Motif ID: HOXD11_HOXA11

Z-value: 0.475

Transcription factors associated with HOXD11_HOXA11:

Gene SymbolEntrez IDGene Name
HOXA11 ENSG00000005073.5 HOXA11
HOXD11 ENSG00000128713.11 HOXD11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD11hg19_v2_chr2_+_176972000_176972025-0.245.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_71384257 0.754 ENST00000339336.4
AMTN
amelotin
chr4_+_71384300 0.736 ENST00000504451.1
AMTN
amelotin
chr12_+_54384370 0.732 ENST00000504315.1
HOXC6
homeobox C6
chr7_-_41742697 0.676 ENST00000242208.4
INHBA
inhibin, beta A
chr13_-_46742630 0.600 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_52056548 0.573 ENST00000545061.1
ENST00000355133.3
SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

chr3_+_164924716 0.568 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2

RP11-85M11.2

chr12_-_55378470 0.563 ENST00000524668.1
ENST00000533607.1
TESPA1

thymocyte expressed, positive selection associated 1

chrX_+_16668278 0.489 ENST00000380200.3
S100G
S100 calcium binding protein G
chr14_-_25479811 0.485 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr10_-_62332357 0.443 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_128293323 0.443 ENST00000389524.4
ENST00000428314.1
MYO7B

myosin VIIB

chr8_+_77318769 0.432 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr6_+_127898312 0.374 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr11_-_26588634 0.371 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chr2_-_68052694 0.354 ENST00000457448.1
AC010987.6
AC010987.6
chr7_+_128784712 0.332 ENST00000289407.4
TSPAN33
tetraspanin 33
chr19_+_41281060 0.326 ENST00000594436.1
ENST00000597784.1
MIA

melanoma inhibitory activity

chr6_+_78400375 0.323 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr3_-_165555200 0.316 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr20_-_56647116 0.314 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1

RP13-379L11.1

chr12_-_18243119 0.314 ENST00000538724.1
ENST00000229002.2
RERGL

RERG/RAS-like

chr12_-_62586543 0.313 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_-_26593677 0.313 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr11_-_26593779 0.312 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr20_-_7921090 0.307 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr3_+_111630451 0.306 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr8_-_16424871 0.302 ENST00000518026.1
MSR1
macrophage scavenger receptor 1
chr6_+_12958137 0.298 ENST00000457702.2
ENST00000379345.2
PHACTR1

phosphatase and actin regulator 1

chr3_+_151531810 0.293 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr19_+_41281282 0.292 ENST00000263369.3
MIA
melanoma inhibitory activity
chr11_-_26593649 0.275 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr4_+_120056939 0.270 ENST00000307128.5
MYOZ2
myozenin 2
chr5_+_167182003 0.251 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr12_+_9066472 0.242 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr12_-_71148357 0.229 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr18_-_52989217 0.226 ENST00000570287.2
TCF4
transcription factor 4
chr17_-_71258491 0.221 ENST00000397671.1
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr7_+_18329712 0.220 ENST00000433709.2
HDAC9
histone deacetylase 9
chr21_+_35736302 0.219 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr10_-_61899124 0.219 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr16_+_77822427 0.218 ENST00000302536.2
VAT1L
vesicle amine transport 1-like
chr21_+_17792672 0.212 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_+_41281416 0.210 ENST00000597140.1
MIA
melanoma inhibitory activity
chr10_+_102222798 0.207 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr6_+_13272904 0.206 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr22_-_32651326 0.205 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr2_-_74726710 0.205 ENST00000377566.4
LBX2
ladybird homeobox 2
chr8_+_104892639 0.203 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr1_+_244515930 0.202 ENST00000366537.1
ENST00000308105.4
C1orf100

chromosome 1 open reading frame 100

chr15_+_54901540 0.198 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr3_+_140981456 0.196 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr6_+_12717892 0.196 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr12_+_86268065 0.194 ENST00000551529.1
ENST00000256010.6
NTS

neurotensin

chr12_+_76653682 0.194 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr4_-_153601136 0.194 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr8_+_80209929 0.191 ENST00000519983.1
RP11-1114I9.1
RP11-1114I9.1
chrX_+_16188506 0.189 ENST00000329538.5
MAGEB17
melanoma antigen family B, 17
chr3_+_151531859 0.188 ENST00000488869.1
AADAC
arylacetamide deacetylase
chr13_-_46626820 0.187 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chrX_-_33229636 0.186 ENST00000357033.4
DMD
dystrophin
chr12_-_71148413 0.186 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR


protein tyrosine phosphatase, receptor type, R


chr10_-_62493223 0.186 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_181988620 0.183 ENST00000428474.1
ENST00000424655.1
AC104820.2

AC104820.2

chr6_-_119031228 0.183 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L


centrosomal protein 85kDa-like


chr10_-_61900762 0.183 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_230991747 0.182 ENST00000523410.1
C1orf198
chromosome 1 open reading frame 198
chr2_+_67624430 0.180 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chr3_-_156534754 0.175 ENST00000472943.1
ENST00000473352.1
LINC00886

long intergenic non-protein coding RNA 886

chr19_-_55677999 0.173 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr13_+_77522632 0.173 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr10_+_85933494 0.167 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr13_-_46626847 0.167 ENST00000242848.4
ENST00000282007.3
ZC3H13

zinc finger CCCH-type containing 13

chr17_-_38821373 0.162 ENST00000394052.3
KRT222
keratin 222
chr6_-_35109145 0.162 ENST00000373974.4
ENST00000244645.3
TCP11

t-complex 11, testis-specific

chr5_-_22853429 0.161 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr9_+_82188077 0.160 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_+_141418962 0.156 ENST00000493845.1
WEE2
WEE1 homolog 2 (S. pombe)
chr6_+_12290586 0.155 ENST00000379375.5
EDN1
endothelin 1
chr1_-_89736434 0.154 ENST00000370459.3
GBP5
guanylate binding protein 5
chr3_-_151034734 0.154 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr15_-_66797172 0.153 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4


ribosomal protein L4


chr4_+_104346194 0.151 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr19_-_10420459 0.150 ENST00000403352.1
ENST00000403903.3
ZGLP1

zinc finger, GATA-like protein 1

chr16_-_77465450 0.147 ENST00000562345.1
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr3_+_164924769 0.147 ENST00000494915.1
RP11-85M11.2
RP11-85M11.2
chr12_-_95510743 0.144 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr3_+_111260980 0.142 ENST00000438817.2
CD96
CD96 molecule
chr11_+_124481361 0.142 ENST00000284288.2
PANX3
pannexin 3
chr10_+_118187379 0.141 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr12_+_21284118 0.140 ENST00000256958.2
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr14_+_95048217 0.140 ENST00000557598.1
ENST00000556064.1
SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

chr5_-_36301984 0.136 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L


RAN binding protein 3-like


chr7_+_134464376 0.135 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr16_+_19619083 0.135 ENST00000538552.1
C16orf62
chromosome 16 open reading frame 62
chr16_+_25228242 0.135 ENST00000219660.5
AQP8
aquaporin 8
chr15_+_48483736 0.134 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr7_+_134464414 0.134 ENST00000361901.2
CALD1
caldesmon 1
chr22_-_30642782 0.133 ENST00000249075.3
LIF
leukemia inhibitory factor
chr14_-_60952739 0.133 ENST00000555476.1
ENST00000321731.3
C14orf39

chromosome 14 open reading frame 39

chr13_-_46679185 0.133 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr8_-_49834299 0.130 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr18_-_53177984 0.129 ENST00000543082.1
TCF4
transcription factor 4
chr1_+_16085263 0.129 ENST00000483633.2
ENST00000502739.1
ENST00000431771.2
FBLIM1


filamin binding LIM protein 1


chr17_-_2117600 0.127 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr7_+_35756066 0.125 ENST00000449644.1
AC018647.3
AC018647.3
chr15_+_66797627 0.124 ENST00000565627.1
ENST00000564179.1
ZWILCH

zwilch kinetochore protein

chr12_+_19389814 0.123 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr2_+_64073187 0.122 ENST00000491621.1
UGP2
UDP-glucose pyrophosphorylase 2
chr1_+_209859510 0.122 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr2_-_56274461 0.122 ENST00000446139.1
AC011306.2
AC011306.2
chrX_-_33146477 0.121 ENST00000378677.2
DMD
dystrophin
chr18_-_53069419 0.119 ENST00000570177.2
TCF4
transcription factor 4
chr15_-_83952071 0.119 ENST00000569704.1
BNC1
basonuclin 1
chr6_+_12007897 0.118 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr12_-_112443830 0.117 ENST00000550037.1
ENST00000549425.1
TMEM116

transmembrane protein 116

chr15_-_80263506 0.114 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr12_+_76653611 0.114 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chrX_+_135252050 0.114 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr2_+_242750274 0.112 ENST00000405370.1
NEU4
sialidase 4
chr1_+_11539204 0.112 ENST00000294484.6
ENST00000389575.3
PTCHD2

patched domain containing 2

chr6_+_32812568 0.111 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr17_+_7211656 0.109 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr5_-_142023766 0.108 ENST00000394496.2
FGF1
fibroblast growth factor 1 (acidic)
chr8_+_107738240 0.108 ENST00000449762.2
ENST00000297447.6
OXR1

oxidation resistance 1

chr7_+_35756400 0.108 ENST00000585952.1
AC018647.3
AC018647.3
chr15_+_66797455 0.108 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr3_-_100551141 0.108 ENST00000478235.1
ENST00000471901.1
ABI3BP

ABI family, member 3 (NESH) binding protein

chr12_-_94673956 0.107 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr18_+_39739223 0.107 ENST00000601948.1
LINC00907
long intergenic non-protein coding RNA 907
chr8_+_107738343 0.106 ENST00000521592.1
OXR1
oxidation resistance 1
chr3_-_99569821 0.106 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr2_+_66662249 0.105 ENST00000560281.2
MEIS1
Meis homeobox 1
chr3_-_20053741 0.105 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr7_+_21582638 0.105 ENST00000409508.3
ENST00000328843.6
DNAH11

dynein, axonemal, heavy chain 11

chr10_-_94301107 0.105 ENST00000436178.1
IDE
insulin-degrading enzyme
chr2_-_231989808 0.105 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr6_+_12718497 0.104 ENST00000379348.2
PHACTR1
phosphatase and actin regulator 1
chrX_+_135251835 0.104 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr15_+_91411810 0.104 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr12_+_20963632 0.103 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chrX_+_135251783 0.103 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr12_+_20963647 0.102 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr21_+_39644305 0.102 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_-_8021710 0.101 ENST00000380149.1
ENST00000448843.2
ALOXE3

arachidonate lipoxygenase 3

chr21_+_39644395 0.101 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_-_139866723 0.101 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr12_-_18243075 0.098 ENST00000536890.1
RERGL
RERG/RAS-like
chrX_-_154842589 0.098 ENST00000334398.3
TMLHE
trimethyllysine hydroxylase, epsilon
chr8_-_116504448 0.098 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr8_+_101349823 0.097 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chrX_-_154842538 0.097 ENST00000369439.4
TMLHE
trimethyllysine hydroxylase, epsilon
chr1_+_84630574 0.097 ENST00000413538.1
ENST00000417530.1
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr9_+_74920408 0.096 ENST00000451152.1
RP11-63P12.6
RP11-63P12.6
chr7_-_48068671 0.096 ENST00000297325.4
SUN3
Sad1 and UNC84 domain containing 3
chr10_+_17794251 0.095 ENST00000377495.1
ENST00000338221.5
TMEM236

transmembrane protein 236

chr8_-_116681686 0.095 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr5_-_39270725 0.094 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB


FYN binding protein


chr6_-_131321863 0.094 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr6_+_72922505 0.093 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_167059830 0.093 ENST00000367868.3
GPA33
glycoprotein A33 (transmembrane)
chr13_-_88323218 0.093 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG


MIR4500 host gene (non-protein coding)


chr13_+_53030107 0.093 ENST00000490903.1
ENST00000480747.1
CKAP2

cytoskeleton associated protein 2

chr6_+_167584081 0.093 ENST00000366832.2
TCP10L2
t-complex 10-like 2
chr3_-_138048682 0.092 ENST00000383180.2
NME9
NME/NM23 family member 9
chr2_+_74056147 0.091 ENST00000394070.2
ENST00000536064.1
STAMBP

STAM binding protein

chr12_-_11339543 0.091 ENST00000334266.1
TAS2R42
taste receptor, type 2, member 42
chr4_-_189030422 0.090 ENST00000536972.1
TRIML2
tripartite motif family-like 2
chr12_-_112443767 0.090 ENST00000550233.1
ENST00000546962.1
ENST00000550800.2
TMEM116


transmembrane protein 116


chr5_-_135290705 0.089 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr10_-_14050522 0.089 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chrY_+_3447082 0.088 ENST00000321217.4
ENST00000559055.2
TGIF2LY

TGFB-induced factor homeobox 2-like, Y-linked

chr13_-_21918947 0.088 ENST00000423575.1
LINC00539
LINC00539
chr7_-_111032971 0.086 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_23521222 0.086 ENST00000374619.1
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr12_+_49961990 0.086 ENST00000551063.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr2_+_220306238 0.086 ENST00000435853.1
SPEG
SPEG complex locus
chr8_+_118147498 0.085 ENST00000519688.1
ENST00000456015.2
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr13_+_46039037 0.085 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr13_+_103459704 0.085 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr2_+_163175394 0.084 ENST00000446271.1
ENST00000429691.2
GCA

grancalcin, EF-hand calcium binding protein

chr7_+_40174565 0.084 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10





succinylCoA:glutarate-CoA transferase





chr13_+_111748183 0.083 ENST00000422994.1
LINC00368
long intergenic non-protein coding RNA 368
chr2_-_217236750 0.083 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr9_-_35658007 0.083 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr3_-_67705006 0.083 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
SUCLG2


succinate-CoA ligase, GDP-forming, beta subunit


chr19_-_45982076 0.082 ENST00000423698.2
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr15_-_65407524 0.082 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr5_+_61874562 0.081 ENST00000409534.1
ENST00000334994.5
IPO11
LRRC70
importin 11
leucine rich repeat containing 70
chr1_-_92949505 0.081 ENST00000370332.1
GFI1
growth factor independent 1 transcription repressor
chr19_-_5785630 0.080 ENST00000590343.1
ENST00000586012.1
DUS3L
CTB-54O9.9
dihydrouridine synthase 3-like (S. cerevisiae)
Uncharacterized protein
chr1_+_202385953 0.080 ENST00000466968.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr10_+_96698406 0.079 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr14_-_65439132 0.079 ENST00000533601.2
RAB15
RAB15, member RAS oncogene family
chr1_+_84630645 0.079 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_157827841 0.079 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1




arginine/serine-rich coiled-coil 1




chr14_-_80782219 0.079 ENST00000553594.1
DIO2
deiodinase, iodothyronine, type II
chr7_-_48068699 0.078 ENST00000412142.1
ENST00000395572.2
SUN3

Sad1 and UNC84 domain containing 3

chr12_-_118796971 0.078 ENST00000542902.1
TAOK3
TAO kinase 3
chr6_+_12007963 0.077 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 0.7 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 1.0 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.6 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.4 GO:1904970 brush border assembly(GO:1904970)
0.1 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.2 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.2 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.2 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.0 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.0 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.0 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.1 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.0 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.0 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.2 GO:1990423 RZZ complex(GO:1990423)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 1.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.0 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.3 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.0 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.0 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_ALK1_PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 1.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 1.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins