Motif ID: DLX1_HOXA3_BARX2

Z-value: 0.683

Transcription factors associated with DLX1_HOXA3_BARX2:

Gene SymbolEntrez IDGene Name
BARX2 ENSG00000043039.5 BARX2
DLX1 ENSG00000144355.10 DLX1
HOXA3 ENSG00000105997.18 HOXA3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BARX2hg19_v2_chr11_+_129245796_1292458350.636.9e-02Click!
DLX1hg19_v2_chr2_+_172949468_1729495220.068.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_10022735 1.426 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr4_-_25865159 1.412 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr6_-_32908792 1.217 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr15_+_94899183 1.091 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr9_+_125133315 1.053 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr4_-_36245561 0.998 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_92777606 0.810 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr12_-_10978957 0.774 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr12_-_52761262 0.644 ENST00000257901.3
KRT85
keratin 85
chr9_+_125132803 0.618 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr4_+_169013666 0.601 ENST00000359299.3
ANXA10
annexin A10
chr8_+_92261516 0.595 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr11_+_121447469 0.594 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr10_+_5135981 0.586 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr1_+_81771806 0.573 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr4_-_48116540 0.570 ENST00000506073.1
TXK
TXK tyrosine kinase
chr1_+_28261492 0.534 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr4_+_147145709 0.510 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr12_+_52695617 0.501 ENST00000293525.5
KRT86
keratin 86
chr4_+_86525299 0.496 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr11_+_101918153 0.474 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr5_+_150404904 0.460 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr14_-_54425475 0.443 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr4_+_66536248 0.441 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr10_-_13043697 0.430 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr4_-_109541610 0.423 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr7_+_129984630 0.421 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chrX_-_13835147 0.404 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr2_+_27719697 0.395 ENST00000264717.2
ENST00000424318.2
GCKR

glucokinase (hexokinase 4) regulator

chr5_+_140529630 0.389 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr1_-_232651312 0.386 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr2_+_191221240 0.385 ENST00000409027.1
ENST00000458193.1
INPP1

inositol polyphosphate-1-phosphatase

chr17_+_67498538 0.381 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr18_+_32173276 0.377 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr16_+_58010339 0.374 ENST00000290871.5
ENST00000441824.2
TEPP

testis, prostate and placenta expressed

chr17_-_39123144 0.361 ENST00000355612.2
KRT39
keratin 39
chr6_-_32908765 0.358 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr9_+_113431029 0.351 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK


muscle, skeletal, receptor tyrosine kinase


chr8_+_98900132 0.351 ENST00000520016.1
MATN2
matrilin 2
chr12_-_71533055 0.349 ENST00000552128.1
TSPAN8
tetraspanin 8
chr10_+_6779326 0.347 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr3_+_43020773 0.346 ENST00000488863.1
FAM198A
family with sequence similarity 198, member A
chr12_-_15374343 0.344 ENST00000256953.2
ENST00000546331.1
RERG

RAS-like, estrogen-regulated, growth inhibitor

chr7_+_142982023 0.336 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
TMEM139



transmembrane protein 139



chr6_+_31895254 0.334 ENST00000299367.5
ENST00000442278.2
C2

complement component 2

chr1_-_21620877 0.329 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr8_-_30670384 0.327 ENST00000221138.4
ENST00000518243.1
PPP2CB

protein phosphatase 2, catalytic subunit, beta isozyme

chr9_+_113431059 0.322 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr8_-_41166953 0.319 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr15_+_63682335 0.314 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1

RP11-321G12.1

chr19_-_44388116 0.299 ENST00000587539.1
ZNF404
zinc finger protein 404
chr14_-_54423529 0.298 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr4_-_140544386 0.296 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr11_-_102709441 0.293 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr2_+_158114051 0.276 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_-_153518270 0.272 ENST00000354332.4
ENST00000368716.4
S100A4

S100 calcium binding protein A4

chr10_+_5238793 0.272 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr9_+_130911723 0.272 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr16_-_28937027 0.268 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr1_+_225600404 0.265 ENST00000366845.2
AC092811.1
AC092811.1
chr11_-_121986923 0.264 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr9_+_125133467 0.260 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_130911770 0.258 ENST00000372998.1
LCN2
lipocalin 2
chr2_-_190446738 0.254 ENST00000427419.1
ENST00000455320.1
SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

chr17_-_40337470 0.252 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr5_+_173930676 0.248 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chr4_-_46126093 0.247 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr6_+_31895287 0.244 ENST00000447952.2
C2
complement component 2
chr4_-_19458597 0.243 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr4_+_119810134 0.241 ENST00000434046.2
SYNPO2
synaptopodin 2
chr1_-_183538319 0.237 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr5_+_148443049 0.236 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1

CTC-529P8.1

chr4_-_74486217 0.236 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr10_+_124320195 0.235 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr10_-_5046042 0.235 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr1_-_9953295 0.233 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr3_-_185538849 0.232 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr13_+_78315348 0.228 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr3_-_171528227 0.223 ENST00000356327.5
ENST00000342215.6
ENST00000340989.4
ENST00000351298.4
PLD1



phospholipase D1, phosphatidylcholine-specific



chr7_+_148287657 0.222 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr15_-_88247083 0.218 ENST00000560439.1
RP11-648K4.2
RP11-648K4.2
chr11_+_5710919 0.209 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr1_-_22215192 0.201 ENST00000374673.3
HSPG2
heparan sulfate proteoglycan 2
chr4_-_74486109 0.200 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr8_-_62602327 0.200 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr10_-_50970382 0.199 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr16_-_55866997 0.199 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr4_-_66536196 0.194 ENST00000511294.1
EPHA5
EPH receptor A5
chr3_-_180397256 0.194 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr4_+_41614720 0.192 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr6_-_32157947 0.192 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_+_118398178 0.192 ENST00000302783.4
ENST00000539546.1
TTC36

tetratricopeptide repeat domain 36

chr4_-_66536057 0.191 ENST00000273854.3
EPHA5
EPH receptor A5
chr4_-_39979576 0.191 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr2_-_179672142 0.191 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chr6_-_169654139 0.190 ENST00000366787.3
THBS2
thrombospondin 2
chr7_-_14029283 0.189 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr5_+_140579162 0.187 ENST00000536699.1
ENST00000354757.3
PCDHB11

protocadherin beta 11

chr17_+_62223320 0.187 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr2_+_226273597 0.184 ENST00000409269.2
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr4_+_41614909 0.184 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr10_-_92681033 0.182 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr13_+_78315295 0.179 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr11_+_71900703 0.177 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chrX_+_10126488 0.176 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4


chloride channel, voltage-sensitive 4


chr10_-_14596140 0.176 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr12_-_10605929 0.175 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr6_+_125540951 0.174 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr20_+_19738300 0.173 ENST00000432334.1
RP1-122P22.2
RP1-122P22.2
chr5_-_141249154 0.171 ENST00000357517.5
ENST00000536585.1
PCDH1

protocadherin 1

chr4_+_119809984 0.171 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2


synaptopodin 2


chr11_+_71900572 0.170 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr2_-_101925055 0.168 ENST00000295317.3
RNF149
ring finger protein 149
chr1_+_43613566 0.167 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr4_+_80584903 0.166 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr5_-_53115506 0.166 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1

CTD-2081C10.1

chr14_+_56584414 0.165 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr22_+_18632666 0.164 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr11_+_115498761 0.163 ENST00000424313.2
AP000997.1
AP000997.1
chr2_+_202047843 0.163 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10




caspase 10, apoptosis-related cysteine peptidase




chr2_+_202047596 0.163 ENST00000286186.6
ENST00000360132.3
CASP10

caspase 10, apoptosis-related cysteine peptidase

chr17_-_39150385 0.162 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr6_+_28092338 0.162 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr10_-_105845536 0.157 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr5_+_36606700 0.156 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_+_61151306 0.154 ENST00000580068.1
ENST00000580466.1
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr18_-_74839891 0.154 ENST00000581878.1
MBP
myelin basic protein
chr11_-_36619771 0.151 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr12_-_66317967 0.150 ENST00000601398.1
AC090673.2
Uncharacterized protein
chrX_+_3189861 0.150 ENST00000457435.1
ENST00000420429.2
CXorf28

chromosome X open reading frame 28

chr6_+_26104104 0.149 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chrX_-_1331527 0.149 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2


cytokine receptor-like factor 2


chr7_+_37723420 0.149 ENST00000476620.1
EPDR1
ependymin related 1
chr7_-_14028488 0.149 ENST00000405358.4
ETV1
ets variant 1
chr5_+_36608422 0.148 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_141478242 0.148 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr9_-_95166841 0.145 ENST00000262551.4
OGN
osteoglycin
chr7_+_138915102 0.145 ENST00000486663.1
UBN2
ubinuclein 2
chr15_-_54051831 0.144 ENST00000557913.1
ENST00000360509.5
WDR72

WD repeat domain 72

chr4_-_103749205 0.142 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr17_-_27418537 0.142 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr6_-_36515177 0.141 ENST00000229812.7
STK38
serine/threonine kinase 38
chr11_-_111649074 0.139 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr12_-_15815626 0.138 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr10_-_21186144 0.138 ENST00000377119.1
NEBL
nebulette
chrX_+_27608490 0.137 ENST00000451261.2
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr6_+_26402517 0.137 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr4_+_88896819 0.136 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1



secreted phosphoprotein 1



chr12_-_52585765 0.136 ENST00000313234.5
ENST00000394815.2
KRT80

keratin 80

chr7_-_4923259 0.135 ENST00000536091.1
RADIL
Ras association and DIL domains
chr6_+_83073334 0.134 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr6_-_112575912 0.133 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr16_-_30122717 0.132 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr6_+_30035307 0.131 ENST00000376765.2
ENST00000376763.1
PPP1R11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr2_+_133874577 0.131 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr5_+_173930710 0.131 ENST00000511707.1
RP11-267A15.1
RP11-267A15.1
chr4_-_11431188 0.130 ENST00000510712.1
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr17_-_29645836 0.126 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr6_+_26045603 0.125 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr1_-_211307404 0.125 ENST00000367007.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr17_-_15501932 0.125 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr12_-_64062583 0.125 ENST00000542209.1
DPY19L2
dpy-19-like 2 (C. elegans)
chr14_-_30766223 0.125 ENST00000549360.1
ENST00000508469.2
CTD-2251F13.1

CTD-2251F13.1

chr4_-_175041663 0.125 ENST00000503140.1
RP11-148L24.1
RP11-148L24.1
chr6_-_47445214 0.125 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr9_+_12693336 0.124 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr5_+_67535647 0.124 ENST00000520675.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_140593509 0.124 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr10_-_14590644 0.122 ENST00000378470.1
FAM107B
family with sequence similarity 107, member B
chr6_-_112575687 0.122 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4


laminin, alpha 4


chr5_+_55149150 0.121 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr12_+_8276224 0.121 ENST00000229332.5
CLEC4A
C-type lectin domain family 4, member A
chr4_-_137842536 0.121 ENST00000512039.1
RP11-138I17.1
RP11-138I17.1
chr11_-_74800799 0.120 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr9_-_95166884 0.120 ENST00000375561.5
OGN
osteoglycin
chr4_-_48082192 0.120 ENST00000507351.1
TXK
TXK tyrosine kinase
chr4_+_86396265 0.120 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr10_-_50970322 0.119 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr4_-_120243545 0.119 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr11_+_67219867 0.119 ENST00000438189.2
CABP4
calcium binding protein 4
chr5_+_36608280 0.119 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_61654271 0.118 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr1_-_185597619 0.118 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1

GS1-204I12.1

chr4_-_119759795 0.117 ENST00000419654.2
SEC24D
SEC24 family member D
chr19_-_55150343 0.117 ENST00000456337.1
AC009892.10
Uncharacterized protein
chr4_-_103749179 0.117 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr10_-_24770632 0.116 ENST00000596413.1
AL353583.1
AL353583.1
chr2_-_98972468 0.115 ENST00000454230.1
AC092675.3
Uncharacterized protein
chr1_+_43613612 0.114 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr2_+_102615416 0.113 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr19_+_40873617 0.112 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr6_+_88106840 0.112 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chrX_+_1710484 0.112 ENST00000313871.3
ENST00000381261.3
AKAP17A

A kinase (PRKA) anchor protein 17A

chr2_-_151395525 0.109 ENST00000439275.1
RND3
Rho family GTPase 3
chr6_+_26402465 0.108 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr11_+_327171 0.107 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12


RP11-326C3.12


chr6_-_112575758 0.106 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4



laminin, alpha 4



chr14_-_24711865 0.106 ENST00000399423.4
ENST00000267415.7
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr14_-_24711806 0.106 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2



TERF1 (TRF1)-interacting nuclear factor 2



chr4_-_103749105 0.106 ENST00000394801.4
ENST00000394804.2
UBE2D3

ubiquitin-conjugating enzyme E2D 3


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 0.6 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 0.6 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.7 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 1.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.7 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.4 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.4 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.2 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 1.6 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.0 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.4 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.6 GO:0045550 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.2 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID_ARF6_PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.9 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix