• All motifs sorted by activity significance
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• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: GATA6

Z-value: 0.376

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_46716969	0.591	ENST00000435666.2	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_153599269	0.532	ENST00000463297.1	RP11-217E22.5	RP11-217E22.5
chr1_+_206317450	0.266	ENST00000358184.2 ENST00000361052.3 ENST00000360218.2	CTSE	cathepsin E
chr18_+_43304137	0.259	ENST00000502059.2 ENST00000586951.1 ENST00000589322.2 ENST00000415427.3 ENST00000535474.1 ENST00000402943.2	SLC14A1	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr4_-_186696636	0.243	ENST00000444771.1	SORBS2	sorbin and SH3 domain containing 2
chr4_-_186697044	0.231	ENST00000437304.2	SORBS2	sorbin and SH3 domain containing 2
chr1_+_206317591	0.225	ENST00000432969.2	CTSE	cathepsin E
chr6_-_46048116	0.205	ENST00000185206.6	CLIC5	chloride intracellular channel 5
chr4_-_186696561	0.200	ENST00000445115.1 ENST00000451701.1 ENST00000457247.1 ENST00000435480.1 ENST00000425679.1 ENST00000457934.1	SORBS2	sorbin and SH3 domain containing 2
chr18_+_43304092	0.181	ENST00000321925.4 ENST00000587601.1	SLC14A1	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr17_+_74381343	0.172	ENST00000392496.3	SPHK1	sphingosine kinase 1
chr2_+_3642545	0.145	ENST00000382062.2 ENST00000236693.7 ENST00000349077.4	COLEC11	collectin sub-family member 11
chr3_+_148583043	0.142	ENST00000296046.3	CPA3	carboxypeptidase A3 (mast cell)
chr14_+_100204027	0.141	ENST00000554479.1 ENST00000555145.1	EML1	echinoderm microtubule associated protein like 1
chr16_+_71560154	0.136	ENST00000539698.3	CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr16_+_71560023	0.133	ENST00000572450.1	CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr2_+_102928009	0.129	ENST00000404917.2 ENST00000447231.1	IL1RL1	interleukin 1 receptor-like 1
chr7_+_155090271	0.127	ENST00000476756.1	INSIG1	insulin induced gene 1
chr14_+_75988768	0.118	ENST00000286639.6	BATF	basic leucine zipper transcription factor, ATF-like
chr6_+_12290586	0.116	ENST00000379375.5	EDN1	endothelin 1
chr1_+_25599018	0.115	ENST00000417538.2 ENST00000357542.4 ENST00000568195.1 ENST00000342055.5 ENST00000423810.2	RHD	Rh blood group, D antigen
chr17_+_38673270	0.115	ENST00000578280.1	RP5-1028K7.2	RP5-1028K7.2
chr2_+_102927962	0.115	ENST00000233954.1 ENST00000393393.3 ENST00000410040.1	IL1RL1 IL18R1	interleukin 1 receptor-like 1 interleukin 18 receptor 1
chr8_-_116681686	0.109	ENST00000519815.1	TRPS1	trichorhinophalangeal syndrome I
chr19_-_13213662	0.105	ENST00000264824.4	LYL1	lymphoblastic leukemia derived sequence 1
chr19_-_13213954	0.100	ENST00000590974.1	LYL1	lymphoblastic leukemia derived sequence 1
chr17_+_19314432	0.098	ENST00000575165.2	RNF112	ring finger protein 112
chr14_+_75988851	0.082	ENST00000555504.1	BATF	basic leucine zipper transcription factor, ATF-like
chr1_-_27240455	0.082	ENST00000254227.3	NR0B2	nuclear receptor subfamily 0, group B, member 2
chr12_-_120765565	0.081	ENST00000423423.3 ENST00000308366.4	PLA2G1B	phospholipase A2, group IB (pancreas)
chr2_+_220495800	0.081	ENST00000413743.1	SLC4A3	solute carrier family 4 (anion exchanger), member 3
chr6_-_86099898	0.078	ENST00000455071.1	RP11-30P6.6	RP11-30P6.6
chr16_+_616995	0.078	ENST00000293874.2 ENST00000409527.2 ENST00000424439.2 ENST00000540585.1	PIGQ NHLRC4	phosphatidylinositol glycan anchor biosynthesis, class Q NHL repeat containing 4
chr1_-_42630389	0.075	ENST00000357001.2	GUCA2A	guanylate cyclase activator 2A (guanylin)
chr17_+_56833184	0.071	ENST00000308249.2	PPM1E	protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr3_+_137717571	0.069	ENST00000343735.4	CLDN18	claudin 18
chr10_-_127505167	0.069	ENST00000368786.1	UROS	uroporphyrinogen III synthase
chr11_-_26743546	0.067	ENST00000280467.6 ENST00000396005.3	SLC5A12	solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr1_+_25598989	0.067	ENST00000454452.2	RHD	Rh blood group, D antigen
chr12_+_122880045	0.062	ENST00000539034.1 ENST00000535976.1	RP11-450K4.1	RP11-450K4.1
chr5_-_135290705	0.062	ENST00000274507.1	LECT2	leukocyte cell-derived chemotaxin 2
chr12_-_122879969	0.060	ENST00000540304.1	CLIP1	CAP-GLY domain containing linker protein 1
chr20_+_51588873	0.059	ENST00000371497.5	TSHZ2	teashirt zinc finger homeobox 2
chr15_+_59279851	0.057	ENST00000348370.4 ENST00000434298.1 ENST00000559160.1	RNF111	ring finger protein 111
chr4_+_15376165	0.056	ENST00000382383.3 ENST00000429690.1	C1QTNF7	C1q and tumor necrosis factor related protein 7
chr5_+_157602404	0.055	ENST00000522975.1	CTC-436K13.1	CTC-436K13.1
chr18_-_28742813	0.054	ENST00000257197.3 ENST00000257198.5	DSC1	desmocollin 1
chr1_+_174846570	0.053	ENST00000392064.2	RABGAP1L	RAB GTPase activating protein 1-like
chr9_+_33795533	0.050	ENST00000379405.3	PRSS3	protease, serine, 3
chr1_-_158656488	0.049	ENST00000368147.4	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr11_-_66206260	0.049	ENST00000329819.4 ENST00000310999.7 ENST00000430466.2	MRPL11	mitochondrial ribosomal protein L11
chr17_+_19314505	0.048	ENST00000461366.1	RNF112	ring finger protein 112
chr10_+_118305435	0.046	ENST00000369221.2	PNLIP	pancreatic lipase
chr1_-_226187013	0.045	ENST00000272091.7	SDE2	SDE2 telomere maintenance homolog (S. pombe)
chr15_+_81391740	0.044	ENST00000561216.1	C15orf26	chromosome 15 open reading frame 26
chr2_+_173792893	0.044	ENST00000535187.1	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr6_+_31674639	0.044	ENST00000556581.1 ENST00000375832.4 ENST00000503322.1	LY6G6F MEGT1	lymphocyte antigen 6 complex, locus G6F HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr2_+_44066101	0.041	ENST00000272286.2	ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8
chr12_+_109785708	0.040	ENST00000310903.5	MYO1H	myosin IH
chr1_+_161136180	0.040	ENST00000352210.5 ENST00000367999.4 ENST00000544598.1 ENST00000535223.1 ENST00000432542.2	PPOX	protoporphyrinogen oxidase
chr15_-_64126084	0.040	ENST00000560316.1 ENST00000443617.2 ENST00000560462.1 ENST00000558532.1 ENST00000561400.1	HERC1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr11_+_75428857	0.037	ENST00000198801.5	MOGAT2	monoacylglycerol O-acyltransferase 2
chr6_+_130339710	0.037	ENST00000526087.1 ENST00000533560.1 ENST00000361794.2	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr12_-_21928515	0.036	ENST00000537950.1	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr17_-_62084241	0.035	ENST00000449662.2	ICAM2	intercellular adhesion molecule 2
chr11_-_59612969	0.032	ENST00000541311.1 ENST00000257248.2	GIF	gastric intrinsic factor (vitamin B synthesis)
chr1_-_94050668	0.031	ENST00000539242.1	BCAR3	breast cancer anti-estrogen resistance 3
chr15_+_49715449	0.031	ENST00000560979.1	FGF7	fibroblast growth factor 7
chr20_+_31669333	0.031	ENST00000375483.3	BPIFB4	BPI fold containing family B, member 4
chr12_-_6233828	0.031	ENST00000572068.1 ENST00000261405.5	VWF	von Willebrand factor
chr22_-_29784519	0.028	ENST00000357586.2 ENST00000356015.2 ENST00000432560.2 ENST00000317368.7	AP1B1	adaptor-related protein complex 1, beta 1 subunit
chr12_-_54689532	0.027	ENST00000540264.2 ENST00000312156.4	NFE2	nuclear factor, erythroid 2
chr20_-_60294804	0.026	ENST00000317652.1	RP11-429E11.3	Uncharacterized protein
chr1_-_120354079	0.024	ENST00000354219.1 ENST00000369401.4 ENST00000256585.5	REG4	regenerating islet-derived family, member 4
chr16_+_53920795	0.021	ENST00000431610.2 ENST00000460382.1	FTO	fat mass and obesity associated
chr1_+_66999799	0.020	ENST00000371035.3 ENST00000371036.3 ENST00000371037.4	SGIP1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr2_+_220436917	0.020	ENST00000243786.2	INHA	inhibin, alpha
chr17_+_75283973	0.020	ENST00000431235.2 ENST00000449803.2	SEPT9	septin 9
chr12_+_111843749	0.019	ENST00000341259.2	SH2B3	SH2B adaptor protein 3
chr21_-_39870339	0.019	ENST00000429727.2 ENST00000398905.1 ENST00000398907.1 ENST00000453032.2 ENST00000288319.7	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog
chr5_-_33984786	0.019	ENST00000296589.4	SLC45A2	solute carrier family 45, member 2
chr19_+_36132631	0.018	ENST00000379026.2 ENST00000379023.4 ENST00000402764.2 ENST00000479824.1	ETV2	ets variant 2
chr1_-_205912577	0.018	ENST00000367135.3 ENST00000367134.2	SLC26A9	solute carrier family 26 (anion exchanger), member 9
chr3_+_88188254	0.017	ENST00000309495.5	ZNF654	zinc finger protein 654
chr20_+_43935474	0.017	ENST00000372743.1 ENST00000372741.3 ENST00000343694.3	RBPJL	recombination signal binding protein for immunoglobulin kappa J region-like
chr11_+_118958689	0.017	ENST00000535253.1 ENST00000392841.1	HMBS	hydroxymethylbilane synthase
chr14_-_23285011	0.016	ENST00000397532.3	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr22_+_35462129	0.015	ENST00000404699.2 ENST00000308700.6	ISX	intestine-specific homeobox
chr5_-_135290651	0.013	ENST00000522943.1 ENST00000514447.2	LECT2	leukocyte cell-derived chemotaxin 2
chr14_+_21945335	0.013	ENST00000262709.3 ENST00000457430.2 ENST00000448790.2	TOX4	TOX high mobility group box family member 4
chr3_-_47950745	0.012	ENST00000429422.1	MAP4	microtubule-associated protein 4
chr8_-_38008783	0.011	ENST00000276449.4	STAR	steroidogenic acute regulatory protein
chr20_-_54967187	0.011	ENST00000422322.1 ENST00000371356.2 ENST00000451915.1 ENST00000347343.2 ENST00000395911.1 ENST00000395907.1 ENST00000441357.1 ENST00000456249.1 ENST00000420474.1 ENST00000395909.4 ENST00000395914.1 ENST00000312783.6 ENST00000395915.3 ENST00000395913.3	AURKA	aurora kinase A
chr2_-_40739501	0.011	ENST00000403092.1 ENST00000402441.1 ENST00000448531.1	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr8_+_70404996	0.011	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr1_+_25598872	0.010	ENST00000328664.4	RHD	Rh blood group, D antigen
chr16_+_4475806	0.010	ENST00000262375.6 ENST00000355296.4 ENST00000431375.2 ENST00000574895.1	DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3
chr17_-_4806369	0.009	ENST00000293780.4	CHRNE	cholinergic receptor, nicotinic, epsilon (muscle)
chr5_+_1201703	0.009	ENST00000304460.10	SLC6A19	solute carrier family 6 (neutral amino acid transporter), member 19
chr14_-_23285069	0.008	ENST00000554758.1 ENST00000397528.4	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_-_93107443	0.007	ENST00000360348.2 ENST00000520428.1 ENST00000518992.1 ENST00000520556.1 ENST00000518317.1 ENST00000521319.1 ENST00000521375.1 ENST00000518449.1	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_-_11494975	0.007	ENST00000222139.6 ENST00000592375.2	EPOR	erythropoietin receptor
chr12_-_52995291	0.006	ENST00000293745.2 ENST00000354310.4	KRT72	keratin 72
chr20_-_30795511	0.006	ENST00000246229.4	PLAGL2	pleiomorphic adenoma gene-like 2
chr19_-_55549624	0.006	ENST00000417454.1 ENST00000310373.3 ENST00000333884.2	GP6	glycoprotein VI (platelet)
chr2_-_219850277	0.005	ENST00000295727.1	FEV	FEV (ETS oncogene family)
chr6_+_148593425	0.005	ENST00000367469.1	SASH1	SAM and SH3 domain containing 1
chr5_+_135496675	0.005	ENST00000507637.1	SMAD5	SMAD family member 5
chrX_+_107288197	0.004	ENST00000415430.3	VSIG1	V-set and immunoglobulin domain containing 1
chr14_-_23284703	0.004	ENST00000555911.1	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_-_90538397	0.004	ENST00000443397.3	RP11-685N3.1	Uncharacterized protein
chr1_+_171217677	0.003	ENST00000402921.2	FMO1	flavin containing monooxygenase 1
chr8_+_70378852	0.003	ENST00000525061.1 ENST00000458141.2 ENST00000260128.4	SULF1	sulfatase 1
chr12_-_56221330	0.002	ENST00000546837.1	RP11-762I7.5	Uncharacterized protein
chr6_-_30128657	0.002	ENST00000449742.2 ENST00000376704.3	TRIM10	tripartite motif containing 10
chrX_+_107288239	0.001	ENST00000217957.5	VSIG1	V-set and immunoglobulin domain containing 1
chr9_-_114937543	0.001	ENST00000374264.2 ENST00000374263.3	SUSD1	sushi domain containing 1
chr15_+_49715293	0.000	ENST00000267843.4 ENST00000560270.1	FGF7	fibroblast growth factor 7

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0046521	sphingoid catabolic process(GO:0046521)
0.1	0.4	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.1	GO:0030185	nitric oxide transport(GO:0030185) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0	0.2	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.0	0.5	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0071418	cellular response to amine stimulus(GO:0071418)
0.0	0.6	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.3	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.7	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.2	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.0	0.6	GO:0001891	phagocytic cup(GO:0001891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0002113	interleukin-33 binding(GO:0002113)
0.1	0.4	GO:0015265	urea channel activity(GO:0015265)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	0.3	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.2	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0	0.1	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.5	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS	Genes involved in Amine compound SLC transporters

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