Motif ID: EN1_ESX1_GBX1

Z-value: 0.379

Transcription factors associated with EN1_ESX1_GBX1:

Gene SymbolEntrez IDGene Name
EN1 ENSG00000163064.6 EN1
ESX1 ENSG00000123576.5 ESX1
GBX1 ENSG00000164900.4 GBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ESX1hg19_v2_chrX_-_103499602_1034996170.117.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169013666 0.512 ENST00000359299.3
ANXA10
annexin A10
chr12_+_52695617 0.311 ENST00000293525.5
KRT86
keratin 86
chr10_+_5005598 0.255 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr4_-_36245561 0.231 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_158114051 0.183 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr19_+_4153598 0.181 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3




cAMP responsive element binding protein 3-like 3




chr3_+_173116225 0.173 ENST00000457714.1
NLGN1
neuroligin 1
chrX_+_105192423 0.161 ENST00000540278.1
NRK
Nik related kinase
chr12_-_10022735 0.160 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr8_+_92261516 0.158 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr2_+_65216462 0.157 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr10_-_56561022 0.151 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
PCDH15













protocadherin-related 15













chr4_-_105416039 0.141 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr17_-_39150385 0.138 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr11_+_34663913 0.136 ENST00000532302.1
EHF
ets homologous factor
chr4_-_25865159 0.136 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr8_-_42234745 0.136 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr10_-_5046042 0.135 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr14_+_39944025 0.134 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr4_-_46911248 0.132 ENST00000355591.3
ENST00000505102.1
COX7B2

cytochrome c oxidase subunit VIIb2

chr15_+_94899183 0.128 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr18_+_32173276 0.122 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chrX_-_106243451 0.121 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr11_-_16419067 0.117 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr11_+_34664014 0.116 ENST00000527935.1
EHF
ets homologous factor
chrX_+_77166172 0.116 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chrX_-_106243294 0.115 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr12_-_16760021 0.114 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_-_22498950 0.114 ENST00000422359.2
EBLN1
endogenous Bornavirus-like nucleoprotein 1
chr4_-_74486217 0.109 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr12_+_16500599 0.108 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1



microsomal glutathione S-transferase 1



chr4_-_74486109 0.108 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chrX_+_107288280 0.106 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr12_+_16500037 0.100 ENST00000536371.1
ENST00000010404.2
MGST1

microsomal glutathione S-transferase 1

chr3_-_178984759 0.100 ENST00000349697.2
ENST00000497599.1
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr12_+_16500571 0.099 ENST00000543076.1
ENST00000396210.3
MGST1

microsomal glutathione S-transferase 1

chr18_+_32402321 0.099 ENST00000587723.1
DTNA
dystrobrevin, alpha
chr8_+_32579321 0.098 ENST00000522402.1
NRG1
neuregulin 1
chr1_+_62439037 0.097 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_-_232651312 0.096 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_+_147145709 0.096 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr4_-_46911223 0.095 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr8_+_32579341 0.095 ENST00000519240.1
ENST00000539990.1
NRG1

neuregulin 1

chr8_-_19614810 0.094 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr19_-_51522955 0.094 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chrX_-_13835147 0.094 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr1_+_28261533 0.094 ENST00000411604.1
ENST00000373888.4
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr8_+_32579271 0.094 ENST00000518084.1
NRG1
neuregulin 1
chr17_-_40337470 0.087 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr14_+_32798547 0.084 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr2_-_145188137 0.084 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr10_-_50970382 0.084 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr1_+_81771806 0.084 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr2_-_190446738 0.083 ENST00000427419.1
ENST00000455320.1
SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

chr9_+_12693336 0.083 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr10_-_56560939 0.082 ENST00000373955.1
PCDH15
protocadherin-related 15
chr12_-_10007448 0.081 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr9_+_136501478 0.079 ENST00000393056.2
ENST00000263611.2
DBH

dopamine beta-hydroxylase (dopamine beta-monooxygenase)

chr1_+_160160346 0.079 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr12_-_16759440 0.078 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_53171128 0.078 ENST00000332411.2
KRT76
keratin 76
chr18_+_13465008 0.077 ENST00000593236.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr2_-_145277569 0.076 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr7_-_14029283 0.075 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr20_-_50418972 0.074 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr1_+_160160283 0.074 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_-_167191814 0.073 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr8_-_86290333 0.073 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1










carbonic anhydrase I










chr1_+_244515930 0.071 ENST00000366537.1
ENST00000308105.4
C1orf100

chromosome 1 open reading frame 100

chr4_-_74486347 0.070 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_-_77427676 0.070 ENST00000257663.3
TMEM60
transmembrane protein 60
chr10_-_92681033 0.069 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr11_-_124981475 0.069 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218











transmembrane protein 218











chr12_-_28122980 0.069 ENST00000395868.3
ENST00000534890.1
PTHLH

parathyroid hormone-like hormone

chr1_-_190446759 0.068 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr12_-_28123206 0.068 ENST00000542963.1
ENST00000535992.1
PTHLH

parathyroid hormone-like hormone

chr7_-_92777606 0.068 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr10_-_50970322 0.067 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr7_-_121944491 0.067 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr4_+_66536248 0.066 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr11_+_34654011 0.066 ENST00000531794.1
EHF
ets homologous factor
chr9_+_12695702 0.065 ENST00000381136.2
TYRP1
tyrosinase-related protein 1
chr8_+_98900132 0.063 ENST00000520016.1
MATN2
matrilin 2
chr12_+_56473939 0.063 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_-_159832438 0.062 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr6_-_32157947 0.062 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr1_-_22215192 0.062 ENST00000374673.3
HSPG2
heparan sulfate proteoglycan 2
chr5_-_141249154 0.062 ENST00000357517.5
ENST00000536585.1
PCDH1

protocadherin 1

chr20_-_35890211 0.062 ENST00000373614.2
GHRH
growth hormone releasing hormone
chr7_+_100136811 0.061 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chr3_-_55521323 0.061 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr12_-_10605929 0.061 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr3_-_180397256 0.060 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr4_+_77356248 0.059 ENST00000296043.6
SHROOM3
shroom family member 3
chr11_+_35222629 0.059 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr14_-_54423529 0.058 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr11_-_58207646 0.057 ENST00000302572.2
OR5B12
olfactory receptor, family 5, subfamily B, member 12
chr8_-_7243080 0.057 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr2_+_169926047 0.057 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr1_+_196788887 0.057 ENST00000367421.3
ENST00000320493.5
ENST00000367424.4
CFHR2
CFHR1

complement factor H-related 2
complement factor H-related 1

chr5_-_115890554 0.056 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_+_31193847 0.056 ENST00000514738.1
ENST00000265071.2
CDH6

cadherin 6, type 2, K-cadherin (fetal kidney)

chr6_+_26020672 0.054 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr3_+_167453493 0.053 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr13_-_67802549 0.052 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr19_-_14064114 0.052 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1



podocan-like 1



chr4_-_109541610 0.052 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr8_+_98881268 0.052 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2


matrilin 2


chrX_+_107334895 0.052 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A


autophagy related 4A, cysteine peptidase


chr11_-_40315640 0.052 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr15_+_59910132 0.050 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chrX_-_153602991 0.049 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr7_+_6655225 0.049 ENST00000457543.3
ZNF853
zinc finger protein 853
chr17_+_47448102 0.049 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr15_+_51669513 0.048 ENST00000558426.1
GLDN
gliomedin
chr2_-_188419078 0.047 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr17_+_61151306 0.047 ENST00000580068.1
ENST00000580466.1
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr17_+_62223320 0.047 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr5_+_125758865 0.046 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chrX_+_107334983 0.046 ENST00000457035.1
ENST00000545696.1
ATG4A

autophagy related 4A, cysteine peptidase

chr7_-_87342564 0.045 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr5_+_109218883 0.045 ENST00000523446.1
AC011366.3
Uncharacterized protein
chr5_+_125758813 0.045 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr14_-_21994337 0.044 ENST00000537235.1
ENST00000450879.2
SALL2

spalt-like transcription factor 2

chr10_-_21186144 0.044 ENST00000377119.1
NEBL
nebulette
chr3_+_179322481 0.044 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr3_+_152552685 0.044 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr6_-_26032288 0.043 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr8_-_18744528 0.043 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_57547870 0.043 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX



HOP homeobox



chr22_+_18632666 0.043 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr5_-_159827033 0.043 ENST00000523213.1
C5orf54
chromosome 5 open reading frame 54
chr7_+_73245193 0.043 ENST00000340958.2
CLDN4
claudin 4
chr1_+_209878182 0.042 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_+_125133315 0.042 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr12_-_94673956 0.042 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr4_-_89205350 0.042 ENST00000509340.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr6_+_39760129 0.042 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr12_+_104680659 0.042 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1





thioredoxin reductase 1





chr7_-_14029515 0.042 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1


ets variant 1


chr5_+_52776449 0.042 ENST00000396947.3
FST
follistatin
chr20_-_18447667 0.041 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1


double zinc ribbon and ankyrin repeat domains 1


chr12_+_7013897 0.041 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr9_+_116225999 0.041 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr5_+_176811431 0.041 ENST00000512593.1
ENST00000324417.5
SLC34A1

solute carrier family 34 (type II sodium/phosphate contransporter), member 1

chr8_+_9413410 0.040 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS


tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase


chr11_+_101918153 0.040 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr9_+_12775011 0.040 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr14_+_56584414 0.040 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr12_+_56473910 0.040 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr5_+_52776228 0.039 ENST00000256759.3
FST
follistatin
chr12_+_104680793 0.039 ENST00000529546.1
ENST00000529751.1
ENST00000540716.1
ENST00000528079.2
ENST00000526580.1
TXNRD1




thioredoxin reductase 1




chr14_-_52066633 0.039 ENST00000557625.1
FRMD6-AS2
FRMD6 antisense RNA 2
chr6_-_26199471 0.039 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr11_+_59824060 0.039 ENST00000395032.2
ENST00000358152.2
MS4A3

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)

chr2_-_176046391 0.039 ENST00000392541.3
ENST00000409194.1
ATP5G3

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)

chr15_-_53002007 0.039 ENST00000561490.1
FAM214A
family with sequence similarity 214, member A
chr22_-_28490123 0.038 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr4_+_95916947 0.038 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr2_+_143635067 0.038 ENST00000264170.4
KYNU
kynureninase
chr9_-_5304432 0.038 ENST00000416837.1
ENST00000308420.3
RLN2

relaxin 2

chr4_+_71587669 0.038 ENST00000381006.3
ENST00000226328.4
RUFY3

RUN and FYVE domain containing 3

chr5_-_140700322 0.037 ENST00000313368.5
TAF7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr1_+_28261492 0.037 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_28261621 0.037 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_-_21625486 0.036 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr11_+_118398178 0.035 ENST00000302783.4
ENST00000539546.1
TTC36

tetratricopeptide repeat domain 36

chr6_+_97753454 0.035 ENST00000574739.1
RP3-418C23.2
RP3-418C23.2
chr1_+_8021954 0.035 ENST00000377491.1
ENST00000377488.1
PARK7

parkinson protein 7

chr11_+_77532233 0.035 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr10_+_118083919 0.035 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr7_+_129984630 0.035 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chr1_+_10290822 0.035 ENST00000377083.1
KIF1B
kinesin family member 1B
chr10_+_24497704 0.034 ENST00000376456.4
ENST00000458595.1
KIAA1217

KIAA1217

chr7_-_14028488 0.034 ENST00000405358.4
ETV1
ets variant 1
chr6_-_116833500 0.034 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr1_+_222910625 0.034 ENST00000360827.2
FAM177B
family with sequence similarity 177, member B
chrX_+_72783026 0.034 ENST00000373504.6
ENST00000373502.5
CHIC1

cysteine-rich hydrophobic domain 1

chr1_-_10532531 0.034 ENST00000377036.2
ENST00000377038.3
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr1_-_8877692 0.034 ENST00000400908.2
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr1_+_214161272 0.034 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr5_+_125759140 0.033 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr14_+_39734482 0.033 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5



CTAGE family, member 5



chr20_+_18488137 0.033 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B



Sec23 homolog B (S. cerevisiae)



chr4_-_168155169 0.033 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chrX_+_22050546 0.033 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr4_+_150999418 0.033 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr18_+_44526744 0.033 ENST00000585469.1
KATNAL2
katanin p60 subunit A-like 2
chrX_+_100224676 0.032 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chrX_+_108779004 0.032 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr4_-_39979576 0.032 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr1_+_226013047 0.032 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr6_-_31830655 0.032 ENST00000375631.4
NEU1
sialidase 1 (lysosomal sialidase)
chr12_-_88974236 0.032 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG


KIT ligand


chr4_+_105828492 0.032 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr7_-_25019760 0.032 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chr5_-_132200477 0.031 ENST00000296875.2
GDF9
growth differentiation factor 9
chr5_+_150639360 0.031 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr6_+_26158343 0.030 ENST00000377777.4
ENST00000289316.2
HIST1H2BD

histone cluster 1, H2bd

chr14_+_32798462 0.030 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.4 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:0098942 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746) cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.0 0.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.0 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.1 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling