Motif ID: CEBPE_CEBPD

Z-value: 1.227

Transcription factors associated with CEBPE_CEBPD:

Gene SymbolEntrez IDGene Name
CEBPD ENSG00000221869.4 CEBPD
CEBPE ENSG00000092067.5 CEBPE

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CEBPEhg19_v2_chr14_-_23588816_23588836-0.422.6e-01Click!
CEBPDhg19_v2_chr8_-_48651648_48651648-0.324.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPE_CEBPD

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_121944491 2.357 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr12_-_86230315 1.871 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr19_+_6887571 1.640 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1




egf-like module containing, mucin-like, hormone receptor-like 1




chr2_+_102721023 1.614 ENST00000409589.1
ENST00000409329.1
IL1R1

interleukin 1 receptor, type I

chr1_-_111743285 1.430 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr7_+_22766766 1.403 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6






interleukin 6 (interferon, beta 2)






chr8_-_27469196 1.291 ENST00000546343.1
ENST00000560566.1
CLU

clusterin

chr6_+_31895254 1.251 ENST00000299367.5
ENST00000442278.2
C2

complement component 2

chr8_-_27469383 1.242 ENST00000519742.1
CLU
clusterin
chr8_-_27468945 1.239 ENST00000405140.3
CLU
clusterin
chr8_-_27468842 1.223 ENST00000523500.1
CLU
clusterin
chr1_+_169079823 1.178 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_207262170 1.153 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr8_-_27468717 1.128 ENST00000520796.1
ENST00000520491.1
CLU

clusterin

chr4_-_139163491 1.125 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_+_186603355 1.032 ENST00000343098.5
FSIP2
fibrous sheath interacting protein 2
chr11_-_104916034 1.023 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16


caspase recruitment domain family, member 16


chr2_+_186603545 0.992 ENST00000424728.1
FSIP2
fibrous sheath interacting protein 2
chr6_+_31895287 0.889 ENST00000447952.2
C2
complement component 2
chr6_-_32557610 0.889 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr8_+_124194875 0.882 ENST00000522648.1
ENST00000276699.6
FAM83A

family with sequence similarity 83, member A

chr8_+_124194752 0.876 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr5_+_36608422 0.875 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_-_130712995 0.861 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr8_-_11324273 0.858 ENST00000284486.4
FAM167A
family with sequence similarity 167, member A
chr17_+_72427477 0.841 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr6_-_56492816 0.819 ENST00000522360.1
DST
dystonin
chr1_+_82266053 0.788 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr1_-_204183071 0.785 ENST00000308302.3
GOLT1A
golgi transport 1A
chr17_+_72426891 0.727 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_-_190580404 0.709 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr5_-_121413974 0.660 ENST00000231004.4
LOX
lysyl oxidase
chr20_-_52790512 0.656 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr8_+_19536083 0.650 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr8_+_24151553 0.605 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28


ADAM metallopeptidase domain 28


chr3_+_46395219 0.588 ENST00000445132.2
ENST00000292301.4
CCR2

chemokine (C-C motif) receptor 2

chr19_+_11350278 0.573 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr6_+_101847105 0.558 ENST00000369137.3
ENST00000318991.6
GRIK2

glutamate receptor, ionotropic, kainate 2

chr8_-_110660999 0.556 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
SYBU







syntabulin (syntaxin-interacting)







chr6_-_133055896 0.550 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3





vanin 3





chr17_-_34524157 0.549 ENST00000378354.4
ENST00000394484.1
CCL3L3

chemokine (C-C motif) ligand 3-like 3

chr6_+_31895480 0.521 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2

CFB
complement component 2

Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31515337 0.516 ENST00000376148.4
ENST00000376145.4
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr20_-_17662878 0.509 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr2_-_178128250 0.506 ENST00000448782.1
ENST00000446151.2
NFE2L2

nuclear factor, erythroid 2-like 2

chr11_-_104972158 0.492 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1



CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase



caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr2_-_178128199 0.489 ENST00000449627.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr10_-_128994422 0.487 ENST00000522781.1
FAM196A
family with sequence similarity 196, member A
chr4_-_114682719 0.487 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr2_+_113885138 0.485 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr1_-_186649543 0.478 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_178128149 0.467 ENST00000423513.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr4_+_86699834 0.463 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr2_+_33683109 0.449 ENST00000437184.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_-_67597789 0.441 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr15_+_45926919 0.438 ENST00000561735.1
ENST00000260324.7
SQRDL

sulfide quinone reductase-like (yeast)

chr6_-_133055815 0.433 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3






vanin 3






chr2_-_157186630 0.430 ENST00000406048.2
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_-_178128528 0.427 ENST00000397063.4
ENST00000421929.1
NFE2L2

nuclear factor, erythroid 2-like 2

chr14_-_81893734 0.422 ENST00000555447.1
STON2
stonin 2
chr4_-_114682224 0.421 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D




calcium/calmodulin-dependent protein kinase II delta




chr6_+_31895467 0.419 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr4_-_114682936 0.415 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D




calcium/calmodulin-dependent protein kinase II delta




chr5_-_131630931 0.414 ENST00000431054.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr4_-_114682326 0.414 ENST00000505990.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr10_-_92681033 0.401 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr20_-_22566089 0.394 ENST00000377115.4
FOXA2
forkhead box A2
chr17_-_34625719 0.378 ENST00000422211.2
ENST00000542124.1
CCL3L1

chemokine (C-C motif) ligand 3-like 1

chr4_-_114682597 0.377 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr7_-_130597935 0.373 ENST00000447307.1
ENST00000418546.1
MIR29B1

microRNA 29a

chr2_+_65663812 0.372 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1


AC074391.1


chr8_+_24151620 0.371 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr14_-_70263979 0.370 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr2_-_101925055 0.365 ENST00000295317.3
RNF149
ring finger protein 149
chr4_-_114682364 0.353 ENST00000511664.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr15_+_42131011 0.353 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr6_+_101846664 0.347 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2



glutamate receptor, ionotropic, kainate 2



chr6_-_30043539 0.336 ENST00000376751.3
ENST00000244360.6
RNF39

ring finger protein 39

chr11_-_104905840 0.334 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr6_-_113754604 0.332 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr19_+_859654 0.328 ENST00000592860.1
CFD
complement factor D (adipsin)
chr1_+_164528866 0.327 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr5_+_95997885 0.316 ENST00000511097.2
CAST
calpastatin
chr17_-_27181990 0.309 ENST00000583953.1
FAM222B
family with sequence similarity 222, member B
chr8_+_8559406 0.309 ENST00000519106.1
CLDN23
claudin 23
chr7_-_73153178 0.305 ENST00000437775.2
ENST00000222800.3
ABHD11

abhydrolase domain containing 11

chr5_+_95997769 0.303 ENST00000338252.3
ENST00000508830.1
CAST

calpastatin

chr19_+_859425 0.295 ENST00000327726.6
CFD
complement factor D (adipsin)
chr3_-_4793274 0.295 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr17_-_34417479 0.294 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr4_+_55095428 0.290 ENST00000508170.1
ENST00000512143.1
PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

chr12_+_32638897 0.283 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_-_130598059 0.278 ENST00000432045.2
MIR29B1
microRNA 29a
chr20_-_43883197 0.265 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr5_+_95998070 0.260 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST


calpastatin


chr6_-_31940065 0.259 ENST00000375349.3
ENST00000337523.5
DXO

decapping exoribonuclease

chr12_+_48592134 0.259 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr2_-_99279928 0.256 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chrX_-_73512358 0.253 ENST00000602776.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr20_+_4667094 0.248 ENST00000424424.1
ENST00000457586.1
PRNP

prion protein

chr19_-_36019123 0.230 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr1_+_166958497 0.227 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr1_+_166958346 0.220 ENST00000367872.4
MAEL
maelstrom spermatogenic transposon silencer
chr15_-_33447055 0.217 ENST00000559047.1
ENST00000561249.1
FMN1

formin 1

chr5_+_95997918 0.217 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
CAST



calpastatin



chr1_+_10093188 0.215 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chr22_-_20731541 0.212 ENST00000292729.8
USP41
ubiquitin specific peptidase 41
chr14_+_102276192 0.212 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr14_-_38028689 0.208 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr11_-_64510409 0.203 ENST00000394429.1
ENST00000394428.1
RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

chr4_+_96012614 0.203 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_41950342 0.202 ENST00000372587.4
EDN2
endothelin 2
chr17_-_60142609 0.201 ENST00000397786.2
MED13
mediator complex subunit 13
chr17_+_27181956 0.200 ENST00000254928.5
ENST00000580917.2
ERAL1

Era-like 12S mitochondrial rRNA chaperone 1

chr5_-_140013275 0.198 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14


CD14 molecule


chrX_-_73512177 0.198 ENST00000603672.1
ENST00000418855.1
FTX

FTX transcript, XIST regulator (non-protein coding)

chr9_-_94186131 0.197 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr20_+_4666882 0.196 ENST00000379440.4
ENST00000430350.2
PRNP

prion protein

chr1_+_192127578 0.195 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr8_-_42397037 0.192 ENST00000342228.3
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chrX_-_73511908 0.191 ENST00000455395.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr4_+_96012585 0.191 ENST00000502683.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr11_+_62495541 0.187 ENST00000530625.1
ENST00000513247.2
TTC9C

tetratricopeptide repeat domain 9C

chr8_-_25315905 0.186 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chr7_-_73153122 0.183 ENST00000458339.1
ABHD11
abhydrolase domain containing 11
chr7_-_73153161 0.182 ENST00000395147.4
ABHD11
abhydrolase domain containing 11
chrX_+_49126294 0.178 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F



protein phosphatase 1, regulatory subunit 3F



chr1_-_1711508 0.175 ENST00000378625.1
NADK
NAD kinase
chr8_-_134309335 0.173 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1









N-myc downstream regulated 1









chr8_-_134309823 0.170 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr16_-_21663950 0.165 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr5_-_138718973 0.165 ENST00000353963.3
ENST00000348729.3
SLC23A1

solute carrier family 23 (ascorbic acid transporter), member 1

chr13_-_24471641 0.164 ENST00000382145.1
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr10_+_90750493 0.161 ENST00000357339.2
ENST00000355279.2
FAS

Fas cell surface death receptor

chr10_-_116444371 0.160 ENST00000533213.2
ENST00000369252.4
ABLIM1

actin binding LIM protein 1

chr10_+_90750378 0.157 ENST00000355740.2
ENST00000352159.4
FAS

Fas cell surface death receptor

chr5_-_137090028 0.157 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr11_+_62495997 0.157 ENST00000316461.4
TTC9C
tetratricopeptide repeat domain 9C
chr6_-_24489842 0.156 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr18_+_32621324 0.156 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2


microtubule-associated protein, RP/EB family, member 2


chr5_+_98264867 0.153 ENST00000513175.1
CTD-2007H13.3
CTD-2007H13.3
chr2_-_167232484 0.150 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A


sodium channel, voltage-gated, type IX, alpha subunit


chrX_-_40506766 0.150 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38




chromosome X open reading frame 38




chr11_+_65266507 0.146 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr4_+_156775910 0.146 ENST00000506072.1
ENST00000507590.1
TDO2

tryptophan 2,3-dioxygenase

chr19_-_40971643 0.146 ENST00000595483.1
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr1_+_149804218 0.145 ENST00000610125.1
HIST2H4A
histone cluster 2, H4a
chr19_-_40971667 0.141 ENST00000263368.4
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr6_-_84418432 0.140 ENST00000519825.1
ENST00000523484.2
SNAP91

synaptosomal-associated protein, 91kDa

chr1_-_6614565 0.139 ENST00000377705.5
NOL9
nucleolar protein 9
chr1_-_149832704 0.139 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
HIST2H4B


histone cluster 2, H4b


chr5_-_140013224 0.138 ENST00000498971.2
CD14
CD14 molecule
chr20_+_56136136 0.136 ENST00000319441.4
ENST00000543666.1
PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr16_-_21663919 0.136 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr5_-_140013241 0.135 ENST00000519715.1
CD14
CD14 molecule
chr4_-_2935674 0.134 ENST00000514800.1
MFSD10
major facilitator superfamily domain containing 10
chrX_+_46937745 0.134 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN


regucalcin


chr1_-_47697387 0.134 ENST00000371884.2
TAL1
T-cell acute lymphocytic leukemia 1
chr4_+_78079450 0.132 ENST00000395640.1
ENST00000512918.1
CCNG2

cyclin G2

chr4_+_78079570 0.130 ENST00000509972.1
CCNG2
cyclin G2
chr9_-_77502636 0.125 ENST00000449912.2
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr2_-_175711978 0.118 ENST00000409089.2
CHN1
chimerin 1
chr14_+_67708344 0.117 ENST00000557237.1
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr5_-_169407744 0.114 ENST00000377365.3
FAM196B
family with sequence similarity 196, member B
chr3_+_101504200 0.114 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr2_-_209118974 0.113 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1


isocitrate dehydrogenase 1 (NADP+), soluble


chr10_-_82049424 0.112 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr12_+_72058130 0.111 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr2_+_46769798 0.107 ENST00000238738.4
RHOQ
ras homolog family member Q
chr9_-_99381660 0.106 ENST00000375240.3
ENST00000463569.1
CDC14B

cell division cycle 14B

chr6_-_112194484 0.106 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN






FYN oncogene related to SRC, FGR, YES






chr1_+_161087873 0.105 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1



nitrilase 1



chr2_+_135676381 0.105 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
CCNT2


cyclin T2


chr16_-_70323422 0.104 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr8_+_110552337 0.104 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr2_+_219246746 0.101 ENST00000233202.6
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr1_-_45956800 0.100 ENST00000538496.1
TESK2
testis-specific kinase 2
chr11_-_105948040 0.100 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr11_+_82868030 0.096 ENST00000298281.4
ENST00000530660.1
PCF11

PCF11 cleavage and polyadenylation factor subunit

chr15_-_53002007 0.096 ENST00000561490.1
FAM214A
family with sequence similarity 214, member A
chr1_-_228613026 0.095 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chrX_+_48687283 0.094 ENST00000338270.1
ERAS
ES cell expressed Ras
chr10_+_30723105 0.092 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr1_-_45956822 0.092 ENST00000372086.3
ENST00000341771.6
TESK2

testis-specific kinase 2

chr4_-_681114 0.088 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr13_-_28562791 0.086 ENST00000332715.5
URAD
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr12_-_123201337 0.085 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr17_-_61850894 0.084 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47


coiled-coil domain containing 47


chr8_-_6735451 0.083 ENST00000297439.3
DEFB1
defensin, beta 1
chr8_+_110552831 0.082 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr19_+_40871734 0.082 ENST00000359274.5
PLD3
phospholipase D family, member 3
chrX_-_15620192 0.081 ENST00000427411.1
ACE2
angiotensin I converting enzyme 2
chr14_+_64971438 0.081 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr2_+_234296792 0.080 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr12_-_10605929 0.078 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr2_-_201936302 0.076 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B



family with sequence similarity 126, member B



chr3_-_46506358 0.076 ENST00000417439.1
ENST00000431944.1
LTF

lactotransferrin

chr7_-_87936195 0.075 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
STEAP4


STEAP family member 4


chr7_+_150065278 0.074 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1


replication initiator 1


chr10_-_48055018 0.073 ENST00000426610.2
ASAH2C
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2C

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6 2.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.4 GO:1990637 response to prolactin(GO:1990637)
0.3 1.9 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.3 1.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 0.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.5 GO:1902567 astrocyte chemotaxis(GO:0035700) negative regulation of eosinophil activation(GO:1902567) positive regulation of T cell extravasation(GO:2000409) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.2 0.9 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.2 1.2 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.2 0.7 GO:0042369 vitamin D catabolic process(GO:0042369)
0.2 0.5 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of fibroblast growth factor production(GO:0090271) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 2.5 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 0.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.1 1.2 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 1.0 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.4 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.1 1.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.4 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.9 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.5 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 1.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.2 GO:0060585 vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.9 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0060018 positive regulation of chromatin assembly or disassembly(GO:0045799) astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0044010 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0070839 divalent metal ion export(GO:0070839)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.3 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.3 1.8 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0030849 autosome(GO:0030849)
0.1 1.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2 1.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 6.1 GO:0051787 misfolded protein binding(GO:0051787)
0.2 1.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 0.5 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 2.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.5 GO:0089720 caspase binding(GO:0089720)
0.1 0.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 1.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.4 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 2.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 1.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 5.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.7 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.4 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.5 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.2 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.9 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 5.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 1.2 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)