain containing 6
chr22_-_36013368 0.148 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr9_-_39239171 0.147 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr8_+_22224811 0.146 ENST00000381237.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr4_+_52917451 0.145 ENST00000295213.4
ENST00000419395.2
SPATA18

spermatogenesis associated 18

chr4_-_105416039 0.145 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr6_+_8652370 0.144 ENST00000503668.1
HULC
hepatocellular carcinoma up-regulated long non-coding RNA
chr14_+_85996471 0.144 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_+_196788887 0.142 ENST00000367421.3
ENST00000320493.5
ENST00000367424.4
CFHR2
CFHR1

complement factor H-related 2
complement factor H-related 1

chr19_+_12305895 0.141 ENST00000451691.2
CTD-2666L21.1
CTD-2666L21.1
chr11_+_5646213 0.140 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr2_-_152589670 0.139 ENST00000604864.1
ENST00000603639.1
NEB

nebulin

chr12_-_10562356 0.138 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr2_+_201170770 0.137 ENST00000409988.3
ENST00000409385.1
SPATS2L

spermatogenesis associated, serine-rich 2-like

chr12_-_11139511 0.136 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr2_+_201170596 0.136 ENST00000439084.1
ENST00000409718.1
SPATS2L

spermatogenesis associated, serine-rich 2-like

chr4_-_168155169 0.135 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr1_+_245027971 0.134 ENST00000610145.1
RP11-11N7.4
RP11-11N7.4
chrX_-_15511438 0.130 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr18_+_32402321 0.125 ENST00000587723.1
DTNA
dystrobrevin, alpha
chr5_-_156569850 0.124 ENST00000524219.1
HAVCR2
hepatitis A virus cellular receptor 2
chr2_+_201170703 0.124 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr3_-_25915189 0.123 ENST00000451284.1
LINC00692
long intergenic non-protein coding RNA 692
chr12_-_111142729 0.123 ENST00000546713.1
HVCN1
hydrogen voltage-gated channel 1
chr17_-_30470154 0.122 ENST00000398832.2
AC090616.2
Uncharacterized protein
chr3_-_187455680 0.121 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr6_-_47277634 0.121 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_64431146 0.120 ENST00000569824.1
ENST00000485770.1
PRICKLE2
RP11-14D22.2
prickle homolog 2 (Drosophila)
RP11-14D22.2
chr4_+_150999418 0.120 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr4_-_36246060 0.119 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_61523622 0.118 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
CYB561




cytochrome b561




chr6_+_163148161 0.117 ENST00000337019.3
ENST00000366889.2
PACRG

PARK2 co-regulated

chr14_+_85996507 0.117 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr3_+_122044084 0.116 ENST00000264474.3
ENST00000479204.1
CSTA

cystatin A (stefin A)

chr4_-_114438763 0.116 ENST00000509594.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr6_-_39902185 0.115 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
MOCS1


molybdenum cofactor synthesis 1


chr1_+_183605222 0.112 ENST00000536277.1
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr12_+_66218212 0.110 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2



high mobility group AT-hook 2



chr1_+_10490779 0.110 ENST00000477755.1
APITD1
apoptosis-inducing, TAF9-like domain 1
chr2_+_28853443 0.109 ENST00000436775.1
PLB1
phospholipase B1
chr11_-_104916034 0.109 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16


caspase recruitment domain family, member 16


chr9_+_131684027 0.109 ENST00000426694.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr19_-_43690674 0.108 ENST00000342951.6
ENST00000366175.3
PSG5

pregnancy specific beta-1-glycoprotein 5

chr4_+_110834033 0.108 ENST00000509793.1
ENST00000265171.5
EGF

epidermal growth factor

chr1_-_11159887 0.108 ENST00000544779.1
ENST00000304457.7
ENST00000376936.4
EXOSC10


exosome component 10


chr15_+_69365272 0.108 ENST00000559914.1
ENST00000558369.1
LINC00277

long intergenic non-protein coding RNA 277

chr3_+_183903811 0.108 ENST00000429586.2
ENST00000292808.5
ABCF3

ATP-binding cassette, sub-family F (GCN20), member 3

chr6_-_39902160 0.107 ENST00000340692.5
MOCS1
molybdenum cofactor synthesis 1
chr17_-_61523535 0.107 ENST00000584031.1
ENST00000392976.1
CYB561

cytochrome b561

chr1_-_10532531 0.106 ENST00000377036.2
ENST00000377038.3
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr10_-_36812323 0.106 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr8_+_38089198 0.105 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD2



DDHD domain containing 2



chr8_-_42065187 0.105 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT


plasminogen activator, tissue


chr1_+_183605200 0.105 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_-_40632605 0.105 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr8_-_63998590 0.104 ENST00000260116.4
TTPA
tocopherol (alpha) transfer protein
chr2_+_181988560 0.104 ENST00000424170.1
ENST00000435411.1
AC104820.2

AC104820.2

chrX_-_75005054 0.104 ENST00000373359.2
MAGEE2
melanoma antigen family E, 2
chr10_-_14574705 0.104 ENST00000489100.1
FAM107B
family with sequence similarity 107, member B
chr10_+_96522361 0.104 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr14_+_39734482 0.103 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5



CTAGE family, member 5



chr8_-_42065075 0.102 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT



plasminogen activator, tissue



chr4_+_81256871 0.101 ENST00000358105.3
ENST00000508675.1
C4orf22

chromosome 4 open reading frame 22

chr10_-_90611566 0.100 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr3_+_184053703 0.100 ENST00000450976.1
ENST00000418281.1
ENST00000340957.5
ENST00000433578.1
FAM131A



family with sequence similarity 131, member A



chr5_-_137071689 0.100 ENST00000505853.1
KLHL3
kelch-like family member 3
chr17_+_28705921 0.099 ENST00000225719.4
CPD
carboxypeptidase D
chr11_-_88796803 0.099 ENST00000418177.2
ENST00000455756.2
GRM5

glutamate receptor, metabotropic 5

chr1_+_74701062 0.098 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr2_+_201754050 0.098 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3L1




NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)




chr10_+_71812552 0.098 ENST00000373255.4
H2AFY2
H2A histone family, member Y2
chr9_+_125512019 0.097 ENST00000373684.1
ENST00000304720.2
OR1L6

olfactory receptor, family 1, subfamily L, member 6

chr22_-_36635225 0.096 ENST00000529194.1
APOL2
apolipoprotein L, 2
chr8_-_36636676 0.096 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1

RP11-962G15.1

chr1_-_10003372 0.095 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC


leucine zipper and CTNNBIP1 domain containing


chr3_-_186288097 0.095 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr8_+_69242957 0.095 ENST00000518698.1
ENST00000539993.1
C8orf34

chromosome 8 open reading frame 34

chr3_-_10149907 0.094 ENST00000450660.2
ENST00000524279.1
FANCD2OS

FANCD2 opposite strand

chr4_-_40632844 0.092 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr2_-_219151984 0.092 ENST00000444000.1
ENST00000418569.1
TMBIM1

transmembrane BAX inhibitor motif containing 1

chr12_-_48419165 0.091 ENST00000547602.1
RP1-228P16.5
Uncharacterized protein
chr1_+_62417957 0.090 ENST00000307297.7
ENST00000543708.1
INADL

InaD-like (Drosophila)

chr22_-_32341336 0.088 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr5_-_122372354 0.087 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr20_-_271304 0.087 ENST00000400269.3
ENST00000360321.2
C20orf96

chromosome 20 open reading frame 96

chr16_+_31724618 0.085 ENST00000530881.1
ENST00000529515.1
ZNF720

zinc finger protein 720

chr10_+_133918175 0.085 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3
chrX_-_153744434 0.083 ENST00000369643.1
ENST00000393572.1
FAM3A

family with sequence similarity 3, member A

chrX_-_55020511 0.082 ENST00000375006.3
ENST00000374992.2
PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

chr4_+_69313145 0.082 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chrX_+_48687283 0.082 ENST00000338270.1
ERAS
ES cell expressed Ras
chr6_+_30614779 0.081 ENST00000293604.6
ENST00000376473.5
C6orf136

chromosome 6 open reading frame 136

chr4_-_111563279 0.081 ENST00000511837.1
PITX2
paired-like homeodomain 2
chr1_+_24104869 0.081 ENST00000246151.4
PITHD1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr4_-_1166954 0.081 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
SPON2


spondin 2, extracellular matrix protein


chr14_-_23762777 0.080 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr13_-_33112823 0.079 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr10_+_71812577 0.079 ENST00000455786.1
H2AFY2
H2A histone family, member Y2
chr3_-_183967296 0.079 ENST00000455059.1
ENST00000445626.2
ALG3

ALG3, alpha-1,3- mannosyltransferase

chr3_-_129375556 0.079 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr2_-_122262593 0.078 ENST00000418989.1
CLASP1
cytoplasmic linker associated protein 1
chr3_-_186262166 0.078 ENST00000307944.5
CRYGS
crystallin, gamma S
chr1_-_6453426 0.077 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr8_+_17780483 0.077 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
PCM1



pericentriolar material 1



chr4_+_79472673 0.077 ENST00000264908.6
ANXA3
annexin A3
chr18_-_61329118 0.077 ENST00000332821.8
ENST00000283752.5
SERPINB3

serpin peptidase inhibitor, clade B (ovalbumin), member 3

chr9_+_116343192 0.077 ENST00000471324.2
RGS3
regulator of G-protein signaling 3
chr19_+_7828035 0.077 ENST00000327325.5
ENST00000394122.2
ENST00000248228.4
ENST00000334806.5
ENST00000359059.5
ENST00000357361.2
ENST00000596363.1
ENST00000595751.1
ENST00000596707.1
ENST00000597522.1
ENST00000595496.1
CLEC4M










C-type lectin domain family 4, member M










chr1_-_92371839 0.077 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr8_+_1993152 0.076 ENST00000262113.4
MYOM2
myomesin 2
chr8_+_17780346 0.076 ENST00000325083.8
PCM1
pericentriolar material 1
chr4_+_152330390 0.076 ENST00000503146.1
ENST00000435205.1
FAM160A1

family with sequence similarity 160, member A1

chr20_-_3219828 0.075 ENST00000539553.2
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr12_+_75874580 0.075 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr6_-_41715128 0.075 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC


progastricsin (pepsinogen C)


chr13_+_114462193 0.074 ENST00000375353.3
TMEM255B
transmembrane protein 255B
chr2_+_196521458 0.074 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr21_-_35884573 0.074 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr15_-_45694380 0.073 ENST00000561148.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr1_-_6453399 0.073 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr5_+_111496554 0.073 ENST00000442823.2
EPB41L4A-AS1
EPB41L4A antisense RNA 1
chr16_-_21663919 0.073 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr2_+_196521903 0.072 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_+_201754135 0.072 ENST00000409357.1
ENST00000409129.2
NIF3L1

NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)

chr6_-_169582835 0.072 ENST00000564830.1
RP11-417E7.2
RP11-417E7.2
chr3_+_69985792 0.072 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr8_+_20054878 0.071 ENST00000276390.2
ENST00000519667.1
ATP6V1B2

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

chr19_-_52674896 0.071 ENST00000322146.8
ENST00000597065.1
ZNF836

zinc finger protein 836

chr19_+_50706866 0.071 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14




myosin, heavy chain 14, non-muscle




chr1_-_84326618 0.071 ENST00000417565.1
RP11-475O6.1
RP11-475O6.1
chr2_+_69002052 0.069 ENST00000497079.1
ARHGAP25
Rho GTPase activating protein 25
chr18_+_57567180 0.069 ENST00000316660.6
ENST00000269518.9
PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

chr11_+_12132117 0.069 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr10_-_75682535 0.069 ENST00000409178.1
C10orf55
chromosome 10 open reading frame 55
chr11_+_32851487 0.068 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr12_+_14956506 0.068 ENST00000330828.2
C12orf60
chromosome 12 open reading frame 60
chr19_+_57874835 0.068 ENST00000282282.3
ENST00000543226.1
ENST00000596755.1
ENST00000597658.1
ZNF547
TRAPPC2P1

AC003002.4
zinc finger protein 547
trafficking protein particle complex 2 pseudogene 1

Uncharacterized protein
chr6_+_42531798 0.068 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2


ubiquitin protein ligase E3 component n-recognin 2


chr11_-_66725837 0.067 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr7_-_87342564 0.067 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chrX_+_49028265 0.067 ENST00000376322.3
ENST00000376327.5
PLP2

proteolipid protein 2 (colonic epithelium-enriched)

chr2_+_196521845 0.066 ENST00000359634.5
ENST00000412905.1
SLC39A10

solute carrier family 39 (zinc transporter), member 10

chr4_-_798689 0.066 ENST00000504062.1
CPLX1
complexin 1
chr1_+_234509186 0.066 ENST00000366615.4
COA6
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
chr19_-_14952689 0.065 ENST00000248058.1
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr2_+_192141611 0.064 ENST00000392316.1
MYO1B
myosin IB

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 1.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.4 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.5 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.4 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.9 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0098942 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746) cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0002856 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.3 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.0 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.0 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0006974 cellular response to DNA damage stimulus(GO:0006974)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0032090 Pyrin domain binding(GO:0032090)
0.2 1.2 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.4 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.2 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.0 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle