Motif ID: GLI3

Z-value: 0.986


Transcription factors associated with GLI3:

Gene SymbolEntrez IDGene Name
GLI3 ENSG00000106571.8 GLI3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GLI3hg19_v2_chr7_-_42276612_422767820.029.7e-01Click!


Activity profile for motif GLI3.

activity profile for motif GLI3


Sorted Z-values histogram for motif GLI3

Sorted Z-values for motif GLI3



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_45270077 1.205 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr2_-_136875712 0.947 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr12_-_45270151 0.922 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr5_-_149792295 0.874 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr21_+_36041688 0.860 ENST00000360731.3
ENST00000349499.2
CLIC6

chloride intracellular channel 6

chrX_+_148863584 0.855 ENST00000439010.2
ENST00000298974.5
ENST00000522429.1
ENST00000519822.1
MAGEA9



melanoma antigen family A, 9



chr3_-_38691119 0.792 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A




sodium channel, voltage-gated, type V, alpha subunit




chr11_+_68451943 0.736 ENST00000265643.3
GAL
galanin/GMAP prepropeptide
chrX_-_51812268 0.621 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B





melanoma antigen family D, 4B





chr19_-_43709817 0.575 ENST00000433626.2
ENST00000405312.3
PSG4

pregnancy specific beta-1-glycoprotein 4

chrX_+_37545012 0.572 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr22_-_46373004 0.570 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr9_-_113800341 0.565 ENST00000358883.4
LPAR1
lysophosphatidic acid receptor 1
chr4_-_74847800 0.540 ENST00000296029.3
PF4
platelet factor 4
chr9_-_113800705 0.531 ENST00000441240.1
LPAR1
lysophosphatidic acid receptor 1
chr2_-_241080069 0.531 ENST00000319460.1
OTOS
otospiralin
chr22_-_24622080 0.507 ENST00000425408.1
GGT5
gamma-glutamyltransferase 5
chr8_-_41655107 0.486 ENST00000347528.4
ENST00000289734.7
ENST00000379758.2
ENST00000396945.1
ENST00000396942.1
ENST00000352337.4
ANK1





ankyrin 1, erythrocytic





chr2_+_65215604 0.464 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr12_-_108714412 0.459 ENST00000412676.1
ENST00000550573.1
CMKLR1

chemokine-like receptor 1

chrX_-_148669116 0.449 ENST00000243314.5
MAGEA9B
melanoma antigen family A, 9B
chr6_-_26032288 0.440 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr6_+_125540951 0.436 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr8_+_98900132 0.436 ENST00000520016.1
MATN2
matrilin 2
chr18_+_21529811 0.430 ENST00000588004.1
LAMA3
laminin, alpha 3
chr1_-_182573514 0.430 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr9_-_139891165 0.425 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr2_+_137523086 0.422 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr17_+_76422409 0.420 ENST00000600087.1
AC061992.1
Uncharacterized protein
chr16_-_55867146 0.409 ENST00000422046.2
CES1
carboxylesterase 1
chr11_+_22214708 0.405 ENST00000324559.8
ANO5
anoctamin 5
chr4_+_72052964 0.401 ENST00000264485.5
ENST00000425175.1
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chrX_-_141293047 0.399 ENST00000247452.3
MAGEC2
melanoma antigen family C, 2
chr10_+_71389983 0.394 ENST00000373279.4
C10orf35
chromosome 10 open reading frame 35
chr8_+_120428546 0.392 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr15_-_26108355 0.391 ENST00000356865.6
ATP10A
ATPase, class V, type 10A
chr14_+_105941118 0.390 ENST00000550577.1
ENST00000538259.2
CRIP2

cysteine-rich protein 2

chr2_-_145275109 0.386 ENST00000431672.2
ZEB2
zinc finger E-box binding homeobox 2
chrX_+_51928002 0.379 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr1_+_31971828 0.373 ENST00000418618.1
RP11-439L8.3
RP11-439L8.3
chr21_-_28215332 0.372 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_-_45269430 0.368 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr3_-_171528227 0.368 ENST00000356327.5
ENST00000342215.6
ENST00000340989.4
ENST00000351298.4
PLD1



phospholipase D1, phosphatidylcholine-specific



chr3_+_44626446 0.365 ENST00000441021.1
ENST00000322734.2
ZNF660

zinc finger protein 660

chr6_-_133084580 0.365 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2


vanin 2


chr6_-_33037019 0.361 ENST00000437811.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr5_+_140566 0.353 ENST00000502646.1
PLEKHG4B
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr17_+_73750699 0.350 ENST00000584939.1
ITGB4
integrin, beta 4
chr3_+_186648307 0.345 ENST00000457772.2
ENST00000455441.1
ENST00000427315.1
ST6GAL1


ST6 beta-galactosamide alpha-2,6-sialyltranferase 1


chr19_+_12305824 0.339 ENST00000415793.1
ENST00000440004.1
ENST00000426044.1
CTD-2666L21.1


CTD-2666L21.1


chr8_-_17555164 0.336 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr9_-_113800317 0.334 ENST00000374431.3
LPAR1
lysophosphatidic acid receptor 1
chr18_+_59992514 0.332 ENST00000269485.7
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr12_+_52695617 0.331 ENST00000293525.5
KRT86
keratin 86
chr2_-_99485825 0.327 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr1_-_22215192 0.325 ENST00000374673.3
HSPG2
heparan sulfate proteoglycan 2
chr3_-_150421676 0.320 ENST00000474463.1
FAM194A
family with sequence similarity 194, member A
chr16_+_28996114 0.319 ENST00000395461.3
LAT
linker for activation of T cells
chr20_+_43343517 0.309 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr2_+_128403720 0.306 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr3_+_184081137 0.306 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chrX_-_48056199 0.306 ENST00000311798.1
ENST00000347757.1
SSX5

synovial sarcoma, X breakpoint 5

chr1_+_164528866 0.304 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chrX_+_51927919 0.303 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr18_+_59992527 0.302 ENST00000586569.1
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr1_+_47603109 0.300 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22


cytochrome P450, family 4, subfamily A, polypeptide 22


chr11_+_121461097 0.299 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr10_+_52750930 0.298 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chr12_-_62585203 0.295 ENST00000551449.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chrX_+_148864169 0.293 ENST00000523516.1
MAGEA9
melanoma antigen family A, 9
chr16_+_812506 0.292 ENST00000569566.1
MSLN
mesothelin
chr2_-_47382414 0.291 ENST00000294947.2
C2orf61
chromosome 2 open reading frame 61
chr6_-_169563013 0.290 ENST00000439703.1
RP11-417E7.1
RP11-417E7.1
chr1_+_179561011 0.286 ENST00000294848.8
ENST00000444136.1
TDRD5

tudor domain containing 5

chrX_-_48271344 0.285 ENST00000376884.2
ENST00000396928.1
SSX4B

synovial sarcoma, X breakpoint 4B

chr15_-_45422056 0.284 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
DUOXA1









dual oxidase maturation factor 1









chr3_+_184081213 0.275 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_18647326 0.269 ENST00000395667.1
ENST00000395665.4
ENST00000308799.4
ENST00000301938.4
FBXW10



F-box and WD repeat domain containing 10



chr8_-_27468842 0.268 ENST00000523500.1
CLU
clusterin
chr12_-_96184913 0.268 ENST00000538383.1
NTN4
netrin 4
chr19_+_2096868 0.267 ENST00000395296.1
ENST00000395301.3
IZUMO4

IZUMO family member 4

chr8_+_22250334 0.267 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr8_-_27462822 0.266 ENST00000522098.1
CLU
clusterin
chr8_+_31497271 0.266 ENST00000520407.1
NRG1
neuregulin 1
chr17_-_19651668 0.264 ENST00000494157.2
ENST00000225740.6
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr20_+_43343886 0.261 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr15_-_72490114 0.260 ENST00000309731.7
GRAMD2
GRAM domain containing 2
chr2_-_233877912 0.255 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr20_+_43343476 0.254 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr9_-_117160738 0.254 ENST00000448674.1
RP11-9M16.2
RP11-9M16.2
chr10_+_52751010 0.253 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr19_+_16771936 0.250 ENST00000187762.2
ENST00000599479.1
TMEM38A

transmembrane protein 38A

chr3_+_45067659 0.250 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr3_+_184081175 0.249 ENST00000452961.1
ENST00000296223.3
POLR2H

polymerase (RNA) II (DNA directed) polypeptide H

chr12_-_5849134 0.249 ENST00000545860.1
ANO2
anoctamin 2
chr12_-_45269769 0.248 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr4_+_72053017 0.248 ENST00000351898.6
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr5_-_146833222 0.246 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr7_-_4923315 0.244 ENST00000399583.3
RADIL
Ras association and DIL domains
chr18_+_52385068 0.242 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr16_+_28996572 0.241 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT


linker for activation of T cells


chr7_+_1126437 0.239 ENST00000413368.1
ENST00000397092.1
GPER1

G protein-coupled estrogen receptor 1

chr19_-_35323762 0.238 ENST00000590963.1
CTC-523E23.4
CTC-523E23.4
chr8_-_144660771 0.237 ENST00000449291.2
NAPRT1
nicotinate phosphoribosyltransferase domain containing 1
chr20_+_62185491 0.237 ENST00000370097.1
C20orf195
chromosome 20 open reading frame 195
chr1_-_22222764 0.235 ENST00000439717.2
ENST00000412328.1
HSPG2

heparan sulfate proteoglycan 2

chr12_+_7055631 0.235 ENST00000543115.1
ENST00000399448.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr3_-_182817297 0.235 ENST00000539926.1
ENST00000476176.1
MCCC1

methylcrotonoyl-CoA carboxylase 1 (alpha)

chr14_-_60097524 0.235 ENST00000342503.4
RTN1
reticulon 1
chr11_-_116708302 0.234 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1



apolipoprotein A-I



chr2_-_224702270 0.230 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3



adaptor-related protein complex 1, sigma 3 subunit



chr8_-_27468945 0.230 ENST00000405140.3
CLU
clusterin
chr3_-_169899504 0.230 ENST00000474275.1
ENST00000484931.1
ENST00000494943.1
ENST00000497658.1
ENST00000465896.1
ENST00000475729.1
ENST00000495893.2
ENST00000481639.1
ENST00000467570.1
ENST00000466189.1
PHC3









polyhomeotic homolog 3 (Drosophila)









chr20_-_23731893 0.229 ENST00000398402.1
CST1
cystatin SN
chr16_+_75256507 0.227 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr14_+_105147464 0.226 ENST00000540171.2
RP11-982M15.6
RP11-982M15.6
chr17_-_39928106 0.224 ENST00000540235.1
JUP
junction plakoglobin
chr8_+_124194875 0.223 ENST00000522648.1
ENST00000276699.6
FAM83A

family with sequence similarity 83, member A

chr1_-_177133998 0.219 ENST00000367657.3
ASTN1
astrotactin 1
chr3_-_182817367 0.216 ENST00000265594.4
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr10_-_116164239 0.215 ENST00000419268.1
ENST00000304129.4
ENST00000545353.1
AFAP1L2


actin filament associated protein 1-like 2


chr8_-_27468717 0.215 ENST00000520796.1
ENST00000520491.1
CLU

clusterin

chr5_+_68788594 0.215 ENST00000396442.2
ENST00000380766.2
OCLN

occludin

chr9_-_139637355 0.213 ENST00000474369.1
ENST00000497771.1
ENST00000527229.1
LCN10


lipocalin 10


chr1_-_31902614 0.212 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr8_-_33457453 0.211 ENST00000523956.1
ENST00000256261.4
DUSP26

dual specificity phosphatase 26 (putative)

chr2_+_10560147 0.211 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr8_-_82024290 0.211 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr12_+_113354341 0.208 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_111649074 0.207 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr8_+_21881636 0.207 ENST00000520125.1
ENST00000521157.1
ENST00000397940.1
ENST00000522813.1
NPM2



nucleophosmin/nucleoplasmin 2



chr8_+_124194752 0.207 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr10_-_46970474 0.205 ENST00000503753.1
ENST00000374321.4
SYT15

synaptotagmin XV

chr8_-_42065187 0.205 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT


plasminogen activator, tissue


chr2_-_204400013 0.204 ENST00000374489.2
ENST00000374488.2
ENST00000308091.4
ENST00000453034.1
ENST00000420371.1
RAPH1




Ras association (RalGDS/AF-6) and pleckstrin homology domains 1




chr6_-_46620522 0.204 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr1_+_36396313 0.204 ENST00000324350.5
AGO3
argonaute RISC catalytic component 3
chr12_+_7055767 0.203 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_76044934 0.201 ENST00000238667.4
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chrX_+_49160148 0.201 ENST00000407599.3
GAGE10
G antigen 10
chr8_+_21882244 0.200 ENST00000289820.6
ENST00000381530.5
NPM2

nucleophosmin/nucleoplasmin 2

chr6_-_26027480 0.199 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr2_-_224702740 0.198 ENST00000444408.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr21_-_35831880 0.197 ENST00000399289.3
ENST00000432085.1
KCNE1

potassium voltage-gated channel, Isk-related family, member 1

chr7_-_156433195 0.195 ENST00000333319.6
C7orf13
chromosome 7 open reading frame 13
chr1_+_201979645 0.195 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr19_+_12305895 0.195 ENST00000451691.2
CTD-2666L21.1
CTD-2666L21.1
chr8_-_17533838 0.195 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr7_+_1126461 0.195 ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr1_-_21606013 0.195 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr12_+_57522692 0.195 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr10_+_11060004 0.193 ENST00000542579.1
ENST00000399850.3
ENST00000417956.2
CELF2


CUGBP, Elav-like family member 2


chr5_+_179247759 0.192 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1



sequestosome 1



chr3_+_187930429 0.191 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_197458323 0.189 ENST00000452031.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr12_-_13248562 0.189 ENST00000457134.2
ENST00000537302.1
GSG1

germ cell associated 1

chr17_-_34808047 0.188 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1D3G




TBC1D3H
TBC1 domain family, member 3G




TBC1 domain family, member 3H
chr22_+_25595817 0.188 ENST00000215855.2
ENST00000404334.1
CRYBB3

crystallin, beta B3

chr18_+_70536215 0.187 ENST00000578967.1
RP11-676J15.1
RP11-676J15.1
chr19_+_1908013 0.185 ENST00000454697.1
ADAT3
adenosine deaminase, tRNA-specific 3
chr11_+_114168085 0.185 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr1_+_15480197 0.185 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51


transmembrane protein 51


chr7_-_4923259 0.184 ENST00000536091.1
RADIL
Ras association and DIL domains
chr1_-_31661000 0.183 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1


Na+/K+ transporting ATPase interacting 1


chr5_-_43412418 0.183 ENST00000537013.1
ENST00000361115.4
CCL28

chemokine (C-C motif) ligand 28

chr11_-_111383064 0.183 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
BTG4


B-cell translocation gene 4


chr2_-_204399976 0.181 ENST00000457812.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr12_+_50355647 0.181 ENST00000293599.6
AQP5
aquaporin 5
chr16_+_57844549 0.179 ENST00000564282.1
CTD-2600O9.1
uncharacterized protein LOC388282
chrX_-_48693955 0.179 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_-_224702257 0.178 ENST00000409375.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr1_+_43613566 0.178 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr7_-_95064264 0.178 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2


paraoxonase 2


chr14_+_96087251 0.177 ENST00000555032.1
RP11-1070N10.5
RP11-1070N10.5
chr17_-_80059726 0.175 ENST00000583053.1
CCDC57
coiled-coil domain containing 57
chr5_+_149340282 0.174 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr9_-_27529726 0.173 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr11_-_64510409 0.173 ENST00000394429.1
ENST00000394428.1
RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

chr5_+_149340339 0.171 ENST00000433184.1
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr4_-_40632757 0.171 ENST00000511902.1
ENST00000505220.1
RBM47

RNA binding motif protein 47

chr10_-_116164450 0.170 ENST00000369271.3
AFAP1L2
actin filament associated protein 1-like 2
chr3_+_187930491 0.169 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_+_48242863 0.168 ENST00000376886.2
ENST00000375517.3
SSX4

synovial sarcoma, X breakpoint 4

chr7_+_104581389 0.167 ENST00000415513.1
ENST00000417026.1
RP11-325F22.2

RP11-325F22.2

chr1_-_153538292 0.167 ENST00000497140.1
ENST00000368708.3
S100A2

S100 calcium binding protein A2

chr11_-_1785139 0.167 ENST00000236671.2
CTSD
cathepsin D
chr3_+_186648507 0.167 ENST00000458216.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr16_+_28996364 0.166 ENST00000564277.1
LAT
linker for activation of T cells
chr1_+_15479054 0.166 ENST00000376014.3
ENST00000451326.2
TMEM51

transmembrane protein 51

chr14_+_104394770 0.165 ENST00000409874.4
ENST00000339063.5
TDRD9

tudor domain containing 9

chr1_+_6845384 0.165 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr3_-_176914963 0.165 ENST00000450267.1
ENST00000431674.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr19_-_35992780 0.163 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN


dermokine


chr9_+_132044730 0.163 ENST00000455981.1
RP11-344B5.2
RP11-344B5.2
chr19_-_44285401 0.163 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_-_224702201 0.163 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr1_-_11865982 0.163 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr11_+_76493294 0.162 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr3_-_169482840 0.162 ENST00000602385.1
TERC
telomerase RNA component
chr3_-_176914998 0.162 ENST00000431421.1
ENST00000422066.1
ENST00000413084.1
TBL1XR1


transducin (beta)-like 1 X-linked receptor 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.7 GO:0051795 positive regulation of catagen(GO:0051795)
0.2 0.6 GO:0071812 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.2 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 0.9 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 2.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.4 GO:2000724 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.5 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 1.0 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.9 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.1 0.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.5 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1 0.9 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.3 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.1 0.1 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.1 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.4 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.2 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.5 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1 0.1 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.4 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.2 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.7 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.0 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0040010 positive regulation of growth rate(GO:0040010) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.6 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0042335 cuticle development(GO:0042335)
0.0 0.3 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.1 GO:0050787 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.0 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.1 GO:0072011 glomerular endothelium development(GO:0072011)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.1 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.1 GO:0072008 glomerular mesangial cell differentiation(GO:0072008)
0.0 0.1 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0002584 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.4 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.1 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.3 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0060018 positive regulation of chromatin assembly or disassembly(GO:0045799) astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0044010 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455) positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.3 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.3 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.2 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 1.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.0 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.0 GO:0060922 atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.0 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.0 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.0 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.0 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.0 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.8 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.0 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.0 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.0 GO:0035617 stress granule disassembly(GO:0035617)
0.0 1.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.0 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 0.4 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 1.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.5 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0044753 amphisome(GO:0044753)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0042585 female germ cell nucleus(GO:0001674) germinal vesicle(GO:0042585)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 1.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.4 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.2 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.5 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 2.0 GO:0070325 lipoprotein particle receptor binding(GO:0070325)
0.0 0.3 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.5 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.0 GO:0045142 triplex DNA binding(GO:0045142)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.0 GO:0015235 cobalamin transporter activity(GO:0015235)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 0.1 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 3.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.1 0.2 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.9 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 0.9 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.2 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins