Motif ID: E2F6

Z-value: 0.564


Transcription factors associated with E2F6:

Gene SymbolEntrez IDGene Name
E2F6 ENSG00000169016.12 E2F6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2F6hg19_v2_chr2_-_11606275_11606289-0.781.3e-02Click!


Activity profile for motif E2F6.

activity profile for motif E2F6


Sorted Z-values histogram for motif E2F6

Sorted Z-values for motif E2F6



Network of associatons between targets according to the STRING database.



First level regulatory network of E2F6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_58005204 0.884 ENST00000286494.4
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chrX_-_137793826 0.717 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr12_+_54332535 0.666 ENST00000243056.3
HOXC13
homeobox C13
chr17_+_1959369 0.625 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr10_+_99609996 0.556 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr4_-_6202291 0.551 ENST00000282924.5
JAKMIP1
janus kinase and microtubule interacting protein 1
chr17_-_48207115 0.535 ENST00000511964.1
SAMD14
sterile alpha motif domain containing 14
chr1_-_48462566 0.527 ENST00000606738.2
TRABD2B
TraB domain containing 2B
chr6_+_12749657 0.519 ENST00000406205.2
PHACTR1
phosphatase and actin regulator 1
chr17_+_47287749 0.467 ENST00000419580.2
ABI3
ABI family, member 3
chrX_-_151619746 0.449 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr19_-_51222707 0.420 ENST00000391814.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr4_-_6202247 0.406 ENST00000409021.3
ENST00000409371.3
JAKMIP1

janus kinase and microtubule interacting protein 1

chr1_+_53793885 0.397 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr1_-_200992827 0.391 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr14_+_24867992 0.386 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr17_-_47287928 0.380 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr4_+_7194247 0.376 ENST00000507866.2
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr14_-_51561784 0.371 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr7_-_32111009 0.362 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
PDE1C


phosphodiesterase 1C, calmodulin-dependent 70kDa


chr13_-_96296944 0.361 ENST00000361396.2
ENST00000376829.2
DZIP1

DAZ interacting zinc finger protein 1

chr8_+_104513086 0.355 ENST00000406091.3
RIMS2
regulating synaptic membrane exocytosis 2
chr1_-_159832438 0.346 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr19_-_10628098 0.343 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr3_-_66551351 0.342 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr22_+_42229100 0.341 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr15_-_79103757 0.341 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr2_-_31361543 0.320 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr3_-_113415441 0.316 ENST00000491165.1
ENST00000316407.4
KIAA2018

KIAA2018

chr12_+_54410664 0.313 ENST00000303406.4
HOXC4
homeobox C4
chr2_-_31361362 0.306 ENST00000430167.1
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr2_+_128377550 0.302 ENST00000437387.1
ENST00000409090.1
MYO7B

myosin VIIB

chr4_-_111536534 0.302 ENST00000503456.1
ENST00000513690.1
RP11-380D23.2

RP11-380D23.2

chr19_+_48898132 0.300 ENST00000263269.3
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr10_-_62493223 0.298 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_-_10628117 0.296 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr7_-_41740181 0.295 ENST00000442711.1
INHBA
inhibin, beta A
chr20_+_45338126 0.293 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr12_+_57610562 0.292 ENST00000349394.5
NXPH4
neurexophilin 4
chr14_-_51562037 0.287 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr3_-_55515400 0.287 ENST00000497027.1
WNT5A
wingless-type MMTV integration site family, member 5A
chrX_-_138287168 0.282 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr16_+_56225248 0.281 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr13_-_36705425 0.279 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1


doublecortin-like kinase 1


chr6_+_12012536 0.278 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr15_-_60884706 0.276 ENST00000449337.2
RORA
RAR-related orphan receptor A
chr17_+_74864476 0.274 ENST00000301618.4
ENST00000569840.2
MGAT5B

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

chr12_+_6930813 0.273 ENST00000428545.2
GPR162
G protein-coupled receptor 162
chr20_+_61340179 0.267 ENST00000370501.3
NTSR1
neurotensin receptor 1 (high affinity)
chr16_-_77468945 0.266 ENST00000282849.5
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr7_-_45128472 0.264 ENST00000490531.2
NACAD
NAC alpha domain containing
chr2_-_73511407 0.262 ENST00000520530.2
FBXO41
F-box protein 41
chr7_-_559853 0.262 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr18_+_47088401 0.260 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr15_+_81293254 0.258 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr3_-_66551397 0.258 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr1_-_45672221 0.257 ENST00000359600.5
ZSWIM5
zinc finger, SWIM-type containing 5
chr19_+_36347787 0.256 ENST00000347900.6
ENST00000360202.5
KIRREL2

kin of IRRE like 2 (Drosophila)

chr4_+_54966198 0.254 ENST00000326902.2
ENST00000503800.1
GSX2

GS homeobox 2

chr5_+_176237478 0.248 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr14_-_25519095 0.247 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6



syntaxin binding protein 6 (amisyn)



chr1_-_166136187 0.244 ENST00000338353.3
FAM78B
family with sequence similarity 78, member B
chr11_-_65641044 0.244 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr1_+_117452669 0.242 ENST00000393203.2
PTGFRN
prostaglandin F2 receptor inhibitor
chr1_+_114522049 0.239 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chr14_+_21538517 0.236 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr2_-_72375167 0.235 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr13_+_98795434 0.232 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr15_+_54305101 0.231 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C


unc-13 homolog C (C. elegans)


chr8_+_37654693 0.231 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr3_-_17783990 0.230 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5







TBC1 domain family, member 5







chr12_+_6930964 0.230 ENST00000382315.3
GPR162
G protein-coupled receptor 162
chr13_+_98795505 0.229 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr15_+_65134088 0.227 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr17_-_42907564 0.224 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr11_-_133826852 0.224 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr16_+_66461175 0.223 ENST00000536005.2
ENST00000299694.8
ENST00000561796.1
BEAN1


brain expressed, associated with NEDD4, 1


chr1_-_50489547 0.222 ENST00000371836.1
ENST00000371839.1
ENST00000371838.1
AGBL4


ATP/GTP binding protein-like 4


chr1_+_213123862 0.220 ENST00000366966.2
ENST00000366964.3
VASH2

vasohibin 2

chr3_-_55515202 0.220 ENST00000482079.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr4_-_185570590 0.219 ENST00000517513.1
ENST00000447121.2
ENST00000393588.4
ENST00000308394.4
ENST00000523916.1
CASP3




caspase 3, apoptosis-related cysteine peptidase




chr3_+_54156664 0.219 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr12_+_49212514 0.218 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3


calcium channel, voltage-dependent, beta 3 subunit


chr2_-_70995307 0.215 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
ADD2




adducin 2 (beta)




chr2_-_74667612 0.215 ENST00000305557.5
ENST00000233330.6
RTKN

rhotekin

chr1_-_49242553 0.212 ENST00000371833.3
BEND5
BEN domain containing 5
chr14_-_25519317 0.209 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr19_-_48673465 0.209 ENST00000598938.1
LIG1
ligase I, DNA, ATP-dependent
chr3_+_5020801 0.205 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr19_+_51226573 0.205 ENST00000250340.4
CLEC11A
C-type lectin domain family 11, member A
chr17_-_56406117 0.203 ENST00000268893.6
ENST00000355701.3
BZRAP1

benzodiazepine receptor (peripheral) associated protein 1

chr5_+_135364584 0.203 ENST00000442011.2
ENST00000305126.8
TGFBI

transforming growth factor, beta-induced, 68kDa

chr14_+_21538429 0.202 ENST00000298694.4
ENST00000555038.1
ARHGEF40

Rho guanine nucleotide exchange factor (GEF) 40

chr18_+_43409037 0.202 ENST00000546268.1
SIGLEC15
sialic acid binding Ig-like lectin 15
chr17_-_31204124 0.201 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
MYO1D


myosin ID


chr3_-_133614297 0.201 ENST00000486858.1
ENST00000477759.1
RAB6B

RAB6B, member RAS oncogene family

chr4_+_183065793 0.195 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr2_-_218808771 0.194 ENST00000449814.1
ENST00000171887.4
TNS1

tensin 1

chr14_-_91526922 0.193 ENST00000418736.2
ENST00000261991.3
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr3_+_46924829 0.193 ENST00000313049.5
PTH1R
parathyroid hormone 1 receptor
chr2_+_63277927 0.192 ENST00000282549.2
OTX1
orthodenticle homeobox 1
chr22_-_39639021 0.191 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr19_-_48673552 0.190 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chr9_-_139094988 0.190 ENST00000371746.3
LHX3
LIM homeobox 3
chr17_-_44896047 0.189 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr12_+_49212261 0.189 ENST00000547818.1
ENST00000547392.1
CACNB3

calcium channel, voltage-dependent, beta 3 subunit

chr6_+_12012170 0.189 ENST00000487103.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr15_+_73344911 0.188 ENST00000560262.1
ENST00000558964.1
NEO1

neogenin 1

chr15_+_63340647 0.188 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr20_-_31071239 0.188 ENST00000359676.5
C20orf112
chromosome 20 open reading frame 112
chr19_-_11308190 0.187 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2




KN motif and ankyrin repeat domains 2




chr10_-_118031778 0.187 ENST00000369236.1
GFRA1
GDNF family receptor alpha 1
chr19_+_4229495 0.187 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr15_+_63340775 0.186 ENST00000559281.1
ENST00000317516.7
TPM1

tropomyosin 1 (alpha)

chr15_+_75074915 0.186 ENST00000567123.1
ENST00000569462.1
CSK

c-src tyrosine kinase

chr5_+_121647764 0.185 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
SNCAIP



synuclein, alpha interacting protein



chr14_+_65171099 0.184 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr14_+_94640633 0.184 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr15_-_86338134 0.181 ENST00000337975.5
KLHL25
kelch-like family member 25
chr12_+_54447637 0.181 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr13_+_28712614 0.181 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr20_+_6748311 0.180 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr14_+_65171315 0.180 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_+_55795493 0.180 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr15_-_86338100 0.180 ENST00000536947.1
KLHL25
kelch-like family member 25
chr15_+_75074410 0.179 ENST00000439220.2
CSK
c-src tyrosine kinase
chr2_+_71693812 0.179 ENST00000409651.1
ENST00000394120.2
ENST00000409744.1
ENST00000409366.1
ENST00000410020.3
ENST00000410041.1
DYSF





dysferlin





chr12_+_50451462 0.179 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr15_+_63340734 0.178 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr9_-_72287191 0.178 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr12_+_52445191 0.178 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr2_-_208030647 0.177 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr15_+_75074385 0.176 ENST00000220003.9
CSK
c-src tyrosine kinase
chr2_-_72374948 0.174 ENST00000546307.1
ENST00000474509.1
CYP26B1

cytochrome P450, family 26, subfamily B, polypeptide 1

chr15_+_63340553 0.174 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr14_-_38064198 0.173 ENST00000250448.2
FOXA1
forkhead box A1
chr3_-_46904946 0.173 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr15_-_82338460 0.172 ENST00000558133.1
ENST00000329713.4
MEX3B

mex-3 RNA binding family member B

chr22_+_45098067 0.172 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
PRR5


PRR5-ARHGAP8
proline rich 5 (renal)


PRR5-ARHGAP8 readthrough
chr12_+_50451331 0.171 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr19_-_48673580 0.171 ENST00000427526.2
LIG1
ligase I, DNA, ATP-dependent
chr1_+_213123976 0.170 ENST00000366965.2
ENST00000366967.2
VASH2

vasohibin 2

chr12_+_54384370 0.170 ENST00000504315.1
HOXC6
homeobox C6
chr3_-_71774516 0.168 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr19_-_3480540 0.168 ENST00000215531.4
C19orf77
chromosome 19 open reading frame 77
chr12_+_93964158 0.167 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr22_-_37882395 0.166 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG


MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase


chr12_+_6930703 0.166 ENST00000311268.3
GPR162
G protein-coupled receptor 162
chr20_+_61273797 0.166 ENST00000217159.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr4_+_62067860 0.166 ENST00000514591.1
LPHN3
latrophilin 3
chr2_-_64246206 0.164 ENST00000409558.4
ENST00000272322.4
VPS54

vacuolar protein sorting 54 homolog (S. cerevisiae)

chr1_-_54872059 0.163 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr15_-_78423567 0.162 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
CIB2



calcium and integrin binding family member 2



chr14_-_95786200 0.162 ENST00000298912.4
CLMN
calmin (calponin-like, transmembrane)
chr13_-_72441315 0.162 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1


dachshund homolog 1 (Drosophila)


chr13_-_50367057 0.162 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chrX_+_118370288 0.161 ENST00000535419.1
PGRMC1
progesterone receptor membrane component 1
chr2_-_85108363 0.161 ENST00000335459.5
TRABD2A
TraB domain containing 2A
chr17_+_6918064 0.160 ENST00000546760.1
ENST00000552402.1
C17orf49

chromosome 17 open reading frame 49

chr17_+_6918093 0.160 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr3_+_111717511 0.160 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr3_-_9595480 0.160 ENST00000287585.6
LHFPL4
lipoma HMGIC fusion partner-like 4
chr14_+_65170820 0.159 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_+_135229600 0.158 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr10_-_46313036 0.158 ENST00000411791.3
FAM25E
family with sequence similarity 25, member E
chr15_-_78423886 0.158 ENST00000258930.3
CIB2
calcium and integrin binding family member 2
chr15_-_72612470 0.157 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr3_+_54156570 0.157 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr15_-_75743915 0.157 ENST00000394949.4
SIN3A
SIN3 transcription regulator family member A
chr16_+_56260291 0.157 ENST00000563440.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr6_-_134495992 0.155 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1


serum/glucocorticoid regulated kinase 1


chr11_-_3186494 0.155 ENST00000389989.3
ENST00000542243.1
OSBPL5

oxysterol binding protein-like 5

chrX_+_68835911 0.155 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA





ectodysplasin A





chr14_+_96342729 0.154 ENST00000504119.1
LINC00617
long intergenic non-protein coding RNA 617
chr3_-_133614467 0.154 ENST00000469959.1
RAB6B
RAB6B, member RAS oncogene family
chr16_-_54963026 0.153 ENST00000560208.1
ENST00000557792.1
CRNDE

colorectal neoplasia differentially expressed (non-protein coding)

chr15_-_75744014 0.153 ENST00000394947.3
ENST00000565264.1
SIN3A

SIN3 transcription regulator family member A

chr19_+_49622646 0.152 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr2_-_85108164 0.152 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr1_+_213123915 0.152 ENST00000366968.4
ENST00000490792.1
VASH2

vasohibin 2

chr19_+_51226648 0.152 ENST00000599973.1
CLEC11A
C-type lectin domain family 11, member A
chr22_+_45064593 0.150 ENST00000432186.1
PRR5
proline rich 5 (renal)
chr14_+_21566980 0.149 ENST00000418511.2
ENST00000554329.2
TMEM253

transmembrane protein 253

chr17_+_65373531 0.148 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr20_+_42875887 0.148 ENST00000342560.5
GDAP1L1
ganglioside induced differentiation associated protein 1-like 1
chr2_+_172949468 0.147 ENST00000361609.4
ENST00000469444.2
DLX1

distal-less homeobox 1

chr17_+_7344057 0.145 ENST00000575398.1
ENST00000575082.1
FGF11

fibroblast growth factor 11

chr12_-_120554534 0.145 ENST00000538903.1
ENST00000534951.1
RAB35

RAB35, member RAS oncogene family

chr12_+_49209348 0.145 ENST00000536187.2
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr17_+_44039704 0.145 ENST00000420682.2
ENST00000415613.2
ENST00000571987.1
ENST00000574436.1
ENST00000431008.3
MAPT




microtubule-associated protein tau




chr16_+_28303804 0.144 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr12_+_9067123 0.144 ENST00000543824.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chrX_+_135229731 0.143 ENST00000420362.1
FHL1
four and a half LIM domains 1
chr2_+_71127699 0.142 ENST00000234392.2
VAX2
ventral anterior homeobox 2
chr11_-_74178582 0.142 ENST00000531854.1
ENST00000526855.1
ENST00000529425.1
ENST00000310128.4
ENST00000532569.1
KCNE3




potassium voltage-gated channel, Isk-related family, member 3




chr1_+_203096831 0.141 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr17_-_48207157 0.141 ENST00000330175.4
ENST00000503131.1
SAMD14

sterile alpha motif domain containing 14

chr10_-_79397391 0.140 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr12_-_121973974 0.140 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B


lysine (K)-specific demethylase 2B


chr8_+_118533049 0.140 ENST00000522839.1
MED30
mediator complex subunit 30

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.2 0.6 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.2 1.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.7 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.4 GO:0050894 determination of affect(GO:0050894)
0.1 0.4 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.5 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.3 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.3 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.4 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1 0.3 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 0.2 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.1 GO:0042472 inner ear morphogenesis(GO:0042472)
0.1 0.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.3 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.1 0.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.1 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.1 0.1 GO:0007569 cell aging(GO:0007569)
0.1 0.2 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.1 GO:0071283 cellular response to iron(III) ion(GO:0071283)
0.1 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.3 GO:1904970 brush border assembly(GO:1904970)
0.1 0.2 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.7 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.2 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.2 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.0 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.6 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.0 GO:0060066 oviduct development(GO:0060066)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:1901186 positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.2 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.6 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:2000625 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.0 GO:0097107 postsynaptic density assembly(GO:0097107)
0.0 0.3 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.0 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.0 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.0 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.1 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.0 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.0 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.0 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.1 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.0 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.0 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.0 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:0061205 alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0 0.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.1 GO:0000732 strand displacement(GO:0000732)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.0 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0048477 oogenesis(GO:0048477)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.4 GO:0050890 cognition(GO:0050890)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.0 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.0 GO:0060353 cell adhesion molecule production(GO:0060352) regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.3 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.2 GO:0075713 establishment of integrated proviral latency(GO:0075713)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.0 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.0 GO:0002692 negative regulation of cellular extravasation(GO:0002692)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.2 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.0 GO:0000806 Y chromosome(GO:0000806)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.0 GO:1902710 GABA receptor complex(GO:1902710)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.0 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 1.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.0 GO:0044301 climbing fiber(GO:0044301)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0036387 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.0 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0005726 perichromatin fibrils(GO:0005726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.5 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 0.5 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.7 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.5 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0030305 heparanase activity(GO:0030305)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.0 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0042979 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.0 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.4 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.4 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 1.5 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.0 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.5 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling