Motif ID: HES1

Z-value: 0.932


Transcription factors associated with HES1:

Gene SymbolEntrez IDGene Name
HES1 ENSG00000114315.3 HES1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_193853944-0.761.8e-02Click!


Activity profile for motif HES1.

activity profile for motif HES1


Sorted Z-values histogram for motif HES1

Sorted Z-values for motif HES1



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_161039647 1.551 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr1_-_161039753 1.538 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr7_-_140340576 1.516 ENST00000275884.6
ENST00000475837.1
DENND2A

DENN/MADD domain containing 2A

chr5_-_172662303 1.508 ENST00000517440.1
ENST00000329198.4
NKX2-5

NK2 homeobox 5

chr1_-_161039456 1.477 ENST00000368016.3
ARHGAP30
Rho GTPase activating protein 30
chr2_-_237076992 1.205 ENST00000306318.4
GBX2
gastrulation brain homeobox 2
chr7_-_140341251 1.040 ENST00000491728.1
DENND2A
DENN/MADD domain containing 2A
chr2_-_73511559 1.032 ENST00000521871.1
FBXO41
F-box protein 41
chr21_+_45770009 0.997 ENST00000300482.5
ENST00000431901.1
TRPM2

transient receptor potential cation channel, subfamily M, member 2

chr14_+_69726864 0.958 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr8_+_85097110 0.919 ENST00000517638.1
ENST00000522647.1
RALYL

RALY RNA binding protein-like

chr15_+_73344911 0.885 ENST00000560262.1
ENST00000558964.1
NEO1

neogenin 1

chr14_-_51562745 0.823 ENST00000298355.3
TRIM9
tripartite motif containing 9
chr15_+_84322827 0.817 ENST00000286744.5
ENST00000567476.1
ADAMTSL3

ADAMTS-like 3

chr7_-_558876 0.770 ENST00000354513.5
ENST00000402802.3
PDGFA

platelet-derived growth factor alpha polypeptide

chr14_+_69726968 0.747 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr1_-_205290865 0.728 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr2_-_73511407 0.725 ENST00000520530.2
FBXO41
F-box protein 41
chr5_+_176237478 0.659 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr8_+_104513086 0.620 ENST00000406091.3
RIMS2
regulating synaptic membrane exocytosis 2
chr11_-_65640325 0.618 ENST00000307998.6
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr14_+_100437780 0.612 ENST00000402714.2
EVL
Enah/Vasp-like
chr5_+_63461642 0.595 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180


ring finger protein 180


chr11_-_65640198 0.593 ENST00000528176.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr20_+_61273797 0.544 ENST00000217159.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr20_-_31124186 0.543 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr6_+_35744367 0.542 ENST00000360454.2
ENST00000403376.3
CLPSL2

colipase-like 2

chr4_+_183065793 0.541 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr10_-_62493223 0.541 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_155089251 0.517 ENST00000609974.1
AC144652.1
AC144652.1
chr3_+_54156664 0.495 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr1_+_41707996 0.489 ENST00000425554.1
RP11-399E6.1
RP11-399E6.1
chr17_-_48207115 0.484 ENST00000511964.1
SAMD14
sterile alpha motif domain containing 14
chr7_+_155089486 0.482 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1



insulin induced gene 1



chrX_+_152907913 0.469 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr1_+_44445549 0.465 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr1_+_44445643 0.460 ENST00000309519.7
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr14_+_69726656 0.457 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr13_-_21099935 0.453 ENST00000298248.7
ENST00000382812.1
CRYL1

crystallin, lambda 1

chr12_+_57610562 0.450 ENST00000349394.5
NXPH4
neurexophilin 4
chr1_+_53793885 0.441 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr17_+_78075361 0.438 ENST00000577106.1
ENST00000390015.3
GAA

glucosidase, alpha; acid

chr7_-_559853 0.434 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr7_+_130131907 0.432 ENST00000223215.4
ENST00000437945.1
MEST

mesoderm specific transcript

chr19_+_8274204 0.431 ENST00000561053.1
ENST00000251363.5
ENST00000559450.1
ENST00000559336.1
CERS4



ceramide synthase 4



chr5_+_156693091 0.428 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2



cytoplasmic FMR1 interacting protein 2



chr6_+_151646800 0.427 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr13_+_52158610 0.421 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr21_-_42219065 0.421 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr15_-_90645679 0.419 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2


isocitrate dehydrogenase 2 (NADP+), mitochondrial


chr20_+_6748311 0.418 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr19_+_8274185 0.417 ENST00000558268.1
ENST00000558331.1
CERS4

ceramide synthase 4

chr1_+_210502238 0.414 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
HHAT





hedgehog acyltransferase





chr20_-_43280325 0.397 ENST00000537820.1
ADA
adenosine deaminase
chr16_-_54963026 0.394 ENST00000560208.1
ENST00000557792.1
CRNDE

colorectal neoplasia differentially expressed (non-protein coding)

chr17_+_78075324 0.394 ENST00000570803.1
GAA
glucosidase, alpha; acid
chr13_-_31039375 0.393 ENST00000399494.1
HMGB1
high mobility group box 1
chr3_-_47823298 0.387 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr2_-_200715573 0.382 ENST00000420922.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr11_+_61522844 0.381 ENST00000265460.5
MYRF
myelin regulatory factor
chr17_+_5973793 0.381 ENST00000317744.5
WSCD1
WSC domain containing 1
chr9_-_107754034 0.377 ENST00000457720.1
RP11-217B7.3
RP11-217B7.3
chrX_-_50557014 0.376 ENST00000376020.2
SHROOM4
shroom family member 4
chr17_+_78075498 0.373 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr8_+_104384616 0.372 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr16_+_66638003 0.371 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3





CKLF-like MARVEL transmembrane domain containing 3





chr19_+_49622646 0.371 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr16_+_66638616 0.371 ENST00000564060.1
ENST00000565922.1
CMTM3

CKLF-like MARVEL transmembrane domain containing 3

chr17_+_7348658 0.368 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
CHRNB1


cholinergic receptor, nicotinic, beta 1 (muscle)


chr1_-_45672221 0.367 ENST00000359600.5
ZSWIM5
zinc finger, SWIM-type containing 5
chr3_+_54156570 0.366 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr2_+_232575168 0.366 ENST00000440384.1
PTMA
prothymosin, alpha
chr22_+_24115000 0.365 ENST00000215743.3
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr6_+_12012170 0.355 ENST00000487103.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr12_+_54379569 0.343 ENST00000513209.1
RP11-834C11.12
RP11-834C11.12
chr11_+_86748863 0.343 ENST00000340353.7
TMEM135
transmembrane protein 135
chr11_+_86749035 0.343 ENST00000305494.5
ENST00000535167.1
TMEM135

transmembrane protein 135

chr2_-_73053126 0.336 ENST00000272427.6
ENST00000410104.1
EXOC6B

exocyst complex component 6B

chr17_-_42402138 0.332 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
SLC25A39









solute carrier family 25, member 39









chr11_+_86748957 0.330 ENST00000526733.1
ENST00000532959.1
TMEM135

transmembrane protein 135

chr5_+_156693159 0.328 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr20_+_35201857 0.318 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr17_+_7348374 0.316 ENST00000306071.2
ENST00000572857.1
CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

chr18_-_22804637 0.315 ENST00000577775.1
ZNF521
zinc finger protein 521
chr12_+_122064673 0.314 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr13_+_42031679 0.309 ENST00000379359.3
RGCC
regulator of cell cycle
chr18_+_12093838 0.308 ENST00000587848.2
ANKRD62
ankyrin repeat domain 62
chr1_-_63153944 0.303 ENST00000340370.5
ENST00000404627.2
ENST00000251157.5
DOCK7


dedicator of cytokinesis 7


chr12_+_49932886 0.303 ENST00000257981.6
KCNH3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr2_-_200715834 0.303 ENST00000420128.1
ENST00000416668.1
FTCDNL1

formiminotransferase cyclodeaminase N-terminal like

chr12_+_122064398 0.303 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr1_-_231004220 0.302 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr11_-_67397371 0.301 ENST00000376693.2
ENST00000301490.4
NUDT8

nudix (nucleoside diphosphate linked moiety X)-type motif 8

chr17_-_3867585 0.298 ENST00000359983.3
ENST00000352011.3
ENST00000397043.3
ENST00000397041.3
ENST00000397035.3
ENST00000397039.1
ENST00000309890.7
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr6_-_35109145 0.298 ENST00000373974.4
ENST00000244645.3
TCP11

t-complex 11, testis-specific

chr10_-_79397202 0.298 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1


potassium large conductance calcium-activated channel, subfamily M, alpha member 1


chr13_-_45915221 0.297 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1




tumor protein, translationally-controlled 1




chr13_+_76123883 0.295 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr17_+_5973740 0.295 ENST00000576083.1
WSCD1
WSC domain containing 1
chrX_-_140271249 0.291 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr3_-_127541679 0.290 ENST00000265052.5
MGLL
monoglyceride lipase
chr20_+_35201993 0.286 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr12_+_93965451 0.284 ENST00000548537.1
SOCS2
suppressor of cytokine signaling 2
chrX_-_9734004 0.284 ENST00000467482.1
ENST00000380929.2
GPR143

G protein-coupled receptor 143

chr12_+_93964746 0.281 ENST00000536696.2
SOCS2
suppressor of cytokine signaling 2
chr3_+_152552685 0.280 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr10_-_79397391 0.279 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr13_+_27825706 0.275 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21


ribosomal protein L21


chr1_+_201617450 0.273 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1


neuron navigator 1


chr1_-_92949505 0.271 ENST00000370332.1
GFI1
growth factor independent 1 transcription repressor
chr17_-_80656528 0.270 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B


RAB40B, member RAS oncogene family


chr10_+_104474353 0.262 ENST00000602647.1
ENST00000602439.1
ENST00000602764.1
SFXN2


sideroflexin 2


chr10_-_99094458 0.261 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr1_-_31196427 0.258 ENST00000373765.4
MATN1
matrilin 1, cartilage matrix protein
chr15_+_101459420 0.256 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1



leucine-rich repeat kinase 1



chr14_+_100070869 0.256 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr14_-_91526462 0.251 ENST00000536315.2
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr16_-_88717423 0.249 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA


cytochrome b-245, alpha polypeptide


chr10_+_104474207 0.249 ENST00000602831.1
ENST00000369893.5
SFXN2

sideroflexin 2

chr1_+_26126667 0.246 ENST00000361547.2
ENST00000354177.4
ENST00000374315.1
SEPN1


selenoprotein N, 1


chr2_-_73520667 0.243 ENST00000545030.1
ENST00000436467.2
EGR4

early growth response 4

chr14_-_91526922 0.239 ENST00000418736.2
ENST00000261991.3
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr13_-_102068706 0.237 ENST00000251127.6
NALCN
sodium leak channel, non-selective
chr12_-_122238464 0.236 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr1_-_117210290 0.236 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chr13_+_27998681 0.235 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr2_+_74881355 0.234 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr2_-_25142708 0.234 ENST00000260600.5
ENST00000435135.1
ADCY3

adenylate cyclase 3

chr9_+_96338860 0.233 ENST00000375376.4
PHF2
PHD finger protein 2
chr1_+_44444865 0.233 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr16_-_87729753 0.232 ENST00000538868.1
AC010536.1
Uncharacterized protein; cDNA FLJ45526 fis, clone BRTHA2027227
chr10_-_79397316 0.230 ENST00000372421.5
ENST00000457953.1
KCNMA1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

chr1_-_98386543 0.228 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
DPYD


dihydropyrimidine dehydrogenase


chr3_-_71802760 0.228 ENST00000295612.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr4_-_185655212 0.226 ENST00000541971.1
MLF1IP
centromere protein U
chrX_-_50557302 0.225 ENST00000289292.7
SHROOM4
shroom family member 4
chr7_+_130126165 0.225 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr1_-_45805607 0.224 ENST00000372104.1
ENST00000448481.1
ENST00000483127.1
ENST00000528013.2
ENST00000456914.2
MUTYH




mutY homolog




chr9_-_126030817 0.223 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP


spermatid perinuclear RNA binding protein


chr13_+_103249322 0.223 ENST00000376065.4
ENST00000376052.3
TPP2

tripeptidyl peptidase II

chr15_-_66084428 0.222 ENST00000443035.3
ENST00000431932.2
DENND4A

DENN/MADD domain containing 4A

chr22_-_31503490 0.222 ENST00000400299.2
SELM
Selenoprotein M
chr18_+_6729725 0.221 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28


Rho GTPase activating protein 28


chr2_-_100106419 0.221 ENST00000393445.3
ENST00000258428.3
REV1

REV1, polymerase (DNA directed)

chr18_-_72920372 0.221 ENST00000581620.1
ENST00000582437.1
ZADH2

zinc binding alcohol dehydrogenase domain containing 2

chr15_+_76135622 0.221 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2


ubiquitin-conjugating enzyme E2Q family member 2


chr4_-_185655278 0.220 ENST00000281453.5
MLF1IP
centromere protein U
chr15_-_66084621 0.220 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr15_-_60771280 0.218 ENST00000560072.1
ENST00000560406.1
ENST00000560520.1
ENST00000261520.4
ENST00000439632.1
NARG2




NMDA receptor regulated 2




chr1_-_45805667 0.215 ENST00000488731.2
ENST00000435155.1
MUTYH

mutY homolog

chr11_+_46354455 0.215 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr17_-_79791118 0.214 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
FAM195B





family with sequence similarity 195, member B





chr2_-_70529180 0.214 ENST00000450256.1
ENST00000037869.3
FAM136A

family with sequence similarity 136, member A

chr18_+_6729698 0.214 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr14_+_94577074 0.213 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27








interferon, alpha-inducible protein 27








chr6_+_143771934 0.212 ENST00000367592.1
PEX3
peroxisomal biogenesis factor 3
chr1_-_41707778 0.211 ENST00000337495.5
ENST00000372597.1
ENST00000372596.1
SCMH1


sex comb on midleg homolog 1 (Drosophila)


chr15_-_60771128 0.211 ENST00000558512.1
ENST00000561114.1
NARG2

NMDA receptor regulated 2

chrX_+_21959108 0.209 ENST00000457085.1
SMS
spermine synthase
chr17_+_74381343 0.209 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr16_+_87636474 0.209 ENST00000284262.2
JPH3
junctophilin 3
chr3_-_15643060 0.208 ENST00000414979.1
ENST00000435217.2
ENST00000456194.2
ENST00000457447.2
HACL1



2-hydroxyacyl-CoA lyase 1



chr3_-_52001448 0.206 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chr3_-_48471454 0.205 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr3_-_15643090 0.205 ENST00000451445.2
ENST00000421993.1
HACL1

2-hydroxyacyl-CoA lyase 1

chr3_-_133969437 0.204 ENST00000460933.1
ENST00000296084.4
RYK

receptor-like tyrosine kinase

chr3_-_127542021 0.204 ENST00000434178.2
MGLL
monoglyceride lipase
chr2_-_70529126 0.203 ENST00000438759.1
ENST00000430566.1
FAM136A

family with sequence similarity 136, member A

chr16_-_4466622 0.203 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
CORO7





coronin 7





chr6_+_143772060 0.202 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr17_-_2206801 0.200 ENST00000544865.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr6_-_105850937 0.199 ENST00000369110.3
PREP
prolyl endopeptidase
chr15_+_79165296 0.195 ENST00000558746.1
ENST00000558830.1
ENST00000559345.1
MORF4L1


mortality factor 4 like 1


chr3_-_127542051 0.195 ENST00000398104.1
MGLL
monoglyceride lipase
chr16_-_46865286 0.195 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr6_-_143266297 0.194 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr6_+_111279763 0.194 ENST00000329970.7
GTF3C6
general transcription factor IIIC, polypeptide 6, alpha 35kDa
chr12_+_121416489 0.193 ENST00000541395.1
ENST00000544413.1
HNF1A

HNF1 homeobox A

chr15_+_79165372 0.192 ENST00000558502.1
MORF4L1
mortality factor 4 like 1
chr9_+_36136700 0.192 ENST00000396613.3
ENST00000377959.1
ENST00000377960.4
GLIPR2


GLI pathogenesis-related 2


chr19_-_18902106 0.191 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
COMP


cartilage oligomeric matrix protein


chr8_-_102218292 0.191 ENST00000518336.1
ENST00000520454.1
ZNF706

zinc finger protein 706

chr16_-_4466565 0.190 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7


CORO7-PAM16 readthrough
coronin 7


chr13_-_39611956 0.190 ENST00000418503.1
PROSER1
proline and serine rich 1
chr19_-_3478477 0.190 ENST00000591708.1
C19orf77
chromosome 19 open reading frame 77
chr13_+_98795664 0.189 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_-_64246206 0.188 ENST00000409558.4
ENST00000272322.4
VPS54

vacuolar protein sorting 54 homolog (S. cerevisiae)

chr18_+_74207477 0.188 ENST00000532511.1
RP11-17M16.1
uncharacterized protein LOC400658
chr11_+_8704298 0.187 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
RPL27A



ribosomal protein L27a



chr17_-_43339474 0.187 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr3_+_134205000 0.186 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
CEP63


centrosomal protein 63kDa


chr6_-_84937314 0.186 ENST00000257766.4
ENST00000403245.3
KIAA1009

KIAA1009

chr9_+_133971909 0.186 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L



allograft inflammatory factor 1-like



chr15_-_32162833 0.185 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr15_-_55790515 0.184 ENST00000448430.2
ENST00000457155.2
DYX1C1

dyslexia susceptibility 1 candidate 1

chr2_+_70314579 0.184 ENST00000303577.5
PCBP1
poly(rC) binding protein 1
chr16_+_84733575 0.184 ENST00000219473.7
ENST00000563892.1
ENST00000562283.1
ENST00000570191.1
ENST00000569038.1
ENST00000570053.1
USP10





ubiquitin specific peptidase 10





chr19_-_14316980 0.183 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr22_-_28197486 0.183 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr15_-_56285742 0.182 ENST00000435532.3
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0060929 Purkinje myocyte differentiation(GO:0003168) septum secundum development(GO:0003285) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.4 1.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.2 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.2 0.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.2 1.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 1.2 GO:0021546 rhombomere development(GO:0021546)
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.6 GO:0046102 inosine metabolic process(GO:0046102)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0035623 renal glucose absorption(GO:0035623)
0.1 0.3 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.3 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.3 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.2 GO:2000738 positive regulation of stem cell differentiation(GO:2000738)
0.1 0.2 GO:0060351 growth plate cartilage development(GO:0003417) cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.9 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 1.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.7 GO:0045007 depurination(GO:0045007)
0.1 0.5 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.5 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.1 0.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.5 GO:0051167 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.2 GO:0008355 olfactory learning(GO:0008355)
0.1 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.0 0.7 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.0 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.4 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.3 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 1.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.3 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:1904044 peptidyl-serine ADP-ribosylation(GO:0018312) response to aldosterone(GO:1904044)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 1.5 GO:0032094 response to food(GO:0032094)
0.0 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.0 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.3 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.4 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.0 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.0 GO:0060648 mammary gland specification(GO:0060594) mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.4 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.3 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.0 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.0 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.4 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.0 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0035933 glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849)
0.0 0.2 GO:0006954 inflammatory response(GO:0006954)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 0.4 GO:1990742 microvesicle(GO:1990742)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.3 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.0 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 1.5 GO:0010736 serum response element binding(GO:0010736)
0.2 1.2 GO:0004461 lactose synthase activity(GO:0004461)
0.2 0.7 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.4 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 0.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.5 GO:0008047 enzyme activator activity(GO:0008047)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 1.2 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0097604 temperature-gated ion channel activity(GO:0097603) temperature-gated cation channel activity(GO:0097604) mechanically-gated potassium channel activity(GO:0098782)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 2.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.2 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.3 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.1 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 1.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 4.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation