Motif ID: CREB5_CREM_JUNB

Z-value: 0.447

Transcription factors associated with CREB5_CREM_JUNB:

Gene SymbolEntrez IDGene Name
CREB5 ENSG00000146592.12 CREB5
CREM ENSG00000095794.15 CREM
JUNB ENSG00000171223.4 JUNB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CREB5hg19_v2_chr7_+_28725585_287256080.863.3e-03Click!
JUNBhg19_v2_chr19_+_12902289_129023100.618.3e-02Click!
CREMhg19_v2_chr10_+_35415851_35415941-0.402.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_56225248 0.594 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr12_+_54378923 0.588 ENST00000303460.4
HOXC10
homeobox C10
chr14_-_80678512 0.485 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr2_-_218706877 0.470 ENST00000446688.1
TNS1
tensin 1
chr12_+_54378849 0.418 ENST00000515593.1
HOXC10
homeobox C10
chr5_+_39520499 0.406 ENST00000604954.1
CTD-2078B5.2
CTD-2078B5.2
chr11_+_117070037 0.404 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chr5_-_54281491 0.396 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr5_-_54281407 0.377 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr5_-_64777733 0.372 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr14_+_63671105 0.370 ENST00000316754.3
RHOJ
ras homolog family member J
chr5_-_147286065 0.330 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr1_+_203274639 0.328 ENST00000290551.4
BTG2
BTG family, member 2
chr17_+_74536115 0.298 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr15_-_72612470 0.282 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr22_+_25003626 0.273 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1


gamma-glutamyltransferase 1


chr5_+_174151536 0.246 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr1_-_161039647 0.244 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr1_-_204165610 0.244 ENST00000367194.4
KISS1
KiSS-1 metastasis-suppressor
chr11_+_66059339 0.243 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr1_-_161039753 0.240 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr17_+_74536164 0.237 ENST00000586148.1
PRCD
progressive rod-cone degeneration
chr1_-_161039456 0.236 ENST00000368016.3
ARHGAP30
Rho GTPase activating protein 30
chr14_-_55738788 0.235 ENST00000556183.1
RP11-665C16.6
RP11-665C16.6
chr22_+_25003606 0.223 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr3_-_99595037 0.221 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chrX_-_31285042 0.210 ENST00000378680.2
ENST00000378723.3
DMD

dystrophin

chr2_-_224467002 0.210 ENST00000421386.1
ENST00000433889.1
SCG2

secretogranin II

chr3_-_99594948 0.210 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr22_+_25003568 0.207 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr3_+_25469802 0.199 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr7_-_45128472 0.194 ENST00000490531.2
NACAD
NAC alpha domain containing
chr9_+_134165195 0.193 ENST00000372261.1
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr3_+_25469724 0.187 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr12_-_110011288 0.178 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr13_-_36429763 0.174 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr2_+_74781828 0.172 ENST00000340004.6
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr3_-_69249863 0.167 ENST00000478263.1
ENST00000462512.1
FRMD4B

FERM domain containing 4B

chr17_+_6918093 0.166 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr7_+_5632436 0.166 ENST00000340250.6
ENST00000382361.3
FSCN1

fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

chrX_-_31285018 0.165 ENST00000361471.4
DMD
dystrophin
chr4_-_186456652 0.164 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr17_+_6918064 0.163 ENST00000546760.1
ENST00000552402.1
C17orf49

chromosome 17 open reading frame 49

chr17_+_6918354 0.163 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr11_+_18720316 0.163 ENST00000280734.2
TMEM86A
transmembrane protein 86A
chr15_-_60884706 0.161 ENST00000449337.2
RORA
RAR-related orphan receptor A
chr15_-_72766533 0.160 ENST00000562573.1
RP11-1007O24.3
RP11-1007O24.3
chr20_+_55099542 0.160 ENST00000371328.3
FAM209A
family with sequence similarity 209, member A
chr5_-_64777685 0.158 ENST00000536360.1
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr12_-_4754356 0.155 ENST00000540967.1
AKAP3
A kinase (PRKA) anchor protein 3
chr2_+_11864458 0.155 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1


lipin 1


chr4_-_186456766 0.153 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr12_+_122150646 0.151 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr6_+_139456226 0.150 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr2_-_74781061 0.147 ENST00000264094.3
ENST00000393937.2
ENST00000409986.1
LOXL3


lysyl oxidase-like 3


chr13_-_52378281 0.144 ENST00000218981.1
DHRS12
dehydrogenase/reductase (SDR family) member 12
chr6_-_127780510 0.143 ENST00000487331.2
ENST00000483725.3
KIAA0408

KIAA0408

chrX_-_31284974 0.143 ENST00000378702.4
DMD
dystrophin
chr3_-_51937331 0.137 ENST00000310914.5
IQCF1
IQ motif containing F1
chr12_-_18890940 0.136 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1





phospholipase C, zeta 1





chr17_-_47841485 0.136 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr17_+_42385927 0.135 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUNDC3A


RUN domain containing 3A


chr13_-_52378231 0.131 ENST00000280056.2
ENST00000444610.2
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr13_-_101327028 0.129 ENST00000328767.5
ENST00000342624.5
ENST00000376234.3
ENST00000423847.1
TMTC4



transmembrane and tetratricopeptide repeat containing 4



chr5_+_156607829 0.128 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr3_-_134092561 0.123 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2


angiomotin like 2


chr17_+_53342311 0.123 ENST00000226067.5
HLF
hepatic leukemia factor
chr20_+_55108302 0.122 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr22_+_31518938 0.121 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr18_+_23806382 0.121 ENST00000400466.2
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr12_+_19389814 0.121 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr11_-_65793948 0.120 ENST00000312106.5
CATSPER1
cation channel, sperm associated 1
chr19_-_51192661 0.116 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr7_-_140624499 0.116 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr2_-_224467093 0.115 ENST00000305409.2
SCG2
secretogranin II
chr18_+_23806437 0.114 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr17_-_46671323 0.113 ENST00000239151.5
HOXB5
homeobox B5
chr16_+_19078960 0.113 ENST00000568985.1
ENST00000566110.1
COQ7

coenzyme Q7 homolog, ubiquinone (yeast)

chrX_+_152953505 0.111 ENST00000253122.5
SLC6A8
solute carrier family 6 (neurotransmitter transporter), member 8
chr3_+_159570722 0.111 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr11_-_77185094 0.111 ENST00000278568.4
ENST00000356341.3
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr12_-_4754318 0.111 ENST00000536414.1
AKAP3
A kinase (PRKA) anchor protein 3
chr1_+_156030937 0.109 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr7_+_142428476 0.108 ENST00000390400.2
TRBV28
T cell receptor beta variable 28
chr14_+_68086515 0.107 ENST00000261783.3
ARG2
arginase 2
chr2_-_216300784 0.106 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr16_+_11343475 0.106 ENST00000572173.1
RMI2
RecQ mediated genome instability 2
chr16_+_29911666 0.105 ENST00000563177.1
ENST00000483405.1
ASPHD1

aspartate beta-hydroxylase domain containing 1

chr7_+_100464760 0.105 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr17_-_56621665 0.103 ENST00000321691.3
C17orf47
chromosome 17 open reading frame 47
chr10_+_77056181 0.102 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1

ZNF503 antisense RNA 1

chr22_+_37959647 0.102 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr2_+_220408724 0.101 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198


transmembrane protein 198


chr2_-_98280383 0.101 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr12_-_4754339 0.101 ENST00000228850.1
AKAP3
A kinase (PRKA) anchor protein 3
chr15_+_75287861 0.100 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5







secretory carrier membrane protein 5







chr16_+_19078911 0.099 ENST00000321998.5
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_158991025 0.095 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr3_+_128598433 0.095 ENST00000308982.7
ENST00000514336.1
ACAD9

acyl-CoA dehydrogenase family, member 9

chr16_+_58535372 0.095 ENST00000566656.1
ENST00000566618.1
NDRG4

NDRG family member 4

chr2_-_74757066 0.094 ENST00000377526.3
AUP1
ancient ubiquitous protein 1
chr2_+_74757050 0.094 ENST00000352222.3
ENST00000437202.1
HTRA2

HtrA serine peptidase 2

chr16_-_3767506 0.094 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr16_-_3767551 0.094 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr6_-_169654139 0.092 ENST00000366787.3
THBS2
thrombospondin 2
chr3_-_100712292 0.092 ENST00000495063.1
ENST00000530539.1
ABI3BP

ABI family, member 3 (NESH) binding protein

chrX_+_48432892 0.092 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr19_-_2702681 0.092 ENST00000382159.3
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr14_+_96671016 0.091 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2



RP11-404P21.8
bradykinin receptor B2



Uncharacterized protein
chr3_-_52312636 0.091 ENST00000296490.3
WDR82
WD repeat domain 82
chr19_+_11649532 0.091 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1


calponin 1, basic, smooth muscle


chr3_-_133614297 0.090 ENST00000486858.1
ENST00000477759.1
RAB6B

RAB6B, member RAS oncogene family

chr7_+_128784712 0.089 ENST00000289407.4
TSPAN33
tetraspanin 33
chr7_+_28448995 0.089 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr20_+_35201993 0.088 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr9_+_134165063 0.088 ENST00000372264.3
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr3_-_52312337 0.088 ENST00000469000.1
WDR82
WD repeat domain 82
chr19_-_49250054 0.088 ENST00000602105.1
ENST00000332955.2
IZUMO1

izumo sperm-egg fusion 1

chr19_+_1954632 0.087 ENST00000589350.1
CSNK1G2
casein kinase 1, gamma 2
chr19_+_24009879 0.087 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr2_-_74601758 0.087 ENST00000407639.2
ENST00000409438.1
DCTN1

dynactin 1

chr7_-_112727774 0.087 ENST00000297146.3
ENST00000501255.2
GPR85

G protein-coupled receptor 85

chr19_-_10341948 0.087 ENST00000592342.1
ENST00000588952.1
ENST00000590320.1
DNMT1

S1PR2
DNA (cytosine-5-)-methyltransferase 1

sphingosine-1-phosphate receptor 2
chr3_-_133614467 0.087 ENST00000469959.1
RAB6B
RAB6B, member RAS oncogene family
chr17_+_7835419 0.086 ENST00000576538.1
ENST00000380262.3
ENST00000563694.1
ENST00000380255.3
ENST00000570782.1
CNTROB




centrobin, centrosomal BRCA2 interacting protein




chr3_-_154042235 0.086 ENST00000308361.6
ENST00000496811.1
ENST00000544526.1
DHX36


DEAH (Asp-Glu-Ala-His) box polypeptide 36


chr16_+_19079215 0.085 ENST00000544894.2
ENST00000561858.1
COQ7

coenzyme Q7 homolog, ubiquinone (yeast)

chr6_-_106773491 0.085 ENST00000360666.4
ATG5
autophagy related 5
chr15_-_66797172 0.085 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4


ribosomal protein L4


chr3_-_155011483 0.084 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr6_-_106773291 0.083 ENST00000343245.3
ATG5
autophagy related 5
chr3_-_100712352 0.083 ENST00000471714.1
ENST00000284322.5
ABI3BP

ABI family, member 3 (NESH) binding protein

chr7_-_6388389 0.083 ENST00000578372.1
FAM220A
family with sequence similarity 220, member A
chr17_+_41177220 0.082 ENST00000587250.2
ENST00000544533.1
RND2

Rho family GTPase 2

chr1_-_204121102 0.082 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr12_-_100660833 0.082 ENST00000551642.1
ENST00000416321.1
ENST00000550587.1
ENST00000549249.1
DEPDC4



DEP domain containing 4



chrX_+_89176881 0.081 ENST00000283891.5
ENST00000561129.2
TGIF2LX

TGFB-induced factor homeobox 2-like, X-linked

chr6_-_99797522 0.081 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr3_-_156878482 0.080 ENST00000295925.4
CCNL1
cyclin L1
chr15_-_63674218 0.080 ENST00000178638.3
CA12
carbonic anhydrase XII
chr9_+_36169380 0.080 ENST00000335119.2
CCIN
calicin
chr11_-_31839488 0.080 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6


paired box 6


chr9_-_33402506 0.079 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7




aquaporin 7




chr3_-_156877997 0.079 ENST00000295926.3
CCNL1
cyclin L1
chr1_-_204121298 0.079 ENST00000367199.2
ETNK2
ethanolamine kinase 2
chr8_+_40010989 0.079 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr16_-_79634595 0.079 ENST00000326043.4
ENST00000393350.1
MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

chr3_+_141457105 0.079 ENST00000480908.1
ENST00000393000.3
RNF7

ring finger protein 7

chr15_-_63674034 0.079 ENST00000344366.3
ENST00000422263.2
CA12

carbonic anhydrase XII

chr19_+_1941117 0.079 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr21_+_17443521 0.078 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr3_+_10068095 0.078 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2



Fanconi anemia, complementation group D2



chr2_+_3705785 0.078 ENST00000252505.3
ALLC
allantoicase
chr3_+_99536663 0.078 ENST00000421999.2
ENST00000463526.1
CMSS1

cms1 ribosomal small subunit homolog (yeast)

chr4_+_146019421 0.078 ENST00000502586.1
ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr6_-_106773610 0.078 ENST00000369076.3
ENST00000369070.1
ATG5

autophagy related 5

chr13_+_111767650 0.078 ENST00000449979.1
ENST00000370623.3
ARHGEF7

Rho guanine nucleotide exchange factor (GEF) 7

chr1_-_204121013 0.077 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr6_+_135818979 0.077 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
LINC00271



long intergenic non-protein coding RNA 271



chr17_-_13505219 0.076 ENST00000284110.1
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr17_+_55333876 0.076 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr16_+_29911864 0.075 ENST00000308748.5
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr11_-_26593779 0.075 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr15_+_66797627 0.074 ENST00000565627.1
ENST00000564179.1
ZWILCH

zwilch kinetochore protein

chr3_-_154042205 0.074 ENST00000329463.5
DHX36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr12_-_92539614 0.074 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr2_-_70520539 0.073 ENST00000482975.2
ENST00000438261.1
SNRPG

small nuclear ribonucleoprotein polypeptide G

chr13_+_111972980 0.073 ENST00000283547.1
TEX29
testis expressed 29
chr2_-_134326009 0.073 ENST00000409261.1
ENST00000409213.1
NCKAP5

NCK-associated protein 5

chr1_-_205391178 0.073 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr3_+_141457030 0.071 ENST00000273480.3
RNF7
ring finger protein 7
chr19_-_39402798 0.071 ENST00000571838.1
CTC-360G5.1
coiled-coil glutamate-rich protein 2
chr2_-_70520832 0.071 ENST00000454893.1
ENST00000272348.2
SNRPG

small nuclear ribonucleoprotein polypeptide G

chr4_+_145567297 0.071 ENST00000434550.2
HHIP
hedgehog interacting protein
chr19_+_49622646 0.070 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr17_+_48046671 0.070 ENST00000505318.2
DLX4
distal-less homeobox 4
chr10_+_35484053 0.070 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM



cAMP responsive element modulator



chr16_+_19079311 0.070 ENST00000569127.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr20_-_14318248 0.069 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr1_-_204119009 0.069 ENST00000444817.1
ETNK2
ethanolamine kinase 2
chr11_+_64004888 0.068 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr15_+_68871308 0.068 ENST00000261861.5
CORO2B
coronin, actin binding protein, 2B
chr1_+_70820451 0.068 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3




HERV-H LTR-associating 3




chr6_-_86353510 0.068 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_-_26593677 0.068 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr15_+_68871569 0.067 ENST00000566799.1
CORO2B
coronin, actin binding protein, 2B
chr7_+_100187196 0.067 ENST00000468962.1
ENST00000427939.2
FBXO24

F-box protein 24

chr6_+_126661253 0.067 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW


centromere protein W


chr13_+_111767582 0.067 ENST00000375741.2
ENST00000375739.2
ARHGEF7

Rho guanine nucleotide exchange factor (GEF) 7

chr20_+_44420617 0.067 ENST00000449078.1
ENST00000456939.1
DNTTIP1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr17_+_74372662 0.067 ENST00000591651.1
ENST00000545180.1
SPHK1

sphingosine kinase 1

chr20_+_44420570 0.065 ENST00000372622.3
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr5_+_32174483 0.065 ENST00000606994.1
CTD-2186M15.3
CTD-2186M15.3
chr17_+_39261584 0.065 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr17_+_7155556 0.064 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
ELP5



elongator acetyltransferase complex subunit 5



chr7_-_142247606 0.064 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr6_-_86352642 0.063 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chrX_+_133941218 0.063 ENST00000370784.4
ENST00000370785.3
FAM122C

family with sequence similarity 122C

chr15_+_66797455 0.063 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr17_-_7835228 0.062 ENST00000303731.4
ENST00000571947.1
ENST00000540486.1
ENST00000572656.1
TRAPPC1



trafficking protein particle complex 1




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 1.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:0090427 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.7 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.0 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:0002877 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.0 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.0 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.0 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.0 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:1901079 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.0 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0044393 microspike(GO:0044393)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.6 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.0 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide