Motif ID: CDX1

Z-value: 0.841


Transcription factors associated with CDX1:

Gene SymbolEntrez IDGene Name
CDX1 ENSG00000113722.12 CDX1



Activity profile for motif CDX1.

activity profile for motif CDX1


Sorted Z-values histogram for motif CDX1

Sorted Z-values for motif CDX1



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_52715179 1.501 ENST00000293670.3
KRT83
keratin 83
chr2_-_207078154 1.393 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr2_+_233527443 1.378 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr7_-_16840820 1.341 ENST00000450569.1
AGR2
anterior gradient 2
chr12_-_52779433 1.309 ENST00000257951.3
KRT84
keratin 84
chr4_+_154622652 0.976 ENST00000260010.6
TLR2
toll-like receptor 2
chr4_-_76957214 0.943 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr6_-_47010061 0.876 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr2_-_207078086 0.854 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr16_-_65106110 0.813 ENST00000562882.1
ENST00000567934.1
CDH11

cadherin 11, type 2, OB-cadherin (osteoblast)

chr4_+_71091786 0.754 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr7_-_92777606 0.724 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr17_+_73717516 0.706 ENST00000200181.3
ENST00000339591.3
ITGB4

integrin, beta 4

chr1_+_81771806 0.698 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr4_-_168155169 0.631 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr8_+_92261516 0.609 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr22_+_21128167 0.590 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_-_179672142 0.588 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chr9_+_77230499 0.584 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr5_+_140602904 0.557 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr5_+_140588269 0.532 ENST00000541609.1
ENST00000239450.2
PCDHB12

protocadherin beta 12

chrX_-_15683147 0.499 ENST00000380342.3
TMEM27
transmembrane protein 27
chr5_+_140579162 0.486 ENST00000536699.1
ENST00000354757.3
PCDHB11

protocadherin beta 11

chr5_-_88120151 0.485 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr5_+_133450365 0.480 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7




transcription factor 7 (T-cell specific, HMG-box)




chr1_+_150254936 0.461 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr1_+_104159999 0.456 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr1_-_207095324 0.455 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr4_-_168155730 0.423 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr2_+_169926047 0.420 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr4_-_168155700 0.411 ENST00000357545.4
ENST00000512648.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr5_+_140739537 0.403 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr17_-_29641104 0.398 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr1_+_169079823 0.395 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_-_75919253 0.389 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr3_+_186285192 0.387 ENST00000439351.1
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr2_-_151344172 0.385 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr10_-_90712520 0.373 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr18_+_32455201 0.372 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr1_-_9953295 0.358 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr2_+_210518057 0.356 ENST00000452717.1
MAP2
microtubule-associated protein 2
chr17_-_29624343 0.355 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr1_-_207095212 0.349 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr5_-_115890554 0.346 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_-_147211226 0.344 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr4_-_52883786 0.339 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr6_-_47009996 0.337 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr10_+_24738355 0.330 ENST00000307544.6
KIAA1217
KIAA1217
chr9_+_35805527 0.324 ENST00000421267.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr18_+_3449695 0.313 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr3_-_186285077 0.305 ENST00000338733.5
TBCCD1
TBCC domain containing 1
chr8_+_38586068 0.303 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1


transforming, acidic coiled-coil containing protein 1


chr1_+_17559776 0.301 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1


peptidyl arginine deiminase, type I


chr14_+_88490894 0.295 ENST00000556033.1
ENST00000553929.1
ENST00000555996.1
ENST00000556673.1
ENST00000557339.1
ENST00000556684.1
RP11-300J18.3





long intergenic non-protein coding RNA 1146





chr4_+_156824840 0.292 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr6_-_15548591 0.291 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr5_+_140571902 0.289 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr14_+_65878650 0.285 ENST00000555559.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr16_+_56691606 0.285 ENST00000334350.6
MT1F
metallothionein 1F
chr2_+_33359687 0.285 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr6_+_36646435 0.284 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
CDKN1A


cyclin-dependent kinase inhibitor 1A (p21, Cip1)


chr8_-_42065075 0.283 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT



plasminogen activator, tissue



chr14_+_65878565 0.280 ENST00000556518.1
ENST00000557164.1
FUT8

fucosyltransferase 8 (alpha (1,6) fucosyltransferase)

chr8_-_42358742 0.279 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr2_+_33359646 0.275 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr8_-_42065187 0.274 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT


plasminogen activator, tissue


chr4_-_22444733 0.268 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr8_+_37553261 0.268 ENST00000331569.4
ZNF703
zinc finger protein 703
chr20_-_17539456 0.262 ENST00000544874.1
ENST00000377868.2
BFSP1

beaded filament structural protein 1, filensin

chr2_+_33359473 0.262 ENST00000432635.1
LTBP1
latent transforming growth factor beta binding protein 1
chr6_+_84222220 0.260 ENST00000369700.3
PRSS35
protease, serine, 35
chrX_+_18725758 0.259 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr7_+_141490017 0.259 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr6_+_84222194 0.257 ENST00000536636.1
PRSS35
protease, serine, 35
chr1_+_12290121 0.249 ENST00000358136.3
ENST00000356315.4
VPS13D

vacuolar protein sorting 13 homolog D (S. cerevisiae)

chr4_+_86748898 0.246 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr8_+_19536083 0.246 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr4_-_110723194 0.245 ENST00000394635.3
CFI
complement factor I
chr12_-_11150474 0.242 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr21_-_43735628 0.240 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr1_-_935491 0.239 ENST00000304952.6
HES4
hes family bHLH transcription factor 4
chr5_+_118691706 0.235 ENST00000415806.2
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr4_+_86749045 0.233 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr12_-_11244912 0.230 ENST00000531678.1
TAS2R43
taste receptor, type 2, member 43
chr5_-_78281623 0.229 ENST00000521117.1
ARSB
arylsulfatase B
chr8_-_120605194 0.223 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_-_110723134 0.222 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr1_+_15986364 0.222 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr8_+_69242957 0.216 ENST00000518698.1
ENST00000539993.1
C8orf34

chromosome 8 open reading frame 34

chr4_-_85654615 0.213 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr4_-_110723335 0.211 ENST00000394634.2
CFI
complement factor I
chr12_+_16500037 0.210 ENST00000536371.1
ENST00000010404.2
MGST1

microsomal glutathione S-transferase 1

chr6_+_33168597 0.210 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr5_+_118691008 0.209 ENST00000504642.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr7_+_141463897 0.208 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr1_+_12524965 0.207 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr4_-_175443943 0.206 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr19_+_46367518 0.206 ENST00000302177.2
FOXA3
forkhead box A3
chr5_+_140165876 0.205 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr8_+_1993173 0.203 ENST00000523438.1
MYOM2
myomesin 2
chr5_+_150639360 0.201 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr17_-_48943706 0.201 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr3_+_182983126 0.193 ENST00000481531.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr6_+_33168637 0.193 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr2_+_181988560 0.191 ENST00000424170.1
ENST00000435411.1
AC104820.2

AC104820.2

chr14_+_102276192 0.184 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr2_+_192543694 0.184 ENST00000435931.1
NABP1
nucleic acid binding protein 1
chr5_+_96079240 0.183 ENST00000515663.1
CAST
calpastatin
chr9_+_77112244 0.183 ENST00000376896.3
RORB
RAR-related orphan receptor B
chr8_+_38585704 0.183 ENST00000519416.1
ENST00000520615.1
TACC1

transforming, acidic coiled-coil containing protein 1

chr3_-_168865522 0.182 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chrX_+_135388147 0.181 ENST00000394141.1
GPR112
G protein-coupled receptor 112
chr12_+_51318513 0.181 ENST00000332160.4
METTL7A
methyltransferase like 7A
chrX_+_13707235 0.177 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr10_-_36813162 0.176 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chrX_-_148571884 0.175 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr2_+_113763031 0.172 ENST00000259211.6
IL36A
interleukin 36, alpha
chr6_-_112575912 0.172 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr2_+_192543153 0.169 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr2_-_158345341 0.169 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr12_+_32654965 0.168 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_-_90049878 0.166 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr7_+_37723420 0.166 ENST00000476620.1
EPDR1
ependymin related 1
chr3_+_182983090 0.166 ENST00000465010.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr2_-_190927447 0.162 ENST00000260950.4
MSTN
myostatin
chr20_+_56136136 0.161 ENST00000319441.4
ENST00000543666.1
PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr5_+_174905398 0.160 ENST00000321442.5
SFXN1
sideroflexin 1
chr2_+_192542879 0.159 ENST00000409510.1
NABP1
nucleic acid binding protein 1
chr1_-_156265438 0.159 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr1_-_197036364 0.158 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr10_-_69597828 0.157 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr8_+_1993152 0.156 ENST00000262113.4
MYOM2
myomesin 2
chr8_-_145047688 0.154 ENST00000356346.3
PLEC
plectin
chr18_+_3449330 0.153 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr5_+_138210919 0.152 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
CTNNA1











catenin (cadherin-associated protein), alpha 1, 102kDa











chr17_+_41005283 0.152 ENST00000592999.1
AOC3
amine oxidase, copper containing 3
chr18_+_13465008 0.150 ENST00000593236.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr17_+_61151306 0.145 ENST00000580068.1
ENST00000580466.1
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr11_+_74811578 0.141 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr12_-_15815626 0.140 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr8_+_103876528 0.139 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2

HCG15011, isoform CRA_a; Protein LOC100996457

chr2_-_177502254 0.139 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr16_+_56672571 0.139 ENST00000290705.8
MT1A
metallothionein 1A
chr3_+_63805017 0.138 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr12_-_90049828 0.136 ENST00000261173.2
ENST00000348959.3
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr5_+_96840389 0.135 ENST00000504012.1
RP11-1E3.1
RP11-1E3.1
chr17_+_28705921 0.135 ENST00000225719.4
CPD
carboxypeptidase D
chrX_+_41548259 0.134 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr6_+_28249299 0.133 ENST00000405948.2
PGBD1
piggyBac transposable element derived 1
chr6_+_28249332 0.133 ENST00000259883.3
PGBD1
piggyBac transposable element derived 1
chr7_-_91794590 0.130 ENST00000430130.2
ENST00000454089.2
LRRD1

leucine-rich repeats and death domain containing 1

chr21_-_43735446 0.130 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr13_-_24476794 0.128 ENST00000382140.2
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr2_-_159237472 0.127 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chrX_-_15619076 0.127 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr7_+_79765071 0.127 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr17_-_41174367 0.127 ENST00000587173.1
VAT1
vesicle amine transport 1
chr18_+_61575200 0.127 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr16_-_18887627 0.126 ENST00000563235.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr10_-_22292613 0.126 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr4_+_69313145 0.125 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr20_+_46130619 0.124 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chr21_-_22175341 0.124 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
LINC00320



long intergenic non-protein coding RNA 320



chr1_+_154975110 0.123 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr5_-_111093759 0.123 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP



neuronal regeneration related protein



chrX_+_99899180 0.123 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr19_+_52076425 0.123 ENST00000436511.2
ZNF175
zinc finger protein 175
chr14_-_23623577 0.122 ENST00000422941.2
ENST00000453702.1
SLC7A8

solute carrier family 7 (amino acid transporter light chain, L system), member 8

chr1_-_15911510 0.121 ENST00000375826.3
AGMAT
agmatine ureohydrolase (agmatinase)
chr2_-_152589670 0.121 ENST00000604864.1
ENST00000603639.1
NEB

nebulin

chr4_-_100485143 0.120 ENST00000394877.3
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr6_+_161123270 0.119 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr1_+_15802594 0.119 ENST00000375910.3
CELA2B
chymotrypsin-like elastase family, member 2B
chr10_+_97733786 0.119 ENST00000371198.2
CC2D2B
coiled-coil and C2 domain containing 2B
chrX_+_15767971 0.118 ENST00000479740.1
ENST00000454127.2
CA5B

carbonic anhydrase VB, mitochondrial

chr5_-_133510456 0.118 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr11_-_61129335 0.117 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3



cytochrome b561 family, member A3



chr15_+_80733570 0.117 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2


aryl-hydrocarbon receptor nuclear translocator 2


chr6_-_33168391 0.115 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB


retinoid X receptor, beta


chr19_+_8455077 0.115 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr12_-_39734783 0.115 ENST00000552961.1
KIF21A
kinesin family member 21A
chr1_+_112016414 0.113 ENST00000343534.5
ENST00000369718.3
C1orf162

chromosome 1 open reading frame 162

chr8_+_21823726 0.113 ENST00000433566.4
XPO7
exportin 7
chrX_+_41548220 0.111 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr9_-_95244781 0.109 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN



asporin



chr11_-_61129723 0.109 ENST00000537680.1
ENST00000426130.2
ENST00000294072.4
CYB561A3


cytochrome b561 family, member A3


chr5_+_102201509 0.109 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr5_-_159766528 0.109 ENST00000505287.2
CCNJL
cyclin J-like
chrX_+_12924732 0.108 ENST00000218032.6
ENST00000311912.5
TLR8

toll-like receptor 8

chr5_-_78281775 0.107 ENST00000396151.3
ENST00000565165.1
ARSB

arylsulfatase B

chr5_+_102201430 0.107 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr9_+_124088860 0.106 ENST00000373806.1
GSN
gelsolin
chr6_+_124125286 0.105 ENST00000368416.1
ENST00000368417.1
ENST00000546092.1
NKAIN2


Na+/K+ transporting ATPase interacting 2


chr4_+_26324474 0.105 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr8_+_67039278 0.105 ENST00000276573.7
ENST00000350034.4
TRIM55

tripartite motif containing 55

chr4_-_100065440 0.104 ENST00000508393.1
ENST00000265512.7
ADH4

alcohol dehydrogenase 4 (class II), pi polypeptide

chr12_+_59989918 0.103 ENST00000547379.1
ENST00000549465.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr17_-_41174424 0.102 ENST00000355653.3
VAT1
vesicle amine transport 1
chr11_-_61687739 0.100 ENST00000531922.1
ENST00000301773.5
RAB3IL1

RAB3A interacting protein (rabin3)-like 1

chr2_-_165424973 0.100 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 1.3 GO:0060480 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.4 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.6 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 2.0 GO:0035878 nail development(GO:0035878)
0.1 0.6 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 1.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.3 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.4 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.3 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.8 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.3 GO:1990034 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0050890 cognition(GO:0050890)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.0 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) positive regulation of estrogen secretion(GO:2000863) regulation of estradiol secretion(GO:2000864) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 1.4 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0006882 cellular zinc ion homeostasis(GO:0006882)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 2.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.9 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.6 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.8 GO:0050436 microfibril binding(GO:0050436)
0.1 1.0 GO:0071723 lipopolysaccharide receptor activity(GO:0001875) lipopeptide binding(GO:0071723)
0.1 0.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 2.2 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.4 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.2 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.1 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.6 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells