Motif ID: FOXA2_FOXJ3

Z-value: 0.769

Transcription factors associated with FOXA2_FOXJ3:

Gene SymbolEntrez IDGene Name
FOXA2 ENSG00000125798.10 FOXA2
FOXJ3 ENSG00000198815.4 FOXJ3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXA2hg19_v2_chr20_-_22565101_22565223-0.909.5e-04Click!
FOXJ3hg19_v2_chr1_-_42801540_428015620.826.7e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2_FOXJ3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_74120094 1.296 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2




actin, gamma 2, smooth muscle, enteric




chr8_-_16424871 1.154 ENST00000518026.1
MSR1
macrophage scavenger receptor 1
chr3_+_164924716 1.009 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2

RP11-85M11.2

chr13_-_46756351 0.998 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_153599269 0.970 ENST00000463297.1
RP11-217E22.5
RP11-217E22.5
chr3_-_157221128 0.842 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr17_-_41985096 0.826 ENST00000269095.4
ENST00000523220.1
MPP2

membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)

chr1_+_59486129 0.752 ENST00000438195.1
ENST00000424308.1
RP4-794H19.4

RP4-794H19.4

chr8_+_36641842 0.733 ENST00000523973.1
ENST00000399881.3
KCNU1

potassium channel, subfamily U, member 1

chr12_+_54378923 0.724 ENST00000303460.4
HOXC10
homeobox C10
chr20_+_45338126 0.718 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chrX_+_16668278 0.660 ENST00000380200.3
S100G
S100 calcium binding protein G
chr2_-_202563414 0.619 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
MPP4


membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)


chr2_-_202563351 0.596 ENST00000602867.1
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr20_+_58630972 0.596 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr12_-_71031185 0.529 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr19_-_39826639 0.527 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr6_+_12717892 0.523 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr12_+_54378849 0.522 ENST00000515593.1
HOXC10
homeobox C10
chr7_+_106505696 0.497 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr11_-_26593677 0.484 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr21_-_16374688 0.482 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr11_-_26593779 0.479 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr6_+_12958137 0.468 ENST00000457702.2
ENST00000379345.2
PHACTR1

phosphatase and actin regulator 1

chr7_+_106505912 0.440 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr2_-_71454185 0.421 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr15_-_74658493 0.420 ENST00000419019.2
ENST00000569662.1
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr11_-_26593649 0.410 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr10_-_4285923 0.392 ENST00000418372.1
ENST00000608792.1
LINC00702

long intergenic non-protein coding RNA 702

chr10_+_33271469 0.381 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chr15_-_74658519 0.361 ENST00000450547.1
ENST00000358632.4
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr10_-_14050522 0.359 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr16_-_30064244 0.358 ENST00000571269.1
ENST00000561666.1
FAM57B

family with sequence similarity 57, member B

chr5_+_159614374 0.358 ENST00000393980.4
FABP6
fatty acid binding protein 6, ileal
chr10_-_4285835 0.355 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr15_+_69857515 0.342 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr5_-_9712312 0.340 ENST00000506620.1
ENST00000514078.1
ENST00000606744.1
TAS2R1

CTD-2143L24.1
taste receptor, type 2, member 1

CTD-2143L24.1
chr5_+_167181917 0.327 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr5_+_166711804 0.326 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr4_+_104346194 0.322 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr12_+_20968608 0.315 ENST00000553473.1
ENST00000554957.1
ENST00000381541.3
ENST00000540229.1
SLCO1B3
SLCO1B7
LST3

solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein

chr1_+_86064794 0.309 ENST00000426794.1
RP11-290M5.2
RP11-290M5.2
chrX_-_133792480 0.309 ENST00000359237.4
PLAC1
placenta-specific 1
chr3_+_159570722 0.308 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr12_-_15038779 0.308 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr10_-_61899124 0.300 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr5_+_167182003 0.299 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr12_-_12837423 0.295 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr2_+_88047606 0.295 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr20_+_44035200 0.295 ENST00000372717.1
ENST00000360981.4
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr1_+_221054411 0.294 ENST00000427693.1
HLX
H2.0-like homeobox
chr3_-_100551141 0.284 ENST00000478235.1
ENST00000471901.1
ABI3BP

ABI family, member 3 (NESH) binding protein

chr2_+_65283529 0.284 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
CEP68


centrosomal protein 68kDa


chr2_+_65283506 0.283 ENST00000377990.2
CEP68
centrosomal protein 68kDa
chr7_-_38389573 0.279 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr10_+_70847852 0.272 ENST00000242465.3
SRGN
serglycin
chr1_+_77333117 0.265 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr1_+_172745006 0.265 ENST00000432694.2
RP1-15D23.2
RP1-15D23.2
chr6_+_21666633 0.265 ENST00000606851.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr5_+_156607829 0.264 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr14_+_37126765 0.263 ENST00000402703.2
PAX9
paired box 9
chr1_+_150122034 0.262 ENST00000025469.6
ENST00000369124.4
PLEKHO1

pleckstrin homology domain containing, family O member 1

chr1_+_66796401 0.261 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_129375556 0.258 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr4_-_174256276 0.253 ENST00000296503.5
HMGB2
high mobility group box 2
chr4_+_15376165 0.252 ENST00000382383.3
ENST00000429690.1
C1QTNF7

C1q and tumor necrosis factor related protein 7

chr9_-_4299874 0.249 ENST00000381971.3
ENST00000477901.1
GLIS3

GLIS family zinc finger 3

chr12_+_76653682 0.246 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr6_-_131321863 0.245 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_+_164924769 0.242 ENST00000494915.1
RP11-85M11.2
RP11-85M11.2
chr2_+_58655461 0.238 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr1_+_221054584 0.235 ENST00000549319.1
HLX
H2.0-like homeobox
chr6_-_131211534 0.233 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr5_-_19988288 0.231 ENST00000502796.1
ENST00000511273.1
CDH18

cadherin 18, type 2

chr1_+_59486059 0.221 ENST00000447329.1
RP4-794H19.4
RP4-794H19.4
chr6_-_161085291 0.220 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr16_+_11439286 0.217 ENST00000312499.5
ENST00000576027.1
RMI2

RecQ mediated genome instability 2

chr12_-_92539614 0.215 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr1_-_246729544 0.210 ENST00000544618.1
ENST00000366514.4
TFB2M

transcription factor B2, mitochondrial

chr5_-_19988339 0.210 ENST00000382275.1
CDH18
cadherin 18, type 2
chr12_-_102591604 0.205 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr8_-_100025238 0.205 ENST00000521696.1
RP11-410L14.2
RP11-410L14.2
chr22_-_17302589 0.203 ENST00000331428.5
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr1_+_174846570 0.202 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr16_+_10479906 0.201 ENST00000562527.1
ENST00000396560.2
ENST00000396559.1
ENST00000562102.1
ENST00000543967.1
ENST00000569939.1
ENST00000569900.1
ATF7IP2






activating transcription factor 7 interacting protein 2






chr4_+_147096837 0.201 ENST00000296581.5
ENST00000502781.1
LSM6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr3_+_119298523 0.198 ENST00000357003.3
ADPRH
ADP-ribosylarginine hydrolase
chr3_-_150421728 0.198 ENST00000295910.6
ENST00000491361.1
FAM194A

family with sequence similarity 194, member A

chr12_+_79439405 0.197 ENST00000552744.1
SYT1
synaptotagmin I
chr8_+_11666649 0.195 ENST00000528643.1
ENST00000525777.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr15_-_40600111 0.194 ENST00000543785.2
ENST00000260402.3
PLCB2

phospholipase C, beta 2

chrX_-_122756660 0.194 ENST00000441692.1
THOC2
THO complex 2
chr12_+_54892550 0.194 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr15_-_40600026 0.192 ENST00000456256.2
ENST00000557821.1
PLCB2

phospholipase C, beta 2

chr20_+_44035847 0.191 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_-_80782219 0.190 ENST00000553594.1
DIO2
deiodinase, iodothyronine, type II
chr4_-_186570679 0.186 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr12_-_12714025 0.185 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr11_+_110225855 0.183 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1

RP11-347E10.1

chr4_-_186456652 0.181 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr5_+_54398463 0.180 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr10_+_97759848 0.180 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B


coiled-coil and C2 domain containing 2B


chr2_+_68592305 0.180 ENST00000234313.7
PLEK
pleckstrin
chr2_-_65593784 0.178 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr12_+_76653611 0.176 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr1_-_89736434 0.175 ENST00000370459.3
GBP5
guanylate binding protein 5
chr6_+_37012607 0.175 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr5_-_59064458 0.175 ENST00000502575.1
ENST00000507116.1
PDE4D

phosphodiesterase 4D, cAMP-specific

chr15_+_99433570 0.174 ENST00000558898.1
IGF1R
insulin-like growth factor 1 receptor
chr8_-_116673894 0.174 ENST00000395713.2
TRPS1
trichorhinophalangeal syndrome I
chr3_-_127455200 0.174 ENST00000398101.3
MGLL
monoglyceride lipase
chr4_+_146403912 0.174 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1


SMAD family member 1


chr14_+_97263641 0.174 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr9_-_140142222 0.173 ENST00000344774.4
ENST00000388932.2
FAM166A

family with sequence similarity 166, member A

chr2_-_56274461 0.169 ENST00000446139.1
AC011306.2
AC011306.2
chr6_+_4087664 0.168 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr16_-_71323617 0.167 ENST00000563876.1
CMTR2
cap methyltransferase 2
chr16_-_88772670 0.166 ENST00000562544.1
RNF166
ring finger protein 166
chr16_+_53469525 0.166 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr9_-_140196703 0.165 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr12_-_71031220 0.164 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr6_-_32160622 0.164 ENST00000487761.1
ENST00000375040.3
GPSM3

G-protein signaling modulator 3

chr6_-_88032795 0.163 ENST00000296882.3
GJB7
gap junction protein, beta 7, 25kDa
chr9_-_16215897 0.163 ENST00000433347.1
C9orf92
chromosome 9 open reading frame 92
chr4_-_186456766 0.160 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr7_+_26332645 0.159 ENST00000396376.1
SNX10
sorting nexin 10
chr9_-_16253112 0.159 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr12_-_7596735 0.158 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1


CD163 molecule-like 1


chr19_-_48613820 0.157 ENST00000596352.1
PLA2G4C
phospholipase A2, group IVC (cytosolic, calcium-independent)
chr1_+_81106951 0.157 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr8_+_67344710 0.157 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1


alcohol dehydrogenase, iron containing, 1


chr5_-_36301984 0.157 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L


RAN binding protein 3-like


chr9_+_136287444 0.156 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr2_+_61372226 0.155 ENST00000426997.1
C2orf74
chromosome 2 open reading frame 74
chr8_+_101349823 0.154 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr6_+_62284008 0.153 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr3_-_151102529 0.149 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr12_-_106480587 0.148 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr3_+_39448180 0.147 ENST00000301821.6
ENST00000458478.1
ENST00000443003.1
RPSA


ribosomal protein SA


chr1_+_178310581 0.147 ENST00000462775.1
RASAL2
RAS protein activator like 2
chr15_+_57998923 0.145 ENST00000380557.4
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr3_-_156272872 0.144 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr15_+_54903673 0.143 ENST00000560537.1
UNC13C
unc-13 homolog C (C. elegans)
chr10_+_78078088 0.142 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr12_-_76462713 0.140 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr3_+_119298429 0.140 ENST00000478927.1
ADPRH
ADP-ribosylarginine hydrolase
chr9_-_136933615 0.139 ENST00000371834.2
BRD3
bromodomain containing 3
chr1_-_16400086 0.139 ENST00000375662.4
FAM131C
family with sequence similarity 131, member C
chr15_-_31283798 0.136 ENST00000435680.1
ENST00000425768.1
MTMR10

myotubularin related protein 10

chr6_+_43112037 0.136 ENST00000473339.1
PTK7
protein tyrosine kinase 7
chr13_-_103451307 0.136 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr6_+_134758827 0.135 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chrX_-_108725301 0.134 ENST00000218006.2
GUCY2F
guanylate cyclase 2F, retinal
chr1_+_86934526 0.134 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr15_-_81616446 0.130 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr12_-_12714006 0.130 ENST00000541207.1
DUSP16
dual specificity phosphatase 16
chr17_+_7487146 0.130 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1





mannose-P-dolichol utilization defect 1





chr3_-_58523010 0.129 ENST00000459701.2
ENST00000302819.5
ACOX2

acyl-CoA oxidase 2, branched chain

chr13_-_79980315 0.129 ENST00000438737.2
RBM26
RNA binding motif protein 26
chr4_+_117220016 0.128 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr15_+_78857870 0.128 ENST00000559554.1
CHRNA5
cholinergic receptor, nicotinic, alpha 5 (neuronal)
chr9_+_70856397 0.128 ENST00000360171.6
CBWD3
COBW domain containing 3
chr1_-_238108575 0.127 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr2_-_86422523 0.127 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT


inner membrane protein, mitochondrial


chrX_+_26156460 0.127 ENST00000325250.1
MAGEB18
melanoma antigen family B, 18
chr15_+_78857849 0.126 ENST00000299565.5
CHRNA5
cholinergic receptor, nicotinic, alpha 5 (neuronal)
chr16_+_84801852 0.126 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr14_+_77425972 0.126 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr21_-_33975547 0.124 ENST00000431599.1
C21orf59
chromosome 21 open reading frame 59
chr9_+_126131131 0.124 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr15_-_65321943 0.124 ENST00000220058.4
MTFMT
mitochondrial methionyl-tRNA formyltransferase
chr9_-_70490107 0.124 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5




COBW domain containing 5




chr3_-_156272924 0.124 ENST00000467789.1
ENST00000265044.2
SSR3

signal sequence receptor, gamma (translocon-associated protein gamma)

chr17_+_67590125 0.123 ENST00000591334.1
AC003051.1
AC003051.1
chr16_+_77233294 0.120 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr13_+_41885341 0.120 ENST00000379406.3
ENST00000379367.3
ENST00000403412.3
NAA16


N(alpha)-acetyltransferase 16, NatA auxiliary subunit


chr20_-_1165319 0.118 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr10_-_50396357 0.114 ENST00000453436.1
ENST00000474718.1
C10orf128

chromosome 10 open reading frame 128

chr6_-_114194483 0.114 ENST00000434296.2
RP1-249H1.4
RP1-249H1.4
chr3_+_151591422 0.113 ENST00000362032.5
SUCNR1
succinate receptor 1
chr11_-_34535297 0.112 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr17_+_71229346 0.112 ENST00000535032.2
ENST00000582793.1
C17orf80

chromosome 17 open reading frame 80

chr6_-_131291572 0.112 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr12_-_56367101 0.112 ENST00000549233.2
PMEL
premelanosome protein
chr18_-_53069419 0.111 ENST00000570177.2
TCF4
transcription factor 4
chr19_-_48614063 0.110 ENST00000599921.1
ENST00000599111.1
PLA2G4C

phospholipase A2, group IVC (cytosolic, calcium-independent)

chr1_+_203765437 0.108 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr1_-_16763685 0.107 ENST00000540400.1
SPATA21
spermatogenesis associated 21
chr15_+_64680003 0.105 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr14_+_100070869 0.105 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr10_+_62538089 0.104 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1


cyclin-dependent kinase 1


chr8_+_103991013 0.104 ENST00000517983.1
KB-1507C5.4
KB-1507C5.4
chr16_+_66442411 0.103 ENST00000499966.1
LINC00920
long intergenic non-protein coding RNA 920
chr6_-_2751146 0.103 ENST00000268446.5
ENST00000274643.7
MYLK4

myosin light chain kinase family, member 4

chr3_-_135916073 0.103 ENST00000481989.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr19_-_48614033 0.103 ENST00000354276.3
PLA2G4C
phospholipase A2, group IVC (cytosolic, calcium-independent)
chr5_+_61708488 0.103 ENST00000505902.1
IPO11
importin 11
chr6_-_131949200 0.101 ENST00000539158.1
ENST00000368058.1
MED23

mediator complex subunit 23

chr1_+_227127981 0.101 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3


aarF domain containing kinase 3


chr7_-_23571586 0.101 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
TRA2A


transformer 2 alpha homolog (Drosophila)



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.5 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.2 GO:0072616 interleukin-18 secretion(GO:0072616)
0.1 0.2 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0015993 molecular hydrogen transport(GO:0015993)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 1.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.5 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.9 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 1.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.5 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.8 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0030656 regulation of vitamin metabolic process(GO:0030656)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.0 GO:0032707 detection of lipopolysaccharide(GO:0032497) negative regulation of interleukin-23 production(GO:0032707)
0.0 0.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.1 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.7 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0090669 interferon-alpha secretion(GO:0072642) telomerase RNA stabilization(GO:0090669) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.0 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.0 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.0 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.4 GO:0032982 myosin filament(GO:0032982)
0.0 1.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.7 GO:0042731 PH domain binding(GO:0042731)
0.1 0.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0097003 adiponectin binding(GO:0055100) adipokinetic hormone receptor activity(GO:0097003)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.9 REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease