Motif ID: HOXB3

Z-value: 0.448


Transcription factors associated with HOXB3:

Gene SymbolEntrez IDGene Name
HOXB3 ENSG00000120093.7 HOXB3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB3hg19_v2_chr17_-_46667594_46667619-0.791.1e-02Click!


Activity profile for motif HOXB3.

activity profile for motif HOXB3


Sorted Z-values histogram for motif HOXB3

Sorted Z-values for motif HOXB3



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_25865159 0.666 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr18_+_61557781 0.456 ENST00000443281.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_+_121447469 0.384 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr9_+_470288 0.382 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr4_+_86525299 0.349 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr7_-_121944491 0.340 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr10_+_5090940 0.330 ENST00000602997.1
AKR1C3
aldo-keto reductase family 1, member C3
chr14_+_39944025 0.329 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr12_-_10022735 0.317 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr4_+_37455536 0.308 ENST00000381980.4
ENST00000508175.1
C4orf19

chromosome 4 open reading frame 19

chr6_+_47666275 0.304 ENST00000327753.3
ENST00000283303.2
GPR115

G protein-coupled receptor 115

chr1_+_28261492 0.302 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr18_+_61554932 0.295 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr2_+_65215604 0.283 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr2_+_191221240 0.276 ENST00000409027.1
ENST00000458193.1
INPP1

inositol polyphosphate-1-phosphatase

chr9_+_130911723 0.269 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr4_+_139230865 0.264 ENST00000502757.1
ENST00000507145.1
ENST00000515282.1
ENST00000510736.1
LINC00499



long intergenic non-protein coding RNA 499



chr2_-_70780572 0.258 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr9_+_12775011 0.257 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr9_+_130911770 0.249 ENST00000372998.1
LCN2
lipocalin 2
chr9_+_125133315 0.239 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr8_+_32579271 0.236 ENST00000518084.1
NRG1
neuregulin 1
chr11_+_5710919 0.233 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr1_+_81771806 0.216 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr8_-_17579726 0.215 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr5_+_36608422 0.213 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_92261516 0.209 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr2_+_8822113 0.201 ENST00000396290.1
ENST00000331129.3
ID2

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

chr7_-_92777606 0.201 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr17_-_40337470 0.197 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr4_+_66536248 0.197 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr17_+_62223320 0.193 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr4_-_52883786 0.191 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr7_-_99764853 0.189 ENST00000411994.1
ENST00000426974.2
GAL3ST4

galactose-3-O-sulfotransferase 4

chr12_-_10978957 0.186 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr4_+_87515454 0.183 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13


protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)


chr2_+_226273597 0.173 ENST00000409269.2
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr18_-_14970301 0.164 ENST00000580867.1
RP11-527H14.3
RP11-527H14.3
chr1_+_79115503 0.163 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr2_+_143635222 0.158 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU


kynureninase


chr7_-_100239132 0.157 ENST00000223051.3
ENST00000431692.1
TFR2

transferrin receptor 2

chr12_-_95945246 0.155 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr17_-_27418537 0.155 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr5_-_53115506 0.154 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1

CTD-2081C10.1

chr11_-_102714534 0.152 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr3_-_185538849 0.148 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_104905840 0.143 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr1_-_9953295 0.142 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr9_+_125132803 0.140 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_143635067 0.139 ENST00000264170.4
KYNU
kynureninase
chr6_+_26045603 0.131 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr8_-_30670384 0.127 ENST00000221138.4
ENST00000518243.1
PPP2CB

protein phosphatase 2, catalytic subunit, beta isozyme

chr2_+_28618532 0.123 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr12_-_15815626 0.120 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr11_-_119991589 0.120 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr8_-_41166953 0.114 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr12_-_6484376 0.112 ENST00000360168.3
ENST00000358945.3
SCNN1A

sodium channel, non-voltage-gated 1 alpha subunit

chr8_-_13134045 0.110 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr2_+_191208601 0.110 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1


inositol polyphosphate-1-phosphatase


chr12_+_16500037 0.109 ENST00000536371.1
ENST00000010404.2
MGST1

microsomal glutathione S-transferase 1

chr1_-_21620877 0.108 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr5_+_150639360 0.108 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr10_+_53806501 0.107 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr8_+_22132810 0.105 ENST00000356766.6
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr3_-_186288097 0.103 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr3_-_176914191 0.103 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1


transducin (beta)-like 1 X-linked receptor 1


chr2_+_191208656 0.101 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr3_+_186288454 0.100 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr1_-_21625486 0.100 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chrX_-_13835147 0.097 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr10_+_6779326 0.097 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr14_-_24711806 0.095 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2



TERF1 (TRF1)-interacting nuclear factor 2



chr11_-_102709441 0.095 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr3_+_43020773 0.094 ENST00000488863.1
FAM198A
family with sequence similarity 198, member A
chr15_+_41057818 0.094 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr4_-_40632844 0.092 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr14_-_24711865 0.091 ENST00000399423.4
ENST00000267415.7
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chrX_-_48824793 0.091 ENST00000376477.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr17_+_30348024 0.089 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
LRRC37B



leucine rich repeat containing 37B



chr14_-_24711764 0.088 ENST00000557921.1
ENST00000558476.1
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr11_+_101918153 0.087 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr7_-_99764907 0.086 ENST00000413800.1
GAL3ST4
galactose-3-O-sulfotransferase 4
chr8_-_623547 0.085 ENST00000522893.1
ERICH1
glutamate-rich 1
chr5_+_36608280 0.085 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_82462425 0.085 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr6_+_45296391 0.085 ENST00000371436.6
ENST00000576263.1
RUNX2

runt-related transcription factor 2

chr2_+_191208791 0.083 ENST00000423767.1
ENST00000451089.1
INPP1

inositol polyphosphate-1-phosphatase

chr16_-_28937027 0.083 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr4_-_66536196 0.081 ENST00000511294.1
EPHA5
EPH receptor A5
chr14_-_24711470 0.079 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr13_+_78315348 0.078 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr9_+_5231413 0.078 ENST00000239316.4
INSL4
insulin-like 4 (placenta)
chr12_-_123201337 0.077 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chrX_+_77166172 0.076 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr7_+_43152212 0.074 ENST00000453890.1
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr6_+_34204642 0.072 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr13_+_78315295 0.072 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr7_-_122339162 0.072 ENST00000340112.2
RNF133
ring finger protein 133
chrX_+_10031499 0.072 ENST00000454666.1
WWC3
WWC family member 3
chr11_+_118398178 0.071 ENST00000302783.4
ENST00000539546.1
TTC36

tetratricopeptide repeat domain 36

chr12_+_6419877 0.071 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr1_+_62439037 0.069 ENST00000545929.1
INADL
InaD-like (Drosophila)
chrX_+_154254960 0.066 ENST00000369498.3
FUNDC2
FUN14 domain containing 2
chr2_-_101925055 0.066 ENST00000295317.3
RNF149
ring finger protein 149
chr4_-_66536057 0.066 ENST00000273854.3
EPHA5
EPH receptor A5
chr4_-_40632881 0.065 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr5_-_159546396 0.065 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A


PWWP domain containing 2A


chr15_+_84841242 0.064 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr2_-_10587897 0.063 ENST00000405333.1
ENST00000443218.1
ODC1

ornithine decarboxylase 1

chr2_+_197577841 0.062 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr2_+_138722028 0.062 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr17_-_62208169 0.060 ENST00000606895.1
ERN1
endoplasmic reticulum to nucleus signaling 1
chr16_+_31724618 0.060 ENST00000530881.1
ENST00000529515.1
ZNF720

zinc finger protein 720

chr2_-_152590982 0.059 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
NEB


nebulin


chr7_+_43152191 0.058 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr8_-_13134246 0.058 ENST00000503161.2
DLC1
deleted in liver cancer 1
chr21_-_31986249 0.057 ENST00000329122.2
KRTAP6-1
keratin associated protein 6-1
chr1_+_160160346 0.057 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr16_-_28621353 0.057 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr14_-_100046444 0.057 ENST00000554996.1
CCDC85C
coiled-coil domain containing 85C
chr2_+_200820494 0.057 ENST00000435773.2
C2orf47
chromosome 2 open reading frame 47
chr5_-_108063949 0.057 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr16_-_3350614 0.057 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr11_-_124981475 0.056 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218











transmembrane protein 218











chr1_+_222910538 0.056 ENST00000434700.1
ENST00000445590.2
FAM177B

family with sequence similarity 177, member B

chr12_-_8088773 0.056 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr7_+_37723420 0.056 ENST00000476620.1
EPDR1
ependymin related 1
chr12_+_48592134 0.055 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr5_+_55149150 0.053 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr17_+_44372465 0.053 ENST00000393465.3
ENST00000320254.5
LRRC37A

leucine rich repeat containing 37A

chr12_-_23737534 0.053 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr2_+_44502597 0.053 ENST00000260649.6
ENST00000409387.1
SLC3A1

solute carrier family 3 (amino acid transporter heavy chain), member 1

chr11_+_67219867 0.052 ENST00000438189.2
CABP4
calcium binding protein 4
chr2_+_44502630 0.052 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
SLC3A1


solute carrier family 3 (amino acid transporter heavy chain), member 1


chr14_+_56584414 0.052 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr9_+_135937365 0.052 ENST00000372080.4
ENST00000351304.7
CEL

carboxyl ester lipase

chr3_-_105587879 0.051 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB


Cbl proto-oncogene B, E3 ubiquitin protein ligase


chr3_+_195447738 0.051 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20


mucin 20, cell surface associated


chr1_+_160160283 0.049 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_+_115177178 0.048 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr12_-_10605929 0.048 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr2_-_112237835 0.047 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG

MIR4435-1 host gene (non-protein coding)

chr15_+_78830023 0.047 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr16_-_28621298 0.047 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_74486109 0.047 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr14_+_61654271 0.046 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr12_+_7456880 0.046 ENST00000399422.4
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr10_-_22292613 0.046 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr8_+_22132847 0.046 ENST00000521356.1
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr3_-_105588231 0.046 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr4_+_40198527 0.044 ENST00000381799.5
RHOH
ras homolog family member H
chr22_+_24199113 0.044 ENST00000405847.1
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr17_+_40610862 0.044 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1








ATPase, H+ transporting, lysosomal V0 subunit a1








chr9_-_95166841 0.044 ENST00000262551.4
OGN
osteoglycin
chr5_+_36606700 0.043 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_8088871 0.042 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr3_-_151047327 0.042 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr2_+_187371440 0.042 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr5_-_140027357 0.042 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr8_+_39972170 0.041 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr4_+_144312659 0.040 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr12_-_123187890 0.040 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr7_+_99647411 0.040 ENST00000438937.1
ZSCAN21
zinc finger and SCAN domain containing 21
chr16_-_31085514 0.040 ENST00000300849.4
ZNF668
zinc finger protein 668
chr17_+_74846230 0.040 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr7_+_74379083 0.040 ENST00000361825.7
GATSL1
GATS protein-like 1
chr2_-_179516225 0.039 ENST00000446966.1
ENST00000426232.1
TTN

titin

chr17_+_35732955 0.039 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr9_+_124329336 0.038 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr1_+_207226574 0.037 ENST00000367080.3
ENST00000367079.2
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr5_+_61874696 0.036 ENST00000491184.2
LRRC70
leucine rich repeat containing 70
chr2_+_196313239 0.036 ENST00000413290.1
AC064834.1
AC064834.1
chr9_+_131062367 0.036 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr12_-_50643664 0.036 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr2_-_166060382 0.036 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr7_+_30589829 0.035 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr4_-_164534657 0.034 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr9_+_125133467 0.034 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_130587237 0.033 ENST00000520048.1
CCDC26
coiled-coil domain containing 26
chr6_+_26204825 0.032 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr4_+_110769258 0.031 ENST00000594814.1
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr3_-_143567262 0.031 ENST00000474151.1
ENST00000316549.6
SLC9A9

solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9

chr2_+_201242941 0.030 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr1_-_109935819 0.029 ENST00000538502.1
SORT1
sortilin 1
chr1_-_1710229 0.029 ENST00000341991.3
NADK
NAD kinase
chr7_+_99647389 0.028 ENST00000543588.1
ENST00000292450.4
ENST00000456748.2
ZSCAN21


zinc finger and SCAN domain containing 21


chr11_-_96076334 0.028 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr4_+_110736659 0.028 ENST00000394631.3
ENST00000226796.6
GAR1

GAR1 ribonucleoprotein

chr4_+_95128748 0.028 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr14_-_23058063 0.027 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1


defender against cell death 1


chrX_+_41548220 0.027 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr2_+_138721850 0.027 ENST00000329366.4
ENST00000280097.3
HNMT

histamine N-methyltransferase

chr5_+_110427983 0.026 ENST00000513710.2
ENST00000505303.1
WDR36

WD repeat domain 36

chr9_-_95166976 0.026 ENST00000447356.1
OGN
osteoglycin
chr14_-_54908043 0.026 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1




cornichon family AMPA receptor auxiliary protein 1




chr6_+_26087509 0.026 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr6_+_55192267 0.026 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr16_+_28763108 0.025 ENST00000357796.3
ENST00000550983.1
NPIPB9

nuclear pore complex interacting protein family, member B9

chrX_-_24690771 0.025 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr7_+_129015671 0.025 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.3 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.5 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.4 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.1 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.3 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0097179 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.3 GO:0045550 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism