Motif ID: GRHL1

Z-value: 0.246


Transcription factors associated with GRHL1:

Gene SymbolEntrez IDGene Name
GRHL1 ENSG00000134317.13 GRHL1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GRHL1hg19_v2_chr2_+_10091815_100918640.551.2e-01Click!


Activity profile for motif GRHL1.

activity profile for motif GRHL1


Sorted Z-values histogram for motif GRHL1

Sorted Z-values for motif GRHL1



Network of associatons between targets according to the STRING database.



First level regulatory network of GRHL1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_140122018 0.245 ENST00000445101.2
 RNF224
ring finger protein 224
chr3_-_172241250 0.239 ENST00000420541.2
ENST00000241261.2
 TNFSF10

tumor necrosis factor (ligand) superfamily, member 10

chr6_-_46889694 0.211 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
 GPR116


G protein-coupled receptor 116


chr15_+_94774767 0.188 ENST00000543482.1
 MCTP2
multiple C2 domains, transmembrane 2
chr2_-_190446738 0.178 ENST00000427419.1
ENST00000455320.1
 SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

chr2_+_95940220 0.158 ENST00000542147.1
 PROM2
prominin 2
chr7_-_80551671 0.123 ENST00000419255.2
ENST00000544525.1
 SEMA3C

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

chr18_-_35145689 0.100 ENST00000591287.1
ENST00000601019.1
ENST00000601392.1
 CELF4


CUGBP, Elav-like family member 4


chr18_-_35145593 0.095 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
 CELF4


CUGBP, Elav-like family member 4


chr20_-_18038521 0.095 ENST00000278780.6
 OVOL2
ovo-like zinc finger 2
chr14_-_24732738 0.091 ENST00000558074.1
ENST00000560226.1
 TGM1

transglutaminase 1

chr2_+_95940186 0.081 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
 PROM2


prominin 2


chr6_-_31107127 0.080 ENST00000259845.4
 PSORS1C2
psoriasis susceptibility 1 candidate 2
chr11_+_76493294 0.079 ENST00000533752.1
 TSKU
tsukushi, small leucine rich proteoglycan
chr18_-_35145728 0.078 ENST00000361795.5
ENST00000603232.1
 CELF4

CUGBP, Elav-like family member 4

chr18_-_35145981 0.077 ENST00000420428.2
ENST00000412753.1
 CELF4

CUGBP, Elav-like family member 4

chr1_-_24469602 0.077 ENST00000270800.1
 IL22RA1
interleukin 22 receptor, alpha 1
chr5_+_125758865 0.072 ENST00000542322.1
ENST00000544396.1
 GRAMD3

GRAM domain containing 3

chr5_+_125758813 0.068 ENST00000285689.3
ENST00000515200.1
 GRAMD3

GRAM domain containing 3

chr5_-_132299290 0.066 ENST00000378595.3
 AFF4
AF4/FMR2 family, member 4
chr14_-_62217779 0.066 ENST00000554254.1
 HIF1A-AS2
HIF1A antisense RNA 2
chr6_+_32121218 0.064 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
 PPT2


palmitoyl-protein thioesterase 2


chr5_+_125759140 0.061 ENST00000543198.1
 GRAMD3
GRAM domain containing 3
chr4_-_110736505 0.056 ENST00000609440.1
 RP11-602N24.3
RP11-602N24.3
chr7_-_138794081 0.052 ENST00000464606.1
 ZC3HAV1
zinc finger CCCH-type, antiviral 1
chr5_-_132299313 0.052 ENST00000265343.5
 AFF4
AF4/FMR2 family, member 4
chr2_-_209118974 0.049 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
 IDH1


isocitrate dehydrogenase 1 (NADP+), soluble


chr11_+_706595 0.046 ENST00000531348.1
ENST00000530636.1
 EPS8L2

EPS8-like 2

chr19_-_12405606 0.045 ENST00000356109.5
 ZNF44
zinc finger protein 44
chr4_+_26859300 0.045 ENST00000494628.2
 STIM2
stromal interaction molecule 2
chr19_-_12405689 0.043 ENST00000355684.5
 ZNF44
zinc finger protein 44
chr20_-_25320367 0.042 ENST00000450393.1
ENST00000491682.1
 ABHD12

abhydrolase domain containing 12

chr19_+_12035913 0.035 ENST00000591944.1
 ZNF763
Uncharacterized protein; Zinc finger protein 763
chr9_-_77703115 0.034 ENST00000361092.4
ENST00000376808.4
 NMRK1

nicotinamide riboside kinase 1

chr5_+_134303591 0.033 ENST00000282611.6
 CATSPER3
cation channel, sperm associated 3
chr8_-_130799134 0.029 ENST00000276708.4
 GSDMC
gasdermin C
chr17_-_60883993 0.028 ENST00000583803.1
ENST00000456609.2
 MARCH10

membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase

chr19_-_35981358 0.027 ENST00000484218.2
ENST00000338897.3
 KRTDAP

keratinocyte differentiation-associated protein

chr19_-_12146483 0.027 ENST00000455504.2
ENST00000547560.1
ENST00000552904.1
ENST00000419886.2
ENST00000550507.1
ENST00000344980.6
ENST00000550745.1
ENST00000411841.1
 ZNF433







zinc finger protein 433







chr8_+_27950619 0.027 ENST00000542181.1
ENST00000524103.1
ENST00000537665.1
ENST00000380353.4
ENST00000520288.1
 ELP3




elongator acetyltransferase complex subunit 3




chr19_+_58038683 0.024 ENST00000240719.3
ENST00000376233.3
ENST00000594943.1
ENST00000602149.1
 ZNF549



zinc finger protein 549



chr12_+_49687425 0.021 ENST00000257860.4
 PRPH
peripherin
chr1_+_44440575 0.019 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
 ATP6V0B


ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b


chr1_-_28384598 0.018 ENST00000373864.1
 EYA3
eyes absent homolog 3 (Drosophila)
chr4_+_110736659 0.016 ENST00000394631.3
ENST00000226796.6
 GAR1

GAR1 ribonucleoprotein

chr1_-_36863481 0.016 ENST00000315732.2
 LSM10
LSM10, U7 small nuclear RNA associated
chr19_+_12035878 0.015 ENST00000254321.5
ENST00000538752.1
ENST00000590798.1
 ZNF700
ZNF763
ZNF763
zinc finger protein 700
zinc finger protein 763
Uncharacterized protein; Zinc finger protein 763
chr4_-_99850243 0.014 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
 EIF4E



eukaryotic translation initiation factor 4E



chr19_+_19496728 0.014 ENST00000537887.1
ENST00000417582.2
 GATAD2A

GATA zinc finger domain containing 2A

chr19_-_40596767 0.011 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
 ZNF780A


zinc finger protein 780A


chr16_+_2564254 0.009 ENST00000565223.1
 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr6_-_43027105 0.008 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
 MRPL2



mitochondrial ribosomal protein L2



chr19_+_19496624 0.006 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
 GATAD2A


GATA zinc finger domain containing 2A


chr9_+_130565487 0.006 ENST00000373225.3
ENST00000431857.1
 FPGS

folylpolyglutamate synthase

chr14_-_23540826 0.006 ENST00000357481.2
 ACIN1
apoptotic chromatin condensation inducer 1
chr2_+_113299990 0.006 ENST00000537335.1
ENST00000417433.2
 POLR1B

polymerase (RNA) I polypeptide B, 128kDa

chr14_+_23938891 0.005 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
 NGDN


neuroguidin, EIF4E binding protein


chr19_-_11849697 0.005 ENST00000586121.1
ENST00000431998.1
ENST00000341191.6
ENST00000545749.1
ENST00000440527.1
 ZNF823




zinc finger protein 823




chr9_+_130565568 0.004 ENST00000423577.1
 FPGS
folylpolyglutamate synthase
chr8_+_22601 0.004 ENST00000522481.3
ENST00000518652.1
 AC144568.2

Uncharacterized protein

chr1_+_244515930 0.004 ENST00000366537.1
ENST00000308105.4
 C1orf100

chromosome 1 open reading frame 100

chr9_+_104161123 0.004 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
 ZNF189


zinc finger protein 189


chr19_-_4043154 0.003 ENST00000535853.1
 AC016586.1
AC016586.1
chr1_-_234667504 0.003 ENST00000421207.1
ENST00000435574.1
 RP5-855F14.1

RP5-855F14.1

chr4_+_156588249 0.002 ENST00000393832.3
 GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr7_+_76139925 0.001 ENST00000394849.1
 UPK3B
uroplakin 3B
chr3_+_186383741 0.001 ENST00000232003.4
 HRG
histidine-rich glycoprotein
chr1_+_40723779 0.001 ENST00000372759.3
 ZMPSTE24
zinc metallopeptidase STE24
chr1_-_52520828 0.001 ENST00000610127.1
 TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr18_+_20494078 0.000 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
 RBBP8



retinoblastoma binding protein 8



chr11_+_15095108 0.000 ENST00000324229.6
ENST00000533448.1
 CALCB

calcitonin-related polypeptide beta


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0044393 microspike(GO:0044393)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0042835 BRE binding(GO:0042835)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)