Motif ID: HOXA6

Z-value: 0.432


Transcription factors associated with HOXA6:

Gene SymbolEntrez IDGene Name
HOXA6 ENSG00000106006.6 HOXA6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXA6hg19_v2_chr7_-_27187393_271873930.196.2e-01Click!


Activity profile for motif HOXA6.

activity profile for motif HOXA6


Sorted Z-values histogram for motif HOXA6

Sorted Z-values for motif HOXA6



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_114055052 1.150 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr2_-_145188137 1.029 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr14_-_54418598 0.709 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr2_-_145278475 0.574 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_-_88179302 0.501 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr14_-_54423529 0.463 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr1_+_170632250 0.434 ENST00000367760.3
PRRX1
paired related homeobox 1
chr5_-_88120151 0.397 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr5_-_88119580 0.356 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr5_-_88120083 0.353 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr2_+_182850551 0.330 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr2_+_182850743 0.315 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr12_-_24103954 0.291 ENST00000441133.2
ENST00000545921.1
SOX5

SRY (sex determining region Y)-box 5

chr1_+_81771806 0.273 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr8_+_92261516 0.270 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr4_-_41884620 0.267 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr5_+_59783540 0.256 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chrX_-_15683147 0.234 ENST00000380342.3
TMEM27
transmembrane protein 27
chr10_-_92681033 0.233 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr2_+_210444142 0.228 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr2_+_210444748 0.223 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr10_-_102989551 0.222 ENST00000370193.2
LBX1
ladybird homeobox 1
chr2_-_145277569 0.219 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_177684007 0.213 ENST00000451851.1
AC092162.1
AC092162.1
chr10_+_118083919 0.213 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr4_-_36245561 0.201 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_-_72268721 0.200 ENST00000419131.1
ENST00000388743.2
EYA1

eyes absent homolog 1 (Drosophila)

chr9_+_77230499 0.188 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr10_+_24755416 0.184 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr10_+_11047259 0.183 ENST00000379261.4
ENST00000416382.2
CELF2

CUGBP, Elav-like family member 2

chr2_+_210444298 0.183 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr10_-_21786179 0.180 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr11_-_8285405 0.178 ENST00000335790.3
ENST00000534484.1
LMO1

LIM domain only 1 (rhombotin 1)

chr2_+_210443993 0.176 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr3_+_173302222 0.174 ENST00000361589.4
NLGN1
neuroligin 1
chr2_-_233641265 0.172 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr5_+_173930676 0.172 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chr6_-_10412600 0.171 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr7_-_14026063 0.167 ENST00000443608.1
ENST00000438956.1
ETV1

ets variant 1

chr2_+_162272605 0.165 ENST00000389554.3
TBR1
T-box, brain, 1
chr10_+_24528108 0.164 ENST00000438429.1
KIAA1217
KIAA1217
chr7_-_14026123 0.163 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1


ets variant 1


chr11_-_36619771 0.160 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr1_-_53608249 0.157 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr8_-_72268968 0.149 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr8_-_18744528 0.148 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr8_-_72268889 0.147 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr6_+_45296048 0.142 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2



runt-related transcription factor 2



chr11_-_27723158 0.141 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr18_+_32073253 0.140 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA


dystrobrevin, alpha


chr2_+_28618532 0.139 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr12_-_16761007 0.137 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr4_-_41884582 0.136 ENST00000499082.2
LINC00682
long intergenic non-protein coding RNA 682
chr4_+_96012585 0.132 ENST00000502683.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr18_+_32173276 0.132 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr3_+_69985734 0.131 ENST00000314557.6
ENST00000394351.3
MITF

microphthalmia-associated transcription factor

chr3_+_69928256 0.128 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr3_+_69985792 0.124 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr5_-_124082279 0.124 ENST00000513986.1
ZNF608
zinc finger protein 608
chr3_-_69402828 0.122 ENST00000460709.1
FRMD4B
FERM domain containing 4B
chr12_-_24103841 0.121 ENST00000541847.1
SOX5
SRY (sex determining region Y)-box 5
chr5_-_124084493 0.120 ENST00000509799.1
ZNF608
zinc finger protein 608
chr4_+_160188889 0.118 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr12_-_13248562 0.118 ENST00000457134.2
ENST00000537302.1
GSG1

germ cell associated 1

chr4_+_71494461 0.117 ENST00000396073.3
ENAM
enamelin
chr6_-_9939552 0.116 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr12_-_16762971 0.113 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_53608289 0.110 ENST00000371491.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr6_+_21593972 0.109 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr6_+_136172820 0.106 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr4_+_96012614 0.106 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr9_+_2717502 0.105 ENST00000382082.3
KCNV2
potassium channel, subfamily V, member 2
chr3_+_69812877 0.104 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr5_+_138209688 0.103 ENST00000518381.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr2_+_177015950 0.103 ENST00000306324.3
HOXD4
homeobox D4
chr12_-_13248732 0.100 ENST00000396302.3
GSG1
germ cell associated 1
chr3_+_69812701 0.098 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr11_-_8290263 0.095 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr1_+_12538594 0.095 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr4_+_41258786 0.094 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1



ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)



chr10_-_106240032 0.094 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr5_-_124081008 0.093 ENST00000306315.5
ZNF608
zinc finger protein 608
chr13_-_67802549 0.093 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr4_+_100495864 0.092 ENST00000265517.5
ENST00000422897.2
MTTP

microsomal triglyceride transfer protein

chr7_-_115670792 0.091 ENST00000265440.7
ENST00000393485.1
TFEC

transcription factor EC

chr12_-_16758873 0.089 ENST00000535535.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_13248705 0.088 ENST00000396310.2
GSG1
germ cell associated 1
chr4_+_41614720 0.088 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr5_+_173316341 0.087 ENST00000520867.1
ENST00000334035.5
CPEB4

cytoplasmic polyadenylation element binding protein 4

chr12_-_16758835 0.087 ENST00000541295.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_38557561 0.087 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr11_+_115498761 0.085 ENST00000424313.2
AP000997.1
AP000997.1
chr4_+_41614909 0.084 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr8_-_70745575 0.084 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_-_10415470 0.083 ENST00000379604.2
ENST00000379613.3
TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

chr2_+_102508955 0.082 ENST00000414004.2
FLJ20373
FLJ20373
chr2_+_33359473 0.082 ENST00000432635.1
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_166428839 0.081 ENST00000342316.4
CSRNP3
cysteine-serine-rich nuclear protein 3
chr2_-_164592497 0.081 ENST00000333129.3
ENST00000409634.1
FIGN

fidgetin

chr2_+_33359687 0.080 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr17_-_47045949 0.079 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr4_-_40516560 0.078 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr1_+_62439037 0.078 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr9_-_124989804 0.077 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr6_-_32157947 0.077 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr14_-_57197224 0.077 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3

Uncharacterized protein

chr2_+_33359646 0.076 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr10_-_21806759 0.075 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr11_-_16419067 0.074 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr6_-_10415218 0.073 ENST00000466073.1
ENST00000498450.1
TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

chr9_-_13165457 0.073 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr2_+_176987088 0.073 ENST00000249499.6
HOXD9
homeobox D9
chr2_+_226265364 0.072 ENST00000272907.6
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr2_+_173955327 0.071 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr10_-_33623310 0.070 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1



neuropilin 1



chr3_-_65583561 0.069 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr8_-_18541603 0.069 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr11_+_128563652 0.069 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_-_115670804 0.069 ENST00000320239.7
TFEC
transcription factor EC
chr4_+_160188306 0.068 ENST00000510510.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr12_-_16759440 0.068 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_115910091 0.065 ENST00000257414.8
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_-_177502659 0.065 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr12_-_13248598 0.064 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr2_-_175711133 0.064 ENST00000409597.1
ENST00000413882.1
CHN1

chimerin 1

chr1_-_98515395 0.063 ENST00000424528.2
MIR137HG
MIR137 host gene (non-protein coding)
chr12_-_53994805 0.063 ENST00000328463.7
ATF7
activating transcription factor 7
chr4_+_160203650 0.061 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr18_-_24237339 0.059 ENST00000580191.1
KCTD1
potassium channel tetramerization domain containing 1
chr20_+_11898507 0.057 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr17_-_39123144 0.057 ENST00000355612.2
KRT39
keratin 39
chr12_-_89746264 0.055 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr1_-_203055129 0.055 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr4_+_129730839 0.054 ENST00000511647.1
PHF17
jade family PHD finger 1
chr17_-_46262541 0.054 ENST00000579336.1
SKAP1
src kinase associated phosphoprotein 1
chr6_+_45296391 0.054 ENST00000371436.6
ENST00000576263.1
RUNX2

runt-related transcription factor 2

chr17_-_39150385 0.053 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr10_-_116418053 0.052 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr4_+_88720698 0.051 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr13_-_46425865 0.051 ENST00000400405.2
SIAH3
siah E3 ubiquitin protein ligase family member 3
chr3_-_54962100 0.051 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr8_-_25281747 0.051 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr11_+_22696314 0.050 ENST00000532398.1
ENST00000433790.1
GAS2

growth arrest-specific 2

chr1_+_87797351 0.049 ENST00000370542.1
LMO4
LIM domain only 4
chr15_-_54025300 0.049 ENST00000559418.1
WDR72
WD repeat domain 72
chr14_-_98444438 0.049 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chr8_-_95449155 0.048 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr7_+_66800928 0.047 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr4_+_74269956 0.046 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB




albumin




chr12_-_89746173 0.046 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr9_+_125796806 0.046 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr1_-_186430222 0.046 ENST00000391997.2
PDC
phosducin
chr15_+_48051920 0.044 ENST00000559196.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr8_+_9953214 0.042 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr14_+_97925151 0.042 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1


CTD-2506J14.1


chr4_-_111563076 0.041 ENST00000354925.2
ENST00000511990.1
PITX2

paired-like homeodomain 2

chr8_+_9953061 0.041 ENST00000522907.1
ENST00000528246.1
MSRA

methionine sulfoxide reductase A

chr18_-_31628558 0.040 ENST00000535384.1
NOL4
nucleolar protein 4
chr17_+_39846114 0.039 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr12_-_92536433 0.039 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr5_-_76935513 0.038 ENST00000306422.3
OTP
orthopedia homeobox
chr11_+_128562372 0.038 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_-_56082455 0.038 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr6_+_42584847 0.037 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr5_+_59783941 0.036 ENST00000506884.1
ENST00000504876.2
PART1

prostate androgen-regulated transcript 1 (non-protein coding)

chr4_+_129731074 0.036 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
PHF17


jade family PHD finger 1


chr5_+_140710061 0.035 ENST00000517417.1
ENST00000378105.3
PCDHGA1

protocadherin gamma subfamily A, 1

chr13_-_103053946 0.034 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr12_-_16430619 0.034 ENST00000344941.3
SLC15A5
solute carrier family 15, member 5
chr12_-_16758304 0.034 ENST00000320122.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_94673956 0.034 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr5_-_130868688 0.033 ENST00000504575.1
ENST00000513227.1
RAPGEF6

Rap guanine nucleotide exchange factor (GEF) 6

chr8_+_77596014 0.033 ENST00000523885.1
ZFHX4
zinc finger homeobox 4
chr11_+_110001723 0.033 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr12_-_16759711 0.030 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_-_46293378 0.030 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr1_+_168250194 0.028 ENST00000367821.3
TBX19
T-box 19
chr6_+_15401075 0.028 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr7_+_107332334 0.028 ENST00000541474.1
ENST00000544569.1
SLC26A4

solute carrier family 26 (anion exchanger), member 4

chr3_-_27764190 0.027 ENST00000537516.1
EOMES
eomesodermin
chr12_-_16762802 0.026 ENST00000534946.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_-_66417107 0.024 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr7_-_5463175 0.024 ENST00000399537.4
ENST00000430969.1
TNRC18

trinucleotide repeat containing 18

chr4_-_111563279 0.024 ENST00000511837.1
PITX2
paired-like homeodomain 2
chr17_-_46692287 0.024 ENST00000239144.4
HOXB8
homeobox B8
chr9_-_124990680 0.024 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr4_+_129730947 0.023 ENST00000452328.2
ENST00000504089.1
PHF17

jade family PHD finger 1

chr5_-_1882858 0.023 ENST00000511126.1
ENST00000231357.2
IRX4

iroquois homeobox 4

chr11_-_11374904 0.023 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr12_-_16758059 0.022 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_+_80838126 0.021 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr8_+_55528627 0.020 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr5_+_173930710 0.020 ENST00000511707.1
RP11-267A15.1
RP11-267A15.1
chr22_-_36236623 0.019 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_+_129015671 0.019 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr1_-_217250231 0.018 ENST00000493748.1
ENST00000463665.1
ESRRG

estrogen-related receptor gamma

chr18_+_59000815 0.018 ENST00000262717.4
CDH20
cadherin 20, type 2
chr10_-_10504285 0.017 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr2_+_54785485 0.017 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr18_+_20714525 0.017 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 1.2 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.6 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.8 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.7 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.3 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0098942 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746) cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.0 0.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0003289 atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0035993 deltoid tuberosity development(GO:0035993)
0.0 0.0 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0014878 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets