Motif ID: CBFB

Z-value: 0.116


Transcription factors associated with CBFB:

Gene SymbolEntrez IDGene Name
CBFB ENSG00000067955.9 CBFB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CBFBhg19_v2_chr16_+_67063262_67063364-0.561.2e-01Click!


Activity profile for motif CBFB.

activity profile for motif CBFB


Sorted Z-values histogram for motif CBFB

Sorted Z-values for motif CBFB



Network of associatons between targets according to the STRING database.



First level regulatory network of CBFB

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_34524093 0.050 ENST00000544425.1
 SPDEF
SAM pointed domain containing ETS transcription factor
chr6_-_34524049 0.049 ENST00000374037.3
 SPDEF
SAM pointed domain containing ETS transcription factor
chr1_+_209859510 0.038 ENST00000367028.2
ENST00000261465.1
 HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr21_+_35107346 0.027 ENST00000456489.1
 ITSN1
intersectin 1 (SH3 domain protein)
chr11_-_58343319 0.026 ENST00000395074.2
 LPXN
leupaxin
chr8_-_60031762 0.021 ENST00000361421.1
 TOX
thymocyte selection-associated high mobility group box
chr12_-_52585765 0.019 ENST00000313234.5
ENST00000394815.2
 KRT80

keratin 80

chr20_+_43343886 0.018 ENST00000190983.4
 WISP2
WNT1 inducible signaling pathway protein 2
chr4_+_88896819 0.018 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
 SPP1



secreted phosphoprotein 1



chr3_+_187957646 0.017 ENST00000457242.1
 LPP
LIM domain containing preferred translocation partner in lipoma
chr14_+_85996471 0.017 ENST00000330753.4
 FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_+_196621156 0.017 ENST00000359637.2
 CFH
complement factor H
chr6_+_27925019 0.015 ENST00000244623.1
 OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr1_+_196621002 0.014 ENST00000367429.4
ENST00000439155.2
 CFH

complement factor H

chrX_-_153718988 0.014 ENST00000263512.4
ENST00000393587.4
ENST00000453912.1
 SLC10A3


solute carrier family 10, member 3


chr15_-_33447055 0.014 ENST00000559047.1
ENST00000561249.1
 FMN1

formin 1

chr14_+_85996507 0.014 ENST00000554746.1
 FLRT2
fibronectin leucine rich transmembrane protein 2
chr4_+_71091786 0.014 ENST00000317987.5
 FDCSP
follicular dendritic cell secreted protein
chr6_-_75912508 0.013 ENST00000416123.2
 COL12A1
collagen, type XII, alpha 1
chr5_+_131396222 0.013 ENST00000296870.2
 IL3
interleukin 3 (colony-stimulating factor, multiple)
chr3_+_98482159 0.012 ENST00000468553.1
 ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_-_152623231 0.012 ENST00000540663.1
ENST00000537033.1
 SYNE1

spectrin repeat containing, nuclear envelope 1

chr12_+_25205446 0.012 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
 LRMP


lymphoid-restricted membrane protein


chr6_+_30908747 0.011 ENST00000462446.1
ENST00000304311.2
 DPCR1

diffuse panbronchiolitis critical region 1

chr2_+_103035102 0.011 ENST00000264260.2
 IL18RAP
interleukin 18 receptor accessory protein
chr7_+_7196565 0.010 ENST00000429911.1
 C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr3_+_98482175 0.010 ENST00000485391.1
ENST00000492254.1
 ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr7_+_117119187 0.010 ENST00000446805.1
 CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr4_-_156297919 0.010 ENST00000450097.1
 MAP9
microtubule-associated protein 9
chr14_-_24977457 0.009 ENST00000250378.3
ENST00000206446.4
 CMA1

chymase 1, mast cell

chr12_+_25205568 0.009 ENST00000548766.1
ENST00000556887.1
 LRMP

lymphoid-restricted membrane protein

chr12_-_53575120 0.009 ENST00000542115.1
 CSAD
cysteine sulfinic acid decarboxylase
chr6_+_45296391 0.008 ENST00000371436.6
ENST00000576263.1
 RUNX2

runt-related transcription factor 2

chr1_-_184006829 0.008 ENST00000361927.4
 COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr2_-_127977654 0.008 ENST00000409327.1
 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr12_-_53594227 0.007 ENST00000550743.2
 ITGB7
integrin, beta 7
chrX_-_70838306 0.007 ENST00000373691.4
ENST00000373693.3
 CXCR3

chemokine (C-X-C motif) receptor 3

chr22_+_42665742 0.007 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
 Z83851.3


Z83851.3


chrX_+_68048803 0.007 ENST00000204961.4
 EFNB1
ephrin-B1
chrX_-_49041242 0.007 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
 PRICKLE3



prickle homolog 3 (Drosophila)



chr11_-_66104237 0.007 ENST00000530056.1
 RIN1
Ras and Rab interactor 1
chr12_+_25205155 0.007 ENST00000550945.1
 LRMP
lymphoid-restricted membrane protein
chr20_+_62492566 0.006 ENST00000369916.3
 ABHD16B
abhydrolase domain containing 16B
chr11_-_1912084 0.006 ENST00000391480.1
 C11orf89
chromosome 11 open reading frame 89
chr3_-_189840223 0.006 ENST00000427335.2
 LEPREL1
leprecan-like 1
chr5_-_137878887 0.006 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
 ETF1



eukaryotic translation termination factor 1



chr14_-_85996332 0.006 ENST00000380722.1
 RP11-497E19.1
RP11-497E19.1
chr5_+_67576109 0.006 ENST00000522084.1
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_184723942 0.005 ENST00000318130.8
 EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr1_+_17634689 0.005 ENST00000375453.1
ENST00000375448.4
 PADI4

peptidyl arginine deiminase, type IV

chr14_-_35183886 0.005 ENST00000298159.6
 CFL2
cofilin 2 (muscle)
chr11_-_66103932 0.005 ENST00000311320.4
 RIN1
Ras and Rab interactor 1
chr12_+_80750652 0.004 ENST00000550182.1
 OTOGL
otogelin-like
chr5_-_108745689 0.004 ENST00000361189.2
 PJA2
praja ring finger 2, E3 ubiquitin protein ligase
chr2_-_207024233 0.004 ENST00000423725.1
ENST00000233190.6
 NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

chr8_-_28747717 0.004 ENST00000416984.2
 INTS9
integrator complex subunit 9
chr11_-_84028180 0.004 ENST00000280241.8
 DLG2
discs, large homolog 2 (Drosophila)
chr11_-_66103867 0.004 ENST00000424433.2
 RIN1
Ras and Rab interactor 1
chr4_-_156297949 0.004 ENST00000515654.1
 MAP9
microtubule-associated protein 9
chr3_+_132843652 0.004 ENST00000508711.1
 TMEM108
transmembrane protein 108
chr20_+_54987168 0.003 ENST00000360314.3
 CASS4
Cas scaffolding protein family member 4
chr5_+_131409476 0.003 ENST00000296871.2
 CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr8_-_28747424 0.003 ENST00000523436.1
ENST00000397363.4
ENST00000521777.1
ENST00000520184.1
ENST00000521022.1
 INTS9




integrator complex subunit 9




chr9_+_15422702 0.003 ENST00000380821.3
ENST00000421710.1
 SNAPC3

small nuclear RNA activating complex, polypeptide 3, 50kDa

chr12_-_54778444 0.003 ENST00000551771.1
 ZNF385A
zinc finger protein 385A
chr11_-_18343725 0.003 ENST00000531848.1
 HPS5
Hermansky-Pudlak syndrome 5
chr2_+_173955327 0.003 ENST00000422149.1
 MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr15_+_49715449 0.003 ENST00000560979.1
 FGF7
fibroblast growth factor 7
chr6_+_42847649 0.002 ENST00000424341.2
ENST00000602561.1
 RPL7L1

ribosomal protein L7-like 1

chr11_-_18343669 0.002 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
 HPS5


Hermansky-Pudlak syndrome 5


chr1_-_179112173 0.002 ENST00000408940.3
ENST00000504405.1
 ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr1_-_240775447 0.002 ENST00000318160.4
 GREM2
gremlin 2, DAN family BMP antagonist
chr11_+_18343800 0.002 ENST00000453096.2
 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr13_-_28674693 0.002 ENST00000537084.1
ENST00000241453.7
ENST00000380982.4
 FLT3


fms-related tyrosine kinase 3


chr20_+_54987305 0.001 ENST00000371336.3
ENST00000434344.1
 CASS4

Cas scaffolding protein family member 4

chr15_+_49715293 0.001 ENST00000267843.4
ENST00000560270.1
 FGF7

fibroblast growth factor 7

chr11_-_64885111 0.001 ENST00000528598.1
ENST00000310597.4
 ZNHIT2

zinc finger, HIT-type containing 2

chr1_-_179112189 0.001 ENST00000512653.1
ENST00000344730.3
 ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr14_-_61116168 0.001 ENST00000247182.6
 SIX1
SIX homeobox 1
chr2_+_207024306 0.001 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
 EEF1B2



eukaryotic translation elongation factor 1 beta 2



chr2_-_87248975 0.001 ENST00000409310.2
ENST00000355705.3
 PLGLB1

plasminogen-like B1

chrX_-_19688475 0.001 ENST00000541422.1
 SH3KBP1
SH3-domain kinase binding protein 1
chr8_+_104384616 0.000 ENST00000520337.1
 CTHRC1
collagen triple helix repeat containing 1
chr8_-_134072593 0.000 ENST00000427060.2
 SLA
Src-like-adaptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)