Motif ID: HIC2

Z-value: 0.675


Transcription factors associated with HIC2:

Gene SymbolEntrez IDGene Name
HIC2 ENSG00000169635.5 HIC2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HIC2hg19_v2_chr22_+_21771656_217716930.791.1e-02Click!


Activity profile for motif HIC2.

activity profile for motif HIC2


Sorted Z-values histogram for motif HIC2

Sorted Z-values for motif HIC2



Network of associatons between targets according to the STRING database.



First level regulatory network of HIC2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_74659978 0.949 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1


cytochrome P450, family 11, subfamily A, polypeptide 1


chr17_+_1959369 0.858 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr5_+_176237478 0.852 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr2_+_128377550 0.770 ENST00000437387.1
ENST00000409090.1
MYO7B

myosin VIIB

chr12_-_49488573 0.758 ENST00000266991.2
DHH
desert hedgehog
chrX_-_137793826 0.665 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr9_-_130616915 0.651 ENST00000344849.3
ENG
endoglin
chr14_-_94856951 0.611 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
SERPINA1



serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1



chr14_-_94856987 0.558 ENST00000449399.3
ENST00000404814.4
SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

chr17_+_39975455 0.554 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_-_26903900 0.544 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC



aldolase C, fructose-bisphosphate



chrX_-_138287168 0.530 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr5_+_166711804 0.515 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr19_+_36347787 0.514 ENST00000347900.6
ENST00000360202.5
KIRREL2

kin of IRRE like 2 (Drosophila)

chr1_-_50489547 0.510 ENST00000371836.1
ENST00000371839.1
ENST00000371838.1
AGBL4


ATP/GTP binding protein-like 4


chr3_+_164924716 0.509 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2

RP11-85M11.2

chr5_+_167181917 0.497 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr19_+_41281060 0.496 ENST00000594436.1
ENST00000597784.1
MIA

melanoma inhibitory activity

chr19_+_50031547 0.494 ENST00000597801.1
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr10_+_102106829 0.486 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr1_+_205473720 0.477 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18


cyclin-dependent kinase 18


chr18_+_43304137 0.468 ENST00000502059.2
ENST00000586951.1
ENST00000589322.2
ENST00000415427.3
ENST00000535474.1
ENST00000402943.2
SLC14A1





solute carrier family 14 (urea transporter), member 1 (Kidd blood group)





chr17_+_1958388 0.465 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr4_+_183164574 0.442 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr5_+_167182003 0.431 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr13_-_46716969 0.430 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_31360887 0.427 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)


chr12_+_6933660 0.423 ENST00000545321.1
GPR162
G protein-coupled receptor 162
chr6_+_12749657 0.419 ENST00000406205.2
PHACTR1
phosphatase and actin regulator 1
chr1_+_203097407 0.417 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr14_-_94857004 0.409 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
SERPINA1




serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1




chr22_-_20367797 0.405 ENST00000424787.2
GGTLC3
gamma-glutamyltransferase light chain 3
chr20_+_2795626 0.402 ENST00000603872.1
ENST00000380589.4
C20orf141

chromosome 20 open reading frame 141

chr1_-_24438664 0.393 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
MYOM3


myomesin 3


chr17_+_39975544 0.391 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr2_-_31361362 0.388 ENST00000430167.1
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr13_-_36705425 0.379 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1


doublecortin-like kinase 1


chr22_-_32651326 0.378 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr1_+_76540386 0.367 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr20_+_42965626 0.355 ENST00000217043.2
R3HDML
R3H domain containing-like
chr2_-_31361543 0.337 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr12_+_54447637 0.331 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr19_+_11649532 0.319 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1


calponin 1, basic, smooth muscle


chr1_+_205473784 0.317 ENST00000478560.1
ENST00000443813.2
CDK18

cyclin-dependent kinase 18

chr1_-_156786634 0.312 ENST00000392306.2
ENST00000368199.3
SH2D2A

SH2 domain containing 2A

chr4_-_186733363 0.312 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr19_-_7698599 0.302 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr1_-_156786530 0.301 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr15_+_90319557 0.300 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chrX_+_12156582 0.299 ENST00000380682.1
FRMPD4
FERM and PDZ domain containing 4
chr15_+_84322827 0.297 ENST00000286744.5
ENST00000567476.1
ADAMTSL3

ADAMTS-like 3

chr6_+_12958137 0.297 ENST00000457702.2
ENST00000379345.2
PHACTR1

phosphatase and actin regulator 1

chr7_+_128784712 0.290 ENST00000289407.4
TSPAN33
tetraspanin 33
chr19_+_54496132 0.289 ENST00000346968.2
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chrX_+_55246771 0.289 ENST00000289619.5
ENST00000374955.3
PAGE5

P antigen family, member 5 (prostate associated)

chrX_-_138304939 0.286 ENST00000448673.1
FGF13
fibroblast growth factor 13
chrX_-_112084043 0.279 ENST00000304758.1
AMOT
angiomotin
chr5_+_15500280 0.276 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr14_-_80677613 0.276 ENST00000556811.1
DIO2
deiodinase, iodothyronine, type II
chr1_-_27240455 0.273 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr12_-_58159361 0.273 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr5_+_135385202 0.272 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr19_-_4791219 0.270 ENST00000598782.1
AC005523.3
AC005523.3
chr15_-_79103757 0.269 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr18_+_43304092 0.265 ENST00000321925.4
ENST00000587601.1
SLC14A1

solute carrier family 14 (urea transporter), member 1 (Kidd blood group)

chr1_+_205473865 0.264 ENST00000506215.1
ENST00000419301.1
CDK18

cyclin-dependent kinase 18

chr21_-_15918618 0.264 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr15_-_85201779 0.261 ENST00000360476.3
ENST00000394588.3
NMB

neuromedin B

chr22_+_21321531 0.259 ENST00000405089.1
ENST00000335375.5
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr3_-_9595480 0.259 ENST00000287585.6
LHFPL4
lipoma HMGIC fusion partner-like 4
chr9_+_134165195 0.259 ENST00000372261.1
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr5_+_176784837 0.257 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chr12_-_57871853 0.257 ENST00000549602.1
ENST00000430041.2
ARHGAP9

Rho GTPase activating protein 9

chr7_+_8474150 0.256 ENST00000602349.1
NXPH1
neurexophilin 1
chr13_+_113633620 0.254 ENST00000421756.1
ENST00000375601.3
MCF2L

MCF.2 cell line derived transforming sequence-like

chr20_+_61287711 0.254 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr22_+_42095497 0.253 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1



meiosis inhibitor 1



chr1_+_156830607 0.248 ENST00000368196.3
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr9_+_135285579 0.245 ENST00000343036.2
ENST00000393216.2
C9orf171

chromosome 9 open reading frame 171

chr19_-_6375860 0.244 ENST00000245810.1
PSPN
persephin
chr1_+_156830678 0.243 ENST00000524377.1
ENST00000358660.3
NTRK1

neurotrophic tyrosine kinase, receptor, type 1

chr9_+_112403059 0.243 ENST00000374531.2
PALM2
paralemmin 2
chr19_-_56048456 0.239 ENST00000413299.1
SBK2
SH3 domain binding kinase family, member 2
chr20_-_31071239 0.237 ENST00000359676.5
C20orf112
chromosome 20 open reading frame 112
chr4_-_186732892 0.235 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chr2_-_73511559 0.233 ENST00000521871.1
FBXO41
F-box protein 41
chr11_+_61717279 0.231 ENST00000378043.4
BEST1
bestrophin 1
chr22_+_25003626 0.229 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1


gamma-glutamyltransferase 1


chr5_-_147286065 0.225 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr14_+_42076765 0.221 ENST00000298119.4
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr11_+_131781290 0.221 ENST00000425719.2
ENST00000374784.1
NTM

neurotrimin

chrX_+_55246818 0.220 ENST00000374952.1
PAGE5
P antigen family, member 5 (prostate associated)
chr9_+_112403088 0.220 ENST00000448454.2
PALM2
paralemmin 2
chr11_-_65641044 0.217 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr9_+_135285430 0.217 ENST00000393215.3
C9orf171
chromosome 9 open reading frame 171
chr17_-_17726907 0.217 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chr19_+_641178 0.215 ENST00000166133.3
FGF22
fibroblast growth factor 22
chr16_+_88704978 0.215 ENST00000244241.4
IL17C
interleukin 17C
chr22_-_27620603 0.215 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1

RP5-1172A22.1

chr3_+_46921732 0.214 ENST00000418619.1
PTH1R
parathyroid hormone 1 receptor
chr1_+_10057274 0.213 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr7_+_155090271 0.213 ENST00000476756.1
INSIG1
insulin induced gene 1
chr17_-_56405407 0.212 ENST00000343736.4
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chr13_+_100634004 0.211 ENST00000376335.3
ZIC2
Zic family member 2
chr22_+_25003606 0.211 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr11_+_7597639 0.208 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_+_124761200 0.206 ENST00000524433.1
RP11-664I21.6
Uncharacterized protein
chr12_-_57871825 0.206 ENST00000548139.1
ARHGAP9
Rho GTPase activating protein 9
chr16_+_56226405 0.205 ENST00000565363.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr8_+_104892639 0.204 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr20_+_1875378 0.203 ENST00000356025.3
SIRPA
signal-regulatory protein alpha
chr20_+_61299155 0.202 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr19_+_42254885 0.202 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr4_-_7436671 0.202 ENST00000319098.4
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr18_+_43409037 0.199 ENST00000546268.1
SIGLEC15
sialic acid binding Ig-like lectin 15
chr14_-_63512154 0.199 ENST00000322893.7
KCNH5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr6_+_151646800 0.196 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr20_+_36974759 0.194 ENST00000217407.2
LBP
lipopolysaccharide binding protein
chr1_-_48462566 0.194 ENST00000606738.2
TRABD2B
TraB domain containing 2B
chr5_-_136834242 0.192 ENST00000282223.7
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr17_+_43971643 0.192 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT





microtubule-associated protein tau





chr13_+_27131798 0.192 ENST00000361042.4
WASF3
WAS protein family, member 3
chr2_-_74645669 0.185 ENST00000518401.1
C2orf81
chromosome 2 open reading frame 81
chr4_-_153601136 0.184 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr2_-_45162783 0.184 ENST00000432125.2
RP11-89K21.1
RP11-89K21.1
chr17_-_56406117 0.182 ENST00000268893.6
ENST00000355701.3
BZRAP1

benzodiazepine receptor (peripheral) associated protein 1

chr3_+_124355944 0.181 ENST00000459915.1
KALRN
kalirin, RhoGEF kinase
chr11_+_117070037 0.181 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chr13_+_52158610 0.180 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr13_+_103451548 0.180 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr22_-_20368028 0.180 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr13_+_103451399 0.180 ENST00000257336.1
ENST00000448849.2
BIVM

basic, immunoglobulin-like variable motif containing

chr22_+_25003568 0.179 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr14_-_101034407 0.178 ENST00000443071.2
ENST00000557378.1
BEGAIN

brain-enriched guanylate kinase-associated

chr3_-_127541194 0.178 ENST00000453507.2
MGLL
monoglyceride lipase
chr19_+_8740061 0.177 ENST00000593792.1
CTD-2586B10.1
CTD-2586B10.1
chr1_+_210502238 0.176 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
HHAT





hedgehog acyltransferase





chr12_-_15038779 0.176 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chrX_-_153141783 0.175 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr4_-_176923483 0.175 ENST00000280187.7
ENST00000512509.1
GPM6A

glycoprotein M6A

chr15_-_74658493 0.174 ENST00000419019.2
ENST00000569662.1
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr11_+_7618413 0.174 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_48632593 0.174 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr12_+_72667203 0.173 ENST00000547300.1
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr11_+_61717336 0.173 ENST00000378042.3
BEST1
bestrophin 1
chr22_+_24115000 0.173 ENST00000215743.3
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr11_-_60623437 0.172 ENST00000332539.4
PTGDR2
prostaglandin D2 receptor 2
chr22_+_31518938 0.172 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr5_+_140474181 0.171 ENST00000194155.4
PCDHB2
protocadherin beta 2
chrX_-_153151586 0.171 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1CAM


L1 cell adhesion molecule


chr2_-_74776586 0.171 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr3_-_69435224 0.170 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr17_-_62066769 0.170 ENST00000577329.1
CTC-264K15.6
CTC-264K15.6
chr6_-_133035185 0.169 ENST00000367928.4
VNN1
vanin 1
chr11_+_61595752 0.169 ENST00000521849.1
FADS2
fatty acid desaturase 2
chr1_-_2461684 0.169 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr1_+_153746683 0.169 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr12_+_93964158 0.168 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr1_-_166136187 0.168 ENST00000338353.3
FAM78B
family with sequence similarity 78, member B
chr5_+_156693091 0.167 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2



cytoplasmic FMR1 interacting protein 2



chr3_-_69435428 0.167 ENST00000542259.1
FRMD4B
FERM domain containing 4B
chr5_-_136834263 0.166 ENST00000505690.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr11_+_61595572 0.164 ENST00000517312.1
FADS2
fatty acid desaturase 2
chr19_-_10697895 0.164 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2




adaptor-related protein complex 1, mu 2 subunit




chr6_+_31554962 0.164 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1




leukocyte specific transcript 1




chr3_+_111578640 0.163 ENST00000393925.3
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr17_+_43972010 0.163 ENST00000334239.8
ENST00000446361.3
MAPT

microtubule-associated protein tau

chr8_-_133493200 0.162 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr9_-_79307096 0.161 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2


prune homolog 2 (Drosophila)


chr11_-_63933504 0.161 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr10_+_99627889 0.161 ENST00000596005.1
GOLGA7B
Golgin subfamily A member 7B; cDNA FLJ43465 fis, clone OCBBF2036476
chr7_+_140372953 0.160 ENST00000072869.4
ENST00000476491.1
ADCK2

aarF domain containing kinase 2

chr19_+_36027660 0.159 ENST00000585510.1
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr3_+_159570722 0.158 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr15_-_40212363 0.157 ENST00000299092.3
GPR176
G protein-coupled receptor 176
chr1_-_173638976 0.156 ENST00000333279.2
ANKRD45
ankyrin repeat domain 45
chr17_-_7123021 0.156 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr10_+_82297658 0.155 ENST00000339284.2
SH2D4B
SH2 domain containing 4B
chr20_-_31071309 0.154 ENST00000326071.4
C20orf112
chromosome 20 open reading frame 112
chr4_-_119274121 0.153 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr21_-_16374688 0.153 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr22_-_20138302 0.153 ENST00000540078.1
ENST00000439765.2
AC006547.14

uncharacterized protein LOC388849

chr9_-_107690420 0.152 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr3_+_125985620 0.152 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1

RP11-71E19.1

chr20_-_62680984 0.151 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr4_-_1657135 0.151 ENST00000489029.1
FAM53A
family with sequence similarity 53, member A
chr12_+_93965609 0.151 ENST00000549887.1
ENST00000551556.1
SOCS2

suppressor of cytokine signaling 2

chr3_+_111393659 0.148 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr19_-_55669093 0.147 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr14_+_52313833 0.147 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr1_-_166135952 0.147 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr1_+_156611900 0.147 ENST00000457777.2
ENST00000424639.1
BCAN

brevican

chr22_+_45680822 0.146 ENST00000216211.4
ENST00000396082.2
UPK3A

uroplakin 3A

chr16_+_29466426 0.145 ENST00000567248.1
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr6_-_142409936 0.145 ENST00000258042.1
NMBR
neuromedin B receptor
chr1_+_203096831 0.145 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr3_+_111578583 0.144 ENST00000478922.1
ENST00000477695.1
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr4_-_186733119 0.144 ENST00000419063.1
SORBS2
sorbin and SH3 domain containing 2
chr5_+_156693159 0.143 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_+_61717535 0.143 ENST00000534553.1
ENST00000301774.9
BEST1

bestrophin 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.9 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.7 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.6 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.2 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.7 GO:1904970 brush border assembly(GO:1904970)
0.1 0.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.5 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.1 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666)
0.1 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 1.9 GO:0097264 self proteolysis(GO:0097264)
0.1 0.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.2 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.5 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.2 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.6 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.2 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 1.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.7 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.2 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.3 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.1 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.0 GO:1900086 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.0 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.3 GO:0051604 protein maturation(GO:0051604)
0.0 0.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) disaccharide biosynthetic process(GO:0046351)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.4 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.0 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.0 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0051105 regulation of DNA ligation(GO:0051105)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.0 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.4 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 1.4 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0006833 water transport(GO:0006833)
0.0 0.0 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) histone H3-R17 methylation(GO:0034971) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.0 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:1901563 cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.0 GO:0034059 response to anoxia(GO:0034059)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0046066 dGDP metabolic process(GO:0046066)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.0 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.0 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0045141 meiotic telomere clustering(GO:0045141)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.0 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.0 GO:1901624 negative regulation of chemokine-mediated signaling pathway(GO:0070100) negative regulation of lymphocyte chemotaxis(GO:1901624)
0.0 0.1 GO:1903115 regulation of actin filament-based movement(GO:1903115)
0.0 0.0 GO:1901079 positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.0 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.0 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:1904479 negative regulation of intestinal absorption(GO:1904479)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 3.0 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.0 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.0 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.7 GO:0015265 urea channel activity(GO:0015265)
0.1 0.9 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.4 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.3 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.7 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0016462 pyrophosphatase activity(GO:0016462)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.0 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.0 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 1.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.1 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.7 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME_INFLUENZA_LIFE_CYCLE Genes involved in Influenza Life Cycle
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse