Motif ID: HNF1A_HNF1B

Z-value: 0.616

Transcription factors associated with HNF1A_HNF1B:

Gene SymbolEntrez IDGene Name
HNF1A ENSG00000135100.13 HNF1A
HNF1B ENSG00000108753.8 HNF1B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HNF1Ahg19_v2_chr12_+_121416489_121416552-0.521.5e-01Click!
HNF1Bhg19_v2_chr17_-_36105009_361050600.156.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_27719697 1.182 ENST00000264717.2
ENST00000424318.2
GCKR

glucokinase (hexokinase 4) regulator

chr1_+_207262170 0.775 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr10_+_5135981 0.729 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr14_-_54425475 0.711 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr1_+_207262578 0.582 ENST00000243611.5
ENST00000367076.3
C4BPB

complement component 4 binding protein, beta

chrX_-_15683147 0.572 ENST00000380342.3
TMEM27
transmembrane protein 27
chr4_+_74301880 0.570 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr1_+_207262627 0.524 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr1_-_204183071 0.486 ENST00000308302.3
GOLT1A
golgi transport 1A
chr10_-_61495760 0.418 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr4_+_169013666 0.402 ENST00000359299.3
ANXA10
annexin A10
chr7_+_141695671 0.385 ENST00000497673.1
ENST00000475668.2
MGAM

maltase-glucoamylase (alpha-glucosidase)

chr4_-_110723134 0.381 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr3_+_187930491 0.373 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_187930429 0.350 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr14_-_57960456 0.339 ENST00000534126.1
ENST00000422976.2
C14orf105

chromosome 14 open reading frame 105

chr4_-_109541610 0.337 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr7_+_141695633 0.335 ENST00000549489.2
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr4_-_110723194 0.334 ENST00000394635.3
CFI
complement factor I
chr4_-_110723335 0.325 ENST00000394634.2
CFI
complement factor I
chr5_-_35195338 0.323 ENST00000509839.1
PRLR
prolactin receptor
chr2_+_182850551 0.293 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr17_-_202579 0.292 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL


rabphilin 3A-like (without C2 domains)


chr19_+_11350278 0.288 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr7_-_104567066 0.283 ENST00000453666.1
RP11-325F22.5
RP11-325F22.5
chr8_-_70745575 0.265 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr2_+_182850743 0.257 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_-_197036364 0.253 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr6_+_161123270 0.232 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr2_-_162931052 0.224 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr10_-_128359074 0.210 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr6_+_126070726 0.205 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr4_+_3443614 0.200 ENST00000382774.3
ENST00000511533.1
HGFAC

HGF activator

chr22_-_38506619 0.198 ENST00000332536.5
ENST00000381669.3
BAIAP2L2

BAI1-associated protein 2-like 2

chr12_-_15865844 0.195 ENST00000543612.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr6_-_154751629 0.186 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr9_-_116861337 0.174 ENST00000374118.3
KIF12
kinesin family member 12
chr3_+_183948161 0.170 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr4_-_1166954 0.170 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
SPON2


spondin 2, extracellular matrix protein


chr2_+_38177575 0.166 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2



regulator of microtubule dynamics 2



chr6_+_126221034 0.166 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr5_+_125706998 0.157 ENST00000506445.1
GRAMD3
GRAM domain containing 3
chr4_+_14113592 0.150 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085



long intergenic non-protein coding RNA 1085



chr8_-_120685608 0.147 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_+_45927956 0.146 ENST00000275525.3
ENST00000457280.1
IGFBP1

insulin-like growth factor binding protein 1

chr3_-_161089289 0.146 ENST00000497137.1
SPTSSB
serine palmitoyltransferase, small subunit B
chr12_-_24102576 0.145 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
SOX5



SRY (sex determining region Y)-box 5



chr4_-_987217 0.144 ENST00000361661.2
ENST00000398516.2
SLC26A1

solute carrier family 26 (anion exchanger), member 1

chr3_+_75955817 0.141 ENST00000487694.3
ENST00000602589.1
ROBO2

roundabout, axon guidance receptor, homolog 2 (Drosophila)

chr5_+_140571902 0.140 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr11_-_111649074 0.136 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr16_-_20587599 0.135 ENST00000566384.1
ENST00000565232.1
ENST00000567001.1
ENST00000565322.1
ENST00000569344.1
ENST00000329697.6
ENST00000414188.2
ENST00000568882.1
ACSM2B







acyl-CoA synthetase medium-chain family member 2B







chr7_+_45928079 0.133 ENST00000468955.1
IGFBP1
insulin-like growth factor binding protein 1
chr4_-_76944621 0.130 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr4_+_155484155 0.129 ENST00000509493.1
FGB
fibrinogen beta chain
chr1_+_207262881 0.125 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr1_+_104159999 0.120 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr15_+_26360970 0.117 ENST00000556159.1
ENST00000557523.1
LINC00929

long intergenic non-protein coding RNA 929

chr16_+_20775358 0.117 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr12_+_60058458 0.115 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr17_+_35732916 0.115 ENST00000586700.1
C17orf78
chromosome 17 open reading frame 78
chr4_+_108815402 0.115 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr11_-_111649015 0.114 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr4_+_155484103 0.114 ENST00000302068.4
FGB
fibrinogen beta chain
chr8_-_95220775 0.113 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17


cadherin 17, LI cadherin (liver-intestine)


chr2_+_28718921 0.110 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1


phospholipase B1


chr5_-_59668541 0.106 ENST00000514552.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_39703084 0.106 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr17_+_35732955 0.105 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr1_+_36789335 0.105 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr1_-_229406746 0.105 ENST00000429227.1
ENST00000436334.1
RP5-1061H20.4

RP5-1061H20.4

chr17_-_26733604 0.099 ENST00000584426.1
ENST00000584995.1
SLC46A1

solute carrier family 46 (folate transporter), member 1

chr20_+_42187682 0.099 ENST00000373092.3
ENST00000373077.1
SGK2

serum/glucocorticoid regulated kinase 2

chr9_+_140125385 0.097 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr5_+_67586465 0.095 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_+_135340859 0.091 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1


cytochrome P450, family 2, subfamily E, polypeptide 1


chr7_-_115608304 0.085 ENST00000457268.1
TFEC
transcription factor EC
chr4_-_987164 0.081 ENST00000398520.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr9_-_215744 0.077 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr12_-_39837192 0.077 ENST00000361961.3
ENST00000395670.3
KIF21A

kinesin family member 21A

chr14_+_38033252 0.077 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr4_+_100495864 0.075 ENST00000265517.5
ENST00000422897.2
MTTP

microsomal triglyceride transfer protein

chr9_+_140125209 0.074 ENST00000538474.1
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr19_+_29097595 0.074 ENST00000587961.1
AC079466.1
AC079466.1
chr16_+_22524379 0.073 ENST00000536620.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr4_+_74269956 0.069 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB




albumin




chr1_-_207206092 0.068 ENST00000359470.5
ENST00000461135.2
C1orf116

chromosome 1 open reading frame 116

chr17_-_26733179 0.068 ENST00000440501.1
ENST00000321666.5
SLC46A1

solute carrier family 46 (folate transporter), member 1

chr8_+_20054878 0.067 ENST00000276390.2
ENST00000519667.1
ATP6V1B2

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

chr3_+_180319918 0.066 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
TTC14



tetratricopeptide repeat domain 14



chr4_+_8201091 0.066 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1



SH3 domain and tetratricopeptide repeats 1



chr18_-_2982869 0.066 ENST00000584915.1
LPIN2
lipin 2
chr1_+_63063152 0.062 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr15_-_42343388 0.062 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE
chr20_+_42187608 0.058 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr6_-_33754778 0.055 ENST00000508327.1
ENST00000513701.1
LEMD2

LEM domain containing 2

chr16_-_75284758 0.055 ENST00000561970.1
BCAR1
breast cancer anti-estrogen resistance 1
chr4_-_74486217 0.054 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr12_+_70132632 0.054 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3IP


RAB3A interacting protein


chr18_-_70931689 0.052 ENST00000581862.1
RP11-169F17.1
Protein LOC400655
chr1_-_168464875 0.051 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr4_-_74486109 0.051 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chrX_-_15619076 0.050 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr16_+_20911174 0.050 ENST00000568663.1
LYRM1
LYR motif containing 1
chr12_+_80838126 0.047 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr5_-_138718973 0.044 ENST00000353963.3
ENST00000348729.3
SLC23A1

solute carrier family 23 (ascorbic acid transporter), member 1

chr22_-_30968839 0.044 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1




galactose-3-O-sulfotransferase 1




chr12_-_18243075 0.043 ENST00000536890.1
RERGL
RERG/RAS-like
chr11_+_560956 0.043 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
RASSF7


Ras association (RalGDS/AF-6) domain family (N-terminal) member 7


chr17_-_36904437 0.043 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2



polycomb group ring finger 2



chr3_+_185431080 0.042 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr4_-_22444733 0.041 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr12_-_91546926 0.041 ENST00000550758.1
DCN
decorin
chr6_+_54172653 0.041 ENST00000370869.3
TINAG
tubulointerstitial nephritis antigen
chrX_+_1710484 0.040 ENST00000313871.3
ENST00000381261.3
AKAP17A

A kinase (PRKA) anchor protein 17A

chr4_+_39408470 0.039 ENST00000257408.4
KLB
klotho beta
chr7_-_44580861 0.037 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1



NPC1-like 1



chr2_-_158300556 0.037 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr4_+_71494461 0.036 ENST00000396073.3
ENAM
enamelin
chr16_+_21244986 0.036 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr14_-_94759595 0.035 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_177796841 0.035 ENST00000508790.1
RP11-765K14.1
RP11-765K14.1
chr6_+_31707725 0.034 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5






mutS homolog 5






chr10_+_99344071 0.034 ENST00000370647.4
ENST00000370646.4
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr12_-_56615485 0.034 ENST00000549038.1
ENST00000552244.1
RNF41

ring finger protein 41

chr14_-_94759408 0.034 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_-_166034029 0.033 ENST00000306480.6
TMEM192
transmembrane protein 192
chr1_-_36020531 0.033 ENST00000440579.1
ENST00000494948.1
KIAA0319L

KIAA0319-like

chr1_+_55505184 0.033 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chrX_+_48660107 0.033 ENST00000376643.2
HDAC6
histone deacetylase 6
chr14_-_94759361 0.029 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr17_+_41363854 0.029 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A




transmembrane protein 106A




chr12_-_56615693 0.028 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
RNF41



ring finger protein 41



chr5_+_40841410 0.028 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr7_-_50633078 0.028 ENST00000444124.2
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr17_+_1646130 0.028 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2




serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2




chr1_+_104293028 0.027 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr4_-_74486347 0.027 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr3_-_196911002 0.026 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr5_-_139726181 0.026 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr6_-_133084580 0.026 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2


vanin 2


chr10_-_52645416 0.025 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF





APOBEC1 complementation factor





chr7_+_152456829 0.025 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B


ARP3 actin-related protein 3 homolog B (yeast)


chr17_+_41052808 0.025 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC


glucose-6-phosphatase, catalytic subunit


chr7_-_150020814 0.024 ENST00000477871.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr5_-_77844974 0.024 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr9_-_13165457 0.024 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr18_-_48346415 0.023 ENST00000431965.2
ENST00000436348.2
MRO

maestro

chr19_-_43099070 0.023 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr12_+_70133152 0.023 ENST00000550536.1
ENST00000362025.5
RAB3IP

RAB3A interacting protein

chr12_+_25205568 0.022 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr15_+_48498480 0.021 ENST00000380993.3
ENST00000396577.3
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporter), member 1

chr5_+_40841276 0.021 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr11_-_107729887 0.020 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr7_-_150020578 0.020 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr14_+_39703112 0.019 ENST00000555143.1
ENST00000280082.3
MIA2

melanoma inhibitory activity 2

chr19_-_38916839 0.018 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4




RAS guanyl releasing protein 4




chr1_+_162351503 0.017 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr6_-_117747015 0.017 ENST00000368508.3
ENST00000368507.3
ROS1

c-ros oncogene 1 , receptor tyrosine kinase

chr7_+_152456904 0.016 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr7_-_47579188 0.016 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3



tensin 3



chr10_-_72648541 0.014 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr7_-_6098770 0.014 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
EIF2AK1


eukaryotic translation initiation factor 2-alpha kinase 1


chr8_-_124749609 0.013 ENST00000262219.6
ENST00000419625.1
ANXA13

annexin A13

chr5_+_1225470 0.013 ENST00000324642.3
ENST00000296821.4
SLC6A18

solute carrier family 6 (neutral amino acid transporter), member 18

chr6_+_144665237 0.012 ENST00000421035.2
UTRN
utrophin
chr4_+_124571409 0.012 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1


long intergenic non-protein coding RNA 1091


chr2_+_234668894 0.011 ENST00000608383.1
ENST00000360418.3
ENST00000305208.5
UGT1A1

UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8

UDP glucuronosyltransferase 1 family, polypeptide A1
chr2_+_191792376 0.011 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr7_-_47578840 0.011 ENST00000450444.1
TNS3
tensin 3
chr2_-_87248975 0.011 ENST00000409310.2
ENST00000355705.3
PLGLB1

plasminogen-like B1

chr3_+_107318157 0.011 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr3_+_186383741 0.010 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr12_-_102874378 0.009 ENST00000456098.1
IGF1
insulin-like growth factor 1 (somatomedin C)
chr11_-_26743546 0.009 ENST00000280467.6
ENST00000396005.3
SLC5A12

solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12

chr2_+_133174147 0.009 ENST00000329321.3
GPR39
G protein-coupled receptor 39
chr7_-_122840015 0.008 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr19_+_41305085 0.008 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr13_-_103719196 0.007 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr4_-_102267953 0.006 ENST00000523694.2
ENST00000507176.1
PPP3CA

protein phosphatase 3, catalytic subunit, alpha isozyme

chr1_+_207277590 0.006 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr1_-_110284384 0.005 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr2_+_38177620 0.004 ENST00000402091.3
RMDN2
regulator of microtubule dynamics 2
chr3_+_38307313 0.004 ENST00000450935.2
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr1_+_205197304 0.004 ENST00000358024.3
TMCC2
transmembrane and coiled-coil domain family 2
chr19_+_39138320 0.004 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4


actinin, alpha 4


chr10_-_75193308 0.004 ENST00000299432.2
MSS51
MSS51 mitochondrial translational activator
chr1_+_104198640 0.003 ENST00000422549.1
AMY1A
amylase, alpha 1A (salivary)
chr12_-_102874416 0.003 ENST00000392904.1
ENST00000337514.6
IGF1

insulin-like growth factor 1 (somatomedin C)

chr2_+_109223595 0.003 ENST00000410093.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_-_116833500 0.002 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr19_-_44171817 0.002 ENST00000593714.1
PLAUR
plasminogen activator, urokinase receptor
chr7_-_150020750 0.002 ENST00000539352.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr3_-_126327398 0.002 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr11_-_107729287 0.001 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr5_+_140772381 0.001 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr12_+_25205628 0.001 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr9_+_22646189 0.000 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr22_-_22337154 0.000 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B






topoisomerase (DNA) III beta







Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.2 2.0 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2 1.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.7 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.8 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0045550 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.2 1.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.8 GO:0016160 amylase activity(GO:0016160)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0005135 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 1.2 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling