Motif ID: FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.473


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXP1hg19_v2_chr3_-_71114066_71114114-0.713.2e-02Click!
FOXO1hg19_v2_chr13_-_41240717_412407350.383.2e-01Click!
FOXD1hg19_v2_chr5_-_72744336_72744359-0.294.5e-01Click!
FOXO6hg19_v2_chr1_+_41827594_418275940.039.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_54418598 1.284 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr12_-_71551652 1.281 ENST00000546561.1
TSPAN8
tetraspanin 8
chr12_-_71551868 1.128 ENST00000247829.3
TSPAN8
tetraspanin 8
chr17_+_72426891 1.053 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_+_72427477 1.005 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr7_-_95225768 0.876 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr9_+_118916082 0.791 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr2_+_33661382 0.743 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_-_29208183 0.732 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr7_-_121944491 0.713 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr8_+_31496809 0.629 ENST00000518104.1
ENST00000519301.1
NRG1

neuregulin 1

chr2_-_207078154 0.626 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr8_+_31497271 0.605 ENST00000520407.1
NRG1
neuregulin 1
chr11_+_34654011 0.591 ENST00000531794.1
EHF
ets homologous factor
chr7_+_114055052 0.557 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr19_-_58609570 0.539 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
ZSCAN18





zinc finger and SCAN domain containing 18





chr20_-_50179368 0.505 ENST00000609943.1
ENST00000609507.1
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr5_+_133451254 0.434 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7







transcription factor 7 (T-cell specific, HMG-box)







chr8_+_24151553 0.429 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28


ADAM metallopeptidase domain 28


chr2_-_207078086 0.423 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr6_+_125540951 0.403 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr2_-_145188137 0.391 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr6_-_32083106 0.380 ENST00000442721.1
TNXB
tenascin XB
chr6_+_101847105 0.379 ENST00000369137.3
ENST00000318991.6
GRIK2

glutamate receptor, ionotropic, kainate 2

chr3_+_178865887 0.369 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr17_-_29641104 0.368 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr10_+_75668916 0.367 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr18_+_3449330 0.365 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr17_-_29641084 0.364 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr17_-_39942940 0.342 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP



junction plakoglobin



chr17_+_72428218 0.326 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chrX_+_105936982 0.315 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr14_+_23067166 0.314 ENST00000216327.6
ENST00000542041.1
ABHD4

abhydrolase domain containing 4

chr6_-_56707943 0.310 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST




dystonin




chr20_+_10199468 0.294 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr14_+_23067146 0.293 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr20_-_22559211 0.277 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr3_+_181429704 0.272 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr3_-_185826718 0.271 ENST00000413301.1
ENST00000421809.1
ETV5

ets variant 5

chr2_-_233877912 0.271 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr9_+_140125385 0.262 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr8_+_24151620 0.261 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr6_-_42016385 0.257 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3





cyclin D3





chr4_-_40632605 0.257 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr12_-_24097236 0.256 ENST00000538083.1
SOX5
SRY (sex determining region Y)-box 5
chr3_-_185826855 0.251 ENST00000306376.5
ETV5
ets variant 5
chr2_-_198175495 0.249 ENST00000409153.1
ENST00000409919.1
ENST00000539527.1
ANKRD44


ankyrin repeat domain 44


chr1_-_207095324 0.245 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr19_+_18496957 0.241 ENST00000252809.3
GDF15
growth differentiation factor 15
chr4_-_105416039 0.239 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr13_-_67802549 0.238 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr10_-_92681033 0.237 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr17_+_72428266 0.222 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr10_-_13570533 0.215 ENST00000396900.2
ENST00000396898.2
BEND7

BEN domain containing 7

chr4_-_24914576 0.214 ENST00000502801.1
ENST00000428116.2
CCDC149

coiled-coil domain containing 149

chr8_+_26150628 0.214 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr6_+_26020672 0.214 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr4_+_86396321 0.213 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr6_-_152623231 0.213 ENST00000540663.1
ENST00000537033.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr18_+_3449695 0.213 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr1_-_207095212 0.205 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr6_+_32121908 0.205 ENST00000375143.2
ENST00000424499.1
PPT2

palmitoyl-protein thioesterase 2

chr8_-_33455268 0.204 ENST00000522982.1
DUSP26
dual specificity phosphatase 26 (putative)
chr6_+_32121789 0.203 ENST00000437001.2
ENST00000375137.2
PPT2

palmitoyl-protein thioesterase 2

chr2_+_33701286 0.202 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_+_120079478 0.202 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr4_-_40632757 0.201 ENST00000511902.1
ENST00000505220.1
RBM47

RNA binding motif protein 47

chr5_-_142782862 0.201 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_14028488 0.201 ENST00000405358.4
ETV1
ets variant 1
chr16_+_4421841 0.200 ENST00000304735.3
VASN
vasorin
chr2_+_33701707 0.200 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3


RAS guanyl releasing protein 3 (calcium and DAG-regulated)


chr4_-_168155169 0.197 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr3_+_178866199 0.196 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr1_-_151813033 0.195 ENST00000454109.1
C2CD4D
C2 calcium-dependent domain containing 4D
chr12_+_106696581 0.194 ENST00000547153.1
ENST00000299045.3
ENST00000546625.1
ENST00000553098.1
TCP11L2



t-complex 11, testis-specific-like 2



chr4_-_24914508 0.194 ENST00000504487.1
CCDC149
coiled-coil domain containing 149
chr6_-_32122106 0.193 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr2_+_158114051 0.192 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr4_-_40632844 0.190 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr8_+_99956759 0.190 ENST00000522510.1
ENST00000457907.2
OSR2

odd-skipped related transciption factor 2

chr5_-_38557561 0.189 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr20_+_10199566 0.186 ENST00000430336.1
SNAP25
synaptosomal-associated protein, 25kDa
chr3_+_187930491 0.185 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr18_-_2982869 0.184 ENST00000584915.1
LPIN2
lipin 2
chr2_+_189157536 0.183 ENST00000409580.1
ENST00000409637.3
GULP1

GULP, engulfment adaptor PTB domain containing 1

chr8_-_72274355 0.183 ENST00000388741.2
EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_56716686 0.182 ENST00000520645.1
DST
dystonin
chr6_+_122793058 0.182 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr3_+_172468749 0.181 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
ECT2


epithelial cell transforming sequence 2 oncogene


chrX_+_9880412 0.181 ENST00000418909.2
SHROOM2
shroom family member 2
chr3_+_187930429 0.180 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_69180083 0.179 ENST00000328895.4
GKN2
gastrokine 2
chr12_-_52779433 0.177 ENST00000257951.3
KRT84
keratin 84
chr6_-_46922659 0.176 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr3_+_172468505 0.176 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
ECT2




epithelial cell transforming sequence 2 oncogene




chr14_+_75761099 0.175 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5

RP11-293M10.5

chr1_-_201096312 0.174 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr2_+_189157498 0.174 ENST00000359135.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr8_-_72274095 0.173 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_124405681 0.172 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr5_-_42811986 0.172 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr9_+_140125209 0.172 ENST00000538474.1
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chrX_-_10851762 0.169 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr17_-_46035187 0.168 ENST00000300557.2
PRR15L
proline rich 15-like
chr6_+_97372645 0.167 ENST00000536676.1
ENST00000544166.1
KLHL32

kelch-like family member 32

chr12_+_13349711 0.167 ENST00000538364.1
ENST00000396301.3
EMP1

epithelial membrane protein 1

chr5_-_146833485 0.165 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chrX_+_106163626 0.164 ENST00000336803.1
CLDN2
claudin 2
chr3_+_187930719 0.164 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_+_1151573 0.163 ENST00000534821.1
ENST00000356191.2
MUC5AC

mucin 5AC, oligomeric mucus/gel-forming

chrX_+_9880590 0.162 ENST00000452575.1
SHROOM2
shroom family member 2
chr8_+_92261516 0.159 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr4_-_40632881 0.158 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr2_-_214016314 0.158 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr8_+_99956662 0.156 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2


odd-skipped related transciption factor 2


chr12_-_52715179 0.156 ENST00000293670.3
KRT83
keratin 83
chr6_+_74405501 0.155 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr17_+_67410832 0.155 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_+_86396265 0.154 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr12_+_13349650 0.153 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr6_-_27880174 0.152 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr2_+_175260451 0.151 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3



secernin 3



chr2_+_197577841 0.150 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr3_+_187957646 0.150 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_-_142783175 0.150 ENST00000231509.3
ENST00000394464.2
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr5_+_169064245 0.147 ENST00000256935.8
DOCK2
dedicator of cytokinesis 2
chr6_-_34524093 0.146 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr14_+_56584414 0.142 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr4_+_88720698 0.142 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr2_+_111878483 0.140 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11




BCL2-like 11 (apoptosis facilitator)




chr6_-_34524049 0.139 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr5_+_121465207 0.139 ENST00000296600.4
ZNF474
zinc finger protein 474
chr3_-_168865522 0.138 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr8_-_72274467 0.137 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr6_+_33168189 0.136 ENST00000444757.1
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr5_+_140602904 0.136 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr12_-_53343560 0.136 ENST00000548998.1
KRT8
keratin 8
chr1_+_87797351 0.136 ENST00000370542.1
LMO4
LIM domain only 4
chr4_-_74486217 0.135 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr4_-_74486109 0.134 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_74405804 0.134 ENST00000287097.5
CD109
CD109 molecule
chr2_+_149402989 0.133 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_-_131132658 0.132 ENST00000511848.1
ENST00000510461.1
ENST00000514667.1
FNIP1

CTC-432M15.3
folliculin interacting protein 1

Folliculin-interacting protein 1
chr5_-_115872142 0.131 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr4_+_108745711 0.128 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr9_+_118950325 0.126 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_-_53343602 0.126 ENST00000546897.1
ENST00000552551.1
KRT8

keratin 8

chr1_+_104104379 0.126 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr3_+_172468472 0.126 ENST00000232458.5
ENST00000392692.3
ECT2

epithelial cell transforming sequence 2 oncogene

chr5_-_131132614 0.126 ENST00000307968.7
ENST00000307954.8
FNIP1

folliculin interacting protein 1

chr12_+_53491220 0.126 ENST00000548547.1
ENST00000301464.3
IGFBP6

insulin-like growth factor binding protein 6

chr2_+_175260514 0.125 ENST00000424069.1
ENST00000427038.1
SCRN3

secernin 3

chr1_-_8585945 0.124 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chrX_-_48937503 0.124 ENST00000322995.8
WDR45
WD repeat domain 45
chr8_+_22132810 0.122 ENST00000356766.6
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr8_-_27469383 0.120 ENST00000519742.1
CLU
clusterin
chr1_-_12677714 0.119 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chrX_-_15619076 0.119 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr4_+_86525299 0.119 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr10_+_80008505 0.116 ENST00000434974.1
ENST00000423770.1
ENST00000432742.1
LINC00856


long intergenic non-protein coding RNA 856


chr10_+_18689637 0.116 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_42418999 0.113 ENST00000340840.2
ENST00000354325.2
TRERF1

transcriptional regulating factor 1

chr3_+_69985734 0.113 ENST00000314557.6
ENST00000394351.3
MITF

microphthalmia-associated transcription factor

chr12_-_53343633 0.113 ENST00000546826.1
KRT8
keratin 8
chr2_-_145275828 0.112 ENST00000392861.2
ENST00000409211.1
ZEB2

zinc finger E-box binding homeobox 2

chrX_-_48937684 0.111 ENST00000465382.1
ENST00000423215.2
WDR45

WD repeat domain 45

chr1_+_164528437 0.110 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr19_+_16435625 0.110 ENST00000248071.5
ENST00000592003.1
KLF2

Kruppel-like factor 2

chr22_-_37505588 0.110 ENST00000406856.1
TMPRSS6
transmembrane protease, serine 6
chr2_+_198380763 0.110 ENST00000448447.2
ENST00000409360.1
MOB4

MOB family member 4, phocein

chr5_+_137673200 0.109 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr4_+_57276661 0.109 ENST00000598320.1
AC068620.1
Uncharacterized protein
chrX_+_49019061 0.108 ENST00000376339.1
ENST00000425661.2
ENST00000458388.1
ENST00000412696.2
MAGIX



MAGI family member, X-linked



chr1_-_8586084 0.108 ENST00000464972.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr3_+_69985792 0.108 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr10_+_24755416 0.107 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr1_+_3541543 0.107 ENST00000378344.2
ENST00000344579.5
TPRG1L

tumor protein p63 regulated 1-like

chr20_+_2082494 0.107 ENST00000246032.3
STK35
serine/threonine kinase 35
chr6_+_97372734 0.107 ENST00000539200.1
KLHL32
kelch-like family member 32
chrX_-_106146547 0.106 ENST00000276173.4
ENST00000411805.1
RIPPLY1

ripply transcriptional repressor 1

chr10_-_90751038 0.106 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr6_-_30043539 0.104 ENST00000376751.3
ENST00000244360.6
RNF39

ring finger protein 39

chr16_+_57680840 0.104 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56


G protein-coupled receptor 56


chr1_+_185703513 0.103 ENST00000271588.4
ENST00000367492.2
HMCN1

hemicentin 1

chr4_+_90032651 0.103 ENST00000603357.1
RP11-84C13.1
RP11-84C13.1
chr15_-_34610962 0.103 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr3_+_185046676 0.101 ENST00000428617.1
ENST00000443863.1
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr2_+_177053307 0.100 ENST00000331462.4
HOXD1
homeobox D1
chr7_+_139528952 0.100 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1



thromboxane A synthase 1 (platelet)



chrX_-_48937531 0.100 ENST00000473974.1
ENST00000475880.1
ENST00000396681.4
ENST00000553851.1
ENST00000471338.1
ENST00000476728.1
ENST00000376368.2
ENST00000485908.1
ENST00000376372.3
ENST00000376358.3
WDR45








AF196779.12
WD repeat domain 45








WD repeat domain phosphoinositide-interacting protein 4
chr4_+_187148556 0.099 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr9_-_39288092 0.098 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3



contactin associated protein-like 3



chr16_+_57680811 0.098 ENST00000569101.1
GPR56
G protein-coupled receptor 56
chr2_-_145275228 0.096 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2



zinc finger E-box binding homeobox 2



chr2_-_175260368 0.096 ENST00000342016.3
ENST00000362053.5
CIR1

corepressor interacting with RBPJ, 1

chr14_-_73493825 0.096 ENST00000318876.5
ENST00000556143.1
ZFYVE1

zinc finger, FYVE domain containing 1

chr6_+_97372596 0.095 ENST00000369261.4
KLHL32
kelch-like family member 32
chr3_-_19975665 0.094 ENST00000295824.9
ENST00000389256.4
EFHB

EF-hand domain family, member B

chr4_+_76871883 0.094 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr18_+_21529811 0.094 ENST00000588004.1
LAMA3
laminin, alpha 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 0.6 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.6 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.3 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.7 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.2 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.3 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.3 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.3 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 2.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0072143 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.4 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:0072135 kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.0 GO:0072071 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.0 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0001768 establishment of T cell polarity(GO:0001768)
0.0 0.0 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.0 0.1 GO:1903961 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0070701 mucus layer(GO:0070701)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0097444 spine apparatus(GO:0097444)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 3.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.8 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.6 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.2 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity