Motif ID: FIGLA

Z-value: 0.502


Transcription factors associated with FIGLA:

Gene SymbolEntrez IDGene Name
FIGLA ENSG00000183733.6 FIGLA



Activity profile for motif FIGLA.

activity profile for motif FIGLA


Sorted Z-values histogram for motif FIGLA

Sorted Z-values for motif FIGLA



Network of associatons between targets according to the STRING database.



First level regulatory network of FIGLA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_39258461 1.139 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chrX_-_137793826 1.047 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr5_-_54281491 1.015 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr5_-_54281407 0.989 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr19_+_36347787 0.483 ENST00000347900.6
ENST00000360202.5
KIRREL2

kin of IRRE like 2 (Drosophila)

chr17_+_9548845 0.457 ENST00000570475.1
ENST00000285199.7
USP43

ubiquitin specific peptidase 43

chr1_-_24438664 0.436 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
MYOM3


myomesin 3


chr17_+_12693001 0.436 ENST00000262444.9
ARHGAP44
Rho GTPase activating protein 44
chr17_+_39261584 0.420 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr4_-_6202247 0.365 ENST00000409021.3
ENST00000409371.3
JAKMIP1

janus kinase and microtubule interacting protein 1

chr22_-_37882395 0.327 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG


MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase


chr7_+_128784712 0.320 ENST00000289407.4
TSPAN33
tetraspanin 33
chr17_-_31204124 0.316 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
MYO1D


myosin ID


chr2_-_227050079 0.315 ENST00000423838.1
AC068138.1
AC068138.1
chr7_-_44122063 0.304 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM




polymerase (DNA directed), mu




chr22_+_22988816 0.298 ENST00000480559.1
ENST00000448514.1
GGTLC2

gamma-glutamyltransferase light chain 2

chr12_+_122150646 0.291 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr3_-_69435224 0.279 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr6_-_31550192 0.275 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr3_-_46904946 0.273 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr11_-_33913708 0.264 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_-_62586543 0.259 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_+_7618413 0.256 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_75788038 0.254 ENST00000393913.3
ENST00000410113.1
EVA1A

eva-1 homolog A (C. elegans)

chr17_-_39211463 0.253 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr6_+_12717892 0.241 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr14_+_69726656 0.239 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr1_-_40367668 0.227 ENST00000397332.2
ENST00000429311.1
MYCL

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

chr15_+_59730348 0.224 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A



family with sequence similarity 81, member A



chr3_-_46904918 0.223 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_+_155051305 0.220 ENST00000368408.3
EFNA3
ephrin-A3
chr14_+_69726864 0.215 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr7_-_27196267 0.206 ENST00000242159.3
HOXA7
homeobox A7
chr19_-_3786253 0.205 ENST00000585778.1
MATK
megakaryocyte-associated tyrosine kinase
chr11_+_120110863 0.204 ENST00000543440.2
POU2F3
POU class 2 homeobox 3
chr8_-_49833978 0.204 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_-_55352834 0.202 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr5_+_34656529 0.201 ENST00000513974.1
ENST00000512629.1
RAI14

retinoic acid induced 14

chr8_-_49834299 0.199 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr5_+_34656569 0.197 ENST00000428746.2
RAI14
retinoic acid induced 14
chr12_+_52450298 0.197 ENST00000550582.2
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr14_+_69726968 0.196 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chrX_-_33146477 0.191 ENST00000378677.2
DMD
dystrophin
chr11_+_86511549 0.189 ENST00000533902.2
PRSS23
protease, serine, 23
chr19_-_56056888 0.186 ENST00000592464.1
ENST00000420723.3
SBK3

SH3 domain binding kinase family, member 3

chr19_+_11658655 0.185 ENST00000588935.1
CNN1
calponin 1, basic, smooth muscle
chr14_+_75746664 0.184 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr17_+_45286387 0.177 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4



myosin, light chain 4, alkali; atrial, embryonic



chr19_-_56048456 0.175 ENST00000413299.1
SBK2
SH3 domain binding kinase family, member 2
chr1_-_40367530 0.164 ENST00000372816.2
ENST00000372815.1
MYCL

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

chr19_-_50316517 0.160 ENST00000313777.4
ENST00000445575.2
FUZ

fuzzy planar cell polarity protein

chr17_-_39254391 0.160 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr12_-_121972556 0.159 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr4_-_186456652 0.153 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr1_+_110754094 0.145 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4


potassium voltage-gated channel, Shaw-related subfamily, member 4


chr19_-_50316423 0.145 ENST00000528094.1
ENST00000526575.1
FUZ

fuzzy planar cell polarity protein

chr19_-_50316489 0.144 ENST00000533418.1
FUZ
fuzzy planar cell polarity protein
chr17_-_39216344 0.142 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr1_-_40782938 0.141 ENST00000372736.3
ENST00000372748.3
COL9A2

collagen, type IX, alpha 2

chr4_-_186456766 0.141 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr17_+_39421591 0.138 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr3_-_50383096 0.137 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr11_-_117698787 0.136 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr19_-_56047661 0.136 ENST00000344158.3
SBK2
SH3 domain binding kinase family, member 2
chr16_-_2260834 0.136 ENST00000562360.1
ENST00000566018.1
BRICD5

BRICHOS domain containing 5

chr12_+_19282643 0.136 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5





pleckstrin homology domain containing, family A member 5





chr6_-_39399087 0.133 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6


kinesin family member 6


chr1_+_155146318 0.129 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46





tripartite motif containing 46





chr16_+_88704978 0.129 ENST00000244241.4
IL17C
interleukin 17C
chr16_-_103572 0.128 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr17_-_40833858 0.127 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr14_-_58332774 0.121 ENST00000556826.1
SLC35F4
solute carrier family 35, member F4
chr12_+_79258547 0.119 ENST00000457153.2
SYT1
synaptotagmin I
chr6_-_130536774 0.117 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr5_+_72509751 0.117 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1


RP11-60A8.1


chr15_+_67547113 0.117 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH


IQ motif containing H


chr6_+_33172407 0.117 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr17_-_71088797 0.115 ENST00000580557.1
ENST00000579732.1
ENST00000578620.1
ENST00000542342.2
ENST00000255559.3
ENST00000579018.1
SLC39A11





solute carrier family 39, member 11





chr3_+_111393659 0.114 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr20_+_30407105 0.114 ENST00000375994.2
MYLK2
myosin light chain kinase 2
chr2_-_73340146 0.114 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chrX_-_11445856 0.112 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr12_+_79258444 0.111 ENST00000261205.4
SYT1
synaptotagmin I
chr14_-_37051798 0.111 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr15_+_67547163 0.111 ENST00000335894.4
IQCH
IQ motif containing H
chr20_+_30407151 0.110 ENST00000375985.4
MYLK2
myosin light chain kinase 2
chr3_-_49851313 0.110 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr15_+_91411810 0.110 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_-_48594248 0.109 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4





6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4





chr10_-_30637906 0.106 ENST00000417581.1
MTPAP
mitochondrial poly(A) polymerase
chr8_-_99837856 0.105 ENST00000518165.1
ENST00000419617.2
STK3

serine/threonine kinase 3

chr17_-_7165662 0.105 ENST00000571881.2
ENST00000360325.7
CLDN7

claudin 7

chr17_-_39296739 0.101 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr16_-_4465886 0.099 ENST00000539968.1
CORO7
coronin 7
chr10_-_30638090 0.099 ENST00000421701.1
ENST00000263063.4
MTPAP

mitochondrial poly(A) polymerase

chr19_-_42573650 0.098 ENST00000593562.1
GRIK5
glutamate receptor, ionotropic, kainate 5
chr15_+_68115895 0.098 ENST00000554240.1
SKOR1
SKI family transcriptional corepressor 1
chr6_+_44184653 0.097 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5

RP1-302G2.5

chr5_+_34656450 0.094 ENST00000514527.1
RAI14
retinoic acid induced 14
chrX_-_118827333 0.093 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6





septin 6





chr13_+_28194873 0.092 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr6_+_155537771 0.091 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr15_-_67546963 0.091 ENST00000561452.1
ENST00000261880.5
AAGAB

alpha- and gamma-adaptin binding protein

chr13_+_41635617 0.091 ENST00000542082.1
WBP4
WW domain binding protein 4
chr16_-_46864955 0.091 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr15_+_81299370 0.090 ENST00000560091.1
C15orf26
chromosome 15 open reading frame 26
chr3_-_16554881 0.088 ENST00000451036.1
RFTN1
raftlin, lipid raft linker 1
chr1_+_45478568 0.087 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chr3_+_111393501 0.086 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_+_35721106 0.086 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21



cAMP-regulated phosphoprotein, 21kDa



chr19_-_49118067 0.085 ENST00000593772.1
FAM83E
family with sequence similarity 83, member E
chr7_+_35756066 0.085 ENST00000449644.1
AC018647.3
AC018647.3
chr15_-_32162833 0.084 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr17_-_39203519 0.084 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr20_+_44441304 0.083 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr17_+_40985407 0.083 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3








proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)








chr20_+_44441215 0.083 ENST00000356455.4
ENST00000405520.1
UBE2C

ubiquitin-conjugating enzyme E2C

chr19_-_56109119 0.081 ENST00000587678.1
FIZ1
FLT3-interacting zinc finger 1
chr2_-_27603582 0.081 ENST00000323703.6
ENST00000436006.1
ZNF513

zinc finger protein 513

chr12_+_58176525 0.081 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM







Ts translation elongation factor, mitochondrial







chr15_-_45694380 0.081 ENST00000561148.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr1_-_55266865 0.080 ENST00000371274.4
TTC22
tetratricopeptide repeat domain 22
chr17_-_46657473 0.080 ENST00000332503.5
HOXB4
homeobox B4
chr16_-_30006922 0.079 ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chr15_-_75165651 0.078 ENST00000562363.1
ENST00000564529.1
ENST00000268099.9
SCAMP2


secretory carrier membrane protein 2


chr13_+_26828275 0.078 ENST00000381527.3
CDK8
cyclin-dependent kinase 8
chr2_-_220436248 0.078 ENST00000265318.4
OBSL1
obscurin-like 1
chr4_-_108204846 0.078 ENST00000513208.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr1_-_39339777 0.078 ENST00000397572.2
MYCBP
MYC binding protein
chr4_-_186125077 0.077 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430


KIAA1430


chr12_+_54674482 0.077 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
HNRNPA1




heterogeneous nuclear ribonucleoprotein A1




chr10_-_124768300 0.077 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr16_+_30006615 0.076 ENST00000563197.1
INO80E
INO80 complex subunit E
chr5_+_34656331 0.076 ENST00000265109.3
RAI14
retinoic acid induced 14
chr17_-_39222131 0.076 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr20_-_52645231 0.076 ENST00000448484.1
BCAS1
breast carcinoma amplified sequence 1
chr12_+_50017327 0.075 ENST00000261897.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr5_+_52856456 0.075 ENST00000296684.5
ENST00000506765.1
NDUFS4

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

chr3_-_49066811 0.074 ENST00000442157.1
ENST00000326739.4
IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

chr13_+_115000556 0.074 ENST00000252458.6
CDC16
cell division cycle 16
chr16_+_67233412 0.074 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr8_-_103425047 0.073 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr16_-_2162831 0.073 ENST00000483024.1
PKD1
polycystic kidney disease 1 (autosomal dominant)
chr12_-_49523896 0.073 ENST00000549870.1
TUBA1B
tubulin, alpha 1b
chr13_+_115000339 0.072 ENST00000360383.3
ENST00000375312.3
CDC16

cell division cycle 16

chrX_+_13587712 0.071 ENST00000361306.1
ENST00000380602.3
EGFL6

EGF-like-domain, multiple 6

chr7_-_99698338 0.071 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr10_+_94608218 0.070 ENST00000371543.1
EXOC6
exocyst complex component 6
chr9_+_33795533 0.070 ENST00000379405.3
PRSS3
protease, serine, 3
chr16_-_46865286 0.070 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr1_-_219615984 0.066 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr16_-_2314222 0.066 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr10_-_69991865 0.066 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr11_-_117698765 0.066 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr4_-_54457783 0.065 ENST00000263925.7
ENST00000512247.1
LNX1

ligand of numb-protein X 1, E3 ubiquitin protein ligase

chr7_+_2687173 0.065 ENST00000403167.1
TTYH3
tweety family member 3
chr14_-_20923195 0.065 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr10_+_94608245 0.065 ENST00000443748.2
ENST00000260762.6
EXOC6

exocyst complex component 6

chr19_+_14017003 0.064 ENST00000318003.7
CC2D1A
coiled-coil and C2 domain containing 1A
chr11_-_88070920 0.063 ENST00000524463.1
ENST00000227266.5
CTSC

cathepsin C

chr7_-_8301682 0.063 ENST00000396675.3
ENST00000430867.1
ICA1

islet cell autoantigen 1, 69kDa

chr4_+_15376165 0.063 ENST00000382383.3
ENST00000429690.1
C1QTNF7

C1q and tumor necrosis factor related protein 7

chr7_-_150675372 0.063 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_+_36238237 0.062 ENST00000457797.1
ENST00000394571.2
PNPLA1

patatin-like phospholipase domain containing 1

chr14_-_55369525 0.062 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1



GTP cyclohydrolase 1



chr19_+_55996565 0.062 ENST00000587400.1
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr8_-_103424986 0.062 ENST00000521922.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr4_-_140223670 0.062 ENST00000394228.1
ENST00000539387.1
NDUFC1

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

chrX_-_6146876 0.062 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr7_+_18535786 0.061 ENST00000406072.1
HDAC9
histone deacetylase 9
chr7_-_8301768 0.061 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr7_+_35756400 0.061 ENST00000585952.1
AC018647.3
AC018647.3
chr10_+_104614008 0.061 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chr2_+_173600514 0.061 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_-_103424916 0.061 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr11_+_93754513 0.061 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr2_-_178937478 0.060 ENST00000286063.6
PDE11A
phosphodiesterase 11A
chr17_-_4458616 0.060 ENST00000381556.2
MYBBP1A
MYB binding protein (P160) 1a
chr5_-_1295104 0.060 ENST00000334602.6
ENST00000508104.2
ENST00000310581.5
ENST00000296820.5
TERT



telomerase reverse transcriptase



chr11_-_118972575 0.060 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr7_+_18535893 0.060 ENST00000432645.2
ENST00000441542.2
HDAC9

histone deacetylase 9

chr10_+_104613980 0.059 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32
chr16_+_103816 0.059 ENST00000383018.3
ENST00000417493.1
SNRNP25

small nuclear ribonucleoprotein 25kDa (U11/U12)

chr1_+_100316041 0.059 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
AGL


amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase


chr1_-_171621815 0.059 ENST00000037502.6
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr8_-_102216925 0.058 ENST00000517844.1
ZNF706
zinc finger protein 706
chr12_-_75603236 0.058 ENST00000540018.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr5_-_158636512 0.057 ENST00000424310.2
RNF145
ring finger protein 145
chr1_+_100315613 0.056 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr3_+_68055366 0.056 ENST00000496687.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr12_-_75603482 0.056 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2


potassium voltage-gated channel, Shaw-related subfamily, member 2


chr19_+_16187085 0.055 ENST00000300933.4
TPM4
tropomyosin 4
chr7_-_8302164 0.055 ENST00000447326.1
ENST00000406470.2
ICA1

islet cell autoantigen 1, 69kDa

chr16_+_2286726 0.055 ENST00000382437.4
ENST00000569184.1
DNASE1L2

deoxyribonuclease I-like 2

chr6_-_114292449 0.054 ENST00000519065.1
HDAC2
histone deacetylase 2
chr16_+_77224732 0.054 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1B





MON1 secretory trafficking family member B





chr11_-_65629497 0.054 ENST00000532134.1
CFL1
cofilin 1 (non-muscle)
chr7_+_18535854 0.053 ENST00000401921.1
HDAC9
histone deacetylase 9
chr17_-_39183452 0.052 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr7_+_20370746 0.052 ENST00000222573.4
ITGB8
integrin, beta 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2 1.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.4 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.4 GO:0050890 cognition(GO:0050890)
0.0 0.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.3 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.0 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.7 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction