Motif ID: HIC1

Z-value: 0.705


Transcription factors associated with HIC1:

Gene SymbolEntrez IDGene Name
HIC1 ENSG00000177374.8 HIC1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HIC1hg19_v2_chr17_+_1959369_1959604-0.908.4e-04Click!


Activity profile for motif HIC1.

activity profile for motif HIC1


Sorted Z-values histogram for motif HIC1

Sorted Z-values for motif HIC1



Network of associatons between targets according to the STRING database.



First level regulatory network of HIC1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_17035943 1.399 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7



pleckstrin homology domain containing, family A member 7



chr4_-_25864581 1.272 ENST00000399878.3
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr16_-_65155833 1.085 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11


cadherin 11, type 2, OB-cadherin (osteoblast)


chrX_-_102565858 1.012 ENST00000449185.1
ENST00000536889.1
BEX2

brain expressed X-linked 2

chr1_+_9352939 0.897 ENST00000328089.6
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr15_+_94774767 0.827 ENST00000543482.1
MCTP2
multiple C2 domains, transmembrane 2
chr12_-_45270077 0.789 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr4_-_25865159 0.767 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chrX_-_102565932 0.735 ENST00000372674.1
ENST00000372677.3
BEX2

brain expressed X-linked 2

chr11_+_121322832 0.711 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr7_-_124405681 0.694 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr3_-_185542761 0.672 ENST00000457616.2
ENST00000346192.3
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr6_+_31865552 0.665 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr3_-_185542817 0.637 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr6_+_56819773 0.634 ENST00000370750.2
BEND6
BEN domain containing 6
chr17_+_72427477 0.623 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr3_-_38691119 0.614 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A




sodium channel, voltage-gated, type V, alpha subunit




chr2_+_46524537 0.610 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr2_+_154728426 0.588 ENST00000392825.3
ENST00000434213.1
GALNT13

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)

chr12_-_96184533 0.561 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr4_-_24914576 0.560 ENST00000502801.1
ENST00000428116.2
CCDC149

coiled-coil domain containing 149

chr12_-_45270151 0.552 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr7_+_155250824 0.547 ENST00000297375.4
EN2
engrailed homeobox 2
chr17_+_72426891 0.540 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_+_7005959 0.537 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr9_+_504674 0.526 ENST00000382297.2
KANK1
KN motif and ankyrin repeat domains 1
chr7_-_82073109 0.523 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr11_+_65779283 0.522 ENST00000312134.2
CST6
cystatin E/M
chr7_-_82073031 0.521 ENST00000356253.5
ENST00000423588.1
CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1

chr1_+_110453203 0.508 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1


colony stimulating factor 1 (macrophage)


chr13_-_95364389 0.503 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr2_-_99552620 0.496 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L


KIAA1211-like


chr2_+_207308539 0.484 ENST00000374416.1
ENST00000374415.3
ADAM23

ADAM metallopeptidase domain 23

chr16_+_89642120 0.481 ENST00000268720.5
ENST00000319518.8
CPNE7

copine VII

chr6_+_56820018 0.481 ENST00000370746.3
BEND6
BEN domain containing 6
chr4_+_86396321 0.476 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr12_-_96184913 0.475 ENST00000538383.1
NTN4
netrin 4
chr7_+_94536898 0.470 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr4_-_24914508 0.461 ENST00000504487.1
CCDC149
coiled-coil domain containing 149
chr6_+_56819895 0.460 ENST00000370748.3
BEND6
BEN domain containing 6
chr17_-_6459802 0.457 ENST00000262483.8
PITPNM3
PITPNM family member 3
chr6_+_19837592 0.454 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr2_-_27718052 0.452 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr22_+_33197683 0.445 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr17_+_19437132 0.443 ENST00000436810.2
ENST00000270570.4
ENST00000457293.1
ENST00000542886.1
ENST00000575023.1
ENST00000395585.1
SLC47A1





solute carrier family 47 (multidrug and toxin extrusion), member 1





chr9_-_130742792 0.441 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr21_+_46825032 0.438 ENST00000400337.2
COL18A1
collagen, type XVIII, alpha 1
chr16_+_19179549 0.436 ENST00000355377.2
ENST00000568115.1
SYT17

synaptotagmin XVII

chr7_-_95025661 0.435 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3


paraoxonase 1
paraoxonase 3


chr1_+_23037323 0.434 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2



EPH receptor B2



chr17_-_6459768 0.431 ENST00000421306.3
PITPNM3
PITPNM family member 3
chr2_-_166650700 0.429 ENST00000422973.1
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr12_+_71833550 0.425 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr1_-_60392452 0.425 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr5_+_133450365 0.424 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7




transcription factor 7 (T-cell specific, HMG-box)




chr7_-_132262060 0.407 ENST00000359827.3
PLXNA4
plexin A4
chr8_+_26434578 0.406 ENST00000493789.2
DPYSL2
dihydropyrimidinase-like 2
chr3_+_171758344 0.404 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr18_-_45663666 0.403 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chrX_+_38420783 0.396 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7


tetraspanin 7


chr5_-_146889619 0.392 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr16_-_4987065 0.385 ENST00000590782.2
ENST00000345988.2
PPL

periplakin

chrX_-_8700171 0.381 ENST00000262648.3
KAL1
Kallmann syndrome 1 sequence
chrX_-_45710920 0.379 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr18_-_45935663 0.378 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
ZBTB7C







zinc finger and BTB domain containing 7C







chr8_+_98881268 0.377 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2


matrilin 2


chr1_-_32801825 0.377 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chrX_+_38420623 0.376 ENST00000378482.2
TSPAN7
tetraspanin 7
chr2_+_65216462 0.375 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_-_110583451 0.374 ENST00000260283.4
ENST00000528829.1
ARHGAP20

Rho GTPase activating protein 20

chr6_+_147830362 0.373 ENST00000566741.1
SAMD5
sterile alpha motif domain containing 5
chr4_-_109684120 0.368 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL



ethanolamine-phosphate phospho-lyase



chr1_+_6845384 0.364 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr2_-_224903995 0.363 ENST00000409304.1
ENST00000454956.1
ENST00000258405.4
SERPINE2


serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2


chr8_-_41166953 0.359 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr1_-_111746966 0.358 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr7_-_122526799 0.357 ENST00000334010.7
ENST00000313070.7
CADPS2

Ca++-dependent secretion activator 2

chr5_+_179233376 0.349 ENST00000376929.3
ENST00000514093.1
SQSTM1

sequestosome 1

chrX_+_153686614 0.349 ENST00000369682.3
PLXNA3
plexin A3
chr9_-_112083229 0.345 ENST00000374566.3
ENST00000374557.4
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr11_-_110582773 0.343 ENST00000524756.1
ARHGAP20
Rho GTPase activating protein 20
chr18_+_21269404 0.342 ENST00000313654.9
LAMA3
laminin, alpha 3
chr18_+_21269556 0.342 ENST00000399516.3
LAMA3
laminin, alpha 3
chr9_+_135037334 0.342 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2



netrin G2



chr7_-_132261253 0.341 ENST00000321063.4
PLXNA4
plexin A4
chr21_+_35445827 0.340 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr4_+_15005391 0.335 ENST00000507071.1
ENST00000345451.3
ENST00000259997.5
ENST00000382395.3
ENST00000382401.3
CPEB2




cytoplasmic polyadenylation element binding protein 2




chr13_+_96743093 0.329 ENST00000376705.2
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr1_+_169075554 0.328 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr6_-_94129244 0.328 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr7_+_128577972 0.324 ENST00000357234.5
ENST00000477535.1
ENST00000479582.1
ENST00000464557.1
ENST00000402030.2
IRF5




interferon regulatory factor 5




chr5_-_141257954 0.322 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1



protocadherin 1



chr7_+_94537542 0.322 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr8_-_109799793 0.321 ENST00000297459.3
TMEM74
transmembrane protein 74
chr7_+_97840739 0.318 ENST00000609256.1
BHLHA15
basic helix-loop-helix family, member a15
chr1_-_8086343 0.318 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1


ERBB receptor feedback inhibitor 1


chr8_-_41754231 0.318 ENST00000265709.8
ANK1
ankyrin 1, erythrocytic
chr14_+_105941118 0.315 ENST00000550577.1
ENST00000538259.2
CRIP2

cysteine-rich protein 2

chr4_+_91048706 0.314 ENST00000509176.1
CCSER1
coiled-coil serine-rich protein 1
chr18_-_21242774 0.311 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr2_+_207308220 0.309 ENST00000264377.3
ADAM23
ADAM metallopeptidase domain 23
chr1_+_31886653 0.309 ENST00000536384.1
SERINC2
serine incorporator 2
chr18_-_21242833 0.305 ENST00000586087.1
ENST00000592179.1
ANKRD29

ankyrin repeat domain 29

chr2_-_7005785 0.302 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2


cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial


chr8_-_110703819 0.301 ENST00000532779.1
ENST00000534578.1
SYBU

syntabulin (syntaxin-interacting)

chr1_+_6845497 0.300 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr17_-_16472483 0.299 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287


zinc finger protein 287


chr4_-_2420335 0.299 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr9_-_38424443 0.298 ENST00000377694.1
IGFBPL1
insulin-like growth factor binding protein-like 1
chr18_+_70536215 0.298 ENST00000578967.1
RP11-676J15.1
RP11-676J15.1
chr7_+_73082152 0.294 ENST00000324941.4
ENST00000451519.1
VPS37D

vacuolar protein sorting 37 homolog D (S. cerevisiae)

chr4_+_1795012 0.294 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
FGFR3



fibroblast growth factor receptor 3



chr17_+_4402133 0.293 ENST00000329078.3
SPNS2
spinster homolog 2 (Drosophila)
chr9_+_91606355 0.292 ENST00000358157.2
S1PR3
sphingosine-1-phosphate receptor 3
chr6_-_18122843 0.292 ENST00000340650.3
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1
chr7_-_122526411 0.291 ENST00000449022.2
CADPS2
Ca++-dependent secretion activator 2
chr12_+_133067157 0.290 ENST00000261673.6
FBRSL1
fibrosin-like 1
chr7_-_130418888 0.289 ENST00000310992.4
KLF14
Kruppel-like factor 14
chr14_-_105635090 0.289 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr6_-_56819385 0.287 ENST00000370754.5
ENST00000449297.2
DST

dystonin

chr8_+_124194752 0.286 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr20_+_13202418 0.285 ENST00000262487.4
ISM1
isthmin 1, angiogenesis inhibitor
chr3_+_50192833 0.284 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_-_120685608 0.282 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_+_10270863 0.278 ENST00000377093.4
ENST00000263934.6
KIF1B

kinesin family member 1B

chr12_-_45269769 0.276 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr4_+_72052964 0.276 ENST00000264485.5
ENST00000425175.1
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chr2_+_128405655 0.275 ENST00000423019.1
GPR17
G protein-coupled receptor 17
chr12_-_52585765 0.271 ENST00000313234.5
ENST00000394815.2
KRT80

keratin 80

chr10_+_75670862 0.267 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
PLAU


plasminogen activator, urokinase


chr8_+_38614754 0.266 ENST00000521642.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr6_+_7727030 0.264 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr4_-_2420357 0.264 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28


zinc finger, FYVE domain containing 28


chr15_+_92396920 0.261 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr2_+_204192942 0.260 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr1_+_110453462 0.258 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr18_-_30050395 0.257 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr1_+_110453109 0.256 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr16_-_89268070 0.254 ENST00000562855.2
SLC22A31
solute carrier family 22, member 31
chr1_-_9970383 0.254 ENST00000400904.3
CTNNBIP1
catenin, beta interacting protein 1
chr8_+_22224760 0.251 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr15_+_50474385 0.250 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr17_-_67323385 0.247 ENST00000588665.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr4_+_15004165 0.246 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2


cytoplasmic polyadenylation element binding protein 2


chr3_+_42544084 0.246 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
VIPR1



vasoactive intestinal peptide receptor 1



chr2_+_202899310 0.246 ENST00000286201.1
FZD7
frizzled family receptor 7
chr7_+_94537247 0.245 ENST00000422324.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr4_-_75719896 0.243 ENST00000395743.3
BTC
betacellulin
chr20_-_50179368 0.242 ENST00000609943.1
ENST00000609507.1
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr4_+_150999418 0.240 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr11_+_120382417 0.237 ENST00000527524.2
ENST00000375081.2
GRIK4
AP002348.1
glutamate receptor, ionotropic, kainate 4
Uncharacterized protein
chr10_-_21786179 0.236 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr4_+_72053017 0.235 ENST00000351898.6
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr15_+_92397051 0.235 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr11_-_62389577 0.235 ENST00000534715.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr1_-_9970227 0.233 ENST00000377263.1
CTNNBIP1
catenin, beta interacting protein 1
chr19_+_45844032 0.232 ENST00000589837.1
KLC3
kinesin light chain 3
chr3_-_169899504 0.232 ENST00000474275.1
ENST00000484931.1
ENST00000494943.1
ENST00000497658.1
ENST00000465896.1
ENST00000475729.1
ENST00000495893.2
ENST00000481639.1
ENST00000467570.1
ENST00000466189.1
PHC3









polyhomeotic homolog 3 (Drosophila)









chr5_+_111755280 0.231 ENST00000600409.1
EPB41L4A-AS2
EPB41L4A antisense RNA 2 (head to head)
chr14_+_62331592 0.229 ENST00000554436.1
CTD-2277K2.1
CTD-2277K2.1
chr3_+_179370517 0.229 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr16_-_67700594 0.228 ENST00000602644.1
ENST00000243878.4
ENKD1

enkurin domain containing 1

chr19_+_35521572 0.227 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr21_+_38338737 0.227 ENST00000430068.1
AP000704.5
AP000704.5
chrX_+_37545012 0.226 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr8_+_38614778 0.226 ENST00000521050.1
ENST00000522904.1
TACC1

transforming, acidic coiled-coil containing protein 1

chr16_-_755726 0.225 ENST00000324361.5
FBXL16
F-box and leucine-rich repeat protein 16
chr10_-_104001231 0.225 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr19_-_5340730 0.224 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr8_-_125740514 0.224 ENST00000325064.5
ENST00000518547.1
MTSS1

metastasis suppressor 1

chr7_-_127672146 0.224 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr7_-_50860565 0.223 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr2_-_233792837 0.222 ENST00000373552.4
ENST00000409079.1
NGEF

neuronal guanine nucleotide exchange factor

chr11_-_65816591 0.222 ENST00000312006.4
GAL3ST3
galactose-3-O-sulfotransferase 3
chr18_+_19749386 0.221 ENST00000269216.3
GATA6
GATA binding protein 6
chr2_+_217498105 0.221 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr10_+_122216707 0.221 ENST00000427079.1
ENST00000541332.1
PPAPDC1A

phosphatidic acid phosphatase type 2 domain containing 1A

chr22_+_24819565 0.220 ENST00000424232.1
ENST00000486108.1
ADORA2A

adenosine A2a receptor

chr4_-_149365827 0.220 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr8_-_60031762 0.220 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr6_-_17987694 0.219 ENST00000378814.5
ENST00000378843.2
ENST00000378826.2
ENST00000378816.5
ENST00000259711.6
ENST00000502704.1
KIF13A





kinesin family member 13A





chr15_+_50474412 0.218 ENST00000380902.4
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr4_+_3768075 0.214 ENST00000509482.1
ENST00000330055.5
ADRA2C

adrenoceptor alpha 2C

chr2_-_197458271 0.214 ENST00000427457.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr10_+_122216316 0.213 ENST00000398250.1
ENST00000439221.1
ENST00000398248.1
PPAPDC1A


phosphatidic acid phosphatase type 2 domain containing 1A


chr6_+_56820152 0.213 ENST00000370745.1
BEND6
BEN domain containing 6
chr18_+_59992514 0.213 ENST00000269485.7
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr7_-_50861129 0.212 ENST00000439044.1
ENST00000402497.1
ENST00000335866.3
GRB10


growth factor receptor-bound protein 10


chr7_-_122526499 0.212 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr7_+_2559399 0.212 ENST00000222725.5
ENST00000359574.3
LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr8_-_19614810 0.211 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr16_+_14396121 0.211 ENST00000570945.1
RP11-65J21.3
RP11-65J21.3
chr1_+_6845578 0.210 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr4_+_6784358 0.210 ENST00000508423.1
KIAA0232
KIAA0232
chr2_-_211090162 0.206 ENST00000233710.3
ACADL
acyl-CoA dehydrogenase, long chain
chr6_+_147830063 0.206 ENST00000367474.1
SAMD5
sterile alpha motif domain containing 5
chr3_+_69788576 0.204 ENST00000352241.4
ENST00000448226.2
MITF

microphthalmia-associated transcription factor

chr17_-_48943706 0.203 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr2_-_157198860 0.203 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr19_+_708910 0.203 ENST00000264560.7
PALM
paralemmin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.3 1.0 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.7 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 1.7 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 1.0 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 1.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.5 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2 0.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 1.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.6 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.4 GO:0071812 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 0.8 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.5 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.6 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.1 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 1.3 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.3 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.4 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.2 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.2 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.3 GO:1904647 response to rotenone(GO:1904647)
0.1 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.2 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 0.2 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 1.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.7 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.1 0.2 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.2 GO:0097187 dentinogenesis(GO:0097187)
0.1 0.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.1 GO:1900077 negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139) positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.3 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.1 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.4 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:0019230 pathogenesis(GO:0009405) proprioception(GO:0019230)
0.0 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.3 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.8 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.5 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.2 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.2 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 2.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.0 0.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.4 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.0 0.1 GO:1903393 positive regulation of adherens junction organization(GO:1903393)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.0 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.5 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.0 GO:0006816 calcium ion transport(GO:0006816)
0.0 0.7 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.5 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.5 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.3 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0099515 nuclear migration along microfilament(GO:0031022) actin filament-based transport(GO:0099515)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.0 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.0 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular endothelium development(GO:0072011) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.0 GO:0043449 cellular alkene metabolic process(GO:0043449) olefin metabolic process(GO:1900673)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.0 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.0 GO:0010256 endomembrane system organization(GO:0010256)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.0 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0009304 transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.3 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.0 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.0 GO:1903400 L-arginine transmembrane transport(GO:1903400) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0098869 detoxification(GO:0098754) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.0 GO:0044326 dendritic spine neck(GO:0044326)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.5 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.5 GO:0005915 zonula adherens(GO:0005915)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.0 GO:0097444 spine apparatus(GO:0097444)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0000785 chromatin(GO:0000785)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.3 1.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 1.6 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.4 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 1.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.0 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0030305 heparanase activity(GO:0030305)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.4 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.4 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.2 GO:0005220 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.2 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.1 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 1.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 1.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0035673 oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.0 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 2.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 3.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.0 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport