Motif ID: HOXB5

Z-value: 0.197


Transcription factors associated with HOXB5:

Gene SymbolEntrez IDGene Name
HOXB5 ENSG00000120075.5 HOXB5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB5hg19_v2_chr17_-_46671323_46671323-0.674.8e-02Click!


Activity profile for motif HOXB5.

activity profile for motif HOXB5


Sorted Z-values histogram for motif HOXB5

Sorted Z-values for motif HOXB5



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_52715179 0.275 ENST00000293670.3
 KRT83
keratin 83
chr15_-_75017711 0.213 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
 CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr19_-_16045220 0.101 ENST00000326742.8
 CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr12_-_53614043 0.080 ENST00000338561.5
 RARG
retinoic acid receptor, gamma
chr12_-_53614155 0.077 ENST00000543726.1
 RARG
retinoic acid receptor, gamma
chr6_+_121756809 0.074 ENST00000282561.3
 GJA1
gap junction protein, alpha 1, 43kDa
chr16_-_9770700 0.057 ENST00000561538.1
 RP11-297M9.1
Uncharacterized protein
chr3_+_187420101 0.054 ENST00000449623.1
ENST00000437407.1
 RP11-211G3.3

Uncharacterized protein

chr2_+_17721937 0.052 ENST00000451533.1
 VSNL1
visinin-like 1
chr5_+_133842243 0.051 ENST00000515627.2
 AC005355.2
AC005355.2
chr14_-_24020858 0.049 ENST00000419474.3
 ZFHX2
zinc finger homeobox 2
chr2_-_188430478 0.044 ENST00000421427.1
 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_17721920 0.041 ENST00000295156.4
 VSNL1
visinin-like 1
chr8_+_91233711 0.039 ENST00000523283.1
ENST00000517400.1
 LINC00534

long intergenic non-protein coding RNA 534

chr9_-_112970436 0.039 ENST00000400613.4
 C9orf152
chromosome 9 open reading frame 152
chr7_-_102252038 0.037 ENST00000461209.1
 RASA4
RAS p21 protein activator 4
chr16_-_28936007 0.036 ENST00000568703.1
ENST00000567483.1
 RABEP2

rabaptin, RAB GTPase binding effector protein 2

chr1_+_154975110 0.035 ENST00000535420.1
ENST00000368426.3
 ZBTB7B

zinc finger and BTB domain containing 7B

chr8_-_33455268 0.033 ENST00000522982.1
 DUSP26
dual specificity phosphatase 26 (putative)
chr3_-_164914640 0.032 ENST00000241274.3
 SLITRK3
SLIT and NTRK-like family, member 3
chrX_+_100333709 0.031 ENST00000372930.4
 TMEM35
transmembrane protein 35
chr4_-_114900831 0.030 ENST00000315366.7
 ARSJ
arylsulfatase family, member J
chr17_-_29233769 0.030 ENST00000581216.1
 TEFM
transcription elongation factor, mitochondrial
chr6_-_97285336 0.028 ENST00000229955.3
ENST00000417980.1
 GPR63

G protein-coupled receptor 63

chr19_-_12267524 0.027 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
 ZNF625



zinc finger protein 625



chr3_-_195538760 0.025 ENST00000475231.1
 MUC4
mucin 4, cell surface associated
chr14_+_38660185 0.024 ENST00000555655.1
 CTD-2142D14.1
CTD-2142D14.1
chr12_+_56915713 0.023 ENST00000262031.5
ENST00000552247.2
 RBMS2

RNA binding motif, single stranded interacting protein 2

chr13_-_54706954 0.023 ENST00000606706.1
ENST00000607494.1
ENST00000427299.2
ENST00000423442.2
ENST00000451744.1
 LINC00458




long intergenic non-protein coding RNA 458




chr17_-_29233221 0.023 ENST00000580840.1
 TEFM
transcription elongation factor, mitochondrial
chr16_-_1821496 0.022 ENST00000564628.1
ENST00000563498.1
 NME3

NME/NM23 nucleoside diphosphate kinase 3

chr2_+_219283815 0.021 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
 VIL1


villin 1


chr5_+_67511524 0.021 ENST00000521381.1
ENST00000521657.1
 PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

chr12_+_56915776 0.021 ENST00000550726.1
ENST00000542360.1
 RBMS2

RNA binding motif, single stranded interacting protein 2

chr16_-_1821721 0.021 ENST00000219302.3
 NME3
NME/NM23 nucleoside diphosphate kinase 3
chr8_+_91233750 0.021 ENST00000523406.1
 LINC00534
long intergenic non-protein coding RNA 534
chr1_+_116915855 0.019 ENST00000295598.5
 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_-_195538728 0.019 ENST00000349607.4
ENST00000346145.4
 MUC4

mucin 4, cell surface associated

chr12_-_6798410 0.017 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
 ZNF384


zinc finger protein 384


chr1_+_157963391 0.017 ENST00000359209.6
ENST00000416935.2
 KIRREL

kin of IRRE like (Drosophila)

chr12_-_6798523 0.016 ENST00000319770.3
 ZNF384
zinc finger protein 384
chr14_-_102704783 0.015 ENST00000522534.1
 MOK
MOK protein kinase
chr6_-_31869769 0.015 ENST00000375527.2
 ZBTB12
zinc finger and BTB domain containing 12
chr2_-_47168850 0.015 ENST00000409207.1
 MCFD2
multiple coagulation factor deficiency 2
chr13_-_64650144 0.015 ENST00000456627.1
 LINC00355
long intergenic non-protein coding RNA 355
chr3_+_45986511 0.015 ENST00000458629.1
ENST00000457814.1
 CXCR6

chemokine (C-X-C motif) receptor 6

chr12_-_6798616 0.014 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
 ZNF384



zinc finger protein 384



chr12_+_57984943 0.014 ENST00000422156.3
 PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr2_-_47168906 0.013 ENST00000444761.2
ENST00000409147.1
 MCFD2

multiple coagulation factor deficiency 2

chr18_+_32558208 0.012 ENST00000436190.2
 MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr20_-_48184638 0.012 ENST00000244043.4
 PTGIS
prostaglandin I2 (prostacyclin) synthase
chr4_+_159122728 0.012 ENST00000505049.1
ENST00000505189.1
ENST00000511038.1
 TMEM144


transmembrane protein 144


chr7_-_102252589 0.012 ENST00000520042.1
 RASA4
RAS p21 protein activator 4
chr12_-_56101647 0.011 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
 ITGA7




integrin, alpha 7




chr1_+_145575227 0.011 ENST00000393046.2
ENST00000369299.3
ENST00000463514.2
 PIAS3


protein inhibitor of activated STAT, 3


chr19_-_50143452 0.011 ENST00000246792.3
 RRAS
related RAS viral (r-ras) oncogene homolog
chr1_+_145576007 0.010 ENST00000369298.1
 PIAS3
protein inhibitor of activated STAT, 3
chr17_-_17140436 0.010 ENST00000285071.4
ENST00000389169.5
ENST00000417064.1
 FLCN


folliculin


chr1_+_145575980 0.010 ENST00000393045.2
 PIAS3
protein inhibitor of activated STAT, 3
chr6_-_29395509 0.008 ENST00000377147.2
 OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr16_-_58004992 0.008 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
 CNGB1


cyclic nucleotide gated channel beta 1


chr1_-_155658260 0.008 ENST00000368339.5
ENST00000405763.3
ENST00000368340.5
ENST00000454523.1
ENST00000443231.1
ENST00000347088.5
ENST00000361831.5
ENST00000355499.4
 YY1AP1







YY1 associated protein 1







chr17_+_2496971 0.008 ENST00000397195.5
 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr1_+_155579979 0.008 ENST00000452804.2
ENST00000538143.1
ENST00000245564.2
ENST00000368341.4
 MSTO1



misato 1, mitochondrial distribution and morphology regulator



chr11_-_35440579 0.007 ENST00000606205.1
 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_-_155658085 0.007 ENST00000311573.5
ENST00000438245.2
 YY1AP1

YY1 associated protein 1

chr7_+_125557914 0.006 ENST00000411856.1
 AC005276.1
AC005276.1
chr18_+_32558380 0.006 ENST00000588349.2
 MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr6_-_29396243 0.005 ENST00000377148.1
 OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr6_-_32820529 0.005 ENST00000425148.2
 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_+_4662282 0.005 ENST00000381883.2
 PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr6_-_31510181 0.005 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
 DDX39B


DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B


chr19_-_42724261 0.005 ENST00000595337.1
 DEDD2
death effector domain containing 2
chr6_+_167525277 0.004 ENST00000400926.2
 CCR6
chemokine (C-C motif) receptor 6
chr6_+_30749649 0.004 ENST00000422944.1
 HCG20
HLA complex group 20 (non-protein coding)
chr3_+_51422478 0.004 ENST00000528157.1
 MANF
mesencephalic astrocyte-derived neurotrophic factor
chr1_+_162351503 0.004 ENST00000458626.2
 C1orf226
chromosome 1 open reading frame 226
chr1_-_155658766 0.004 ENST00000295566.4
ENST00000368330.2
 YY1AP1

YY1 associated protein 1

chr12_+_53693466 0.004 ENST00000267103.5
ENST00000548632.1
 C12orf10

chromosome 12 open reading frame 10

chr4_-_68620053 0.003 ENST00000420975.2
ENST00000226413.4
 GNRHR

gonadotropin-releasing hormone receptor

chr1_-_155658518 0.003 ENST00000404643.1
ENST00000359205.5
ENST00000407221.1
 YY1AP1


YY1 associated protein 1


chr11_-_57089671 0.003 ENST00000532437.1
 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr11_-_57089774 0.003 ENST00000527207.1
 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr8_-_93107443 0.003 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
 RUNX1T1







runt-related transcription factor 1; translocated to, 1 (cyclin D-related)







chr6_-_31509714 0.002 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
 DDX39B









DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B









chr3_+_190281229 0.002 ENST00000453359.1
 IL1RAP
interleukin 1 receptor accessory protein
chr8_-_93107696 0.002 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
 RUNX1T1


runt-related transcription factor 1; translocated to, 1 (cyclin D-related)


chr12_+_66217911 0.001 ENST00000403681.2
 HMGA2
high mobility group AT-hook 2
chr11_+_72281681 0.001 ENST00000450804.3
 RP11-169D4.1
RP11-169D4.1
chr7_+_120969045 0.001 ENST00000222462.2
 WNT16
wingless-type MMTV integration site family, member 16
chr16_+_31539183 0.000 ENST00000302312.4
 AHSP
alpha hemoglobin stabilizing protein
chr1_+_235491714 0.000 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
 GGPS1



geranylgeranyl diphosphate synthase 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0 0.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics