Motif ID: GATA2

Z-value: 0.650


Transcription factors associated with GATA2:

Gene SymbolEntrez IDGene Name
GATA2 ENSG00000179348.7 GATA2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GATA2hg19_v2_chr3_-_128206759_1282067810.571.1e-01Click!


Activity profile for motif GATA2.

activity profile for motif GATA2


Sorted Z-values histogram for motif GATA2

Sorted Z-values for motif GATA2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_71533055 1.061 ENST00000552128.1
TSPAN8
tetraspanin 8
chr3_+_98250743 0.942 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr6_-_32557610 0.661 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr12_+_52643077 0.651 ENST00000553310.2
ENST00000544024.1
KRT86

keratin 86

chr12_-_71551652 0.617 ENST00000546561.1
TSPAN8
tetraspanin 8
chr2_+_42275153 0.616 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr11_+_34654011 0.566 ENST00000531794.1
EHF
ets homologous factor
chr5_+_150404904 0.554 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr1_+_81771806 0.491 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr5_-_75919217 0.478 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr11_+_134225909 0.445 ENST00000533324.1
GLB1L2
galactosidase, beta 1-like 2
chr7_-_121944491 0.441 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr2_-_190446738 0.434 ENST00000427419.1
ENST00000455320.1
SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

chr3_-_178969403 0.429 ENST00000314235.5
ENST00000392685.2
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr5_-_88180342 0.429 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chrX_+_38420623 0.408 ENST00000378482.2
TSPAN7
tetraspanin 7
chr20_+_12989596 0.396 ENST00000434210.1
ENST00000399002.2
SPTLC3

serine palmitoyltransferase, long chain base subunit 3

chr5_-_49737184 0.395 ENST00000508934.1
ENST00000303221.5
EMB

embigin

chr5_-_88179017 0.382 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C



myocyte enhancer factor 2C



chr6_-_32498046 0.367 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr7_+_1126437 0.365 ENST00000413368.1
ENST00000397092.1
GPER1

G protein-coupled estrogen receptor 1

chrX_+_105192423 0.361 ENST00000540278.1
NRK
Nik related kinase
chr4_-_168155700 0.351 ENST00000357545.4
ENST00000512648.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr2_-_207082748 0.351 ENST00000407325.2
ENST00000411719.1
GPR1

G protein-coupled receptor 1

chr4_-_168155730 0.350 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr17_-_15501932 0.347 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr2_+_33701286 0.337 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_+_129932974 0.328 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr20_+_12989822 0.328 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr4_-_168155577 0.327 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3





sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3





chr2_+_30454390 0.326 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH


limb bud and heart development


chr10_+_5135981 0.325 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr1_-_177133818 0.323 ENST00000424564.2
ENST00000361833.2
ASTN1

astrotactin 1

chr3_-_178976996 0.321 ENST00000485523.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr18_+_52385068 0.305 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr5_+_140579162 0.302 ENST00000536699.1
ENST00000354757.3
PCDHB11

protocadherin beta 11

chr5_-_75919253 0.299 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr2_+_210444142 0.297 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr15_-_33180439 0.296 ENST00000559610.1
FMN1
formin 1
chr9_+_12693336 0.292 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr9_+_118950325 0.292 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr6_+_36922209 0.290 ENST00000373674.3
PI16
peptidase inhibitor 16
chr2_-_235405168 0.288 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr5_-_88120151 0.288 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr6_-_47010061 0.287 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr19_+_18496957 0.286 ENST00000252809.3
GDF15
growth differentiation factor 15
chr7_+_1126461 0.285 ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr4_+_75310851 0.280 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr2_+_14772810 0.278 ENST00000295092.2
ENST00000331243.4
FAM84A

family with sequence similarity 84, member A

chr2_-_152118276 0.274 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr2_-_145188137 0.273 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr17_-_4689649 0.272 ENST00000441199.2
ENST00000416307.2
VMO1

vitelline membrane outer layer 1 homolog (chicken)

chr20_+_12989895 0.269 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr9_-_47314222 0.269 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2


AL953854.2


chr4_-_46911223 0.266 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr5_-_88119580 0.256 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr17_-_15502111 0.253 ENST00000354433.3
CDRT1
CMT1A duplicated region transcript 1
chr7_+_142498725 0.252 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr17_+_4402133 0.246 ENST00000329078.3
SPNS2
spinster homolog 2 (Drosophila)
chr10_-_99531709 0.243 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr4_-_87770416 0.242 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr1_-_177133998 0.242 ENST00000367657.3
ASTN1
astrotactin 1
chr11_-_65816591 0.241 ENST00000312006.4
GAL3ST3
galactose-3-O-sulfotransferase 3
chr1_-_11863571 0.238 ENST00000376583.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr11_-_110583912 0.235 ENST00000533353.1
ENST00000527598.1
ARHGAP20

Rho GTPase activating protein 20

chr10_-_90712520 0.234 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr5_+_143584814 0.233 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr1_+_154966058 0.229 ENST00000392487.1
LENEP
lens epithelial protein
chr22_+_21128167 0.227 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_-_121476750 0.227 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr12_+_71833550 0.226 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr10_-_56561022 0.224 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
PCDH15













protocadherin-related 15













chr2_+_131769256 0.223 ENST00000355771.3
ARHGEF4
Rho guanine nucleotide exchange factor (GEF) 4
chr17_-_29624343 0.223 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr2_-_179672142 0.222 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chr1_-_153517473 0.222 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr5_-_90610200 0.222 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
LUCAT1

RP11-213H15.4
lung cancer associated transcript 1 (non-protein coding)

RP11-213H15.4
chr10_+_24755416 0.219 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr6_+_69345166 0.218 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr19_-_50979981 0.217 ENST00000595790.1
ENST00000600100.1
FAM71E1

family with sequence similarity 71, member E1

chr11_+_74811578 0.217 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr4_-_73434498 0.217 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr17_-_72619869 0.215 ENST00000392619.1
ENST00000426295.2
CD300E

CD300e molecule

chr12_-_52779433 0.211 ENST00000257951.3
KRT84
keratin 84
chr5_+_143550396 0.211 ENST00000512467.1
KCTD16
potassium channel tetramerization domain containing 16
chr3_-_178103144 0.210 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1



RP11-33A14.1



chr9_+_77230499 0.208 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr11_-_36619771 0.207 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr4_-_76008706 0.206 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5

RP11-44F21.5

chr2_+_210443993 0.206 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr11_-_110583451 0.206 ENST00000260283.4
ENST00000528829.1
ARHGAP20

Rho GTPase activating protein 20

chr18_+_21464737 0.203 ENST00000586751.1
LAMA3
laminin, alpha 3
chr1_+_74701062 0.201 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr4_+_74301880 0.199 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr5_+_109218883 0.199 ENST00000523446.1
AC011366.3
Uncharacterized protein
chr7_-_16460863 0.198 ENST00000407010.2
ENST00000399310.3
ISPD

isoprenoid synthase domain containing

chr10_-_50970382 0.195 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr21_+_35552978 0.195 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310


long intergenic non-protein coding RNA 310


chr18_+_32173276 0.194 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr15_+_59910132 0.192 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_-_61734599 0.192 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr1_+_17559776 0.190 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1


peptidyl arginine deiminase, type I


chr2_+_149974684 0.188 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr4_+_89299994 0.186 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_+_184056614 0.185 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr1_+_180165672 0.185 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr8_-_86253888 0.184 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1


carbonic anhydrase I


chr8_+_24151553 0.184 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28


ADAM metallopeptidase domain 28


chr1_-_177134024 0.183 ENST00000367654.3
ASTN1
astrotactin 1
chr4_+_126237554 0.183 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr9_-_14180778 0.182 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr19_-_20048639 0.182 ENST00000595282.1
AC007204.1
Uncharacterized protein
chr9_+_19408919 0.182 ENST00000380376.1
ACER2
alkaline ceramidase 2
chr7_-_122339162 0.182 ENST00000340112.2
RNF133
ring finger protein 133
chr9_+_113431059 0.182 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr3_-_24207039 0.181 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr10_-_128359074 0.181 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr13_+_51913819 0.181 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr8_-_27468717 0.180 ENST00000520796.1
ENST00000520491.1
CLU

clusterin

chr5_-_88120083 0.180 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr5_-_115890554 0.180 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr4_-_48082192 0.179 ENST00000507351.1
TXK
TXK tyrosine kinase
chr11_-_10920714 0.179 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr5_-_55529115 0.178 ENST00000513241.2
ENST00000341048.4
ANKRD55

ankyrin repeat domain 55

chr1_-_11863171 0.178 ENST00000376592.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr4_+_89299885 0.176 ENST00000380265.5
ENST00000273960.3
HERC6

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

chr8_-_62559366 0.176 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr9_+_140122018 0.175 ENST00000445101.2
RNF224
ring finger protein 224
chr17_-_39156138 0.175 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr8_-_27468945 0.174 ENST00000405140.3
CLU
clusterin
chr2_-_163175133 0.174 ENST00000421365.2
ENST00000263642.2
IFIH1

interferon induced with helicase C domain 1

chrX_-_43832711 0.174 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr13_+_24144796 0.173 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr19_-_36545128 0.172 ENST00000538849.1
THAP8
THAP domain containing 8
chr5_-_100238918 0.169 ENST00000451528.2
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr12_-_13248732 0.169 ENST00000396302.3
GSG1
germ cell associated 1
chr17_-_15469590 0.169 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chrX_-_13835461 0.167 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr9_+_116267536 0.167 ENST00000374136.1
RGS3
regulator of G-protein signaling 3
chr6_+_46661575 0.167 ENST00000450697.1
TDRD6
tudor domain containing 6
chr1_+_183774285 0.167 ENST00000539189.1
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr2_+_210444298 0.166 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr1_-_145039835 0.165 ENST00000533259.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr5_+_140593509 0.164 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr3_+_69812701 0.163 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr4_-_168155417 0.163 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr12_-_13248562 0.161 ENST00000457134.2
ENST00000537302.1
GSG1

germ cell associated 1

chr2_+_169923577 0.160 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr8_-_17941575 0.160 ENST00000417108.2
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr3_-_182817367 0.160 ENST00000265594.4
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr2_+_28718921 0.160 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1


phospholipase B1


chr1_-_173020056 0.159 ENST00000239468.2
ENST00000404377.3
TNFSF18

tumor necrosis factor (ligand) superfamily, member 18

chr15_+_81225699 0.159 ENST00000560027.1
KIAA1199
KIAA1199
chr17_+_63133526 0.158 ENST00000443584.3
RGS9
regulator of G-protein signaling 9
chr1_+_11821844 0.158 ENST00000433342.1
C1orf167
chromosome 1 open reading frame 167
chr8_-_27468842 0.158 ENST00000523500.1
CLU
clusterin
chr18_+_32455201 0.157 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr20_+_34679725 0.157 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_+_183774240 0.157 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr10_+_105005644 0.155 ENST00000441178.2
RP11-332O19.5
ribulose-5-phosphate-3-epimerase-like 1
chr2_+_7017796 0.155 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr1_+_170115142 0.154 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr20_+_34802295 0.154 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_-_32908792 0.152 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr4_-_24914576 0.152 ENST00000502801.1
ENST00000428116.2
CCDC149

coiled-coil domain containing 149

chr13_+_24144509 0.152 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr10_+_24738355 0.150 ENST00000307544.6
KIAA1217
KIAA1217
chr9_+_12695702 0.149 ENST00000381136.2
TYRP1
tyrosinase-related protein 1
chr4_-_48136217 0.149 ENST00000264316.4
TXK
TXK tyrosine kinase
chr12_-_47219733 0.149 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4


solute carrier family 38, member 4


chr2_-_37068530 0.148 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr2_+_204192942 0.147 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr9_+_125512019 0.145 ENST00000373684.1
ENST00000304720.2
OR1L6

olfactory receptor, family 1, subfamily L, member 6

chr22_-_28392227 0.145 ENST00000431039.1
TTC28
tetratricopeptide repeat domain 28
chr2_-_197041193 0.143 ENST00000409228.1
STK17B
serine/threonine kinase 17b
chr5_+_140588269 0.142 ENST00000541609.1
ENST00000239450.2
PCDHB12

protocadherin beta 12

chr17_-_39942322 0.141 ENST00000449889.1
ENST00000465293.1
JUP

junction plakoglobin

chr10_-_128975273 0.140 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chr12_-_11287243 0.138 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr12_-_11139511 0.137 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr7_+_141478242 0.137 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr3_+_172468749 0.137 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
ECT2


epithelial cell transforming sequence 2 oncogene


chr12_+_75874580 0.135 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr2_-_190927447 0.135 ENST00000260950.4
MSTN
myostatin
chr2_-_211168332 0.135 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr10_-_14613968 0.134 ENST00000488576.1
ENST00000472095.1
FAM107B

family with sequence similarity 107, member B

chr4_+_84457529 0.134 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr3_+_69811858 0.134 ENST00000433517.1
MITF
microphthalmia-associated transcription factor
chr1_+_179335101 0.133 ENST00000508285.1
ENST00000511889.1
AXDND1

axonemal dynein light chain domain containing 1

chr2_+_219472637 0.133 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr5_-_100238956 0.132 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr2_+_219472488 0.131 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chr3_-_182817297 0.131 ENST00000539926.1
ENST00000476176.1
MCCC1

methylcrotonoyl-CoA carboxylase 1 (alpha)

chr2_+_201994042 0.130 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_206730484 0.130 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr3_-_180397256 0.130 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr4_+_76439095 0.130 ENST00000506261.1
THAP6
THAP domain containing 6
chr17_+_63096903 0.128 ENST00000582940.1
RP11-160O5.1
RP11-160O5.1
chr6_-_75828774 0.127 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr6_-_152639479 0.127 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.6 GO:2000724 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.2 0.8 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 0.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 0.3 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.4 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.4 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.5 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 1.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.1 0.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 1.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.3 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:2000502 negative regulation of lymphocyte chemotaxis(GO:1901624) negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.3 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:1902567 astrocyte chemotaxis(GO:0035700) negative regulation of eosinophil activation(GO:1902567) positive regulation of T cell extravasation(GO:2000409) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.1 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.0 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 1.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.0 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.0 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.0 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.0 0.0 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.0 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.0 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0042713 positive regulation of norepinephrine secretion(GO:0010701) response to anoxia(GO:0034059) sperm ejaculation(GO:0042713)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.0 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.0 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.0 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0045550 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.1 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.4 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.0 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.0 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.0 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport