Motif ID: CUX1

Z-value: 1.239


Transcription factors associated with CUX1:

Gene SymbolEntrez IDGene Name
CUX1 ENSG00000257923.5 CUX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CUX1hg19_v2_chr7_+_101459263_1014593100.951.0e-04Click!


Activity profile for motif CUX1.

activity profile for motif CUX1


Sorted Z-values histogram for motif CUX1

Sorted Z-values for motif CUX1



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_47287928 2.345 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr2_+_128377550 1.821 ENST00000437387.1
ENST00000409090.1
MYO7B

myosin VIIB

chr12_-_55378452 1.653 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr17_+_47287749 1.578 ENST00000419580.2
ABI3
ABI family, member 3
chr13_-_46716969 1.471 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_10628117 1.429 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr12_-_55378470 1.330 ENST00000524668.1
ENST00000533607.1
TESPA1

thymocyte expressed, positive selection associated 1

chr11_+_60635035 1.285 ENST00000278853.5
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr3_-_165555200 1.283 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr11_+_117070037 1.277 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chr7_+_106505696 1.142 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr14_+_63671577 1.140 ENST00000555125.1
RHOJ
ras homolog family member J
chr19_-_10628098 1.127 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr1_+_161677034 1.118 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA




Fc receptor-like A




chr19_+_4229495 1.065 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr6_-_32191834 1.029 ENST00000375023.3
NOTCH4
notch 4
chr9_-_117568365 1.028 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr6_+_127898312 1.024 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr14_+_63671105 0.996 ENST00000316754.3
RHOJ
ras homolog family member J
chr1_+_119957554 0.968 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2


chr17_+_38171614 0.966 ENST00000583218.1
ENST00000394149.3
CSF3

colony stimulating factor 3 (granulocyte)

chr1_+_161676739 0.964 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA






Fc receptor-like A






chr3_+_111717600 0.923 ENST00000273368.4
TAGLN3
transgelin 3
chr12_+_49740700 0.913 ENST00000549441.2
ENST00000395069.3
DNAJC22

DnaJ (Hsp40) homolog, subfamily C, member 22

chr9_-_107754034 0.900 ENST00000457720.1
RP11-217B7.3
RP11-217B7.3
chr2_-_113594279 0.897 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr8_+_36641842 0.879 ENST00000523973.1
ENST00000399881.3
KCNU1

potassium channel, subfamily U, member 1

chr18_+_43319467 0.875 ENST00000591541.1
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr6_+_12958137 0.851 ENST00000457702.2
ENST00000379345.2
PHACTR1

phosphatase and actin regulator 1

chr12_-_111358372 0.838 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr6_-_130182410 0.818 ENST00000368143.1
TMEM244
transmembrane protein 244
chr8_+_104384616 0.814 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr1_-_156786634 0.797 ENST00000392306.2
ENST00000368199.3
SH2D2A

SH2 domain containing 2A

chr16_-_85784634 0.755 ENST00000284245.4
ENST00000602914.1
C16orf74

chromosome 16 open reading frame 74

chr11_+_18194384 0.752 ENST00000314254.3
MRGPRX4
MAS-related GPR, member X4
chr22_-_37545972 0.725 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr10_-_61899124 0.708 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_+_78870030 0.692 ENST00000553631.1
ENST00000554719.1
NRXN3

neurexin 3

chr12_-_62586543 0.683 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr17_-_74489215 0.674 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2


rhomboid 5 homolog 2 (Drosophila)


chr14_-_51562037 0.674 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr6_-_142409936 0.655 ENST00000258042.1
NMBR
neuromedin B receptor
chr19_+_51728316 0.646 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33



CD33 molecule



chr1_+_206317450 0.639 ENST00000358184.2
ENST00000361052.3
ENST00000360218.2
CTSE


cathepsin E


chr6_+_7541808 0.634 ENST00000379802.3
DSP
desmoplakin
chr1_+_114522049 0.629 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chr17_+_1665345 0.616 ENST00000576406.1
ENST00000571149.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chrX_-_139866723 0.611 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr15_+_48483736 0.608 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr17_-_42906965 0.598 ENST00000586267.1
GJC1
gap junction protein, gamma 1, 45kDa
chr8_+_105235572 0.594 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr19_-_49149553 0.589 ENST00000084798.4
CA11
carbonic anhydrase XI
chr21_+_47531328 0.586 ENST00000409416.1
ENST00000397763.1
COL6A2

collagen, type VI, alpha 2

chr1_-_9563433 0.576 ENST00000441033.1
RP13-392I16.1
RP13-392I16.1
chr18_+_47088401 0.575 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr17_+_7341586 0.572 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr11_+_111807863 0.565 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr1_+_151129103 0.565 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr12_-_58159361 0.562 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr22_-_20138302 0.551 ENST00000540078.1
ENST00000439765.2
AC006547.14

uncharacterized protein LOC388849

chr16_+_76311169 0.547 ENST00000307431.8
ENST00000377504.4
CNTNAP4

contactin associated protein-like 4

chr6_+_132455118 0.531 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr16_-_30042580 0.528 ENST00000380495.4
FAM57B
family with sequence similarity 57, member B
chr1_+_203096831 0.527 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr3_+_125687987 0.524 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B




rhophilin associated tail protein 1B




chr15_-_72563585 0.522 ENST00000287196.9
ENST00000260376.7
PARP6

poly (ADP-ribose) polymerase family, member 6

chr2_+_113670548 0.522 ENST00000263326.3
ENST00000352179.3
ENST00000349806.3
ENST00000353225.3
IL37



interleukin 37



chr19_-_54604083 0.515 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR





osteoclast associated, immunoglobulin-like receptor





chr1_+_206317591 0.513 ENST00000432969.2
CTSE
cathepsin E
chr17_-_47865948 0.510 ENST00000513602.1
FAM117A
family with sequence similarity 117, member A
chr2_-_218770168 0.499 ENST00000413554.1
TNS1
tensin 1
chr13_-_33760216 0.498 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_+_33883237 0.496 ENST00000505326.1
ENST00000506650.1
RP11-79E3.2

RP11-79E3.2

chr15_+_54793169 0.496 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr22_-_21579843 0.495 ENST00000405188.4
GGT2
gamma-glutamyltransferase 2
chr11_+_45943169 0.474 ENST00000529052.1
ENST00000531526.1
GYLTL1B

glycosyltransferase-like 1B

chr12_-_82153087 0.469 ENST00000547623.1
ENST00000549396.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr19_-_49243845 0.467 ENST00000222145.4
RASIP1
Ras interacting protein 1
chr2_+_168675182 0.467 ENST00000305861.1
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr11_+_7559485 0.467 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr20_+_6748311 0.464 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr3_+_119499331 0.462 ENST00000393716.2
ENST00000466380.1
NR1I2

nuclear receptor subfamily 1, group I, member 2

chr12_-_105478339 0.460 ENST00000424857.2
ENST00000258494.9
ALDH1L2

aldehyde dehydrogenase 1 family, member L2

chr13_-_33924755 0.458 ENST00000439831.1
ENST00000567873.1
STARD13

StAR-related lipid transfer (START) domain containing 13

chr19_-_43099109 0.456 ENST00000599005.1
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr11_-_72385437 0.455 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A


phosphodiesterase 2A, cGMP-stimulated


chr17_+_48243352 0.451 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
SGCA




sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)




chr7_-_143892748 0.448 ENST00000378115.2
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr9_-_33402506 0.442 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7




aquaporin 7




chr3_+_46919235 0.439 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr4_+_120056939 0.437 ENST00000307128.5
MYOZ2
myozenin 2
chr13_+_103451399 0.431 ENST00000257336.1
ENST00000448849.2
BIVM

basic, immunoglobulin-like variable motif containing

chr20_+_13976015 0.428 ENST00000217246.4
MACROD2
MACRO domain containing 2
chr17_-_7081435 0.422 ENST00000380920.4
ASGR1
asialoglycoprotein receptor 1
chr2_-_74781061 0.414 ENST00000264094.3
ENST00000393937.2
ENST00000409986.1
LOXL3


lysyl oxidase-like 3


chrX_-_84634708 0.408 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr16_-_3545424 0.401 ENST00000437192.3
ENST00000399645.3
C16orf90

chromosome 16 open reading frame 90

chr5_+_176784837 0.400 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chr14_+_21569245 0.396 ENST00000556585.2
TMEM253
transmembrane protein 253
chr19_+_45312310 0.395 ENST00000589651.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr14_+_21510385 0.391 ENST00000298690.4
RNASE7
ribonuclease, RNase A family, 7
chr11_+_36589547 0.390 ENST00000299440.5
RAG1
recombination activating gene 1
chr6_-_134499037 0.388 ENST00000528577.1
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_155006224 0.388 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr5_+_132009675 0.387 ENST00000231449.2
ENST00000350025.2
IL4

interleukin 4

chr5_-_135290705 0.387 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr7_-_143991230 0.385 ENST00000543357.1
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr1_+_155006300 0.383 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1



DC-STAMP domain containing 1



chr19_+_54496132 0.382 ENST00000346968.2
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr17_+_7323634 0.381 ENST00000323675.3
SPEM1
spermatid maturation 1
chr12_-_122712038 0.377 ENST00000413918.1
ENST00000443649.3
DIABLO

diablo, IAP-binding mitochondrial protein

chr17_+_1665306 0.376 ENST00000571360.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chrX_+_70316005 0.376 ENST00000374259.3
FOXO4
forkhead box O4
chr7_+_144052381 0.375 ENST00000498580.1
ENST00000056217.5
ARHGEF5

Rho guanine nucleotide exchange factor (GEF) 5

chr9_-_107690420 0.375 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr15_+_91418918 0.372 ENST00000560824.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr12_+_86268065 0.369 ENST00000551529.1
ENST00000256010.6
NTS

neurotensin

chr7_+_130126165 0.368 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr14_-_75389925 0.363 ENST00000556776.1
RPS6KL1
ribosomal protein S6 kinase-like 1
chr12_-_21487829 0.361 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2




solute carrier organic anion transporter family, member 1A2




chr19_+_8117636 0.360 ENST00000253451.4
ENST00000315626.4
CCL25

chemokine (C-C motif) ligand 25

chr12_+_121088291 0.360 ENST00000351200.2
CABP1
calcium binding protein 1
chr3_-_52486841 0.358 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr1_-_150533969 0.357 ENST00000369035.2
ADAMTSL4-AS1
ADAMTSL4 antisense RNA 1
chr10_-_14050522 0.354 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr17_+_65374075 0.353 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr18_+_6774000 0.352 ENST00000532723.1
ARHGAP28
Rho GTPase activating protein 28
chr22_-_32766972 0.351 ENST00000382084.4
ENST00000382086.2
RFPL3S

RFPL3 antisense

chr14_-_51863853 0.348 ENST00000556762.1
RP11-255G12.3
RP11-255G12.3
chr17_-_74533963 0.344 ENST00000293230.5
CYGB
cytoglobin
chr11_+_61583721 0.344 ENST00000257261.6
FADS2
fatty acid desaturase 2
chr7_+_130126012 0.343 ENST00000341441.5
MEST
mesoderm specific transcript
chr13_+_103451548 0.342 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr11_-_60623437 0.340 ENST00000332539.4
PTGDR2
prostaglandin D2 receptor 2
chr22_-_44708731 0.340 ENST00000381176.4
KIAA1644
KIAA1644
chr3_+_142842128 0.338 ENST00000483262.1
RP11-80H8.4
RP11-80H8.4
chrX_-_84634737 0.338 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr6_+_31554962 0.337 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1




leukocyte specific transcript 1




chr1_+_200860122 0.337 ENST00000532631.1
ENST00000451872.2
C1orf106

chromosome 1 open reading frame 106

chr1_-_151032040 0.335 ENST00000540998.1
ENST00000357235.5
CDC42SE1

CDC42 small effector 1

chr12_+_79258547 0.334 ENST00000457153.2
SYT1
synaptotagmin I
chr17_+_7452336 0.334 ENST00000293826.4
TNFSF12-TNFSF13
TNFSF12-TNFSF13 readthrough
chr11_+_60691924 0.331 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A


transmembrane protein 132A


chr19_-_12941469 0.328 ENST00000586969.1
ENST00000589681.1
ENST00000585384.1
ENST00000589808.1
RTBDN



retbindin



chr6_+_72926145 0.328 ENST00000425662.2
ENST00000453976.2
RIMS1

regulating synaptic membrane exocytosis 1

chr1_+_201708992 0.327 ENST00000367295.1
NAV1
neuron navigator 1
chr17_-_42019836 0.326 ENST00000225992.3
PPY
pancreatic polypeptide
chr19_+_41860047 0.326 ENST00000604123.1
TMEM91
transmembrane protein 91
chr2_+_64751433 0.324 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH


aftiphilin


chr17_+_18280976 0.323 ENST00000399134.4
EVPLL
envoplakin-like
chr1_+_153940741 0.323 ENST00000431292.1
CREB3L4
cAMP responsive element binding protein 3-like 4
chr16_+_21716284 0.320 ENST00000388957.3
OTOA
otoancorin
chr20_-_33460621 0.319 ENST00000427420.1
ENST00000336431.5
GGT7

gamma-glutamyltransferase 7

chr5_-_74348371 0.318 ENST00000503568.1
RP11-229C3.2
RP11-229C3.2
chr21_+_45875354 0.314 ENST00000291592.4
LRRC3
leucine rich repeat containing 3
chr19_-_12941215 0.314 ENST00000458671.2
RTBDN
retbindin
chr21_+_39668831 0.313 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr12_+_79258444 0.313 ENST00000261205.4
SYT1
synaptotagmin I
chr3_-_12200851 0.312 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr3_-_99569821 0.309 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr1_+_161676983 0.307 ENST00000367957.2
FCRLA
Fc receptor-like A
chr8_+_75262612 0.307 ENST00000220822.7
GDAP1
ganglioside induced differentiation associated protein 1
chr17_-_8027402 0.306 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7


hes family bHLH transcription factor 7


chr6_+_110501344 0.301 ENST00000368932.1
CDC40
cell division cycle 40
chr21_+_39628852 0.301 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_71182695 0.300 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr22_-_30925150 0.299 ENST00000437871.1
SEC14L6
SEC14-like 6 (S. cerevisiae)
chr9_+_34653861 0.299 ENST00000556792.1
ENST00000318041.9
ENST00000378817.4
IL11RA


interleukin 11 receptor, alpha


chr16_-_56223480 0.298 ENST00000565155.1
RP11-461O7.1
RP11-461O7.1
chr20_-_32308028 0.297 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4


peroxisomal membrane protein 4, 24kDa


chr15_-_31283798 0.296 ENST00000435680.1
ENST00000425768.1
MTMR10

myotubularin related protein 10

chr11_-_117698787 0.295 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr12_+_122018697 0.288 ENST00000541574.1
RP13-941N14.1
RP13-941N14.1
chr19_-_36004543 0.288 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN


dermokine


chr19_-_12941163 0.284 ENST00000589567.1
RTBDN
retbindin
chr6_-_90025011 0.283 ENST00000402938.3
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr8_-_133687778 0.280 ENST00000518642.1
LRRC6
leucine rich repeat containing 6
chr10_-_76859247 0.279 ENST00000472493.2
ENST00000605915.1
ENST00000478873.2
DUSP13


dual specificity phosphatase 13


chr6_-_90024967 0.278 ENST00000602399.1
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr8_-_133687813 0.278 ENST00000250173.1
ENST00000519595.1
LRRC6

leucine rich repeat containing 6

chr1_-_206785789 0.272 ENST00000437518.1
ENST00000367114.3
EIF2D

eukaryotic translation initiation factor 2D

chr3_+_158991025 0.271 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr2_+_60983361 0.271 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr17_+_72211755 0.268 ENST00000529107.1
TTYH2
tweety family member 2
chr15_+_75080883 0.267 ENST00000567571.1
CSK
c-src tyrosine kinase
chr15_-_59981479 0.265 ENST00000607373.1
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr7_-_99527243 0.265 ENST00000312891.2
GJC3
gap junction protein, gamma 3, 30.2kDa
chr9_-_115983641 0.261 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr20_-_43936937 0.259 ENST00000342716.4
ENST00000353917.5
ENST00000360607.6
ENST00000372751.4
MATN4



matrilin 4



chr17_+_67590125 0.259 ENST00000591334.1
AC003051.1
AC003051.1
chr17_+_77021702 0.259 ENST00000392445.2
ENST00000354124.3
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr18_+_72166564 0.259 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2


CNDP dipeptidase 2 (metallopeptidase M20 family)


chr6_+_87865262 0.259 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr14_-_65346555 0.258 ENST00000542895.1
ENST00000556626.1
SPTB

spectrin, beta, erythrocytic

chr13_-_25496926 0.258 ENST00000545981.1
ENST00000381884.4
CENPJ

centromere protein J

chr19_-_35417716 0.258 ENST00000604333.1
CTC-523E23.8
CTC-523E23.8
chr13_-_103451307 0.256 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr3_+_155838337 0.256 ENST00000490337.1
ENST00000389636.5
KCNAB1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr18_-_71815051 0.256 ENST00000582526.1
ENST00000419743.2
FBXO15

F-box protein 15

chr15_-_68498376 0.255 ENST00000540479.1
ENST00000395465.3
CALML4

calmodulin-like 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 3.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.3 1.8 GO:1904970 brush border assembly(GO:1904970)
0.3 1.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 0.7 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.2 0.6 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.6 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.2 0.9 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.2 0.7 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.2 1.0 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.4 GO:0015793 glycerol transport(GO:0015793)
0.1 0.4 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.4 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.9 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 1.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.7 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 2.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.8 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.5 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 1.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 2.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.4 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.4 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.2 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) positive regulation of mast cell cytokine production(GO:0032765) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.3 GO:0060032 notochord regression(GO:0060032)
0.1 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.4 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 1.2 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 1.0 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.2 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) positive regulation of penile erection(GO:0060406)
0.1 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.5 GO:0046618 drug export(GO:0046618)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.8 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 1.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0002784 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 2.4 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.6 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.3 GO:0061511 centriole elongation(GO:0061511)
0.0 0.4 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 1.2 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.7 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.9 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:1903979 regulation of microglial cell activation(GO:1903978) negative regulation of microglial cell activation(GO:1903979)
0.0 0.1 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.4 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0002877 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.4 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 1.7 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.0 0.3 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.2 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.2 GO:0075713 establishment of integrated proviral latency(GO:0075713)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0006935 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 0.0 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.3 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.9 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.0 GO:0003176 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.9 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.2 GO:0033011 perinuclear theca(GO:0033011)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0044305 calyx of Held(GO:0044305)
0.0 1.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 3.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 1.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.2 1.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.2 0.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 2.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 0.9 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0005055 laminin receptor activity(GO:0005055)
0.1 0.9 GO:0015265 urea channel activity(GO:0015265)
0.1 0.9 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 1.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.4 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.1 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.2 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.3 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.2 GO:0019863 IgE binding(GO:0019863)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) BMP receptor binding(GO:0070700)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.0 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 2.2 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.8 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.8 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.0 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 1.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.1 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 3.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 3.7 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.6 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus