Motif ID: DMC1

Z-value: 0.177


Transcription factors associated with DMC1:

Gene SymbolEntrez IDGene Name
DMC1 ENSG00000100206.5 DMC1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DMC1hg19_v2_chr22_-_38966123_389661630.742.3e-02Click!


Activity profile for motif DMC1.

activity profile for motif DMC1


Sorted Z-values histogram for motif DMC1

Sorted Z-values for motif DMC1



Network of associatons between targets according to the STRING database.



First level regulatory network of DMC1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_62332357 0.084 ENST00000503366.1
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_69865866 0.081 ENST00000354393.2
 MYPN
myopalladin
chr1_+_166958504 0.065 ENST00000447624.1
 MAEL
maelstrom spermatogenic transposon silencer
chr1_+_166958497 0.059 ENST00000367870.2
 MAEL
maelstrom spermatogenic transposon silencer
chr21_-_46348626 0.059 ENST00000517563.1
 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_166958346 0.054 ENST00000367872.4
 MAEL
maelstrom spermatogenic transposon silencer
chr2_-_75788038 0.052 ENST00000393913.3
ENST00000410113.1
 EVA1A

eva-1 homolog A (C. elegans)

chrX_-_134305322 0.052 ENST00000276241.6
ENST00000344129.2
 CXorf48

cancer/testis antigen 55

chr21_-_46348694 0.050 ENST00000355153.4
ENST00000397850.2
 ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr8_+_67104940 0.044 ENST00000517689.1
 LINC00967
long intergenic non-protein coding RNA 967
chr16_-_85969774 0.040 ENST00000598933.1
 RP11-542M13.3
RP11-542M13.3
chr12_-_8803128 0.038 ENST00000543467.1
 MFAP5
microfibrillar associated protein 5
chr2_-_163008903 0.038 ENST00000418842.2
ENST00000375497.3
 GCG

glucagon

chr3_-_156840776 0.036 ENST00000471357.1
 LINC00880
long intergenic non-protein coding RNA 880
chr3_-_99569821 0.033 ENST00000487087.1
 FILIP1L
filamin A interacting protein 1-like
chr17_-_42875115 0.032 ENST00000591137.1
 CTC-296K1.4
CTC-296K1.4
chr12_-_71031185 0.029 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB


protein tyrosine phosphatase, receptor type, B


chr7_-_15601595 0.027 ENST00000342526.3
 AGMO
alkylglycerol monooxygenase
chr19_+_1041212 0.027 ENST00000433129.1
 ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr12_-_71031220 0.025 ENST00000334414.6
 PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_+_120187465 0.024 ENST00000409826.1
ENST00000417645.1
 TMEM37

transmembrane protein 37

chr2_-_190044480 0.024 ENST00000374866.3
 COL5A2
collagen, type V, alpha 2
chr6_+_88054530 0.023 ENST00000388923.4
 C6orf163
chromosome 6 open reading frame 163
chr11_+_71238313 0.021 ENST00000398536.4
 KRTAP5-7
keratin associated protein 5-7
chr6_-_150067632 0.020 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
 NUP43


nucleoporin 43kDa


chr2_+_219246746 0.019 ENST00000233202.6
 SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr12_-_109025849 0.019 ENST00000228463.6
 SELPLG
selectin P ligand
chr6_-_150067696 0.019 ENST00000340413.2
ENST00000367403.3
 NUP43

nucleoporin 43kDa

chr19_-_3600549 0.019 ENST00000589966.1
 TBXA2R
thromboxane A2 receptor
chr14_-_21624222 0.018 ENST00000304418.3
 OR5AU1
olfactory receptor, family 5, subfamily AU, member 1
chr2_+_219247021 0.018 ENST00000539932.1
 SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr19_+_11466062 0.017 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
 DKFZP761J1410


Lipid phosphate phosphatase-related protein type 2


chr5_+_94727048 0.017 ENST00000283357.5
 FAM81B
family with sequence similarity 81, member B
chr18_+_11857439 0.015 ENST00000602628.1
 GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr6_+_80129989 0.015 ENST00000429444.1
 RP1-232L24.3
RP1-232L24.3
chr2_-_31637560 0.014 ENST00000379416.3
 XDH
xanthine dehydrogenase
chr10_+_17851362 0.014 ENST00000331429.2
ENST00000457317.1
 MRC1L1

cDNA FLJ56855, highly similar to Macrophage mannose receptor 1

chr2_-_21022818 0.014 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
 C2orf43









chromosome 2 open reading frame 43









chr10_-_104597286 0.013 ENST00000369887.3
 CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr2_-_61244308 0.013 ENST00000407787.1
ENST00000398658.2
 PUS10

pseudouridylate synthase 10

chr2_-_61244550 0.013 ENST00000421319.1
 PUS10
pseudouridylate synthase 10
chr12_-_120805872 0.013 ENST00000546985.1
 MSI1
musashi RNA-binding protein 1
chr3_-_141747459 0.011 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
 TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr11_-_85779971 0.011 ENST00000393346.3
 PICALM
phosphatidylinositol binding clathrin assembly protein
chr8_-_101734907 0.010 ENST00000318607.5
ENST00000521865.1
ENST00000520804.1
ENST00000522720.1
ENST00000521067.1
 PABPC1




poly(A) binding protein, cytoplasmic 1




chr10_+_62538089 0.010 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
 CDK1


cyclin-dependent kinase 1


chr17_+_77018896 0.010 ENST00000578229.1
 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr4_+_2800722 0.010 ENST00000508385.1
 SH3BP2
SH3-domain binding protein 2
chr1_-_111061797 0.009 ENST00000369771.2
 KCNA10
potassium voltage-gated channel, shaker-related subfamily, member 10
chr10_+_62538248 0.009 ENST00000448257.2
 CDK1
cyclin-dependent kinase 1
chr3_-_141747950 0.009 ENST00000497579.1
 TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_-_66942617 0.009 ENST00000507298.1
 RP11-83M16.5
RP11-83M16.5
chr17_+_77019030 0.009 ENST00000580454.1
 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr7_-_22539771 0.009 ENST00000406890.2
ENST00000424363.1
 STEAP1B

STEAP family member 1B

chr3_+_9834758 0.009 ENST00000485273.1
ENST00000433034.1
ENST00000397256.1
 ARPC4

ARPC4-TTLL3
actin related protein 2/3 complex, subunit 4, 20kDa

ARPC4-TTLL3 readthrough
chr3_+_101546827 0.008 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
 NFKBIZ


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta


chr14_-_21492113 0.008 ENST00000554094.1
 NDRG2
NDRG family member 2
chr2_-_85641162 0.007 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
 CAPG


capping protein (actin filament), gelsolin-like


chr19_+_1041187 0.007 ENST00000531467.1
 ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr11_-_85780086 0.007 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
 PICALM


phosphatidylinositol binding clathrin assembly protein


chr1_-_47131521 0.006 ENST00000542495.1
ENST00000532925.1
 ATPAF1

ATP synthase mitochondrial F1 complex assembly factor 1

chr14_-_21491477 0.006 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
 NDRG2


NDRG family member 2


chr8_+_145438870 0.006 ENST00000527931.1
 FAM203B
family with sequence similarity 203, member B
chr15_-_61945400 0.005 ENST00000560686.1
 RP11-507B12.1
RP11-507B12.1
chr4_+_106473768 0.005 ENST00000265154.2
ENST00000420470.2
 ARHGEF38

Rho guanine nucleotide exchange factor (GEF) 38

chr12_-_53901266 0.004 ENST00000609999.1
ENST00000267017.3
 NPFF

neuropeptide FF-amide peptide precursor

chr14_-_68157084 0.004 ENST00000557564.1
 RP11-1012A1.4
RP11-1012A1.4
chr10_-_135187193 0.003 ENST00000368547.3
 ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr16_+_2255710 0.003 ENST00000397124.1
ENST00000565250.1
 MLST8

MTOR associated protein, LST8 homolog (S. cerevisiae)

chr14_+_74318513 0.002 ENST00000555228.1
ENST00000555661.1
 PTGR2

prostaglandin reductase 2

chr14_-_21492251 0.002 ENST00000554398.1
 NDRG2
NDRG family member 2
chr10_+_74870253 0.002 ENST00000544879.1
ENST00000537969.1
ENST00000372997.3
 NUDT13


nudix (nucleoside diphosphate linked moiety X)-type motif 13


chr20_+_2796948 0.002 ENST00000361033.1
ENST00000380585.1
 TMEM239

transmembrane protein 239

chr10_-_74856608 0.001 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
 P4HA1





prolyl 4-hydroxylase, alpha polypeptide I





chr12_-_9268707 0.001 ENST00000318602.7
 A2M
alpha-2-macroglobulin
chr2_-_18741882 0.001 ENST00000381249.3
 RDH14
retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr2_+_61244697 0.001 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
 PEX13


peroxisomal biogenesis factor 13


chr17_+_74075263 0.001 ENST00000334586.5
ENST00000392503.2
 ZACN

zinc activated ligand-gated ion channel

chr14_+_74318611 0.001 ENST00000555976.1
ENST00000267568.4
 PTGR2

prostaglandin reductase 2

chr6_+_26383318 0.001 ENST00000469230.1
ENST00000490025.1
ENST00000356709.4
ENST00000352867.2
ENST00000493275.1
ENST00000472507.1
ENST00000482536.1
ENST00000432533.2
ENST00000482842.1
 BTN2A2








butyrophilin, subfamily 2, member A2








chr15_-_49103235 0.000 ENST00000380950.2
 CEP152
centrosomal protein 152kDa
chr17_+_38333263 0.000 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
 RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.0 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)