Motif ID: HOXB6_PRRX2

Z-value: 0.824

Transcription factors associated with HOXB6_PRRX2:

Gene SymbolEntrez IDGene Name
HOXB6 ENSG00000108511.8 HOXB6
PRRX2 ENSG00000167157.9 PRRX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRRX2hg19_v2_chr9_+_132427883_132427951-0.722.8e-02Click!
HOXB6hg19_v2_chr17_-_46682321_466823620.225.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB6_PRRX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_55515400 0.962 ENST00000497027.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr8_+_85618155 0.929 ENST00000523850.1
ENST00000521376.1
RALYL

RALY RNA binding protein-like

chr7_-_84122033 0.861 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_55515202 0.811 ENST00000482079.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr6_-_10115007 0.780 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr12_+_54447637 0.733 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr3_-_55521323 0.681 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr10_+_77056134 0.651 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1

ZNF503 antisense RNA 1

chr11_+_123430948 0.580 ENST00000529432.1
ENST00000534764.1
GRAMD1B

GRAM domain containing 1B

chr13_-_36429763 0.567 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr14_-_75083313 0.554 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2

CTD-2207P18.2

chr11_+_131240373 0.552 ENST00000374791.3
ENST00000436745.1
NTM

neurotrimin

chr17_-_46688334 0.540 ENST00000239165.7
HOXB7
homeobox B7
chr7_-_84121858 0.515 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr18_-_53089723 0.457 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr8_+_104831472 0.457 ENST00000262231.10
ENST00000507740.1
RIMS2

regulating synaptic membrane exocytosis 2

chr12_+_54422142 0.447 ENST00000243108.4
HOXC6
homeobox C6
chr20_-_7921090 0.445 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr11_+_123396528 0.441 ENST00000322282.7
ENST00000529750.1
GRAMD1B

GRAM domain containing 1B

chr11_+_131240593 0.437 ENST00000539799.1
NTM
neurotrimin
chr18_-_22932080 0.434 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521


zinc finger protein 521


chr3_+_111717600 0.411 ENST00000273368.4
TAGLN3
transgelin 3
chr12_+_54410664 0.409 ENST00000303406.4
HOXC4
homeobox C4
chr17_-_46671323 0.405 ENST00000239151.5
HOXB5
homeobox B5
chr3_+_111717511 0.388 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr6_+_78400375 0.387 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr2_-_99871570 0.384 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2


lysozyme G-like 2


chr10_+_77056181 0.383 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1

ZNF503 antisense RNA 1

chr8_+_104831554 0.379 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr17_+_47448102 0.378 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr13_-_46716969 0.371 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_+_123396307 0.370 ENST00000456860.2
GRAMD1B
GRAM domain containing 1B
chr3_+_111718173 0.364 ENST00000494932.1
TAGLN3
transgelin 3
chr15_+_49715449 0.362 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr13_-_72441315 0.360 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1


dachshund homolog 1 (Drosophila)


chr3_+_25469802 0.358 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr3_+_25469724 0.355 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr18_-_22804637 0.353 ENST00000577775.1
ZNF521
zinc finger protein 521
chr1_-_159832438 0.352 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr2_+_66662510 0.348 ENST00000272369.9
ENST00000407092.2
MEIS1

Meis homeobox 1

chr8_-_122653630 0.347 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr3_+_111718036 0.343 ENST00000455401.2
TAGLN3
transgelin 3
chr2_-_177684007 0.339 ENST00000451851.1
AC092162.1
AC092162.1
chr5_+_166711804 0.319 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr17_+_74536115 0.316 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr8_+_77316233 0.316 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
RP11-706J10.3
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr12_+_54384370 0.314 ENST00000504315.1
HOXC6
homeobox C6
chr10_-_10504285 0.311 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr1_+_77333117 0.309 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr11_-_126810521 0.300 ENST00000530572.1
RP11-688I9.4
RP11-688I9.4
chr7_-_112727774 0.300 ENST00000297146.3
ENST00000501255.2
GPR85

G protein-coupled receptor 85

chr5_+_82767487 0.300 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr5_+_167182003 0.298 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr3_-_114477787 0.296 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_200715573 0.295 ENST00000420922.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr13_-_86373536 0.294 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr12_-_16762971 0.290 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_+_82767583 0.285 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr12_-_88423164 0.285 ENST00000298699.2
ENST00000550553.1
C12orf50

chromosome 12 open reading frame 50

chr5_-_22853429 0.284 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr2_+_66662690 0.284 ENST00000488550.1
MEIS1
Meis homeobox 1
chr1_+_84630053 0.280 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr5_+_167181917 0.279 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr17_-_77924627 0.276 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16





TBC1 domain family, member 16





chr4_-_186877481 0.276 ENST00000444781.1
ENST00000432655.1
SORBS2

sorbin and SH3 domain containing 2

chr1_+_84629976 0.275 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr12_-_122240792 0.270 ENST00000541657.1
ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
RHOF
AC084018.1





ras homolog family member F (in filopodia)
AC084018.1





chr1_-_242612779 0.270 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr12_-_86650045 0.262 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr18_-_53019208 0.260 ENST00000562607.1
TCF4
transcription factor 4
chr2_+_173724771 0.256 ENST00000538974.1
ENST00000540783.1
RAPGEF4

Rap guanine nucleotide exchange factor (GEF) 4

chr5_-_1882858 0.251 ENST00000511126.1
ENST00000231357.2
IRX4

iroquois homeobox 4

chr18_-_53089538 0.251 ENST00000566777.1
TCF4
transcription factor 4
chr8_-_82395461 0.244 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr14_-_80782219 0.243 ENST00000553594.1
DIO2
deiodinase, iodothyronine, type II
chr12_-_71031185 0.242 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr1_+_84630352 0.241 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_7698599 0.240 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr18_+_72922710 0.236 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr4_-_186877502 0.236 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr20_+_62795827 0.234 ENST00000328439.1
ENST00000536311.1
MYT1

myelin transcription factor 1

chr4_-_186877806 0.234 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr3_-_57233966 0.233 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr16_-_69385681 0.233 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chrM_+_10053 0.232 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr1_-_203055129 0.231 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr6_-_138820624 0.231 ENST00000343505.5
NHSL1
NHS-like 1
chr21_+_17909594 0.230 ENST00000441820.1
ENST00000602280.1
LINC00478

long intergenic non-protein coding RNA 478

chr10_-_62149433 0.230 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr8_+_104892639 0.226 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr1_+_84630574 0.226 ENST00000413538.1
ENST00000417530.1
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr8_-_37351344 0.225 ENST00000520422.1
RP11-150O12.1
RP11-150O12.1
chr5_-_121659052 0.221 ENST00000512105.1
CTD-2544H17.1
CTD-2544H17.1
chr5_+_66300464 0.217 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr12_-_71031220 0.215 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr17_-_2117600 0.212 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr10_-_118897567 0.212 ENST00000369206.5
VAX1
ventral anterior homeobox 1
chr2_-_60780607 0.210 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr3_-_114173530 0.210 ENST00000470311.1
ZBTB20
zinc finger and BTB domain containing 20
chr9_-_128246769 0.207 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr12_-_28124903 0.207 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr3_-_71353892 0.206 ENST00000484350.1
FOXP1
forkhead box P1
chr1_+_84630645 0.206 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_84630367 0.206 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_+_82188077 0.200 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_+_10476851 0.199 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr8_-_37351424 0.198 ENST00000522718.1
RP11-150O12.1
RP11-150O12.1
chr16_-_30102547 0.195 ENST00000279386.2
TBX6
T-box 6
chr17_-_46682321 0.195 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr12_+_86268065 0.195 ENST00000551529.1
ENST00000256010.6
NTS

neurotensin

chr1_+_107682629 0.195 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1






netrin G1






chr15_+_48483736 0.195 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr6_-_138893661 0.194 ENST00000427025.2
NHSL1
NHS-like 1
chr1_+_167298281 0.192 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chrX_+_16141667 0.192 ENST00000380289.2
GRPR
gastrin-releasing peptide receptor
chr10_-_61900762 0.191 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr5_-_88120083 0.191 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr9_-_123812542 0.191 ENST00000223642.1
C5
complement component 5
chr12_-_28125638 0.190 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr3_-_167191814 0.189 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr6_-_76782371 0.189 ENST00000369950.3
ENST00000369963.3
IMPG1

interphotoreceptor matrix proteoglycan 1

chr12_-_5352315 0.186 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr2_-_77749474 0.186 ENST00000409093.1
ENST00000409088.3
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr8_-_16424871 0.184 ENST00000518026.1
MSR1
macrophage scavenger receptor 1
chr12_+_9066472 0.184 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chrX_-_32173579 0.184 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD




dystrophin




chr4_-_176733377 0.182 ENST00000505375.1
GPM6A
glycoprotein M6A
chr1_-_100643765 0.182 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39


leucine rich repeat containing 39


chr5_-_58882219 0.182 ENST00000505453.1
ENST00000360047.5
PDE4D

phosphodiesterase 4D, cAMP-specific

chr4_+_155484103 0.181 ENST00000302068.4
FGB
fibrinogen beta chain
chr7_+_129847688 0.181 ENST00000297819.3
SSMEM1
serine-rich single-pass membrane protein 1
chr5_+_66300446 0.181 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_-_69402828 0.180 ENST00000460709.1
FRMD4B
FERM domain containing 4B
chr17_+_39261584 0.180 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr7_-_137039191 0.180 ENST00000438969.2
AC078842.3
AC078842.3
chr3_-_114477962 0.179 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_12717892 0.178 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr4_-_186733363 0.178 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr12_-_94673956 0.178 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr13_-_30683005 0.175 ENST00000413591.1
ENST00000432770.1
LINC00365

long intergenic non-protein coding RNA 365

chr12_-_16430619 0.175 ENST00000344941.3
SLC15A5
solute carrier family 15, member 5
chr6_-_130182410 0.175 ENST00000368143.1
TMEM244
transmembrane protein 244
chr12_-_43833515 0.174 ENST00000549670.1
ENST00000395541.2
ADAMTS20

ADAM metallopeptidase with thrombospondin type 1 motif, 20

chr12_+_20963632 0.174 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr5_+_91378410 0.173 ENST00000507217.1
RP11-348J24.2
RP11-348J24.2
chr9_+_82267508 0.173 ENST00000490347.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_-_33913708 0.172 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chrX_+_135251783 0.172 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr1_-_242612726 0.172 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr14_-_83262540 0.172 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr4_+_57276661 0.170 ENST00000598320.1
AC068620.1
Uncharacterized protein
chr12_+_6949964 0.169 ENST00000541978.1
ENST00000435982.2
GNB3

guanine nucleotide binding protein (G protein), beta polypeptide 3

chr4_+_88720698 0.167 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr5_-_145252531 0.166 ENST00000377976.1
GRXCR2
glutaredoxin, cysteine rich 2
chr6_+_72926145 0.166 ENST00000425662.2
ENST00000453976.2
RIMS1

regulating synaptic membrane exocytosis 1

chr1_+_62439037 0.166 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_+_162601774 0.166 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr6_-_170599561 0.165 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr10_-_62332357 0.165 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_+_20963647 0.164 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr3_+_111630451 0.163 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr5_-_169626104 0.162 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1

CTB-27N1.1

chr3_-_54962100 0.161 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr7_-_41742697 0.160 ENST00000242208.4
INHBA
inhibin, beta A
chr18_-_52989217 0.160 ENST00000570287.2
TCF4
transcription factor 4
chr3_-_78719376 0.160 ENST00000495961.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr15_+_54901540 0.158 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr17_+_74536164 0.157 ENST00000586148.1
PRCD
progressive rod-cone degeneration
chr14_+_97925151 0.157 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1


CTD-2506J14.1


chr17_-_4689727 0.156 ENST00000328739.5
ENST00000354194.4
VMO1

vitelline membrane outer layer 1 homolog (chicken)

chr16_+_7382745 0.156 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1



RNA binding protein, fox-1 homolog (C. elegans) 1



chr2_+_66662249 0.156 ENST00000560281.2
MEIS1
Meis homeobox 1
chr18_+_28956740 0.155 ENST00000308128.4
ENST00000359747.4
DSG4

desmoglein 4

chr16_+_87636474 0.155 ENST00000284262.2
JPH3
junctophilin 3
chr17_+_56833184 0.154 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr11_+_124481361 0.154 ENST00000284288.2
PANX3
pannexin 3
chr11_-_13461790 0.154 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr20_-_14318248 0.153 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr3_-_71294304 0.152 ENST00000498215.1
FOXP1
forkhead box P1
chr2_-_208030647 0.152 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_28410128 0.152 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chrX_+_135252050 0.152 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr6_+_130339710 0.151 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr15_+_57511609 0.150 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12


transcription factor 12


chr1_-_186430222 0.149 ENST00000391997.2
PDC
phosducin
chr2_-_77749336 0.149 ENST00000409282.1
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr9_+_2159850 0.149 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_-_115127611 0.149 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr4_+_71384257 0.146 ENST00000339336.4
AMTN
amelotin
chr3_+_142842128 0.146 ENST00000483262.1
RP11-80H8.4
RP11-80H8.4
chrX_+_16668278 0.146 ENST00000380200.3
S100G
S100 calcium binding protein G
chr13_+_32634993 0.146 ENST00000436046.1
FRY
furry homolog (Drosophila)
chrX_+_135251835 0.146 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr7_-_111428957 0.145 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chrM_+_9207 0.145 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr16_-_29910853 0.145 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr7_+_28452130 0.144 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr5_-_13944652 0.143 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr8_-_71157595 0.142 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr4_+_117220016 0.138 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.4 1.5 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 1.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.5 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.5 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.7 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:1903862 regulation of muscle atrophy(GO:0014735) positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.0 GO:0072025 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.8 GO:0097264 self proteolysis(GO:0097264)
0.0 0.0 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0035711 T-helper 1 cell activation(GO:0035711)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222) regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.0 GO:2000765 regulation of cytoplasmic translation(GO:2000765) negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.0 GO:0071415 response to caffeine(GO:0031000) cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.0 GO:1902075 cellular response to salt(GO:1902075) response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:1901205 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.5 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.0 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.0 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.0 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 1.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0015793 canalicular bile acid transport(GO:0015722) glycerol transport(GO:0015793) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0061009 common bile duct development(GO:0061009)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.0 GO:0060353 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.0 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0035640 exploration behavior(GO:0035640)
0.0 0.0 GO:0036292 DNA rewinding(GO:0036292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 2.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0042585 female germ cell nucleus(GO:0001674) germinal vesicle(GO:0042585)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.2 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.0 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 2.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.3 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 3.6 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 1.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events