Motif ID: GLI2

Z-value: 0.623


Transcription factors associated with GLI2:

Gene SymbolEntrez IDGene Name
GLI2 ENSG00000074047.16 GLI2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GLI2hg19_v2_chr2_+_121493717_121493823-0.176.7e-01Click!


Activity profile for motif GLI2.

activity profile for motif GLI2


Sorted Z-values histogram for motif GLI2

Sorted Z-values for motif GLI2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_46756351 1.085 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_6481776 0.901 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C


DENN/MADD domain containing 1C


chr14_-_75083313 0.835 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2

CTD-2207P18.2

chr14_-_51561784 0.789 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr19_-_6481759 0.674 ENST00000588421.1
DENND1C
DENN/MADD domain containing 1C
chr16_+_29150963 0.535 ENST00000563477.1
RP11-426C22.5
RP11-426C22.5
chr6_+_43968306 0.521 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr19_-_10628117 0.492 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr22_-_32651326 0.419 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr8_+_7705398 0.412 ENST00000400125.2
ENST00000434307.2
ENST00000326558.5
ENST00000351436.4
ENST00000528033.1
SPAG11A




sperm associated antigen 11A




chr1_+_203096831 0.398 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr1_+_203097407 0.392 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr17_+_39261584 0.382 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr14_+_100531615 0.378 ENST00000392920.3
EVL
Enah/Vasp-like
chr9_+_135285579 0.377 ENST00000343036.2
ENST00000393216.2
C9orf171

chromosome 9 open reading frame 171

chr19_+_44084696 0.375 ENST00000562255.1
ENST00000569031.2
PINLYP

phospholipase A2 inhibitor and LY6/PLAUR domain containing

chr5_+_176237478 0.373 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr12_-_43945724 0.371 ENST00000389420.3
ENST00000553158.1
ADAMTS20

ADAM metallopeptidase with thrombospondin type 1 motif, 20

chr8_-_7320974 0.371 ENST00000528943.1
ENST00000359758.5
ENST00000361111.2
ENST00000398462.2
ENST00000297498.2
ENST00000317900.5
SPAG11B





sperm associated antigen 11B





chr20_+_44637526 0.361 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr20_-_23969416 0.351 ENST00000335694.4
GGTLC1
gamma-glutamyltransferase light chain 1
chr14_+_100531738 0.344 ENST00000555706.1
EVL
Enah/Vasp-like
chr19_-_54567159 0.340 ENST00000338372.2
ENST00000376626.1
VSTM1

V-set and transmembrane domain containing 1

chr10_-_46313036 0.337 ENST00000411791.3
FAM25E
family with sequence similarity 25, member E
chr16_+_89686991 0.332 ENST00000393092.3
DPEP1
dipeptidase 1 (renal)
chr15_-_39486510 0.331 ENST00000560743.1
RP11-265N7.1
RP11-265N7.1
chr4_-_6383594 0.327 ENST00000335585.5
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr14_-_94856951 0.320 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
SERPINA1



serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1



chr1_+_243419306 0.317 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8



serologically defined colon cancer antigen 8



chr2_+_220492287 0.317 ENST00000273063.6
ENST00000373762.3
SLC4A3

solute carrier family 4 (anion exchanger), member 3

chr14_-_94857004 0.316 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
SERPINA1




serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1




chr19_-_33793430 0.308 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr14_-_94856987 0.300 ENST00000449399.3
ENST00000404814.4
SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

chr14_+_79745682 0.295 ENST00000557594.1
NRXN3
neurexin 3
chr4_-_186732048 0.294 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr12_-_82152420 0.287 ENST00000552948.1
ENST00000548586.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr12_-_82153087 0.280 ENST00000547623.1
ENST00000549396.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr19_-_10628098 0.279 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr5_-_9546180 0.275 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr12_+_116985896 0.272 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chr12_-_82152444 0.269 ENST00000549325.1
ENST00000550584.2
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr20_+_44746885 0.263 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr20_+_44746939 0.263 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr12_-_132690337 0.262 ENST00000541995.1
ENST00000542942.1
GALNT9

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)

chr14_+_79746249 0.258 ENST00000428277.2
NRXN3
neurexin 3
chr14_+_78870030 0.255 ENST00000553631.1
ENST00000554719.1
NRXN3

neurexin 3

chr10_+_88414338 0.247 ENST00000241891.5
ENST00000443292.1
OPN4

opsin 4

chr5_+_9546306 0.247 ENST00000508179.1
SNHG18
small nucleolar RNA host gene 18 (non-protein coding)
chr2_+_95537170 0.240 ENST00000295201.4
TEKT4
tektin 4
chr3_+_54157480 0.239 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr9_+_135285430 0.237 ENST00000393215.3
C9orf171
chromosome 9 open reading frame 171
chr10_-_5638048 0.236 ENST00000478294.1
RP13-463N16.6
RP13-463N16.6
chr7_+_130131907 0.235 ENST00000223215.4
ENST00000437945.1
MEST

mesoderm specific transcript

chr16_+_56385290 0.235 ENST00000564727.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr1_-_63782888 0.233 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr13_-_30169807 0.233 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_+_95537248 0.233 ENST00000427593.2
TEKT4
tektin 4
chr19_-_55668093 0.232 ENST00000588882.1
ENST00000586858.1
TNNI3

troponin I type 3 (cardiac)

chr22_+_45064593 0.230 ENST00000432186.1
PRR5
proline rich 5 (renal)
chr14_-_94854926 0.228 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1


chr12_+_6881678 0.228 ENST00000441671.2
ENST00000203629.2
LAG3

lymphocyte-activation gene 3

chr9_+_126118449 0.227 ENST00000359999.3
ENST00000373631.3
CRB2

crumbs homolog 2 (Drosophila)

chr16_+_30194118 0.226 ENST00000563778.1
CORO1A
coronin, actin binding protein, 1A
chr14_+_96087251 0.226 ENST00000555032.1
RP11-1070N10.5
RP11-1070N10.5
chr16_-_30064244 0.220 ENST00000571269.1
ENST00000561666.1
FAM57B

family with sequence similarity 57, member B

chr17_-_48207115 0.218 ENST00000511964.1
SAMD14
sterile alpha motif domain containing 14
chr2_+_220492116 0.218 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr11_+_60739115 0.216 ENST00000344028.5
ENST00000346437.4
CD6

CD6 molecule

chr5_-_850676 0.215 ENST00000424784.2
ZDHHC11
zinc finger, DHHC-type containing 11
chr7_+_149412094 0.215 ENST00000255992.10
ENST00000319551.8
KRBA1

KRAB-A domain containing 1

chr2_+_220492373 0.214 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr3_+_54156664 0.213 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr3_-_48659193 0.212 ENST00000330862.3
TMEM89
transmembrane protein 89
chr14_+_96342729 0.210 ENST00000504119.1
LINC00617
long intergenic non-protein coding RNA 617
chr11_+_60739249 0.210 ENST00000542157.1
ENST00000433107.2
ENST00000452451.2
ENST00000352009.5
CD6



CD6 molecule



chr6_+_72596604 0.208 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1






regulating synaptic membrane exocytosis 1






chr1_-_32264250 0.208 ENST00000528579.1
SPOCD1
SPOC domain containing 1
chr1_+_154378049 0.206 ENST00000512471.1
IL6R
interleukin 6 receptor
chr2_-_70475730 0.205 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1


TIA1 cytotoxic granule-associated RNA binding protein


chr2_-_70475586 0.205 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr2_-_70475701 0.203 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr10_-_14880002 0.202 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr7_-_112726393 0.202 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85



G protein-coupled receptor 85



chr10_+_88414298 0.201 ENST00000372071.2
OPN4
opsin 4
chr19_+_44085189 0.200 ENST00000562365.2
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr21_-_32716556 0.199 ENST00000455508.1
TIAM1
T-cell lymphoma invasion and metastasis 1
chr3_+_124355944 0.197 ENST00000459915.1
KALRN
kalirin, RhoGEF kinase
chr20_+_61867235 0.197 ENST00000342412.6
ENST00000217169.3
BIRC7

baculoviral IAP repeat containing 7

chr12_+_121088291 0.195 ENST00000351200.2
CABP1
calcium binding protein 1
chr9_+_126131131 0.195 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr2_+_126468524 0.193 ENST00000430692.1
AC097499.1
AC097499.1
chr17_+_7323634 0.192 ENST00000323675.3
SPEM1
spermatid maturation 1
chr21_-_46330545 0.192 ENST00000320216.6
ENST00000397852.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr11_+_1463728 0.191 ENST00000544817.1
BRSK2
BR serine/threonine kinase 2
chr11_+_60739140 0.188 ENST00000313421.7
CD6
CD6 molecule
chr8_-_133493200 0.186 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr1_-_161207875 0.184 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
















nuclear receptor subfamily 1, group I, member 3
















chr19_+_41860047 0.183 ENST00000604123.1
TMEM91
transmembrane protein 91
chr1_+_155051379 0.181 ENST00000418360.2
EFNA3
ephrin-A3
chr19_+_45165545 0.178 ENST00000592472.1
ENST00000587729.1
ENST00000585657.1
ENST00000592789.1
ENST00000591979.1
CEACAM19




carcinoembryonic antigen-related cell adhesion molecule 19




chr22_+_44427230 0.177 ENST00000444029.1
PARVB
parvin, beta
chr19_+_45418067 0.176 ENST00000589078.1
ENST00000586638.1
APOC1

apolipoprotein C-I

chr2_+_120187465 0.173 ENST00000409826.1
ENST00000417645.1
TMEM37

transmembrane protein 37

chr3_+_113616317 0.172 ENST00000440446.2
ENST00000488680.1
GRAMD1C

GRAM domain containing 1C

chr2_+_74710194 0.170 ENST00000410003.1
ENST00000442235.2
ENST00000233623.5
TTC31


tetratricopeptide repeat domain 31


chr6_+_33172407 0.170 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr19_+_18530146 0.170 ENST00000348495.6
ENST00000270061.7
SSBP4

single stranded DNA binding protein 4

chr2_+_85132749 0.168 ENST00000233143.4
TMSB10
thymosin beta 10
chr12_-_132690573 0.166 ENST00000397325.2
ENST00000538356.1
GALNT9

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)

chr15_+_29211570 0.163 ENST00000558804.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr22_-_20004330 0.161 ENST00000263207.3
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr19_+_45417921 0.160 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1


apolipoprotein C-I


chr1_-_241520525 0.160 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr19_-_44084586 0.159 ENST00000599693.1
ENST00000598165.1
XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1

chr5_-_176889381 0.158 ENST00000393563.4
ENST00000512501.1
DBN1

drebrin 1

chr11_-_1033062 0.156 ENST00000525923.1
MUC6
mucin 6, oligomeric mucus/gel-forming
chr4_-_186732241 0.155 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr1_+_35220613 0.154 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr3_+_16926441 0.154 ENST00000418129.2
ENST00000396755.2
PLCL2

phospholipase C-like 2

chr12_-_57882577 0.153 ENST00000393797.2
ARHGAP9
Rho GTPase activating protein 9
chr1_+_41707996 0.152 ENST00000425554.1
RP11-399E6.1
RP11-399E6.1
chr13_+_27825706 0.152 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21


ribosomal protein L21


chr13_+_77526602 0.151 ENST00000449753.1
IRG1
immunoresponsive 1 homolog (mouse)
chr6_+_90272488 0.151 ENST00000485637.1
ENST00000522705.1
ANKRD6

ankyrin repeat domain 6

chrX_+_70503526 0.150 ENST00000413858.1
ENST00000450092.1
NONO

non-POU domain containing, octamer-binding

chr4_+_62067860 0.150 ENST00000514591.1
LPHN3
latrophilin 3
chr21_-_45079341 0.150 ENST00000443485.1
ENST00000291560.2
HSF2BP

heat shock transcription factor 2 binding protein

chr16_-_1538765 0.149 ENST00000447419.2
ENST00000440447.2
PTX4

pentraxin 4, long

chr17_+_42923686 0.149 ENST00000591513.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr11_-_64527425 0.148 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr11_-_71159380 0.148 ENST00000525346.1
ENST00000531364.1
ENST00000529990.1
ENST00000527316.1
ENST00000407721.2
DHCR7




7-dehydrocholesterol reductase




chr12_+_57853918 0.147 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1



GLI family zinc finger 1



chr8_+_21916710 0.146 ENST00000523266.1
ENST00000519907.1
DMTN

dematin actin binding protein

chr3_-_50336548 0.146 ENST00000513170.1
ENST00000450982.1
ENST00000450489.1
HYAL3

NAT6
hyaluronoglucosaminidase 3

N-acetyltransferase 6 (GCN5-related)
chr16_+_58497587 0.145 ENST00000569404.1
ENST00000569539.1
ENST00000564126.1
ENST00000565304.1
ENST00000567667.1
NDRG4




NDRG family member 4




chr20_-_896960 0.144 ENST00000381922.3
ENST00000546022.1
ANGPT4

angiopoietin 4

chr3_+_54156570 0.144 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr19_-_48673465 0.144 ENST00000598938.1
LIG1
ligase I, DNA, ATP-dependent
chr6_+_72596406 0.144 ENST00000491071.2
RIMS1
regulating synaptic membrane exocytosis 1
chr17_+_56270084 0.144 ENST00000225371.5
EPX
eosinophil peroxidase
chr3_+_156008809 0.143 ENST00000302490.8
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr19_-_54567035 0.142 ENST00000366170.2
ENST00000425006.2
VSTM1

V-set and transmembrane domain containing 1

chr3_+_111260856 0.142 ENST00000352690.4
CD96
CD96 molecule
chr21_+_45079409 0.140 ENST00000340648.4
RRP1B
ribosomal RNA processing 1B
chr22_+_39410287 0.139 ENST00000381568.4
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr9_+_117085336 0.139 ENST00000259396.8
ENST00000538816.1
ORM1

orosomucoid 1

chr17_-_17723746 0.137 ENST00000577897.1
SREBF1
sterol regulatory element binding transcription factor 1
chr21_-_35340759 0.136 ENST00000607953.1
AP000569.9
AP000569.9
chr15_+_81591757 0.135 ENST00000558332.1
IL16
interleukin 16
chr10_-_113943447 0.134 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM


glycerol-3-phosphate acyltransferase, mitochondrial


chr8_+_21916680 0.134 ENST00000358242.3
ENST00000415253.1
DMTN

dematin actin binding protein

chr1_-_157108266 0.134 ENST00000326786.4
ETV3
ets variant 3
chr19_+_45417812 0.133 ENST00000592535.1
APOC1
apolipoprotein C-I
chr3_-_192635943 0.131 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr14_+_94577074 0.131 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27








interferon, alpha-inducible protein 27








chr3_-_46759314 0.130 ENST00000315170.7
PRSS50
protease, serine, 50
chr22_-_50708781 0.130 ENST00000449719.2
ENST00000330651.6
MAPK11

mitogen-activated protein kinase 11

chr1_-_241520385 0.129 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr13_-_60737898 0.129 ENST00000377908.2
ENST00000400319.1
ENST00000400320.1
ENST00000267215.4
DIAPH3



diaphanous-related formin 3



chr19_-_2702681 0.128 ENST00000382159.3
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr17_+_50939459 0.128 ENST00000412360.1
AC102948.2
Uncharacterized protein
chr13_+_100258907 0.128 ENST00000376355.3
ENST00000376360.1
ENST00000444838.2
ENST00000376354.1
ENST00000339105.4
CLYBL




citrate lyase beta like




chr16_+_31885079 0.127 ENST00000300870.10
ENST00000394846.3
ZNF267

zinc finger protein 267

chr5_-_150284532 0.127 ENST00000394226.2
ENST00000446148.2
ENST00000274599.5
ENST00000418587.2
ZNF300



zinc finger protein 300



chr22_+_24115000 0.127 ENST00000215743.3
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr10_+_104474353 0.127 ENST00000602647.1
ENST00000602439.1
ENST00000602764.1
SFXN2


sideroflexin 2


chr11_-_12030629 0.126 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr15_-_75918109 0.126 ENST00000567134.1
ENST00000308588.5
SNUPN

snurportin 1

chr16_-_30022293 0.126 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A


double C2-like domains, alpha


chr14_+_95048217 0.124 ENST00000557598.1
ENST00000556064.1
SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

chr1_-_95285652 0.124 ENST00000442418.1
LINC01057
long intergenic non-protein coding RNA 1057
chr19_+_45417504 0.124 ENST00000588750.1
ENST00000588802.1
APOC1

apolipoprotein C-I

chr14_+_21467414 0.124 ENST00000554422.1
ENST00000298681.4
SLC39A2

solute carrier family 39 (zinc transporter), member 2

chr17_+_55333876 0.123 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr19_+_55795493 0.123 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr9_-_135754164 0.123 ENST00000298545.3
AK8
adenylate kinase 8
chr19_+_18530184 0.123 ENST00000601357.2
SSBP4
single stranded DNA binding protein 4
chr13_-_60738003 0.123 ENST00000400330.1
ENST00000400324.4
DIAPH3

diaphanous-related formin 3

chr1_+_6105974 0.122 ENST00000378083.3
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr5_+_76506706 0.122 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B




phosphodiesterase 8B




chr19_-_48673552 0.122 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chr22_-_31688431 0.122 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr15_+_81589254 0.120 ENST00000394652.2
IL16
interleukin 16
chr19_-_12941215 0.120 ENST00000458671.2
RTBDN
retbindin
chr12_-_122712038 0.120 ENST00000413918.1
ENST00000443649.3
DIABLO

diablo, IAP-binding mitochondrial protein

chr15_-_75918023 0.119 ENST00000564644.1
ENST00000371091.5
ENST00000564675.1
SNUPN


snurportin 1


chr3_+_49591881 0.118 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr17_-_7018128 0.118 ENST00000380952.2
ENST00000254850.7
ASGR2

asialoglycoprotein receptor 2

chr11_+_123301012 0.118 ENST00000533341.1
AP000783.1
Uncharacterized protein
chr9_-_16215897 0.117 ENST00000433347.1
C9orf92
chromosome 9 open reading frame 92
chr1_-_40105617 0.117 ENST00000372852.3
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr6_+_90272339 0.116 ENST00000522779.1
ANKRD6
ankyrin repeat domain 6
chr16_+_67063036 0.116 ENST00000290858.6
ENST00000564034.1
CBFB

core-binding factor, beta subunit

chr22_+_39760130 0.116 ENST00000381535.4
SYNGR1
synaptogyrin 1
chr10_-_99258135 0.116 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19




MMS19 nucleotide excision repair homolog (S. cerevisiae)




chr1_-_85358850 0.115 ENST00000370611.3
LPAR3
lysophosphatidic acid receptor 3
chr17_-_73761222 0.115 ENST00000437911.1
ENST00000225614.2
GALK1

galactokinase 1

chr19_+_18529674 0.115 ENST00000597724.2
SSBP4
single stranded DNA binding protein 4
chr16_+_67063142 0.114 ENST00000412916.2
CBFB
core-binding factor, beta subunit
chr10_+_104474207 0.114 ENST00000602831.1
ENST00000369893.5
SFXN2

sideroflexin 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.2 0.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.6 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.3 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.5 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 0.3 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1 0.4 GO:0014028 notochord formation(GO:0014028)
0.1 0.5 GO:0033590 response to cobalamin(GO:0033590)
0.1 0.2 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.3 GO:0032796 uropod organization(GO:0032796)
0.1 0.2 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.8 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.0 0.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0006173 dADP biosynthetic process(GO:0006173)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.3 GO:0045945 urea cycle(GO:0000050) positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.2 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.4 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.0 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.2 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:2000823 regulation of androgen receptor activity(GO:2000823) positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of locomotion involved in locomotory behavior(GO:0090325) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.0 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.0 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.5 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.2 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.0 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.7 GO:0006953 acute-phase response(GO:0006953)
0.0 0.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.0 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 1.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.0 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.0 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.2 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.2 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.9 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.5 GO:0003909 DNA ligase activity(GO:0003909)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.0 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.0 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.0 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.0 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.0 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_OPSINS Genes involved in Opsins
0.0 0.8 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.6 REACTOME_BASE_EXCISION_REPAIR Genes involved in Base Excision Repair
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor