Motif ID: HNF4G

Z-value: 0.522


Transcription factors associated with HNF4G:

Gene SymbolEntrez IDGene Name
HNF4G ENSG00000164749.7 HNF4G

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HNF4Ghg19_v2_chr8_+_76452097_76452126-0.491.8e-01Click!


Activity profile for motif HNF4G.

activity profile for motif HNF4G


Sorted Z-values histogram for motif HNF4G

Sorted Z-values for motif HNF4G



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF4G

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_47286729 0.555 ENST00000300406.2
ENST00000511277.1
ENST00000511673.1
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr12_-_55367361 0.488 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1


thymocyte expressed, positive selection associated 1


chr12_-_55367331 0.395 ENST00000526532.1
ENST00000532757.1
TESPA1

thymocyte expressed, positive selection associated 1

chr16_-_3493528 0.386 ENST00000301744.4
ZNF597
zinc finger protein 597
chr17_+_47287749 0.371 ENST00000419580.2
ABI3
ABI family, member 3
chr6_-_130182410 0.358 ENST00000368143.1
TMEM244
transmembrane protein 244
chr4_-_6383594 0.323 ENST00000335585.5
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr6_+_160693591 0.313 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr1_+_2407754 0.307 ENST00000419816.2
ENST00000378486.3
ENST00000378488.3
ENST00000288766.5
PLCH2



phospholipase C, eta 2



chr22_-_37880543 0.297 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_+_2746850 0.284 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2


glycogenin 2


chr20_-_7921090 0.273 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chrX_+_2746818 0.264 ENST00000398806.3
GYG2
glycogenin 2
chr9_+_139839686 0.239 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr17_+_4337199 0.237 ENST00000333476.2
SPNS3
spinster homolog 3 (Drosophila)
chr9_-_117568365 0.224 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr5_+_176237478 0.215 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr3_+_157261116 0.206 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55




chromosome 3 open reading frame 55




chr9_-_79307096 0.203 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2


prune homolog 2 (Drosophila)


chr12_-_2027639 0.200 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4


calcium channel, voltage-dependent, alpha 2/delta subunit 4


chr3_+_157261035 0.200 ENST00000312275.5
C3orf55
chromosome 3 open reading frame 55
chr2_-_74782817 0.199 ENST00000413469.1
LOXL3
lysyl oxidase-like 3
chr17_-_17740325 0.192 ENST00000338854.5
SREBF1
sterol regulatory element binding transcription factor 1
chr3_+_124355944 0.189 ENST00000459915.1
KALRN
kalirin, RhoGEF kinase
chr12_-_95009837 0.188 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr19_-_55686399 0.187 ENST00000587067.1
SYT5
synaptotagmin V
chr11_-_118135160 0.185 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr17_-_17740287 0.184 ENST00000355815.4
ENST00000261646.5
SREBF1

sterol regulatory element binding transcription factor 1

chr17_-_7082861 0.180 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr14_+_69726656 0.177 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr2_+_242750274 0.177 ENST00000405370.1
NEU4
sialidase 4
chr12_-_95010147 0.172 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr11_-_66496655 0.172 ENST00000527010.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr12_+_6949964 0.167 ENST00000541978.1
ENST00000435982.2
GNB3

guanine nucleotide binding protein (G protein), beta polypeptide 3

chr12_+_54422142 0.163 ENST00000243108.4
HOXC6
homeobox C6
chr20_+_62669472 0.163 ENST00000463337.1
ENST00000358393.1
LINC00176

long intergenic non-protein coding RNA 176

chr19_+_1041212 0.157 ENST00000433129.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr5_+_159656437 0.156 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr14_-_103589246 0.155 ENST00000558224.1
ENST00000560742.1
LINC00677

long intergenic non-protein coding RNA 677

chr20_-_32308028 0.154 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4


peroxisomal membrane protein 4, 24kDa


chr16_+_25228242 0.154 ENST00000219660.5
AQP8
aquaporin 8
chr12_-_75723805 0.151 ENST00000409799.1
ENST00000409445.3
CAPS2

calcyphosine 2

chr13_+_27131887 0.151 ENST00000335327.5
WASF3
WAS protein family, member 3
chr11_-_118134997 0.149 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr2_-_43019698 0.149 ENST00000431905.1
ENST00000294973.6
HAAO

3-hydroxyanthranilate 3,4-dioxygenase

chr1_-_177939348 0.145 ENST00000464631.2
SEC16B
SEC16 homolog B (S. cerevisiae)
chr19_-_6720686 0.145 ENST00000245907.6
C3
complement component 3
chr14_+_100070869 0.145 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr17_+_61562201 0.144 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
ACE


angiotensin I converting enzyme


chrX_+_100646190 0.139 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr22_+_19950060 0.137 ENST00000449653.1
COMT
catechol-O-methyltransferase
chr11_-_66496430 0.135 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr16_-_87970122 0.135 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr16_+_3115378 0.133 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
IL32




interleukin 32




chr14_+_37131058 0.133 ENST00000361487.6
PAX9
paired box 9
chr20_-_56265680 0.132 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_+_53686658 0.131 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr15_-_72668805 0.130 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr18_-_53253112 0.130 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chrX_+_100645812 0.128 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A


RPL36A-HNRNPH2

ribosomal protein L36a


RPL36A-HNRNPH2 readthrough

chr1_-_6550625 0.127 ENST00000377725.1
ENST00000340850.5
PLEKHG5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5

chr9_+_130890612 0.127 ENST00000443493.1
AL590708.2
AL590708.2
chr1_+_45274154 0.124 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19


BTB (POZ) domain containing 19


chr16_+_66637777 0.123 ENST00000563672.1
ENST00000424011.2
CMTM3

CKLF-like MARVEL transmembrane domain containing 3

chr1_-_177939041 0.122 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr3_-_126236605 0.121 ENST00000290868.2
UROC1
urocanate hydratase 1
chr8_-_98290087 0.121 ENST00000322128.3
TSPYL5
TSPY-like 5
chr16_-_67450325 0.121 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr1_+_156785425 0.120 ENST00000392302.2
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr7_-_44122063 0.120 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM




polymerase (DNA directed), mu




chr2_-_61389168 0.119 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1

RP11-493E12.1

chr9_+_129097520 0.116 ENST00000436593.3
MVB12B
multivesicular body subunit 12B
chr10_+_118187379 0.116 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr19_+_42381173 0.116 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr1_+_16084428 0.112 ENST00000510929.1
ENST00000502638.1
FBLIM1

filamin binding LIM protein 1

chr5_+_135383008 0.112 ENST00000508767.1
ENST00000604555.1
TGFBI

transforming growth factor, beta-induced, 68kDa

chr19_+_926000 0.111 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr18_-_53253323 0.109 ENST00000540999.1
ENST00000563888.2
TCF4

transcription factor 4

chr1_+_153600869 0.109 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1


S100 calcium binding protein A1


chr3_+_119501557 0.109 ENST00000337940.4
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr12_+_58013693 0.105 ENST00000320442.4
ENST00000379218.2
SLC26A10

solute carrier family 26, member 10

chr12_-_48963829 0.105 ENST00000301046.2
ENST00000549817.1
LALBA

lactalbumin, alpha-

chr2_-_237416071 0.104 ENST00000309507.5
ENST00000431676.2
IQCA1

IQ motif containing with AAA domain 1

chr16_+_2880157 0.102 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr2_-_70475730 0.102 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1


TIA1 cytotoxic granule-associated RNA binding protein


chr6_+_12008986 0.101 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr17_-_17494972 0.101 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
PEMT


phosphatidylethanolamine N-methyltransferase


chr3_+_122785895 0.100 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr22_+_45072925 0.100 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr1_+_27668505 0.099 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr2_-_70475701 0.099 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr1_-_31196427 0.099 ENST00000373765.4
MATN1
matrilin 1, cartilage matrix protein
chr19_-_11308190 0.099 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2




KN motif and ankyrin repeat domains 2




chr22_-_42526802 0.099 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
CYP2D6


cytochrome P450, family 2, subfamily D, polypeptide 6


chr1_+_26348259 0.098 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr22_+_21321447 0.097 ENST00000434714.1
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr11_-_65325430 0.095 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr22_+_42229100 0.094 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr2_+_85198216 0.093 ENST00000456682.1
ENST00000409785.4
KCMF1

potassium channel modulatory factor 1

chr19_-_5785630 0.093 ENST00000590343.1
ENST00000586012.1
DUS3L
CTB-54O9.9
dihydrouridine synthase 3-like (S. cerevisiae)
Uncharacterized protein
chr7_-_84122033 0.093 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_6557463 0.093 ENST00000544978.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_-_85473156 0.093 ENST00000606784.1
ENST00000606325.1
TBX18

T-box 18

chr21_+_47013566 0.092 ENST00000441095.1
ENST00000424569.1
AL133493.2

AL133493.2

chr10_+_96443204 0.092 ENST00000339022.5
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr2_+_113670548 0.091 ENST00000263326.3
ENST00000352179.3
ENST00000349806.3
ENST00000353225.3
IL37



interleukin 37



chr12_+_20963632 0.091 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr4_-_186682716 0.090 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr19_+_41594377 0.090 ENST00000330436.3
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr19_+_49547099 0.088 ENST00000301408.6
CGB5
chorionic gonadotropin, beta polypeptide 5
chr3_-_126236588 0.088 ENST00000383579.3
UROC1
urocanate hydratase 1
chr6_-_33771757 0.088 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN


motilin


chr16_+_3115611 0.087 ENST00000530890.1
ENST00000444393.3
ENST00000533097.2
ENST00000008180.9
ENST00000396890.2
ENST00000525228.1
ENST00000548652.1
ENST00000525377.2
ENST00000530538.2
ENST00000549213.1
ENST00000552936.1
ENST00000548476.1
ENST00000552664.1
ENST00000552356.1
ENST00000551513.1
ENST00000382213.3
ENST00000548246.1
IL32
















interleukin 32
















chr9_+_126131131 0.087 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr12_+_20963647 0.087 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr22_+_24115000 0.084 ENST00000215743.3
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr3_-_48471454 0.084 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr1_-_20250110 0.083 ENST00000375116.3
PLA2G2E
phospholipase A2, group IIE
chr10_-_79398250 0.083 ENST00000286627.5
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_+_129987488 0.083 ENST00000446764.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr17_-_2117600 0.083 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr2_-_85108164 0.083 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr21_+_42688657 0.083 ENST00000357985.2
FAM3B
family with sequence similarity 3, member B
chr16_+_3115298 0.081 ENST00000325568.5
ENST00000534507.1
IL32

interleukin 32

chr2_-_70475586 0.079 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr8_+_21911054 0.079 ENST00000519850.1
ENST00000381470.3
DMTN

dematin actin binding protein

chr19_+_51728316 0.077 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33



CD33 molecule



chr5_-_43313574 0.077 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr5_+_157602404 0.077 ENST00000522975.1
CTC-436K13.1
CTC-436K13.1
chr2_+_242750160 0.076 ENST00000415936.1
NEU4
sialidase 4
chr13_-_53313905 0.076 ENST00000377962.3
ENST00000448904.2
LECT1

leukocyte cell derived chemotaxin 1

chr22_-_37415475 0.076 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
TST


thiosulfate sulfurtransferase (rhodanese)


chr2_+_242750321 0.075 ENST00000423583.1
NEU4
sialidase 4
chr16_+_2880254 0.074 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr17_-_7082668 0.074 ENST00000573083.1
ENST00000574388.1
ASGR1

asialoglycoprotein receptor 1

chr20_-_36794902 0.073 ENST00000373403.3
TGM2
transglutaminase 2
chr1_+_113263199 0.073 ENST00000361886.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr7_-_84121858 0.073 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_171810650 0.073 ENST00000520906.1
DNM3
dynamin 3
chr8_-_145642267 0.072 ENST00000301305.3
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr12_+_121416489 0.072 ENST00000541395.1
ENST00000544413.1
HNF1A

HNF1 homeobox A

chr17_-_18585541 0.072 ENST00000285274.5
ENST00000545289.1
ENST00000580145.1
ZNF286B


zinc finger protein 286B


chr9_-_136605042 0.072 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
SARDH


sarcosine dehydrogenase


chr2_-_65593784 0.071 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr11_+_13299186 0.070 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL












aryl hydrocarbon receptor nuclear translocator-like












chr19_+_46003056 0.070 ENST00000401593.1
ENST00000396736.2
PPM1N

protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)

chr21_-_45627282 0.070 ENST00000423967.1
AP001058.3
AP001058.3
chr22_-_29711645 0.070 ENST00000401450.3
RASL10A
RAS-like, family 10, member A
chr20_-_36794938 0.070 ENST00000453095.1
TGM2
transglutaminase 2
chr15_+_89010923 0.070 ENST00000353598.6
MRPS11
mitochondrial ribosomal protein S11
chr1_-_38397384 0.069 ENST00000373027.1
INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr12_+_57854274 0.069 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr8_-_37189432 0.068 ENST00000518765.1
RP11-527N22.1
RP11-527N22.1
chr11_-_61596753 0.067 ENST00000448607.1
ENST00000421879.1
FADS1

fatty acid desaturase 1

chr11_+_1855645 0.067 ENST00000381968.3
ENST00000381978.3
SYT8

synaptotagmin VIII

chr11_+_98891797 0.066 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
CNTN5


contactin 5


chr16_+_3115323 0.066 ENST00000531965.1
ENST00000396887.3
ENST00000529699.1
ENST00000526464.2
ENST00000440815.3
IL32




interleukin 32




chr12_+_3068957 0.066 ENST00000543035.1
TEAD4
TEA domain family member 4
chr20_-_30458354 0.066 ENST00000428829.1
DUSP15
dual specificity phosphatase 15
chr13_+_43597269 0.065 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr9_-_125391852 0.065 ENST00000304833.3
OR1B1
olfactory receptor, family 1, subfamily B, member 1
chr19_+_37837218 0.065 ENST00000591134.1
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr10_+_69865866 0.065 ENST00000354393.2
MYPN
myopalladin
chr10_+_102222798 0.065 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr12_+_54519842 0.064 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chrX_-_52683950 0.064 ENST00000298181.5
SSX7
synovial sarcoma, X breakpoint 7
chr15_-_89010607 0.064 ENST00000312475.4
MRPL46
mitochondrial ribosomal protein L46
chr9_+_129097479 0.064 ENST00000402437.2
MVB12B
multivesicular body subunit 12B
chr1_+_210502238 0.064 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
HHAT





hedgehog acyltransferase





chr11_+_67071050 0.063 ENST00000376757.5
SSH3
slingshot protein phosphatase 3
chr6_-_41006928 0.063 ENST00000244565.3
UNC5CL
unc-5 homolog C (C. elegans)-like
chr2_+_241807870 0.063 ENST00000307503.3
AGXT
alanine-glyoxylate aminotransferase
chr3_+_53195517 0.063 ENST00000487897.1
PRKCD
protein kinase C, delta
chr11_+_1856034 0.062 ENST00000341958.3
SYT8
synaptotagmin VIII
chr11_+_66115304 0.061 ENST00000531602.1
RP11-867G23.8
Uncharacterized protein
chr8_-_145641864 0.061 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_-_41131326 0.061 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr10_-_114206649 0.061 ENST00000369404.3
ENST00000369405.3
ZDHHC6

zinc finger, DHHC-type containing 6

chr16_+_84209738 0.061 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr17_+_27369918 0.061 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr19_-_19373601 0.060 ENST00000291481.7
HAPLN4
hyaluronan and proteoglycan link protein 4
chr4_-_171011084 0.060 ENST00000337664.4
AADAT
aminoadipate aminotransferase
chr4_-_171011323 0.060 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
AADAT



aminoadipate aminotransferase



chr9_+_139221880 0.060 ENST00000392945.3
ENST00000440944.1
GPSM1

G-protein signaling modulator 1

chr10_-_17171817 0.060 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr11_-_65381643 0.060 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11


mitogen-activated protein kinase kinase kinase 11


chr19_+_10196981 0.060 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr8_+_133931648 0.059 ENST00000519178.1
ENST00000542445.1
TG

thyroglobulin

chr6_+_131894284 0.059 ENST00000368087.3
ENST00000356962.2
ARG1

arginase 1

chr4_-_7436671 0.058 ENST00000319098.4
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr19_-_3480540 0.058 ENST00000215531.4
C19orf77
chromosome 19 open reading frame 77
chr19_-_41356347 0.058 ENST00000301141.5
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr11_+_18417813 0.058 ENST00000540430.1
ENST00000379412.5
LDHA

lactate dehydrogenase A

chr17_+_48624450 0.057 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20


spermatogenesis associated 20


chr14_-_55738788 0.057 ENST00000556183.1
RP11-665C16.6
RP11-665C16.6
chr6_+_108977520 0.056 ENST00000540898.1
FOXO3
forkhead box O3
chrX_-_153599578 0.056 ENST00000360319.4
ENST00000344736.4
FLNA

filamin A, alpha

chr16_+_67552303 0.056 ENST00000562116.1
FAM65A
family with sequence similarity 65, member A
chr10_+_96443378 0.056 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr19_-_51017127 0.056 ENST00000389208.4
ASPDH
aspartate dehydrogenase domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.2 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.0 0.1 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.2 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.4 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.0 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.0 0.0 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.0 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.0 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.0 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.0 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.0 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.2 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 0.1 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.1 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.2 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.0 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.0 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism