Motif ID: FLI1

Z-value: 0.483


Transcription factors associated with FLI1:

Gene SymbolEntrez IDGene Name
FLI1 ENSG00000151702.12 FLI1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FLI1hg19_v2_chr11_+_128563652_128563689-0.137.4e-01Click!


Activity profile for motif FLI1.

activity profile for motif FLI1


Sorted Z-values histogram for motif FLI1

Sorted Z-values for motif FLI1



Network of associatons between targets according to the STRING database.



First level regulatory network of FLI1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_161039647 1.044 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr1_-_161039456 1.005 ENST00000368016.3
ARHGAP30
Rho GTPase activating protein 30
chr3_-_121379739 0.999 ENST00000428394.2
ENST00000314583.3
HCLS1

hematopoietic cell-specific Lyn substrate 1

chr1_-_161039753 0.585 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr9_-_130617029 0.515 ENST00000373203.4
ENG
endoglin
chr7_+_106505696 0.506 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr9_-_130616915 0.503 ENST00000344849.3
ENG
endoglin
chr15_+_23810903 0.495 ENST00000564592.1
MKRN3
makorin ring finger protein 3
chr14_+_88471468 0.483 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr14_+_96087251 0.453 ENST00000555032.1
RP11-1070N10.5
RP11-1070N10.5
chr14_+_63671105 0.406 ENST00000316754.3
RHOJ
ras homolog family member J
chr18_+_43405471 0.398 ENST00000389474.3
SIGLEC15
sialic acid binding Ig-like lectin 15
chr7_+_106505912 0.387 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr14_+_63671577 0.371 ENST00000555125.1
RHOJ
ras homolog family member J
chr22_+_27068766 0.352 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5



CTA-211A9.5



chr1_-_156786634 0.304 ENST00000392306.2
ENST00000368199.3
SH2D2A

SH2 domain containing 2A

chr17_+_76422409 0.300 ENST00000600087.1
AC061992.1
Uncharacterized protein
chr19_-_54567159 0.296 ENST00000338372.2
ENST00000376626.1
VSTM1

V-set and transmembrane domain containing 1

chr1_-_156786530 0.291 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr14_+_100531738 0.289 ENST00000555706.1
EVL
Enah/Vasp-like
chr4_+_153021899 0.283 ENST00000509332.1
ENST00000504144.1
ENST00000499452.2
RP11-18H21.1


RP11-18H21.1


chr17_+_4336955 0.274 ENST00000355530.2
SPNS3
spinster homolog 3 (Drosophila)
chr5_+_39520499 0.269 ENST00000604954.1
CTD-2078B5.2
CTD-2078B5.2
chr6_-_169654139 0.266 ENST00000366787.3
THBS2
thrombospondin 2
chr20_+_58630972 0.256 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr7_+_150020329 0.250 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr12_+_50690489 0.247 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr14_+_100531615 0.243 ENST00000392920.3
EVL
Enah/Vasp-like
chr19_+_41281060 0.243 ENST00000594436.1
ENST00000597784.1
MIA

melanoma inhibitory activity

chr17_+_4337199 0.243 ENST00000333476.2
SPNS3
spinster homolog 3 (Drosophila)
chr19_+_41281282 0.238 ENST00000263369.3
MIA
melanoma inhibitory activity
chr7_+_150020363 0.234 ENST00000359623.4
ENST00000493307.1
LRRC61

leucine rich repeat containing 61

chr16_-_3493528 0.232 ENST00000301744.4
ZNF597
zinc finger protein 597
chr12_+_94071341 0.218 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr22_+_27068704 0.212 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5


CTA-211A9.5


chr17_+_47287749 0.211 ENST00000419580.2
ABI3
ABI family, member 3
chr5_-_150284351 0.208 ENST00000427179.1
ZNF300
zinc finger protein 300
chr5_-_150284532 0.207 ENST00000394226.2
ENST00000446148.2
ENST00000274599.5
ENST00000418587.2
ZNF300



zinc finger protein 300



chr19_-_51192661 0.205 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr1_-_238649319 0.195 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr3_+_148583043 0.191 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr14_+_52327109 0.189 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr6_-_133084580 0.178 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2


vanin 2


chr3_-_149051194 0.178 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr7_-_140340098 0.177 ENST00000477488.1
DENND2A
DENN/MADD domain containing 2A
chr1_+_59486129 0.177 ENST00000438195.1
ENST00000424308.1
RP4-794H19.4

RP4-794H19.4

chr6_-_31550192 0.174 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr18_+_72265084 0.172 ENST00000582337.1
ZNF407
zinc finger protein 407
chr7_-_150020216 0.172 ENST00000477367.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr19_+_41281416 0.171 ENST00000597140.1
MIA
melanoma inhibitory activity
chr12_-_15082050 0.171 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr9_+_138413277 0.170 ENST00000263598.2
ENST00000371781.3
LCN1

lipocalin 1

chr6_+_13182751 0.170 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr12_+_94071129 0.170 ENST00000552983.1
ENST00000332896.3
ENST00000552033.1
ENST00000548483.1
CRADD



CASP2 and RIPK1 domain containing adaptor with death domain



chr11_+_131781290 0.169 ENST00000425719.2
ENST00000374784.1
NTM

neurotrimin

chr12_+_76653682 0.167 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr3_-_195310802 0.162 ENST00000421243.1
ENST00000453131.1
APOD

apolipoprotein D

chr20_+_44746939 0.162 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr18_+_61420169 0.161 ENST00000425392.1
ENST00000336429.2
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr3_-_128879875 0.160 ENST00000393292.3
ENST00000273541.8
ENST00000418265.1
ISY1

ISY1-RAB43
ISY1 splicing factor homolog (S. cerevisiae)

ISY1-RAB43 readthrough
chr11_-_7698453 0.156 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr4_+_7940728 0.154 ENST00000429019.3
AC097381.1
AC097381.1
chr10_+_102106829 0.152 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_-_46682321 0.152 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr10_+_69865866 0.151 ENST00000354393.2
MYPN
myopalladin
chr4_-_153601136 0.149 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr1_+_120049826 0.149 ENST00000369413.3
ENST00000235547.6
ENST00000528909.1
HSD3B1


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1


chr13_+_107028897 0.145 ENST00000439790.1
ENST00000435024.1
LINC00460

long intergenic non-protein coding RNA 460

chr22_+_45098067 0.145 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
PRR5


PRR5-ARHGAP8
proline rich 5 (renal)


PRR5-ARHGAP8 readthrough
chrX_+_135230712 0.145 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr16_+_20817746 0.145 ENST00000568894.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr6_+_7541808 0.144 ENST00000379802.3
DSP
desmoplakin
chr4_-_185303418 0.144 ENST00000610223.1
ENST00000608785.1
RP11-290F5.1

RP11-290F5.1

chr19_-_10628117 0.143 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr14_+_52327350 0.140 ENST00000555472.1
ENST00000556766.1
GNG2

guanine nucleotide binding protein (G protein), gamma 2

chr11_+_7598239 0.139 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr18_+_44812072 0.138 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1

CTD-2130O13.1

chr12_+_58005204 0.136 ENST00000286494.4
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr7_-_143892748 0.134 ENST00000378115.2
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr19_-_54567035 0.129 ENST00000366170.2
ENST00000425006.2
VSTM1

V-set and transmembrane domain containing 1

chr22_-_24181174 0.129 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3



derlin 3



chr9_-_102582155 0.129 ENST00000427039.1
RP11-554F20.1
RP11-554F20.1
chr19_-_10628098 0.129 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr7_-_1781906 0.129 ENST00000453348.1
ENST00000415399.1
AC074389.9

AC074389.9

chr4_-_186733363 0.127 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr5_-_138842286 0.126 ENST00000515823.1
ECSCR
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr21_-_46340807 0.125 ENST00000397846.3
ENST00000524251.1
ENST00000522688.1
ITGB2


integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)


chr16_+_66442411 0.125 ENST00000499966.1
LINC00920
long intergenic non-protein coding RNA 920
chr9_+_74920408 0.125 ENST00000451152.1
RP11-63P12.6
RP11-63P12.6
chr1_+_120049809 0.125 ENST00000531340.1
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr15_+_74833518 0.124 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr7_-_38389573 0.124 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr21_+_26934165 0.123 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr5_-_151066514 0.123 ENST00000538026.1
ENST00000522348.1
ENST00000521569.1
SPARC


secreted protein, acidic, cysteine-rich (osteonectin)


chr13_+_107029084 0.123 ENST00000444865.1
LINC00460
long intergenic non-protein coding RNA 460
chr12_+_76653611 0.122 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr7_-_143991230 0.121 ENST00000543357.1
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr5_+_20616500 0.120 ENST00000512688.1
RP11-774D14.1
RP11-774D14.1
chr1_-_150738261 0.119 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr10_-_24770632 0.116 ENST00000596413.1
AL353583.1
AL353583.1
chr11_+_63974135 0.116 ENST00000544997.1
ENST00000345728.5
ENST00000279227.5
FERMT3


fermitin family member 3


chr6_+_31553901 0.115 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1



leukocyte specific transcript 1



chr20_+_44746885 0.115 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr16_+_20817953 0.114 ENST00000568647.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr14_+_100204027 0.112 ENST00000554479.1
ENST00000555145.1
EML1

echinoderm microtubule associated protein like 1

chr2_-_75788038 0.112 ENST00000393913.3
ENST00000410113.1
EVA1A

eva-1 homolog A (C. elegans)

chr12_-_18243075 0.111 ENST00000536890.1
RERGL
RERG/RAS-like
chr16_+_66638003 0.110 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3





CKLF-like MARVEL transmembrane domain containing 3





chr3_-_128880125 0.110 ENST00000393295.3
ISY1
ISY1 splicing factor homolog (S. cerevisiae)
chr3_+_46742823 0.110 ENST00000326431.3
TMIE
transmembrane inner ear
chr8_+_143761874 0.110 ENST00000301258.4
ENST00000513264.1
PSCA

prostate stem cell antigen

chr5_+_82767284 0.110 ENST00000265077.3
VCAN
versican
chr2_+_3642545 0.108 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11


collectin sub-family member 11


chr12_+_110172572 0.108 ENST00000358906.3
FAM222A
family with sequence similarity 222, member A
chr12_-_18243119 0.107 ENST00000538724.1
ENST00000229002.2
RERGL

RERG/RAS-like

chr3_+_142720366 0.107 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP



U2 snRNP-associated SURP domain containing



chr21_+_38593701 0.107 ENST00000440629.1
AP001432.14
AP001432.14
chr9_-_4679419 0.107 ENST00000609131.1
ENST00000607997.1
RP11-6J24.6

RP11-6J24.6

chr13_+_47127322 0.106 ENST00000389798.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr2_-_75788428 0.106 ENST00000432649.1
EVA1A
eva-1 homolog A (C. elegans)
chr12_+_54422142 0.106 ENST00000243108.4
HOXC6
homeobox C6
chr3_+_119013185 0.106 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr17_-_61776522 0.106 ENST00000582055.1
LIMD2
LIM domain containing 2
chr16_+_66637777 0.105 ENST00000563672.1
ENST00000424011.2
CMTM3

CKLF-like MARVEL transmembrane domain containing 3

chr11_+_7618413 0.105 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_+_38673270 0.104 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr2_-_75788424 0.104 ENST00000410071.1
EVA1A
eva-1 homolog A (C. elegans)
chr10_+_15085918 0.104 ENST00000378225.1
OLAH
oleoyl-ACP hydrolase
chr3_-_179691866 0.103 ENST00000464614.1
ENST00000476138.1
ENST00000463761.1
PEX5L


peroxisomal biogenesis factor 5-like


chr2_-_99870744 0.103 ENST00000409238.1
ENST00000423800.1
LYG2

lysozyme G-like 2

chr12_-_57873631 0.102 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
ARHGAP9


Rho GTPase activating protein 9


chr6_-_119031228 0.102 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L


centrosomal protein 85kDa-like


chr15_+_40643227 0.101 ENST00000448599.2
PHGR1
proline/histidine/glycine-rich 1
chr12_+_9067123 0.101 ENST00000543824.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr3_+_134204551 0.101 ENST00000332047.5
ENST00000354446.3
CEP63

centrosomal protein 63kDa

chr12_+_9102632 0.101 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr7_+_144052381 0.100 ENST00000498580.1
ENST00000056217.5
ARHGEF5

Rho guanine nucleotide exchange factor (GEF) 5

chr12_-_57871853 0.100 ENST00000549602.1
ENST00000430041.2
ARHGAP9

Rho GTPase activating protein 9

chr17_-_61777090 0.099 ENST00000578061.1
LIMD2
LIM domain containing 2
chr16_+_20817761 0.099 ENST00000568046.1
ENST00000261377.6
AC004381.6

Putative RNA exonuclease NEF-sp

chr15_-_42186248 0.099 ENST00000320955.6
SPTBN5
spectrin, beta, non-erythrocytic 5
chr13_+_47127395 0.099 ENST00000389797.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr17_+_1959369 0.098 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr22_+_24105394 0.098 ENST00000305199.5
ENST00000382821.3
C22orf15

chromosome 22 open reading frame 15

chr1_-_152196669 0.097 ENST00000368801.2
HRNR
hornerin
chr16_+_29127282 0.097 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr7_+_134551583 0.096 ENST00000435928.1
CALD1
caldesmon 1
chr3_-_131221771 0.096 ENST00000510154.1
ENST00000507669.1
MRPL3

mitochondrial ribosomal protein L3

chr13_+_47127293 0.096 ENST00000311191.6
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr6_-_32191834 0.096 ENST00000375023.3
NOTCH4
notch 4
chr6_-_166755995 0.095 ENST00000361731.3
SFT2D1
SFT2 domain containing 1
chr12_-_58159361 0.095 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr21_-_46340770 0.095 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_-_238322770 0.093 ENST00000472056.1
COL6A3
collagen, type VI, alpha 3
chr22_-_37545972 0.093 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr11_-_3147835 0.092 ENST00000525498.1
OSBPL5
oxysterol binding protein-like 5
chr4_-_186732892 0.091 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chr3_+_132316081 0.091 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr21_-_46340884 0.091 ENST00000302347.5
ENST00000517819.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr1_+_116519223 0.090 ENST00000369502.1
SLC22A15
solute carrier family 22, member 15
chr1_-_162381907 0.090 ENST00000367929.2
ENST00000359567.3
SH2D1B

SH2 domain containing 1B

chr20_+_35201993 0.089 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr12_+_48147699 0.089 ENST00000548498.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr4_+_169575875 0.089 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr2_-_238322800 0.089 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr6_+_41606176 0.088 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI




MyoD family inhibitor




chr8_-_7274385 0.088 ENST00000318157.2
DEFB4B
defensin, beta 4B
chr13_-_33760216 0.087 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_57873329 0.087 ENST00000424809.2
ARHGAP9
Rho GTPase activating protein 9
chr11_+_60699222 0.087 ENST00000536409.1
TMEM132A
transmembrane protein 132A
chr2_+_127066059 0.086 ENST00000435352.1
AC023347.1
AC023347.1
chr15_+_39542867 0.085 ENST00000318578.3
ENST00000561223.1
C15orf54

chromosome 15 open reading frame 54

chr17_-_47865948 0.085 ENST00000513602.1
FAM117A
family with sequence similarity 117, member A
chr12_-_108733078 0.085 ENST00000552995.1
ENST00000312143.7
ENST00000397688.2
ENST00000550402.1
CMKLR1



chemokine-like receptor 1



chr2_-_238323007 0.085 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr9_+_74920335 0.085 ENST00000451596.2
ENST00000436054.1
RP11-63P12.6

RP11-63P12.6

chrX_-_8769378 0.084 ENST00000543214.1
ENST00000381003.3
FAM9A

family with sequence similarity 9, member A

chr12_-_57871825 0.084 ENST00000548139.1
ARHGAP9
Rho GTPase activating protein 9
chr1_+_206643806 0.084 ENST00000537984.1
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr11_-_26743546 0.084 ENST00000280467.6
ENST00000396005.3
SLC5A12

solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12

chr3_+_134204881 0.083 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
CEP63


centrosomal protein 63kDa


chr3_+_134205000 0.083 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
CEP63


centrosomal protein 63kDa


chr15_+_83776324 0.083 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1



transmembrane 6 superfamily member 1



chr4_+_2814011 0.083 ENST00000502260.1
ENST00000435136.2
SH3BP2

SH3-domain binding protein 2

chr16_-_67597789 0.082 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr21_+_44073860 0.081 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
PDE9A











phosphodiesterase 9A











chr20_-_23066953 0.081 ENST00000246006.4
CD93
CD93 molecule
chr11_+_36397731 0.081 ENST00000524380.1
PRR5L
proline rich 5 like
chr7_-_111428957 0.080 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chr1_-_31230650 0.079 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr6_-_130031358 0.079 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr19_-_46580352 0.079 ENST00000601672.1
IGFL4
IGF-like family member 4
chr5_+_173930710 0.079 ENST00000511707.1
RP11-267A15.1
RP11-267A15.1
chr11_+_118175596 0.079 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr10_+_129785536 0.078 ENST00000419012.2
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_+_206643787 0.078 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr6_+_144164455 0.078 ENST00000367576.5
LTV1
LTV1 homolog (S. cerevisiae)
chr3_+_29323043 0.078 ENST00000452462.1
ENST00000456853.1
RBMS3

RNA binding motif, single stranded interacting protein 3

chr11_+_12108410 0.078 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr1_-_167059830 0.077 ENST00000367868.3
GPA33
glycoprotein A33 (transmembrane)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.9 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 0.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.0 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.3 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.2 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 0.1 GO:1901079 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.6 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.0 GO:1903774 regulation of viral budding via host ESCRT complex(GO:1903772) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.0 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.0 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.0 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.0 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.0 GO:0051462 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.0 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.0 GO:0036090 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0072563 endothelial microparticle(GO:0072563)
0.2 0.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.3 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.0 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.0 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.5 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.1 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.0 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.0 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.0 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.1 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 3.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains