Motif ID: HIVEP1

Z-value: 0.732


Transcription factors associated with HIVEP1:

Gene SymbolEntrez IDGene Name
HIVEP1 ENSG00000095951.12 HIVEP1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HIVEP1hg19_v2_chr6_+_12008986_120090160.872.6e-03Click!


Activity profile for motif HIVEP1.

activity profile for motif HIVEP1


Sorted Z-values histogram for motif HIVEP1

Sorted Z-values for motif HIVEP1



Network of associatons between targets according to the STRING database.



First level regulatory network of HIVEP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_74120094 1.203 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2




actin, gamma 2, smooth muscle, enteric




chr13_-_46756351 1.151 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_55367361 1.071 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1


thymocyte expressed, positive selection associated 1


chrX_-_138304939 0.905 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr12_-_55367331 0.836 ENST00000526532.1
ENST00000532757.1
TESPA1

thymocyte expressed, positive selection associated 1

chr12_-_55375622 0.633 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr1_+_156611704 0.595 ENST00000329117.5
BCAN
brevican
chr19_+_4229495 0.556 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr1_+_156611900 0.548 ENST00000457777.2
ENST00000424639.1
BCAN

brevican

chr14_+_52313833 0.468 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr17_-_41984835 0.466 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
MPP2







membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)







chr17_-_46623441 0.459 ENST00000330070.4
HOXB2
homeobox B2
chr11_-_124767693 0.401 ENST00000533054.1
ROBO4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr17_-_41985096 0.384 ENST00000269095.4
ENST00000523220.1
MPP2

membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)

chr20_+_31499459 0.378 ENST00000439060.1
EFCAB8
EF-hand calcium binding domain 8
chr2_-_227050079 0.377 ENST00000423838.1
AC068138.1
AC068138.1
chr4_-_74864386 0.357 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_+_156611960 0.346 ENST00000361588.5
BCAN
brevican
chr1_+_114522049 0.331 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chr15_-_74659978 0.329 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1


cytochrome P450, family 11, subfamily A, polypeptide 1


chr7_+_144015218 0.323 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr7_+_6713376 0.319 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1


Uncharacterized protein


chr3_-_111852128 0.314 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr1_+_156785425 0.312 ENST00000392302.2
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr22_-_38380543 0.291 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr3_-_69435224 0.286 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr3_-_69435428 0.279 ENST00000542259.1
FRMD4B
FERM domain containing 4B
chr12_+_52445191 0.277 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr20_+_2795626 0.273 ENST00000603872.1
ENST00000380589.4
C20orf141

chromosome 20 open reading frame 141

chr7_+_6714599 0.273 ENST00000328239.7
ENST00000542006.1
AC073343.1

Uncharacterized protein

chr12_+_54422142 0.269 ENST00000243108.4
HOXC6
homeobox C6
chr3_+_119814070 0.269 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr1_-_206671061 0.267 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr12_-_57871853 0.260 ENST00000549602.1
ENST00000430041.2
ARHGAP9

Rho GTPase activating protein 9

chr14_-_103589246 0.251 ENST00000558224.1
ENST00000560742.1
LINC00677

long intergenic non-protein coding RNA 677

chr6_-_142409936 0.249 ENST00000258042.1
NMBR
neuromedin B receptor
chr17_+_6918064 0.246 ENST00000546760.1
ENST00000552402.1
C17orf49

chromosome 17 open reading frame 49

chr3_-_100565249 0.245 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP


ABI family, member 3 (NESH) binding protein


chr1_-_242612726 0.242 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr17_+_6918093 0.239 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr15_+_91427691 0.233 ENST00000559355.1
ENST00000394302.1
FES

feline sarcoma oncogene

chr17_+_6918354 0.232 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr14_+_75988768 0.232 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr19_+_41869894 0.231 ENST00000413014.2
TMEM91
transmembrane protein 91
chr1_-_8000872 0.230 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_-_73511559 0.229 ENST00000521871.1
FBXO41
F-box protein 41
chr17_+_34058639 0.229 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr3_-_111852061 0.226 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM



germinal center-associated, signaling and motility



chr1_-_242612779 0.224 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr3_-_69249863 0.222 ENST00000478263.1
ENST00000462512.1
FRMD4B

FERM domain containing 4B

chr15_+_91411810 0.220 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr22_-_50708781 0.219 ENST00000449719.2
ENST00000330651.6
MAPK11

mitogen-activated protein kinase 11

chr10_-_118031778 0.218 ENST00000369236.1
GFRA1
GDNF family receptor alpha 1
chr15_+_59730348 0.218 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A



family with sequence similarity 81, member A



chr2_-_74781061 0.217 ENST00000264094.3
ENST00000393937.2
ENST00000409986.1
LOXL3


lysyl oxidase-like 3


chr1_+_155051305 0.211 ENST00000368408.3
EFNA3
ephrin-A3
chr15_+_91427642 0.209 ENST00000328850.3
ENST00000414248.2
FES

feline sarcoma oncogene

chr6_+_10634158 0.206 ENST00000379591.3
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr17_+_4854375 0.206 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3




enolase 3 (beta, muscle)




chr2_-_10220538 0.204 ENST00000381813.4
CYS1
cystin 1
chr9_+_82188077 0.201 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_+_128761363 0.200 ENST00000338350.4
KCNJ5
potassium inwardly-rectifying channel, subfamily J, member 5
chr1_+_155051379 0.197 ENST00000418360.2
EFNA3
ephrin-A3
chr1_-_112106556 0.193 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr3_-_192445289 0.193 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12



fibroblast growth factor 12



chr15_+_91427726 0.190 ENST00000452243.1
FES
feline sarcoma oncogene
chr1_-_112106578 0.188 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr3_-_156878482 0.185 ENST00000295925.4
CCNL1
cyclin L1
chr7_+_143826151 0.183 ENST00000408899.2
OR2A14
olfactory receptor, family 2, subfamily A, member 14
chr2_-_74645669 0.182 ENST00000518401.1
C2orf81
chromosome 2 open reading frame 81
chr16_+_22825475 0.181 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_+_37940153 0.181 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr3_-_156878540 0.180 ENST00000461804.1
CCNL1
cyclin L1
chr12_-_57871825 0.179 ENST00000548139.1
ARHGAP9
Rho GTPase activating protein 9
chr6_+_138188551 0.177 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr1_-_155006224 0.175 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr1_+_45274154 0.171 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19


BTB (POZ) domain containing 19


chr6_+_138188378 0.171 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_-_159893507 0.170 ENST00000368096.1
TAGLN2
transgelin 2
chr17_+_17685422 0.168 ENST00000395774.1
RAI1
retinoic acid induced 1
chr9_-_136344197 0.166 ENST00000414172.1
ENST00000371897.4
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr1_-_161279749 0.165 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ


myelin protein zero


chr7_+_100318423 0.165 ENST00000252723.2
EPO
erythropoietin
chr2_+_74154032 0.163 ENST00000356837.6
DGUOK
deoxyguanosine kinase
chr11_-_5271122 0.161 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr17_+_6926339 0.159 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr2_+_74153953 0.158 ENST00000264093.4
ENST00000348222.1
DGUOK

deoxyguanosine kinase

chr12_-_12849073 0.155 ENST00000332427.2
ENST00000540796.1
GPR19

G protein-coupled receptor 19

chr20_+_44746939 0.154 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr22_+_37257015 0.154 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
NCF4


neutrophil cytosolic factor 4, 40kDa


chr3_+_57261743 0.154 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr2_+_163175394 0.152 ENST00000446271.1
ENST00000429691.2
GCA

grancalcin, EF-hand calcium binding protein

chr20_+_44746885 0.151 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr18_-_72920372 0.149 ENST00000581620.1
ENST00000582437.1
ZADH2

zinc binding alcohol dehydrogenase domain containing 2

chr10_-_75401500 0.147 ENST00000359322.4
MYOZ1
myozenin 1
chr6_+_149539106 0.145 ENST00000443992.1
RP1-111D6.3
RP1-111D6.3
chrX_-_15288154 0.145 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9


ankyrin repeat and SOCS box containing 9


chr14_+_103589789 0.143 ENST00000558056.1
ENST00000560869.1
TNFAIP2

tumor necrosis factor, alpha-induced protein 2

chr18_-_72921303 0.142 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr2_+_11752379 0.140 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr19_-_5785630 0.139 ENST00000590343.1
ENST00000586012.1
DUS3L
CTB-54O9.9
dihydrouridine synthase 3-like (S. cerevisiae)
Uncharacterized protein
chr17_-_7108436 0.137 ENST00000493294.1
DLG4
discs, large homolog 4 (Drosophila)
chr14_+_75988851 0.136 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr6_-_111804905 0.135 ENST00000358835.3
ENST00000435970.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr13_-_50367057 0.135 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr14_+_20811722 0.134 ENST00000429687.3
PARP2
poly (ADP-ribose) polymerase 2
chr12_-_50101003 0.132 ENST00000550488.1
FMNL3
formin-like 3
chr3_-_49142178 0.132 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
QARS


glutaminyl-tRNA synthetase


chr14_-_69446034 0.132 ENST00000193403.6
ACTN1
actinin, alpha 1
chr14_+_20811766 0.132 ENST00000250416.5
ENST00000527915.1
PARP2

poly (ADP-ribose) polymerase 2

chr12_-_62997214 0.131 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr3_+_159481464 0.131 ENST00000467377.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr14_+_76127529 0.130 ENST00000556977.1
ENST00000557636.1
ENST00000286650.5
ENST00000298832.9
TTLL5



tubulin tyrosine ligase-like family, member 5



chr11_+_45792967 0.130 ENST00000378779.2
CTD-2210P24.4
Uncharacterized protein
chr1_+_221051699 0.130 ENST00000366903.6
HLX
H2.0-like homeobox
chrX_+_117861535 0.130 ENST00000371666.3
ENST00000371642.1
IL13RA1

interleukin 13 receptor, alpha 1

chr22_+_29999647 0.130 ENST00000334961.7
ENST00000353887.4
NF2

neurofibromin 2 (merlin)

chr6_+_138188351 0.128 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_-_209824643 0.128 ENST00000391911.1
ENST00000415782.1
LAMB3

laminin, beta 3

chr1_+_221054584 0.128 ENST00000549319.1
HLX
H2.0-like homeobox
chr19_-_42636543 0.128 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
POU2F2




POU class 2 homeobox 2




chr3_-_157221380 0.128 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr17_-_74236382 0.127 ENST00000592271.1
ENST00000319945.6
ENST00000269391.6
RNF157


ring finger protein 157


chr13_+_30002846 0.125 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr3_-_157221357 0.124 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chrX_-_138790348 0.122 ENST00000414978.1
ENST00000519895.1
MCF2

MCF.2 cell line derived transforming sequence

chr17_+_40440481 0.121 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A



signal transducer and activator of transcription 5A



chr12_+_110011571 0.121 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr13_+_28712614 0.121 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_+_159570722 0.120 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_-_74753332 0.119 ENST00000451518.1
ENST00000404568.3
DQX1

DEAQ box RNA-dependent ATPase 1

chrX_+_37208521 0.116 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr3_-_113775328 0.116 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407



KIAA1407



chr19_-_11529225 0.115 ENST00000567431.1
RGL3
ral guanine nucleotide dissociation stimulator-like 3
chr11_+_19799327 0.115 ENST00000540292.1
NAV2
neuron navigator 2
chr10_+_129705391 0.113 ENST00000442830.1
PTPRE
protein tyrosine phosphatase, receptor type, E
chr3_+_113775576 0.113 ENST00000485050.1
ENST00000281273.4
QTRTD1

queuine tRNA-ribosyltransferase domain containing 1

chr9_+_72002837 0.112 ENST00000377216.3
FAM189A2
family with sequence similarity 189, member A2
chr10_+_129705299 0.112 ENST00000254667.3
PTPRE
protein tyrosine phosphatase, receptor type, E
chr3_+_57261859 0.112 ENST00000495803.1
ENST00000444459.1
APPL1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

chr1_+_45478568 0.112 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chr6_-_88299678 0.111 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr22_+_29999545 0.110 ENST00000413209.2
ENST00000347330.5
ENST00000338641.4
ENST00000403435.1
ENST00000361452.4
ENST00000403999.3
NF2





neurofibromin 2 (merlin)





chr2_-_100721178 0.109 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr6_+_31554962 0.108 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1




leukocyte specific transcript 1




chr10_+_81838792 0.108 ENST00000372273.3
TMEM254
transmembrane protein 254
chr11_-_131533462 0.108 ENST00000416725.1
AP003039.3
AP003039.3
chr10_+_75757863 0.108 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL


vinculin


chr3_-_155011483 0.108 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr16_-_3545424 0.108 ENST00000437192.3
ENST00000399645.3
C16orf90

chromosome 16 open reading frame 90

chr13_+_30002741 0.107 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr11_+_18287801 0.106 ENST00000532858.1
ENST00000405158.2
SAA1

serum amyloid A1

chr8_+_27169138 0.105 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr19_-_40336969 0.105 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
FBL





fibrillarin





chr19_+_45504688 0.105 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr3_+_113775594 0.104 ENST00000479882.1
ENST00000493014.1
QTRTD1

queuine tRNA-ribosyltransferase domain containing 1

chr17_-_26127525 0.104 ENST00000313735.6
NOS2
nitric oxide synthase 2, inducible
chr13_-_30424821 0.104 ENST00000380680.4
UBL3
ubiquitin-like 3
chr11_+_18287721 0.103 ENST00000356524.4
SAA1
serum amyloid A1
chr3_-_119396193 0.103 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17


COX17 cytochrome c oxidase copper chaperone


chr6_-_74231303 0.101 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr14_-_69262789 0.101 ENST00000557022.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr6_-_74230741 0.101 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr11_-_72492903 0.101 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr19_+_18544045 0.101 ENST00000599699.2
SSBP4
single stranded DNA binding protein 4
chr7_+_30960915 0.101 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1


aquaporin 1 (Colton blood group)


chr22_+_18043133 0.100 ENST00000327451.6
ENST00000399813.1
SLC25A18

solute carrier family 25 (glutamate carrier), member 18

chr17_+_77021702 0.100 ENST00000392445.2
ENST00000354124.3
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr12_-_9913489 0.100 ENST00000228434.3
ENST00000536709.1
CD69

CD69 molecule

chr1_+_155006300 0.099 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1



DC-STAMP domain containing 1



chr8_+_27168988 0.099 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B


protein tyrosine kinase 2 beta


chr6_+_87865262 0.098 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr1_+_45477819 0.097 ENST00000246337.4
UROD
uroporphyrinogen decarboxylase
chr16_-_74734742 0.096 ENST00000308807.7
ENST00000573267.1
MLKL

mixed lineage kinase domain-like

chr1_-_155006254 0.096 ENST00000295536.5
DCST2
DC-STAMP domain containing 2
chr14_-_69445968 0.096 ENST00000438964.2
ACTN1
actinin, alpha 1
chr8_-_10512569 0.096 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr9_-_130477912 0.095 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr17_-_18908040 0.095 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr2_-_100987007 0.095 ENST00000595083.1
AC012493.2
Uncharacterized protein
chr11_+_47608198 0.094 ENST00000356737.2
ENST00000538490.1
FAM180B

family with sequence similarity 180, member B

chr15_+_49715449 0.094 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr10_-_81203972 0.094 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr2_-_74753305 0.094 ENST00000393951.2
DQX1
DEAQ box RNA-dependent ATPase 1
chr11_-_64856847 0.094 ENST00000524603.1
AP003068.6
transmembrane protein 262
chr7_+_30951461 0.094 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr11_+_19798964 0.093 ENST00000527559.2
NAV2
neuron navigator 2
chr1_-_40041925 0.093 ENST00000372862.3
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr3_-_16554403 0.093 ENST00000449415.1
ENST00000441460.1
RFTN1

raftlin, lipid raft linker 1

chr6_+_132891461 0.093 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr12_+_57854274 0.093 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr11_-_64570706 0.092 ENST00000294066.2
ENST00000377350.3
MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2

chr10_+_81838411 0.092 ENST00000372281.3
ENST00000372277.3
ENST00000372275.1
ENST00000372274.1
TMEM254



transmembrane protein 254



chr3_+_141205852 0.091 ENST00000286364.3
ENST00000452898.1
RASA2

RAS p21 protein activator 2

chr1_+_45477901 0.091 ENST00000434478.1
UROD
uroporphyrinogen decarboxylase
chr6_-_74231444 0.090 ENST00000331523.2
ENST00000356303.2
EEF1A1

eukaryotic translation elongation factor 1 alpha 1

chr12_+_10658201 0.089 ENST00000322446.3
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr12_-_57352103 0.088 ENST00000398138.3
RDH16
retinol dehydrogenase 16 (all-trans)
chr4_-_106817137 0.088 ENST00000510876.1
INTS12
integrator complex subunit 12
chr14_+_103243813 0.087 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3




TNF receptor-associated factor 3





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 1.1 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.5 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.2 0.9 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.2 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.5 GO:0021546 rhombomere development(GO:0021546)
0.1 0.2 GO:0030185 nitric oxide transport(GO:0030185) cellular response to mercury ion(GO:0071288)
0.1 0.3 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.2 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 1.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.5 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.1 0.3 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 1.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:2001202 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.3 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.2 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 0.1 GO:0002784 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.0 1.0 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.3 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.0 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:1903989 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 0.2 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.0 1.2 GO:0032982 myosin filament(GO:0032982)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.0 GO:1990923 PET complex(GO:1990923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.3 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.2 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors