Motif ID: HOXA1

Z-value: 0.658


Transcription factors associated with HOXA1:

Gene SymbolEntrez IDGene Name
HOXA1 ENSG00000105991.7 HOXA1



Activity profile for motif HOXA1.

activity profile for motif HOXA1


Sorted Z-values histogram for motif HOXA1

Sorted Z-values for motif HOXA1



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_10697895 1.648 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2




adaptor-related protein complex 1, mu 2 subunit




chr19_-_51192661 1.644 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr17_+_39975544 1.628 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_39975455 1.608 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr1_+_43766668 0.769 ENST00000441333.2
ENST00000538015.1
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr20_-_36794938 0.734 ENST00000453095.1
TGM2
transglutaminase 2
chr20_-_36794902 0.705 ENST00000373403.3
TGM2
transglutaminase 2
chr16_+_28303804 0.647 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr5_+_167181917 0.603 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr5_+_159656437 0.535 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr5_+_166711804 0.519 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr17_+_40932610 0.453 ENST00000246914.5
WNK4
WNK lysine deficient protein kinase 4
chr11_-_65641044 0.416 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr12_-_55378470 0.415 ENST00000524668.1
ENST00000533607.1
TESPA1

thymocyte expressed, positive selection associated 1

chr12_-_95510743 0.414 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr11_-_93583697 0.412 ENST00000409977.1
VSTM5
V-set and transmembrane domain containing 5
chr10_-_5638048 0.401 ENST00000478294.1
RP13-463N16.6
RP13-463N16.6
chr17_+_61554413 0.400 ENST00000538928.1
ENST00000290866.4
ENST00000428043.1
ACE


angiotensin I converting enzyme


chr2_-_75788038 0.400 ENST00000393913.3
ENST00000410113.1
EVA1A

eva-1 homolog A (C. elegans)

chr1_+_205473720 0.397 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18


cyclin-dependent kinase 18


chr2_-_75788428 0.395 ENST00000432649.1
EVA1A
eva-1 homolog A (C. elegans)
chr2_-_75788424 0.394 ENST00000410071.1
EVA1A
eva-1 homolog A (C. elegans)
chr2_-_71062938 0.394 ENST00000410009.3
CD207
CD207 molecule, langerin
chr12_-_55378452 0.378 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr3_+_111260980 0.363 ENST00000438817.2
CD96
CD96 molecule
chr3_-_71774516 0.332 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr6_+_151561506 0.322 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_151561085 0.317 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_90272488 0.304 ENST00000485637.1
ENST00000522705.1
ANKRD6

ankyrin repeat domain 6

chr7_-_559853 0.295 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr11_+_60739249 0.295 ENST00000542157.1
ENST00000433107.2
ENST00000452451.2
ENST00000352009.5
CD6



CD6 molecule



chr17_-_40835076 0.286 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr20_-_30458491 0.278 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr11_+_7626950 0.277 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_107682629 0.264 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1






netrin G1






chr14_+_21569245 0.262 ENST00000556585.2
TMEM253
transmembrane protein 253
chr6_+_90272027 0.256 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr3_+_125985620 0.251 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1

RP11-71E19.1

chr11_-_72353494 0.249 ENST00000544570.1
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr11_-_72353451 0.248 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr12_+_57610562 0.237 ENST00000349394.5
NXPH4
neurexophilin 4
chr7_-_3214287 0.232 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr1_+_2005425 0.213 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr11_+_58938903 0.207 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr1_-_40098672 0.205 ENST00000535435.1
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr20_-_30458354 0.205 ENST00000428829.1
DUSP15
dual specificity phosphatase 15
chr10_-_79397391 0.203 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr22_-_22641542 0.202 ENST00000606654.1
LL22NC03-2H8.5
LL22NC03-2H8.5
chr5_+_36152091 0.201 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr15_+_81591757 0.199 ENST00000558332.1
IL16
interleukin 16
chr7_+_141418962 0.197 ENST00000493845.1
WEE2
WEE1 homolog 2 (S. pombe)
chr11_-_126870655 0.196 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr6_+_90272339 0.196 ENST00000522779.1
ANKRD6
ankyrin repeat domain 6
chr5_+_54398463 0.193 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr6_-_142409936 0.188 ENST00000258042.1
NMBR
neuromedin B receptor
chr2_-_70189397 0.186 ENST00000320256.4
ASPRV1
aspartic peptidase, retroviral-like 1
chr1_-_241520385 0.185 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr1_+_162601774 0.184 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr5_+_36152179 0.183 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2


S-phase kinase-associated protein 2, E3 ubiquitin protein ligase


chr6_-_36725157 0.182 ENST00000393189.2
CPNE5
copine V
chr16_+_15596123 0.182 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr5_+_158737824 0.182 ENST00000521472.1
AC008697.1
AC008697.1
chr3_+_159570722 0.181 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr17_-_38821373 0.177 ENST00000394052.3
KRT222
keratin 222
chr1_-_205391178 0.174 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr6_+_32006042 0.174 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr5_+_36152163 0.172 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_+_5509915 0.169 ENST00000322641.5
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr3_+_44916098 0.164 ENST00000296125.4
TGM4
transglutaminase 4
chr13_-_20077417 0.163 ENST00000382978.1
ENST00000400230.2
ENST00000255310.6
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr3_+_111260954 0.162 ENST00000283285.5
CD96
CD96 molecule
chr20_+_60174827 0.160 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr2_-_190044480 0.158 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr20_+_31669333 0.157 ENST00000375483.3
BPIFB4
BPI fold containing family B, member 4
chr3_+_159557637 0.154 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr3_+_111260856 0.153 ENST00000352690.4
CD96
CD96 molecule
chr3_+_127872265 0.153 ENST00000254730.6
ENST00000483457.1
EEFSEC

eukaryotic elongation factor, selenocysteine-tRNA-specific

chr17_-_8027402 0.150 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7


hes family bHLH transcription factor 7


chr10_-_28270795 0.149 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr2_-_239148599 0.146 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6






hes family bHLH transcription factor 6






chr3_+_150264555 0.145 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr5_+_157602404 0.145 ENST00000522975.1
CTC-436K13.1
CTC-436K13.1
chr12_+_75728419 0.141 ENST00000378695.4
ENST00000312442.2
GLIPR1L1

GLI pathogenesis-related 1 like 1

chr12_-_86650045 0.139 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_-_74501310 0.137 ENST00000423167.2
ENST00000432245.2
STRA6

stimulated by retinoic acid 6

chr6_+_80129989 0.135 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr17_-_44896047 0.135 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr21_-_46340884 0.132 ENST00000302347.5
ENST00000517819.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr1_+_45140400 0.132 ENST00000453711.1
C1orf228
chromosome 1 open reading frame 228
chr9_-_128246769 0.131 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr3_+_150264458 0.131 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr3_-_149688655 0.131 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2




profilin 2




chr12_-_96794143 0.126 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr15_-_74501360 0.125 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr13_-_23490508 0.125 ENST00000577004.1
LINC00621
long intergenic non-protein coding RNA 621
chr6_-_88299678 0.124 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr15_-_60695071 0.124 ENST00000557904.1
ANXA2
annexin A2
chr15_+_71839566 0.124 ENST00000357769.4
THSD4
thrombospondin, type I, domain containing 4
chr14_-_101053739 0.123 ENST00000554140.1
BEGAIN
brain-enriched guanylate kinase-associated
chr19_+_13875316 0.123 ENST00000319545.8
ENST00000593245.1
ENST00000040663.6
MRI1


methylthioribose-1-phosphate isomerase 1


chr11_+_4615037 0.123 ENST00000450052.2
OR52I1
olfactory receptor, family 52, subfamily I, member 1
chr6_+_32006159 0.123 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2


cytochrome P450, family 21, subfamily A, polypeptide 2


chr16_+_9056563 0.123 ENST00000564485.1
RP11-77H9.8
RP11-77H9.8
chr12_-_96794330 0.120 ENST00000261211.3
CDK17
cyclin-dependent kinase 17
chr12_+_54402790 0.120 ENST00000040584.4
HOXC8
homeobox C8
chr6_+_155334780 0.117 ENST00000538270.1
ENST00000535231.1
TIAM2

T-cell lymphoma invasion and metastasis 2

chr22_-_30642728 0.117 ENST00000403987.3
LIF
leukemia inhibitory factor
chr15_-_64673630 0.117 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101


KIAA0101


chr1_+_240255166 0.116 ENST00000319653.9
FMN2
formin 2
chr17_+_61571746 0.116 ENST00000579409.1
ACE
angiotensin I converting enzyme
chr5_-_173173171 0.113 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3

CTB-43E15.3

chr14_-_81408093 0.113 ENST00000555265.1
CEP128
centrosomal protein 128kDa
chr16_+_610407 0.112 ENST00000409413.3
C16orf11
chromosome 16 open reading frame 11
chr3_-_146262488 0.111 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr13_+_102104952 0.110 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_74685527 0.108 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WBP1


WW domain binding protein 1


chr22_-_29711645 0.108 ENST00000401450.3
RASL10A
RAS-like, family 10, member A
chr16_+_16472912 0.107 ENST00000530217.2
NPIPA7
nuclear pore complex interacting protein family, member A7
chr2_+_74685413 0.106 ENST00000233615.2
WBP1
WW domain binding protein 1
chr6_-_149867122 0.106 ENST00000253329.2
PPIL4
peptidylprolyl isomerase (cyclophilin)-like 4
chr15_-_64673665 0.106 ENST00000300035.4
KIAA0101
KIAA0101
chr18_-_74207146 0.104 ENST00000443185.2
ZNF516
zinc finger protein 516
chr11_-_111649074 0.102 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr10_-_134756030 0.101 ENST00000368586.5
ENST00000368582.2
TTC40

tetratricopeptide repeat domain 40

chrX_+_37639302 0.101 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr11_+_114166536 0.100 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr10_-_65028938 0.099 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr22_-_22307199 0.098 ENST00000397495.4
ENST00000263212.5
PPM1F

protein phosphatase, Mg2+/Mn2+ dependent, 1F

chr2_-_49381572 0.098 ENST00000454032.1
ENST00000304421.4
FSHR

follicle stimulating hormone receptor

chr19_-_49944806 0.097 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr10_-_65028817 0.097 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr20_+_30467600 0.096 ENST00000375934.4
ENST00000375922.4
TTLL9

tubulin tyrosine ligase-like family, member 9

chr10_+_62538089 0.096 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1


cyclin-dependent kinase 1


chr10_+_62538248 0.095 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr6_+_99282570 0.095 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr1_-_45140074 0.094 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
TMEM53




transmembrane protein 53




chr4_-_38807199 0.094 ENST00000508364.1
TLR1
toll-like receptor 1
chr9_+_33795533 0.093 ENST00000379405.3
PRSS3
protease, serine, 3
chr1_-_182030847 0.090 ENST00000339948.3
ZNF648
zinc finger protein 648
chr17_+_39994032 0.089 ENST00000293303.4
ENST00000438813.1
KLHL10

kelch-like family member 10

chr1_+_226250379 0.089 ENST00000366815.3
ENST00000366814.3
H3F3A

H3 histone, family 3A

chr8_-_119124045 0.089 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr20_+_44036620 0.088 ENST00000372710.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_+_78359999 0.086 ENST00000550503.1
NAV3
neuron navigator 3
chr5_+_162864575 0.085 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1






cyclin G1






chrX_-_154493791 0.085 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr11_-_126870683 0.085 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr10_-_98945264 0.084 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr10_-_102046098 0.084 ENST00000441611.1
BLOC1S2
biogenesis of lysosomal organelles complex-1, subunit 2
chrM_+_4431 0.083 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr17_-_8059638 0.082 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1


period circadian clock 1


chr18_+_11752040 0.082 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr14_-_81408031 0.081 ENST00000216517.6
CEP128
centrosomal protein 128kDa
chr14_-_81408063 0.081 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr5_-_2751762 0.081 ENST00000302057.5
ENST00000382611.6
IRX2

iroquois homeobox 2

chr11_+_61717279 0.080 ENST00000378043.4
BEST1
bestrophin 1
chr3_-_149093499 0.080 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr9_+_35829208 0.080 ENST00000439587.2
ENST00000377991.4
TMEM8B

transmembrane protein 8B

chr1_-_13673511 0.080 ENST00000344998.3
ENST00000334600.6
PRAMEF14

PRAME family member 14

chr1_-_39347255 0.080 ENST00000454994.2
ENST00000357771.3
GJA9

gap junction protein, alpha 9, 59kDa

chr1_-_100643765 0.079 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39


leucine rich repeat containing 39


chr11_+_118754475 0.078 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr5_-_20575959 0.078 ENST00000507958.1
CDH18
cadherin 18, type 2
chr20_+_44036900 0.077 ENST00000443296.1
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_+_5681153 0.077 ENST00000577222.1
ENST00000579559.1
RPL36
HSD11B1L
ribosomal protein L36
hydroxysteroid (11-beta) dehydrogenase 1-like
chr20_-_30458432 0.077 ENST00000375966.4
ENST00000278979.3
DUSP15

dual specificity phosphatase 15

chr19_-_18654828 0.076 ENST00000609656.1
ENST00000597611.3
FKBP8

FK506 binding protein 8, 38kDa

chr19_-_50266580 0.076 ENST00000246801.3
TSKS
testis-specific serine kinase substrate
chr7_+_20370746 0.074 ENST00000222573.4
ITGB8
integrin, beta 8
chr12_+_10658489 0.074 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr15_-_81666546 0.074 ENST00000558726.1
ENST00000359440.5
TMC3

transmembrane channel-like 3

chr11_-_116643688 0.074 ENST00000375445.3
ENST00000260210.4
BUD13

BUD13 homolog (S. cerevisiae)

chr12_-_88423164 0.073 ENST00000298699.2
ENST00000550553.1
C12orf50

chromosome 12 open reading frame 50

chr13_-_52026730 0.072 ENST00000420668.2
INTS6
integrator complex subunit 6
chr10_-_98945677 0.072 ENST00000266058.4
ENST00000371041.3
SLIT1

slit homolog 1 (Drosophila)

chr1_-_151319710 0.071 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5




regulatory factor X, 5 (influences HLA class II expression)




chr16_-_9030515 0.071 ENST00000535863.1
ENST00000381886.4
USP7

ubiquitin specific peptidase 7 (herpes virus-associated)

chr3_+_130150307 0.071 ENST00000512836.1
COL6A5
collagen, type VI, alpha 5
chr12_-_101604185 0.070 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr13_+_28519343 0.070 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr13_+_113863858 0.069 ENST00000375440.4
CUL4A
cullin 4A
chr15_-_75134992 0.069 ENST00000568667.1
ULK3
unc-51 like kinase 3
chr9_+_132962843 0.069 ENST00000458469.1
NCS1
neuronal calcium sensor 1
chr10_+_98741041 0.068 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr10_+_99349450 0.068 ENST00000370640.3
C10orf62
chromosome 10 open reading frame 62
chr1_+_85527987 0.068 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63


WD repeat domain 63


chr8_-_37411648 0.067 ENST00000519738.1
RP11-150O12.1
RP11-150O12.1
chr11_-_72070206 0.066 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr15_+_84908573 0.066 ENST00000424966.1
ENST00000422563.2
GOLGA6L4

golgin A6 family-like 4

chr10_-_9801179 0.065 ENST00000419836.1
RP5-1051H14.2
RP5-1051H14.2
chr10_-_29923893 0.065 ENST00000355867.4
SVIL
supervillin
chr2_+_1488435 0.065 ENST00000446278.1
ENST00000469607.1
TPO

thyroid peroxidase

chr2_-_49381646 0.065 ENST00000346173.3
ENST00000406846.2
FSHR

follicle stimulating hormone receptor

chr19_-_11450249 0.064 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr22_-_41677625 0.064 ENST00000452543.1
ENST00000418067.1
RANGAP1

Ran GTPase activating protein 1

chr12_-_129570545 0.064 ENST00000389441.4
TMEM132D
transmembrane protein 132D
chr21_-_32119551 0.063 ENST00000333892.2
KRTAP21-2
keratin associated protein 21-2
chr5_-_78365437 0.061 ENST00000380311.4
ENST00000540686.1
ENST00000255189.3
DMGDH


dimethylglycine dehydrogenase


chr15_+_67418047 0.060 ENST00000540846.2
SMAD3
SMAD family member 3
chr7_-_137028534 0.060 ENST00000348225.2
PTN
pleiotrophin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.5 1.6 GO:0050894 determination of affect(GO:0050894)
0.3 1.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 0.7 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.8 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.5 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.3 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.2 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 0.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.3 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0060708 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 1.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.3 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0042245 RNA repair(GO:0042245)
0.0 0.3 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.0 GO:0071262 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0 0.1 GO:0010911 phosphatidylserine biosynthetic process(GO:0006659) regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 1.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.1 2.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects