Motif ID: GLIS2

Z-value: 0.475


Transcription factors associated with GLIS2:

Gene SymbolEntrez IDGene Name
GLIS2 ENSG00000126603.4 GLIS2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GLIS2hg19_v2_chr16_+_4364762_43647620.781.4e-02Click!


Activity profile for motif GLIS2.

activity profile for motif GLIS2


Sorted Z-values histogram for motif GLIS2

Sorted Z-values for motif GLIS2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLIS2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_37571717 0.879 ENST00000338415.3
ENST00000404976.1
QPCT

glutaminyl-peptide cyclotransferase

chr19_+_50979753 0.868 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
EMC10



ER membrane protein complex subunit 10



chr19_-_50979981 0.828 ENST00000595790.1
ENST00000600100.1
FAM71E1

family with sequence similarity 71, member E1

chr5_+_140566 0.766 ENST00000502646.1
PLEKHG4B
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr11_+_68451943 0.677 ENST00000265643.3
GAL
galanin/GMAP prepropeptide
chr2_+_24272576 0.672 ENST00000380986.4
ENST00000452109.1
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr2_+_37571845 0.575 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chrX_-_102319092 0.515 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr6_-_32908792 0.466 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_+_24272543 0.464 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr14_-_54418598 0.431 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr2_-_27718052 0.429 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chrX_+_51927919 0.387 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr12_-_96184913 0.321 ENST00000538383.1
NTN4
netrin 4
chr1_-_156675564 0.297 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr1_-_22215192 0.293 ENST00000374673.3
HSPG2
heparan sulfate proteoglycan 2
chr9_+_135037334 0.292 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2



netrin G2



chr14_-_105635090 0.276 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr1_-_156675368 0.272 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr5_+_68788594 0.271 ENST00000396442.2
ENST00000380766.2
OCLN

occludin

chr6_+_33048222 0.265 ENST00000428835.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr1_-_31661000 0.263 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1


Na+/K+ transporting ATPase interacting 1


chr2_+_149895207 0.260 ENST00000409876.1
LYPD6B
LY6/PLAUR domain containing 6B
chr12_-_95942563 0.246 ENST00000549639.1
ENST00000551837.1
USP44

ubiquitin specific peptidase 44

chr6_+_69345166 0.234 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr1_-_156675535 0.233 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr12_-_95942613 0.232 ENST00000393091.2
USP44
ubiquitin specific peptidase 44
chr8_+_98881268 0.229 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2


matrilin 2


chr11_+_121447469 0.225 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr16_+_811073 0.221 ENST00000382862.3
ENST00000563651.1
MSLN

mesothelin

chr2_-_230933709 0.205 ENST00000436869.1
ENST00000295190.4
SLC16A14

solute carrier family 16, member 14

chr2_-_230933623 0.194 ENST00000457406.1
SLC16A14
solute carrier family 16, member 14
chr16_+_32264040 0.193 ENST00000398664.3
TP53TG3D
TP53 target 3D
chrX_-_48823165 0.189 ENST00000419374.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr16_-_68269971 0.189 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr15_+_69307028 0.187 ENST00000388866.3
ENST00000530406.2
NOX5

NADPH oxidase, EF-hand calcium binding domain 5

chr20_-_30310656 0.186 ENST00000376055.4
BCL2L1
BCL2-like 1
chr8_-_11325047 0.182 ENST00000531804.1
FAM167A
family with sequence similarity 167, member A
chr13_-_20767037 0.181 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chrX_-_8700171 0.177 ENST00000262648.3
KAL1
Kallmann syndrome 1 sequence
chr5_+_169659950 0.174 ENST00000593851.1
C5orf58
chromosome 5 open reading frame 58
chr19_-_5292781 0.171 ENST00000586065.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr17_-_5015129 0.170 ENST00000575898.1
ENST00000416429.2
ZNF232

zinc finger protein 232

chr3_+_183903811 0.169 ENST00000429586.2
ENST00000292808.5
ABCF3

ATP-binding cassette, sub-family F (GCN20), member 3

chr2_+_48757278 0.168 ENST00000404752.1
ENST00000406226.1
STON1

stonin 1

chr1_+_43637996 0.166 ENST00000528956.1
ENST00000529956.1
WDR65

WD repeat domain 65

chr12_-_53242770 0.164 ENST00000304620.4
ENST00000547110.1
KRT78

keratin 78

chr1_-_23810664 0.164 ENST00000336689.3
ENST00000437606.2
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr1_-_92371839 0.163 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr17_+_18625336 0.161 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L




tripartite motif containing 16-like




chr9_+_127539481 0.161 ENST00000373580.3
OLFML2A
olfactomedin-like 2A
chr8_+_1772132 0.154 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
ARHGEF10



Rho guanine nucleotide exchange factor (GEF) 10



chr8_-_29120580 0.152 ENST00000524189.1
KIF13B
kinesin family member 13B
chr15_-_96590126 0.151 ENST00000561051.1
RP11-4G2.1
RP11-4G2.1
chr12_-_95941987 0.148 ENST00000537435.2
USP44
ubiquitin specific peptidase 44
chr3_+_44626446 0.146 ENST00000441021.1
ENST00000322734.2
ZNF660

zinc finger protein 660

chr20_-_30310693 0.145 ENST00000307677.4
ENST00000420653.1
BCL2L1

BCL2-like 1

chr8_-_29120604 0.145 ENST00000521515.1
KIF13B
kinesin family member 13B
chr12_-_111127201 0.144 ENST00000548312.1
HVCN1
hydrogen voltage-gated channel 1
chr22_-_38484922 0.143 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr2_+_114737472 0.137 ENST00000420161.1
AC110769.3
AC110769.3
chrX_+_153656978 0.136 ENST00000369762.2
ENST00000422890.1
ATP6AP1

ATPase, H+ transporting, lysosomal accessory protein 1

chr1_+_201979743 0.136 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr4_-_48082192 0.133 ENST00000507351.1
TXK
TXK tyrosine kinase
chr18_+_32073839 0.132 ENST00000590412.1
DTNA
dystrobrevin, alpha
chr3_+_180630444 0.130 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
FXR1



fragile X mental retardation, autosomal homolog 1



chr1_+_201979645 0.129 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr20_-_30310797 0.129 ENST00000422920.1
BCL2L1
BCL2-like 1
chr2_-_179343226 0.127 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr17_+_41476327 0.126 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr22_+_23264766 0.124 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr19_-_5340730 0.123 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr2_-_179343268 0.123 ENST00000424785.2
FKBP7
FK506 binding protein 7
chr11_+_826136 0.122 ENST00000528315.1
ENST00000533803.1
EFCAB4A

EF-hand calcium binding domain 4A

chr12_+_52626898 0.121 ENST00000331817.5
KRT7
keratin 7
chr9_+_97766469 0.120 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr5_+_172484377 0.119 ENST00000523161.1
CREBRF
CREB3 regulatory factor
chr11_+_827248 0.118 ENST00000527089.1
ENST00000530183.1
EFCAB4A

EF-hand calcium binding domain 4A

chr10_+_133918175 0.117 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr2_-_157186630 0.116 ENST00000406048.2
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr19_+_17858509 0.115 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1


FCH domain only 1


chr2_-_55277654 0.112 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4


reticulon 4


chr9_+_97766409 0.112 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr2_-_55277512 0.110 ENST00000402434.2
RTN4
reticulon 4
chr22_+_17082732 0.109 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1





transmembrane phosphatase with tensin homology pseudogene 1





chr2_-_55277692 0.109 ENST00000394611.2
RTN4
reticulon 4
chr1_+_150954493 0.106 ENST00000368947.4
ANXA9
annexin A9
chr9_+_19230433 0.103 ENST00000434457.2
ENST00000602925.1
DENND4C

DENN/MADD domain containing 4C

chr12_+_57522692 0.103 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr7_+_87257701 0.102 ENST00000338056.3
ENST00000493037.1
RUNDC3B

RUN domain containing 3B

chrX_-_153744434 0.100 ENST00000369643.1
ENST00000393572.1
FAM3A

family with sequence similarity 3, member A

chr19_+_51293672 0.100 ENST00000270593.1
ENST00000270594.3
ACPT

acid phosphatase, testicular

chr6_-_119670919 0.099 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr16_+_2521500 0.099 ENST00000293973.1
NTN3
netrin 3
chr1_-_186649543 0.097 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_27467418 0.096 ENST00000528564.1
MYO18A
myosin XVIIIA
chrX_-_2418936 0.096 ENST00000412516.2
ENST00000334651.5
ENST00000461691.1
ENST00000381223.4
ENST00000381222.2
DHRSX

ZBED1


dehydrogenase/reductase (SDR family) X-linked

zinc finger, BED-type containing 1


chr5_+_102090974 0.094 ENST00000512073.1
PAM
peptidylglycine alpha-amidating monooxygenase
chrX_+_148793714 0.093 ENST00000355220.5
MAGEA11
melanoma antigen family A, 11
chr19_-_39303576 0.093 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr19_-_46405861 0.091 ENST00000322217.5
MYPOP
Myb-related transcription factor, partner of profilin
chr19_+_16999966 0.091 ENST00000599210.1
F2RL3
coagulation factor II (thrombin) receptor-like 3
chrX_+_53078273 0.090 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr1_-_1142067 0.090 ENST00000379268.2
TNFRSF18
tumor necrosis factor receptor superfamily, member 18
chr12_+_57522258 0.090 ENST00000553277.1
ENST00000243077.3
LRP1

low density lipoprotein receptor-related protein 1

chr19_+_56159421 0.089 ENST00000587213.1
CCDC106
coiled-coil domain containing 106
chr2_+_242716231 0.089 ENST00000192314.6
GAL3ST2
galactose-3-O-sulfotransferase 2
chr10_+_134000404 0.088 ENST00000338492.4
ENST00000368629.1
DPYSL4

dihydropyrimidinase-like 4

chr2_-_219154715 0.088 ENST00000451181.1
ENST00000429501.1
TMBIM1

transmembrane BAX inhibitor motif containing 1

chrX_+_51636629 0.087 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1


melanoma antigen family D, 1


chr10_-_14880566 0.087 ENST00000378442.1
CDNF
cerebral dopamine neurotrophic factor
chr17_+_47572647 0.085 ENST00000172229.3
NGFR
nerve growth factor receptor
chr7_+_29237354 0.084 ENST00000546235.1
CHN2
chimerin 2
chr7_+_87257854 0.084 ENST00000394654.3
RUNDC3B
RUN domain containing 3B
chr7_+_133812052 0.083 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr19_+_17186577 0.083 ENST00000595618.1
ENST00000594824.1
MYO9B

myosin IXB

chr17_+_30348024 0.082 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
LRRC37B



leucine rich repeat containing 37B



chrX_-_10557949 0.082 ENST00000380780.1
MID1
midline 1 (Opitz/BBB syndrome)
chr19_+_56159509 0.082 ENST00000586790.1
ENST00000591578.1
ENST00000588740.1
CCDC106


coiled-coil domain containing 106


chrX_+_54834159 0.081 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2


melanoma antigen family D, 2


chr3_+_184038073 0.081 ENST00000428387.1
ENST00000434061.2
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr11_+_1244288 0.081 ENST00000529681.1
ENST00000447027.1
MUC5B

mucin 5B, oligomeric mucus/gel-forming

chrX_+_54834004 0.081 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chr1_-_16939976 0.080 ENST00000430580.2
NBPF1
neuroblastoma breakpoint family, member 1
chrX_-_153744507 0.080 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
FAM3A





family with sequence similarity 3, member A





chr16_+_27078219 0.080 ENST00000418886.1
C16orf82
chromosome 16 open reading frame 82
chr3_+_184038234 0.080 ENST00000427607.1
ENST00000457456.1
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr7_-_73133959 0.078 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A



syntaxin 1A (brain)



chr8_+_41347915 0.078 ENST00000518270.1
ENST00000520817.1
GOLGA7

golgin A7

chr2_+_181845074 0.077 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
UBE2E3



ubiquitin-conjugating enzyme E2E 3



chr14_-_105531759 0.077 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
GPR132


G protein-coupled receptor 132


chr5_-_159739483 0.076 ENST00000519673.1
ENST00000541762.1
CCNJL

cyclin J-like

chr17_-_45056606 0.076 ENST00000322329.3
RPRML
reprimo-like
chr16_-_32688053 0.075 ENST00000398682.4
TP53TG3
TP53 target 3
chr19_-_36643329 0.075 ENST00000589154.1
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr19_+_11909329 0.074 ENST00000323169.5
ENST00000450087.1
ZNF491

zinc finger protein 491

chr19_+_54369434 0.074 ENST00000421337.1
MYADM
myeloid-associated differentiation marker
chr17_-_38020392 0.073 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3







IKAROS family zinc finger 3 (Aiolos)







chr19_+_56159362 0.072 ENST00000593069.1
ENST00000308964.3
CCDC106

coiled-coil domain containing 106

chr6_+_163148161 0.071 ENST00000337019.3
ENST00000366889.2
PACRG

PARK2 co-regulated

chr17_-_76921459 0.071 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr10_+_43633914 0.071 ENST00000374466.3
ENST00000374464.1
CSGALNACT2

chondroitin sulfate N-acetylgalactosaminyltransferase 2

chrX_+_53449839 0.071 ENST00000457095.1
RIBC1
RIB43A domain with coiled-coils 1
chr11_-_64510409 0.070 ENST00000394429.1
ENST00000394428.1
RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

chr6_+_43457317 0.070 ENST00000438588.2
TJAP1
tight junction associated protein 1 (peripheral)
chr19_+_54372693 0.069 ENST00000391768.2
MYADM
myeloid-associated differentiation marker
chr17_+_38498594 0.068 ENST00000394081.3
RARA
retinoic acid receptor, alpha
chr19_+_54372639 0.067 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chr20_+_33814457 0.067 ENST00000246186.6
MMP24
matrix metallopeptidase 24 (membrane-inserted)
chr6_+_31926857 0.065 ENST00000375394.2
ENST00000544581.1
SKIV2L

superkiller viralicidic activity 2-like (S. cerevisiae)

chr14_-_76447336 0.064 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr20_-_30433396 0.064 ENST00000375978.3
FOXS1
forkhead box S1
chr17_-_38020379 0.062 ENST00000351680.3
ENST00000346243.3
ENST00000350532.3
ENST00000467757.1
ENST00000439016.2
IKZF3




IKAROS family zinc finger 3 (Aiolos)




chr11_-_615942 0.062 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7



interferon regulatory factor 7



chr5_+_149865377 0.062 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr8_+_41348072 0.062 ENST00000405786.2
GOLGA7
golgin A7
chr1_+_207238326 0.062 ENST00000541914.1
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr17_+_46132037 0.061 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1


nuclear factor, erythroid 2-like 1


chr8_+_41348173 0.061 ENST00000357743.4
GOLGA7
golgin A7
chr6_-_43484718 0.061 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr1_-_24127256 0.061 ENST00000418277.1
GALE
UDP-galactose-4-epimerase
chr8_-_143833918 0.060 ENST00000359228.3
LYPD2
LY6/PLAUR domain containing 2
chr7_+_150758642 0.060 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr11_-_1036706 0.060 ENST00000421673.2
MUC6
mucin 6, oligomeric mucus/gel-forming
chr6_-_28367510 0.060 ENST00000361028.1
ZSCAN12
zinc finger and SCAN domain containing 12
chr4_-_10118348 0.059 ENST00000502702.1
WDR1
WD repeat domain 1
chr5_+_139027877 0.058 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr2_-_230786378 0.058 ENST00000430954.1
TRIP12
thyroid hormone receptor interactor 12
chr22_-_46931191 0.058 ENST00000454637.1
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1
chr19_+_56116771 0.057 ENST00000568956.1
ZNF865
zinc finger protein 865
chr19_+_16830815 0.056 ENST00000549814.1
NWD1
NACHT and WD repeat domain containing 1
chr1_-_21503337 0.056 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr19_+_49891533 0.055 ENST00000598730.1
ENST00000594905.1
ENST00000595828.1
ENST00000594043.1
CCDC155



coiled-coil domain containing 155



chr1_+_213224572 0.055 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1



ribosomal protein S6 kinase, 52kDa, polypeptide 1



chr2_+_102508955 0.054 ENST00000414004.2
FLJ20373
FLJ20373
chrX_+_1710484 0.054 ENST00000313871.3
ENST00000381261.3
AKAP17A

A kinase (PRKA) anchor protein 17A

chr2_-_197791441 0.053 ENST00000409475.1
ENST00000354764.4
ENST00000374738.3
PGAP1


post-GPI attachment to proteins 1


chr19_+_45409011 0.052 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE


apolipoprotein E


chr6_-_32908765 0.052 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr17_-_27224621 0.051 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
FLOT2


flotillin 2


chr5_-_140053152 0.051 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr5_-_131826457 0.051 ENST00000437654.1
ENST00000245414.4
IRF1

interferon regulatory factor 1

chr10_-_33623564 0.050 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chrX_+_53449805 0.050 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr12_+_56401268 0.049 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chrX_+_53449887 0.048 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr17_+_38278826 0.048 ENST00000577454.1
ENST00000578648.1
ENST00000579565.1
MSL1


male-specific lethal 1 homolog (Drosophila)


chr19_+_54369608 0.047 ENST00000336967.3
MYADM
myeloid-associated differentiation marker
chr2_+_108905325 0.047 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2


sulfotransferase family, cytosolic, 1C, member 2


chr5_-_180237445 0.047 ENST00000393340.3
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr3_-_18466026 0.046 ENST00000417717.2
SATB1
SATB homeobox 1
chr16_+_57279248 0.046 ENST00000562023.1
ENST00000563234.1
ARL2BP

ADP-ribosylation factor-like 2 binding protein

chr8_+_38243967 0.046 ENST00000524874.1
ENST00000379957.4
ENST00000523983.2
LETM2


leucine zipper-EF-hand containing transmembrane protein 2


chr16_+_3070356 0.046 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A


tumor necrosis factor receptor superfamily, member 12A


chr11_-_795400 0.045 ENST00000526152.1
ENST00000456706.2
ENST00000528936.1
SLC25A22


solute carrier family 25 (mitochondrial carrier: glutamate), member 22


chr2_-_109605663 0.045 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chr7_-_30739661 0.045 ENST00000445981.1
ENST00000348438.4
CRHR2

corticotropin releasing hormone receptor 2

chr11_+_63753883 0.044 ENST00000538426.1
ENST00000543004.1
OTUB1

OTU domain, ubiquitin aldehyde binding 1

chr8_+_38243821 0.044 ENST00000519476.2
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr1_+_11832179 0.044 ENST00000312793.5
C1orf167
chromosome 1 open reading frame 167

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 0.7 GO:0051795 positive regulation of catagen(GO:0051795)
0.2 0.5 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 1.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.4 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.2 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.0 0.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.2 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0042704 uterine wall breakdown(GO:0042704)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:2000646 lipid transport involved in lipid storage(GO:0010877) regulation of Cdc42 protein signal transduction(GO:0032489) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.0 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.0 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363) discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.2 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 1.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 1.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.7 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.2 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.8 GO:0016918 retinal binding(GO:0016918)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.0 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.0 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse