Motif ID: DUXA

Z-value: 0.719


Transcription factors associated with DUXA:

Gene SymbolEntrez IDGene Name
DUXA ENSG00000258873.2 DUXA

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DUXAhg19_v2_chr19_-_57678811_576788110.863.1e-03Click!


Activity profile for motif DUXA.

activity profile for motif DUXA


Sorted Z-values histogram for motif DUXA

Sorted Z-values for motif DUXA



Network of associatons between targets according to the STRING database.



First level regulatory network of DUXA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_70653673 2.143 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr19_+_56280507 0.914 ENST00000341750.4
RFPL4AL1
ret finger protein-like 4A-like 1
chr12_+_6933660 0.741 ENST00000545321.1
GPR162
G protein-coupled receptor 162
chr12_-_114211474 0.722 ENST00000550905.1
ENST00000547963.1
RP11-438N16.1

RP11-438N16.1

chr18_+_44812072 0.712 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1

CTD-2130O13.1

chr6_-_130182410 0.683 ENST00000368143.1
TMEM244
transmembrane protein 244
chrX_-_138072729 0.680 ENST00000455663.1
FGF13
fibroblast growth factor 13
chr12_-_114211444 0.655 ENST00000510694.2
ENST00000550223.1
RP11-438N16.1

RP11-438N16.1

chr6_+_12717892 0.633 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr14_-_80697396 0.624 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr11_-_5526834 0.616 ENST00000380252.1
ENST00000380237.1
ENST00000396895.1
HBG2
HBE1

hemoglobin, gamma G
hemoglobin, epsilon 1

chr22_+_31518938 0.587 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr10_-_61900762 0.505 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr17_-_73937028 0.500 ENST00000586631.2
FBF1
Fas (TNFRSF6) binding factor 1
chr10_+_69865866 0.477 ENST00000354393.2
MYPN
myopalladin
chr16_+_77756399 0.468 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7




nudix (nucleoside diphosphate linked moiety X)-type motif 7




chr15_+_48483736 0.468 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr18_+_61445205 0.423 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr18_+_61445007 0.420 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr12_-_81763184 0.415 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2


protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2


chr3_+_159943362 0.394 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr6_-_138820624 0.385 ENST00000343505.5
NHSL1
NHS-like 1
chr4_-_186732048 0.382 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr18_-_53253112 0.381 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr15_-_65407524 0.379 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr7_-_99277610 0.378 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr15_+_39542867 0.371 ENST00000318578.3
ENST00000561223.1
C15orf54

chromosome 15 open reading frame 54

chr7_+_144015218 0.368 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr2_-_202563414 0.368 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
MPP4


membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)


chr2_-_202563351 0.361 ENST00000602867.1
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr3_-_100565249 0.353 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP


ABI family, member 3 (NESH) binding protein


chr16_+_21716284 0.349 ENST00000388957.3
OTOA
otoancorin
chr7_-_143929936 0.346 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr6_-_134639180 0.343 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr15_+_82380974 0.329 ENST00000559788.1
ENST00000557838.1
RP11-597K23.2

Uncharacterized protein

chr12_-_81763127 0.328 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_+_218683438 0.320 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr11_+_49050504 0.316 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr15_-_80263506 0.303 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr10_-_17171785 0.302 ENST00000377823.1
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr18_-_53253323 0.300 ENST00000540999.1
ENST00000563888.2
TCF4

transcription factor 4

chr14_+_21566980 0.294 ENST00000418511.2
ENST00000554329.2
TMEM253

transmembrane protein 253

chr2_-_231989808 0.284 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr1_-_13452656 0.281 ENST00000376132.3
PRAMEF13
PRAME family member 13
chr6_-_134639042 0.278 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr15_+_71228826 0.276 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49




leucine rich repeat containing 49




chr15_-_75918787 0.268 ENST00000564086.1
SNUPN
snurportin 1
chr7_+_18329712 0.262 ENST00000433709.2
HDAC9
histone deacetylase 9
chr21_+_18811205 0.261 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr2_+_86333340 0.258 ENST00000409783.2
ENST00000409277.3
PTCD3

pentatricopeptide repeat domain 3

chr14_-_83262540 0.243 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr10_-_17171817 0.241 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr6_+_41604620 0.239 ENST00000432027.1
MDFI
MyoD family inhibitor
chr8_-_49833978 0.232 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr8_-_49834299 0.230 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr15_-_75918500 0.222 ENST00000569817.1
SNUPN
snurportin 1
chr13_-_31191642 0.218 ENST00000405805.1
HMGB1
high mobility group box 1
chr2_+_11674213 0.216 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr1_-_117210290 0.215 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chr2_-_74570520 0.209 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
SLC4A5





solute carrier family 4 (sodium bicarbonate cotransporter), member 5





chr11_+_43333513 0.207 ENST00000534695.1
ENST00000455725.2
ENST00000531273.1
ENST00000420461.2
ENST00000378852.3
ENST00000534600.1
API5





apoptosis inhibitor 5





chr17_-_73937116 0.206 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
FBF1


Fas (TNFRSF6) binding factor 1


chr5_-_74326724 0.205 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr8_-_10512569 0.202 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr12_-_75784669 0.196 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2



calcyphosine 2



chr11_-_133826852 0.190 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr21_+_17566643 0.190 ENST00000419952.1
ENST00000445461.2
LINC00478

long intergenic non-protein coding RNA 478

chr17_+_74463650 0.189 ENST00000392492.3
AANAT
aralkylamine N-acetyltransferase
chr4_-_186732241 0.189 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr10_-_112255945 0.188 ENST00000609514.1
ENST00000607952.1
RP11-525A16.4

RP11-525A16.4

chr16_-_21314360 0.187 ENST00000219599.3
ENST00000576703.1
CRYM

crystallin, mu

chr18_+_6774000 0.187 ENST00000532723.1
ARHGAP28
Rho GTPase activating protein 28
chr1_-_13673511 0.183 ENST00000344998.3
ENST00000334600.6
PRAMEF14

PRAME family member 14

chr21_+_30502806 0.179 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr11_+_5372738 0.175 ENST00000380219.1
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr9_-_95298254 0.175 ENST00000444490.2
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr10_+_11865347 0.174 ENST00000277570.5
PROSER2
proline and serine-rich protein 2
chr6_-_88001706 0.169 ENST00000369576.2
GJB7
gap junction protein, beta 7, 25kDa
chrX_-_138724677 0.169 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2


MCF.2 cell line derived transforming sequence


chrX_+_64708615 0.168 ENST00000338957.4
ENST00000423889.3
ZC3H12B

zinc finger CCCH-type containing 12B

chr14_+_20937538 0.167 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr10_+_78078088 0.166 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr16_+_24549014 0.165 ENST00000564314.1
ENST00000567686.1
RBBP6

retinoblastoma binding protein 6

chr12_+_122688090 0.165 ENST00000324189.4
ENST00000546192.1
B3GNT4

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

chr21_-_23058648 0.165 ENST00000416182.1
AF241725.6
AF241725.6
chr1_+_12851545 0.165 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr14_-_80782219 0.163 ENST00000553594.1
DIO2
deiodinase, iodothyronine, type II
chr13_+_98605902 0.162 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5







importin 5







chr4_-_130692631 0.162 ENST00000500092.2
ENST00000509105.1
RP11-519M16.1

RP11-519M16.1

chr21_-_19858196 0.162 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr6_+_31553978 0.161 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1


leukocyte specific transcript 1


chr1_-_42801540 0.160 ENST00000372573.1
FOXJ3
forkhead box J3
chr6_-_75953484 0.157 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2





cytochrome c oxidase subunit VIIa polypeptide 2 (liver)





chr22_+_41697520 0.155 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr1_-_154941350 0.154 ENST00000444179.1
ENST00000414115.1
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr18_-_53253000 0.152 ENST00000566514.1
TCF4
transcription factor 4
chr12_+_57157100 0.152 ENST00000322165.1
HSD17B6
hydroxysteroid (17-beta) dehydrogenase 6
chr6_+_116691001 0.150 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr4_+_147096837 0.149 ENST00000296581.5
ENST00000502781.1
LSM6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr4_-_142134031 0.149 ENST00000420921.2
RNF150
ring finger protein 150
chr11_+_114270752 0.149 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr21_+_47013566 0.148 ENST00000441095.1
ENST00000424569.1
AL133493.2

AL133493.2

chr10_+_90424196 0.148 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
LIPF



lipase, gastric



chr4_-_190948409 0.148 ENST00000504750.1
ENST00000378763.1
FRG2

FSHD region gene 2

chr5_-_150537279 0.148 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6





annexin A6





chr3_+_135969148 0.147 ENST00000251654.4
ENST00000490504.1
ENST00000483687.1
ENST00000468777.1
ENST00000462637.1
ENST00000466072.1
ENST00000482086.1
ENST00000471595.1
ENST00000469217.1
ENST00000465423.1
ENST00000478469.1
PCCB










propionyl CoA carboxylase, beta polypeptide










chr1_-_153113927 0.146 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr11_-_115158193 0.146 ENST00000543540.1
CADM1
cell adhesion molecule 1
chr12_-_12837423 0.145 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr2_+_29001711 0.141 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr2_+_173792893 0.140 ENST00000535187.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr15_+_66679155 0.139 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr3_+_108321623 0.138 ENST00000497905.1
ENST00000463306.1
DZIP3

DAZ interacting zinc finger protein 3

chr13_+_20207782 0.138 ENST00000414242.2
ENST00000361479.5
MPHOSPH8

M-phase phosphoprotein 8

chr5_+_32585605 0.136 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1



SUB1 homolog (S. cerevisiae)



chr13_+_20268547 0.135 ENST00000601204.1
AL354808.2
AL354808.2
chr22_+_27043175 0.134 ENST00000440347.1
ENST00000450203.1
ENST00000430483.1
MIAT


myocardial infarction associated transcript (non-protein coding)


chr22_-_30642728 0.132 ENST00000403987.3
LIF
leukemia inhibitory factor
chr5_-_9712312 0.130 ENST00000506620.1
ENST00000514078.1
ENST00000606744.1
TAS2R1

CTD-2143L24.1
taste receptor, type 2, member 1

CTD-2143L24.1
chr6_+_73076432 0.129 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_77590480 0.129 ENST00000519295.1
ENST00000255194.6
AP3B1

adaptor-related protein complex 3, beta 1 subunit

chr15_+_81589254 0.128 ENST00000394652.2
IL16
interleukin 16
chr1_+_78956651 0.126 ENST00000370757.3
ENST00000370756.3
PTGFR

prostaglandin F receptor (FP)

chr12_-_48963829 0.124 ENST00000301046.2
ENST00000549817.1
LALBA

lactalbumin, alpha-

chr3_-_149093499 0.124 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr2_+_60983361 0.122 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr4_+_148653206 0.122 ENST00000336498.3
ARHGAP10
Rho GTPase activating protein 10
chr10_-_69425399 0.121 ENST00000330298.6
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr4_-_6557336 0.120 ENST00000507294.1
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr6_+_130339710 0.119 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr9_+_34652164 0.118 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chrX_-_122756660 0.116 ENST00000441692.1
THOC2
THO complex 2
chr10_-_50396407 0.116 ENST00000374153.2
ENST00000374151.3
C10orf128

chromosome 10 open reading frame 128

chr21_-_16254231 0.114 ENST00000412426.1
ENST00000418954.1
AF127936.7

AF127936.7

chr2_-_112614424 0.114 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr15_-_65426174 0.113 ENST00000204549.4
PDCD7
programmed cell death 7
chr3_-_12587055 0.112 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr10_-_29923893 0.111 ENST00000355867.4
SVIL
supervillin
chr2_+_86333301 0.110 ENST00000254630.7
PTCD3
pentatricopeptide repeat domain 3
chr13_-_113242439 0.109 ENST00000375669.3
ENST00000261965.3
TUBGCP3

tubulin, gamma complex associated protein 3

chr20_-_44298878 0.109 ENST00000324384.3
ENST00000356562.2
WFDC11

WAP four-disulfide core domain 11

chr10_+_82297658 0.109 ENST00000339284.2
SH2D4B
SH2 domain containing 4B
chr8_+_92114060 0.108 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr3_+_167582561 0.108 ENST00000463642.1
ENST00000464514.1
RP11-298O21.6
RP11-298O21.7
RP11-298O21.6
RP11-298O21.7
chr15_+_53408561 0.108 ENST00000559915.1
RP11-209E8.1
RP11-209E8.1
chrX_+_37639302 0.108 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr7_-_55620433 0.108 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr7_+_116654935 0.105 ENST00000432298.1
ENST00000422922.1
ST7

suppression of tumorigenicity 7

chr10_-_50396357 0.104 ENST00000453436.1
ENST00000474718.1
C10orf128

chromosome 10 open reading frame 128

chr15_+_62853562 0.104 ENST00000561311.1
TLN2
talin 2
chr4_-_69083720 0.103 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr1_-_231560790 0.103 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr1_+_64014588 0.103 ENST00000371086.2
ENST00000340052.3
DLEU2L

deleted in lymphocytic leukemia 2-like

chr8_+_82192501 0.103 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr12_+_26164645 0.102 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr3_-_120461378 0.101 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr6_-_74104816 0.101 ENST00000370363.1
OOEP
oocyte expressed protein
chr1_+_78769549 0.101 ENST00000370758.1
PTGFR
prostaglandin F receptor (FP)
chr12_-_56727676 0.100 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2


PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)


chr7_+_120702819 0.100 ENST00000423795.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr6_-_74104856 0.100 ENST00000441145.1
OOEP
oocyte expressed protein
chr13_+_57721622 0.097 ENST00000377930.1
PRR20B
proline rich 20B
chr10_-_29811456 0.097 ENST00000535393.1
SVIL
supervillin
chr3_-_196242233 0.097 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr14_-_21567009 0.096 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219



zinc finger protein 219



chr5_-_150521192 0.096 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chr3_-_120461353 0.095 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chr3_+_126911974 0.094 ENST00000398112.1
C3orf56
chromosome 3 open reading frame 56
chr13_-_30683005 0.093 ENST00000413591.1
ENST00000432770.1
LINC00365

long intergenic non-protein coding RNA 365

chr6_+_155538093 0.092 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr17_-_79849438 0.092 ENST00000331204.4
ENST00000505490.2
ALYREF

Aly/REF export factor

chr17_-_10276319 0.092 ENST00000252172.4
ENST00000418404.3
MYH13

myosin, heavy chain 13, skeletal muscle

chr6_-_76782371 0.091 ENST00000369950.3
ENST00000369963.3
IMPG1

interphotoreceptor matrix proteoglycan 1

chr19_-_3061397 0.090 ENST00000586839.1
AES
amino-terminal enhancer of split
chr16_-_30006922 0.090 ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chrX_+_37639264 0.089 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr16_-_21222868 0.088 ENST00000574091.1
ENST00000219593.4
ZP2

zona pellucida glycoprotein 2 (sperm receptor)

chr6_-_111888474 0.088 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr7_+_134832808 0.088 ENST00000275767.3
TMEM140
transmembrane protein 140
chr11_-_2924970 0.087 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr7_-_137028534 0.087 ENST00000348225.2
PTN
pleiotrophin
chr12_+_120740119 0.086 ENST00000536460.1
ENST00000202967.4
SIRT4

sirtuin 4

chr11_+_10772534 0.086 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr9_-_5833027 0.086 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr1_+_179050512 0.084 ENST00000367627.3
TOR3A
torsin family 3, member A
chr17_+_7476136 0.084 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
EIF4A1









eukaryotic translation initiation factor 4A1









chr1_-_12908578 0.082 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr12_-_118796971 0.082 ENST00000542902.1
TAOK3
TAO kinase 3
chr11_+_13690200 0.082 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chrX_-_68385274 0.081 ENST00000374584.3
ENST00000590146.1
PJA1

praja ring finger 1, E3 ubiquitin protein ligase

chr16_-_84220633 0.080 ENST00000566732.1
ENST00000561955.1
ENST00000564454.1
ENST00000341690.6
ENST00000541676.1
ENST00000570117.1
ENST00000564345.1
TAF1C






TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa






chr1_-_157811588 0.078 ENST00000368174.4
CD5L
CD5 molecule-like
chr6_-_75960024 0.078 ENST00000370081.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr1_-_117664317 0.078 ENST00000256649.4
ENST00000369464.3
ENST00000485032.1
TRIM45


tripartite motif containing 45


chr18_+_68002675 0.078 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr11_+_13690249 0.077 ENST00000532701.1
FAR1
fatty acyl CoA reductase 1
chr3_+_157827841 0.077 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1




arginine/serine-rich coiled-coil 1




chr3_+_120461484 0.076 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1



general transcription factor IIE, polypeptide 1, alpha 56kDa



chr16_-_84220604 0.076 ENST00000567759.1
TAF1C
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr15_-_66679019 0.076 ENST00000568216.1
ENST00000562124.1
ENST00000570251.1
TIPIN


TIMELESS interacting protein



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.5 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.7 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.5 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 2.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.2 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.2 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.8 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.6 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.2 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0060467 egg activation(GO:0007343) negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.8 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 0.6 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 2.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.0 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins