Motif ID: HOXB2_UNCX_HOXD3

Z-value: 0.815

Transcription factors associated with HOXB2_UNCX_HOXD3:

Gene SymbolEntrez IDGene Name
HOXB2 ENSG00000173917.9 HOXB2
HOXD3 ENSG00000128652.7 HOXD3
UNCX ENSG00000164853.8 UNCX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB2hg19_v2_chr17_-_46623441_466234410.932.3e-04Click!
HOXD3hg19_v2_chr2_+_177015122_177015122-0.881.7e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB2_UNCX_HOXD3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_127898312 1.887 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr4_-_70653673 1.875 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr3_+_153599269 1.673 ENST00000463297.1
RP11-217E22.5
RP11-217E22.5
chr4_-_186570679 1.575 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr4_+_183065793 1.448 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr13_-_46716969 1.431 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_43968306 1.320 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr2_+_90248739 1.235 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr6_-_138866823 1.229 ENST00000342260.5
NHSL1
NHS-like 1
chr5_-_147286065 1.214 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr6_-_130182410 1.098 ENST00000368143.1
TMEM244
transmembrane protein 244
chr2_+_128293323 1.051 ENST00000389524.4
ENST00000428314.1
MYO7B

myosin VIIB

chr7_-_143929936 1.009 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr8_+_105235572 1.004 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr6_+_13272904 1.004 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr22_-_32651326 0.981 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr8_-_16424871 0.952 ENST00000518026.1
MSR1
macrophage scavenger receptor 1
chr20_-_7921090 0.907 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr11_-_26593779 0.889 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr3_-_151034734 0.877 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr15_+_48483736 0.876 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr11_-_26593677 0.843 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr2_-_68052694 0.830 ENST00000457448.1
AC010987.6
AC010987.6
chr13_+_77522632 0.822 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr22_-_33968239 0.821 ENST00000452586.2
ENST00000421768.1
LARGE

like-glycosyltransferase

chrX_-_114253536 0.782 ENST00000371936.1
IL13RA2
interleukin 13 receptor, alpha 2
chr4_+_71384257 0.781 ENST00000339336.4
AMTN
amelotin
chr21_-_42219065 0.777 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr11_-_26593649 0.763 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr4_-_186696425 0.747 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr4_+_71384300 0.742 ENST00000504451.1
AMTN
amelotin
chr13_-_36429763 0.722 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr4_-_70626314 0.715 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr15_+_54305101 0.707 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C


unc-13 homolog C (C. elegans)


chr12_+_52056548 0.666 ENST00000545061.1
ENST00000355133.3
SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

chr6_-_138833630 0.659 ENST00000533765.1
NHSL1
NHS-like 1
chr15_+_54901540 0.658 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr17_+_39261584 0.645 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr6_+_78400375 0.639 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr11_+_7618413 0.635 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_186696561 0.625 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr12_+_20963647 0.619 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr14_-_75083313 0.617 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2

CTD-2207P18.2

chr3_+_111717511 0.616 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr1_-_242612726 0.613 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr4_-_186696515 0.612 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr1_-_150738261 0.612 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr12_+_20963632 0.605 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr3_+_111717600 0.604 ENST00000273368.4
TAGLN3
transgelin 3
chr6_-_127780510 0.585 ENST00000487331.2
ENST00000483725.3
KIAA0408

KIAA0408

chr4_-_153601136 0.583 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr21_-_15918618 0.572 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr10_-_61899124 0.571 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_-_33913708 0.566 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr5_-_10761206 0.558 ENST00000432074.2
ENST00000230895.6
DAP

death-associated protein

chr12_-_22063787 0.555 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr7_-_111424462 0.550 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr9_-_75488984 0.549 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1


RP11-151D14.1


chr7_-_111424506 0.540 ENST00000450156.1
ENST00000494651.2
DOCK4

dedicator of cytokinesis 4

chr8_-_83589388 0.536 ENST00000522776.1
RP11-653B10.1
RP11-653B10.1
chr8_-_49833978 0.533 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr15_+_63188009 0.529 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr3_-_157217328 0.514 ENST00000392832.2
ENST00000543418.1
VEPH1

ventricular zone expressed PH domain-containing 1

chr10_-_61900762 0.506 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_242612779 0.503 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr2_+_89952792 0.497 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr1_-_48937821 0.496 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr19_+_56270380 0.496 ENST00000434937.2
RFPL4A
ret finger protein-like 4A
chr3_+_111718173 0.491 ENST00000494932.1
TAGLN3
transgelin 3
chr1_+_59486129 0.488 ENST00000438195.1
ENST00000424308.1
RP4-794H19.4

RP4-794H19.4

chrX_+_16668278 0.481 ENST00000380200.3
S100G
S100 calcium binding protein G
chrM_+_10053 0.480 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr2_-_31361543 0.470 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_76330355 0.460 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr12_+_26348246 0.451 ENST00000422622.2
SSPN
sarcospan
chr11_-_26744908 0.451 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr1_-_92952433 0.445 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr3_-_157221380 0.445 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr5_-_22853429 0.437 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr5_+_135394840 0.432 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr1_-_48937838 0.429 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr3_-_157221128 0.426 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr7_+_144015218 0.418 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr2_-_99871570 0.415 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2


lysozyme G-like 2


chr1_+_109265033 0.402 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr13_-_86373536 0.399 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr20_-_56647116 0.398 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1

RP13-379L11.1

chr6_-_116866773 0.394 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr2_-_61697862 0.385 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr1_+_107682629 0.385 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1






netrin G1






chr3_+_124223586 0.375 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr11_-_5323226 0.374 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr2_-_208031943 0.373 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr13_+_110958124 0.373 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr8_-_87242589 0.373 ENST00000419776.2
ENST00000297524.3
SLC7A13

solute carrier family 7 (anionic amino acid transporter), member 13

chr8_-_82395461 0.366 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr13_-_95131923 0.364 ENST00000377028.5
ENST00000446125.1
DCT

dopachrome tautomerase

chr10_+_94451574 0.363 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr6_+_72926145 0.361 ENST00000425662.2
ENST00000453976.2
RIMS1

regulating synaptic membrane exocytosis 1

chr3_-_157221357 0.360 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr4_-_186733363 0.358 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr13_-_41593425 0.354 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_-_26588634 0.349 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chr6_+_132455118 0.346 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr14_-_20801427 0.345 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1


cyclin B1 interacting protein 1, E3 ubiquitin protein ligase


chr3_-_108248169 0.344 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr18_+_71815743 0.337 ENST00000169551.6
ENST00000580087.1
TIMM21

translocase of inner mitochondrial membrane 21 homolog (yeast)

chr5_-_137475071 0.336 ENST00000265191.2
NME5
NME/NM23 family member 5
chr8_-_49834299 0.332 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr13_-_30160925 0.331 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_-_55677999 0.322 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr7_+_18329712 0.320 ENST00000433709.2
HDAC9
histone deacetylase 9
chr3_+_111718036 0.317 ENST00000455401.2
TAGLN3
transgelin 3
chr14_-_80697396 0.316 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr15_-_65407524 0.315 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr15_+_54793169 0.315 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr5_+_156607829 0.315 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr14_+_52164820 0.313 ENST00000554167.1
FRMD6
FERM domain containing 6
chr5_+_166711804 0.313 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr22_-_32766972 0.310 ENST00000382084.4
ENST00000382086.2
RFPL3S

RFPL3 antisense

chr10_-_62060232 0.308 ENST00000503925.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_38064198 0.307 ENST00000250448.2
FOXA1
forkhead box A1
chr8_-_10512569 0.307 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr5_+_82767487 0.306 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr16_-_67517716 0.306 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr5_+_82767583 0.304 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr10_-_14372870 0.302 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr3_+_111393501 0.300 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chrX_-_92928557 0.296 ENST00000373079.3
ENST00000475430.2
NAP1L3

nucleosome assembly protein 1-like 3

chr6_+_111408698 0.296 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr14_+_95027772 0.296 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4

SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

chr6_-_139613269 0.292 ENST00000358430.3
TXLNB
taxilin beta
chr13_-_46626847 0.285 ENST00000242848.4
ENST00000282007.3
ZC3H13

zinc finger CCCH-type containing 13

chr6_+_130339710 0.283 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr13_+_49551020 0.280 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr17_-_46690839 0.280 ENST00000498634.2
HOXB8
homeobox B8
chr20_+_60174827 0.279 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr19_+_56280507 0.279 ENST00000341750.4
RFPL4AL1
ret finger protein-like 4A-like 1
chr8_+_77318769 0.273 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr17_-_73937116 0.270 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
FBF1


Fas (TNFRSF6) binding factor 1


chr5_+_174151536 0.270 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr11_-_7698453 0.270 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr4_+_183370146 0.269 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr1_+_81106951 0.268 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr3_+_140981456 0.268 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr8_+_107460147 0.268 ENST00000442977.2
OXR1
oxidation resistance 1
chr2_-_27498208 0.267 ENST00000424577.1
ENST00000426569.1
SLC30A3

solute carrier family 30 (zinc transporter), member 3

chr18_-_61311485 0.266 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4


serpin peptidase inhibitor, clade B (ovalbumin), member 4


chr1_+_152178320 0.264 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr13_+_33160553 0.264 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr12_-_75784669 0.264 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2



calcyphosine 2



chr10_-_62332357 0.262 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr9_-_107754034 0.255 ENST00000457720.1
RP11-217B7.3
RP11-217B7.3
chr1_+_76540386 0.255 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr15_-_61521495 0.254 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr18_+_50278430 0.253 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC


deleted in colorectal carcinoma


chrX_-_84634737 0.252 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr17_-_42908155 0.250 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1


gap junction protein, gamma 1, 45kDa


chr14_+_100485712 0.249 ENST00000544450.2
EVL
Enah/Vasp-like
chr18_-_68004529 0.247 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr6_-_119031228 0.246 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L


centrosomal protein 85kDa-like


chr10_-_105110831 0.245 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr3_+_111630451 0.243 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chrX_-_84634708 0.241 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr6_+_12007897 0.240 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr7_-_44122063 0.240 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM




polymerase (DNA directed), mu




chr21_-_19775973 0.240 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr18_+_6774000 0.238 ENST00000532723.1
ARHGAP28
Rho GTPase activating protein 28
chr5_+_20616500 0.236 ENST00000512688.1
RP11-774D14.1
RP11-774D14.1
chr5_+_121647386 0.236 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
SNCAIP



synuclein, alpha interacting protein



chr20_+_15177480 0.236 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr6_+_134758827 0.234 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr5_+_136070614 0.233 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr6_+_4087664 0.233 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr11_-_5364809 0.232 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr12_+_21284118 0.232 ENST00000256958.2
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr3_+_158787041 0.232 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr10_-_127505167 0.232 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr15_+_75303993 0.232 ENST00000564779.1
SCAMP5
secretory carrier membrane protein 5
chr1_+_109256067 0.230 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr17_+_67590125 0.230 ENST00000591334.1
AC003051.1
AC003051.1
chr6_-_170151603 0.230 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr22_-_32767017 0.229 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr3_-_46608010 0.229 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr19_-_54604083 0.228 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR





osteoclast associated, immunoglobulin-like receptor





chr20_+_44258165 0.228 ENST00000372643.3
WFDC10A
WAP four-disulfide core domain 10A
chr2_-_227050079 0.228 ENST00000423838.1
AC068138.1
AC068138.1
chr16_+_56260291 0.227 ENST00000563440.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr2_+_204571375 0.227 ENST00000374478.4
CD28
CD28 molecule
chr10_-_17171785 0.227 ENST00000377823.1
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr19_+_54466179 0.225 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr19_-_36001113 0.224 ENST00000434389.1
DMKN
dermokine
chr12_+_9066472 0.223 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr10_+_120116527 0.223 ENST00000445161.1
LINC00867
long intergenic non-protein coding RNA 867
chr12_+_28410128 0.223 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr1_+_153746683 0.222 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr2_-_74618907 0.219 ENST00000421392.1
ENST00000437375.1
DCTN1

dynactin 1

chr10_+_67330096 0.219 ENST00000433152.4
ENST00000601979.1
ENST00000599409.1
ENST00000608678.1
RP11-222A11.1



RP11-222A11.1



chr10_-_50396407 0.219 ENST00000374153.2
ENST00000374151.3
C10orf128

chromosome 10 open reading frame 128

chr4_-_176812842 0.218 ENST00000507540.1
GPM6A
glycoprotein M6A

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.3 0.9 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 1.6 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 1.1 GO:1904970 brush border assembly(GO:1904970)
0.2 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 1.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.8 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.6 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.4 GO:1903045 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) neural crest cell migration involved in sympathetic nervous system development(GO:1903045) facioacoustic ganglion development(GO:1903375)
0.1 2.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.3 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.4 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 4.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.0 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.8 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.6 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.1 1.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.6 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.1 GO:0050777 negative regulation of immune response(GO:0050777)
0.1 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.2 GO:1902523 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.3 GO:0061107 seminal vesicle development(GO:0061107)
0.0 1.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.2 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.4 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.0 0.2 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 1.0 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.0 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0060490 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 1.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:1904823 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.0 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) regulation of osteoclast proliferation(GO:0090289) positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.3 GO:0061458 reproductive system development(GO:0061458)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0001704 formation of primary germ layer(GO:0001704)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 1.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 3.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.5 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.1 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0046166 xylulose metabolic process(GO:0005997) pentose biosynthetic process(GO:0019322) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.0 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.0 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.0 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.0 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.0 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.0 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.0 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.1 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
0.0 0.4 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.1 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0097224 sperm connecting piece(GO:0097224)
0.2 1.7 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 2.2 GO:0043194 axon initial segment(GO:0043194)
0.1 0.3 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.3 GO:0071547 piP-body(GO:0071547)
0.0 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 4.0 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 1.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.0 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0034358 protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 2.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 4.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.1 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.3 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.6 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.1 GO:0010181 FMN binding(GO:0010181)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.4 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.9 GO:0003823 antigen binding(GO:0003823)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 1.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.1 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 3.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.0 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.1 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.1 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.4 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.0 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 2.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.7 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 2.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.7 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.8 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.7 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK