ISMARA results: BRCA1

Motif ID: BRCA1

Z-value: 0.104

Transcription factors associated with BRCA1:

Gene Symbol	Entrez ID	Gene Name
BRCA1	ENSG00000012048.15	BRCA1

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
BRCA1	hg19_v2_chr17_-_41277317_41277348	-0.55	1.2e-01	Click!

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_121944491	0.115	ENST00000331178.4 ENST00000427185.2 ENST00000442488.2	FEZF1	FEZ family zinc finger 1
chr1_-_173020056	0.044	ENST00000239468.2 ENST00000404377.3	TNFSF18	tumor necrosis factor (ligand) superfamily, member 18
chr11_-_110583912	0.042	ENST00000533353.1 ENST00000527598.1	ARHGAP20	Rho GTPase activating protein 20
chr3_+_184056614	0.041	ENST00000453072.1	FAM131A	family with sequence similarity 131, member A
chr3_+_187461442	0.037	ENST00000450760.1	RP11-211G3.2	RP11-211G3.2
chr9_+_35792151	0.037	ENST00000342694.2	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr8_+_37553261	0.033	ENST00000331569.4	ZNF703	zinc finger protein 703
chr1_-_232598163	0.031	ENST00000308942.4	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr3_-_176914191	0.029	ENST00000437738.1 ENST00000424913.1 ENST00000443315.1	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1
chr20_-_34025999	0.028	ENST00000374369.3	GDF5	growth differentiation factor 5
chr18_+_19749386	0.028	ENST00000269216.3	GATA6	GATA binding protein 6
chr20_+_9049682	0.027	ENST00000334005.3 ENST00000378473.3	PLCB4	phospholipase C, beta 4
chr19_+_55888186	0.026	ENST00000291934.3	TMEM190	transmembrane protein 190
chr3_-_176914238	0.026	ENST00000430069.1 ENST00000428970.1	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1
chr7_-_78400598	0.026	ENST00000536571.1	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_27722021	0.025	ENST00000356660.4 ENST00000418212.1 ENST00000533246.1	BDNF	brain-derived neurotrophic factor
chr8_+_22022653	0.024	ENST00000354870.5 ENST00000397816.3 ENST00000306349.8	BMP1	bone morphogenetic protein 1
chr8_+_22022800	0.024	ENST00000397814.3	BMP1	bone morphogenetic protein 1
chrX_+_10124977	0.022	ENST00000380833.4	CLCN4	chloride channel, voltage-sensitive 4
chr2_+_203879568	0.021	ENST00000449802.1	NBEAL1	neurobeachin-like 1
chr11_-_119234876	0.019	ENST00000525735.1	USP2	ubiquitin specific peptidase 2
chr3_+_185303962	0.018	ENST00000296257.5	SENP2	SUMO1/sentrin/SMT3 specific peptidase 2
chr6_-_137314371	0.017	ENST00000432330.1 ENST00000418699.1	RP11-55K22.5	RP11-55K22.5
chr14_-_60097297	0.017	ENST00000395090.1	RTN1	reticulon 1
chr14_+_103058948	0.017	ENST00000262241.6	RCOR1	REST corepressor 1
chr17_+_36584662	0.016	ENST00000431231.2 ENST00000437668.3	ARHGAP23	Rho GTPase activating protein 23
chr14_-_60097524	0.016	ENST00000342503.4	RTN1	reticulon 1
chr5_-_124082279	0.016	ENST00000513986.1	ZNF608	zinc finger protein 608
chr10_-_36813162	0.016	ENST00000440465.1	NAMPTL	nicotinamide phosphoribosyltransferase-like
chr2_-_158182105	0.015	ENST00000409925.1	ERMN	ermin, ERM-like protein
chr1_+_10271674	0.015	ENST00000377086.1	KIF1B	kinesin family member 1B
chr1_+_63063152	0.015	ENST00000371129.3	ANGPTL3	angiopoietin-like 3
chr13_-_50018140	0.015	ENST00000410043.1 ENST00000347776.5	CAB39L	calcium binding protein 39-like
chrX_-_10851762	0.015	ENST00000380785.1 ENST00000380787.1	MID1	midline 1 (Opitz/BBB syndrome)
chr13_-_50018241	0.014	ENST00000409308.1	CAB39L	calcium binding protein 39-like
chr5_+_139027877	0.013	ENST00000302517.3	CXXC5	CXXC finger protein 5
chr2_-_158182322	0.013	ENST00000420719.2 ENST00000409216.1	ERMN	ermin, ERM-like protein
chr6_-_66417107	0.012	ENST00000370621.3 ENST00000370618.3 ENST00000503581.1 ENST00000393380.2	EYS	eyes shut homolog (Drosophila)
chrX_+_49644470	0.010	ENST00000508866.2	USP27X	ubiquitin specific peptidase 27, X-linked
chr8_+_22462532	0.010	ENST00000389279.3	CCAR2	cell cycle and apoptosis regulator 2
chr12_-_96336369	0.010	ENST00000546947.1 ENST00000546386.1	CCDC38	coiled-coil domain containing 38
chr4_-_48782259	0.010	ENST00000507711.1 ENST00000358350.4 ENST00000537810.1 ENST00000264319.7	FRYL	FRY-like
chr17_-_60142609	0.009	ENST00000397786.2	MED13	mediator complex subunit 13
chr12_-_24715376	0.009	ENST00000446891.2 ENST00000429944.2	RP11-444D3.1	RP11-444D3.1
chr6_-_42981651	0.009	ENST00000244711.3	MEA1	male-enhanced antigen 1
chr17_+_36908984	0.009	ENST00000225426.4 ENST00000579088.1	PSMB3	proteasome (prosome, macropain) subunit, beta type, 3
chr2_+_196521458	0.008	ENST00000409086.3	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr13_-_99910673	0.008	ENST00000397473.2 ENST00000397470.2	GPR18	G protein-coupled receptor 18
chr2_+_196521903	0.007	ENST00000541054.1	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr7_+_44646162	0.007	ENST00000439616.2	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr17_-_27230035	0.007	ENST00000378895.4 ENST00000394901.3	DHRS13	dehydrogenase/reductase (SDR family) member 13
chr7_+_44646177	0.007	ENST00000443864.2 ENST00000447398.1 ENST00000449767.1 ENST00000419661.1	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr19_-_6057282	0.007	ENST00000592281.1	RFX2	regulatory factor X, 2 (influences HLA class II expression)
chr2_+_196521845	0.007	ENST00000359634.5 ENST00000412905.1	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr12_-_49418407	0.006	ENST00000526209.1	KMT2D	lysine (K)-specific methyltransferase 2D
chr2_+_196522032	0.006	ENST00000418005.1	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr19_-_37663332	0.006	ENST00000392157.2	ZNF585A	zinc finger protein 585A
chr2_+_98703595	0.006	ENST00000435344.1	VWA3B	von Willebrand factor A domain containing 3B
chrX_+_150565038	0.005	ENST00000370361.1	VMA21	VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr6_+_42981922	0.005	ENST00000326974.4 ENST00000244670.8	KLHDC3	kelch domain containing 3
chr7_-_99716940	0.005	ENST00000440225.1	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr16_-_790982	0.005	ENST00000301694.5 ENST00000251588.2	NARFL	nuclear prelamin A recognition factor-like
chr5_+_140079919	0.005	ENST00000274712.3	ZMAT2	zinc finger, matrin-type 2
chrX_-_46187069	0.005	ENST00000446884.1	RP1-30G7.2	RP1-30G7.2
chr2_-_134326009	0.004	ENST00000409261.1 ENST00000409213.1	NCKAP5	NCK-associated protein 5
chr14_+_32030582	0.004	ENST00000550649.1 ENST00000281081.7	NUBPL	nucleotide binding protein-like
chr9_-_124976154	0.004	ENST00000482062.1	LHX6	LIM homeobox 6
chr7_-_99716952	0.004	ENST00000523306.1 ENST00000344095.4 ENST00000417349.1 ENST00000493322.1 ENST00000520135.1 ENST00000418432.2 ENST00000460673.2 ENST00000452041.1 ENST00000452438.2 ENST00000451699.1 ENST00000453269.2	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_-_117318788	0.004	ENST00000550505.1	HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)
chr19_-_40324767	0.004	ENST00000601972.1 ENST00000430012.2 ENST00000323039.5 ENST00000348817.3	DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr7_-_78400364	0.004	ENST00000535697.1	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_-_49449107	0.004	ENST00000301067.7	KMT2D	lysine (K)-specific methyltransferase 2D
chr12_-_67072714	0.004	ENST00000545666.1 ENST00000398016.3 ENST00000359742.4 ENST00000286445.7 ENST00000538211.1	GRIP1	glutamate receptor interacting protein 1
chr1_-_227505289	0.004	ENST00000366765.3	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr5_+_139493665	0.003	ENST00000331327.3	PURA	purine-rich element binding protein A
chr16_-_790887	0.003	ENST00000540986.1	NARFL	nuclear prelamin A recognition factor-like
chr5_-_68665296	0.003	ENST00000512152.1 ENST00000503245.1 ENST00000512561.1 ENST00000380822.4	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr9_+_135457530	0.002	ENST00000263610.2	BARHL1	BarH-like homeobox 1
chr10_+_74653330	0.002	ENST00000334011.5	OIT3	oncoprotein induced transcript 3
chr6_+_16129308	0.002	ENST00000356840.3 ENST00000349606.4	MYLIP	myosin regulatory light chain interacting protein
chr3_+_193853927	0.002	ENST00000232424.3	HES1	hes family bHLH transcription factor 1
chr19_-_37663572	0.002	ENST00000588354.1 ENST00000292841.5 ENST00000355533.2 ENST00000356958.4	ZNF585A	zinc finger protein 585A
chr5_-_68665084	0.001	ENST00000509462.1	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr11_+_47291193	0.001	ENST00000428807.1 ENST00000402799.1 ENST00000406482.1 ENST00000349238.3 ENST00000311027.5 ENST00000407859.3 ENST00000395344.3 ENST00000444117.1	MADD	MAP-kinase activating death domain
chr12_+_96196875	0.001	ENST00000553095.1	RP11-536G4.1	Uncharacterized protein
chr7_+_99717230	0.001	ENST00000262932.3	CNPY4	canopy FGF signaling regulator 4
chr5_-_68665469	0.001	ENST00000217893.5	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr20_+_31749574	0.001	ENST00000253362.2	BPIFA2	BPI fold containing family A, member 2
chr11_+_47291645	0.000	ENST00000395336.3 ENST00000402192.2	MADD	MAP-kinase activating death domain
chr14_+_21510385	0.000	ENST00000298690.4	RNASE7	ribonuclease, RNase A family, 7
chr8_-_81083341	0.000	ENST00000519303.2	TPD52	tumor protein D52
chr1_-_160232291	0.000	ENST00000368074.1 ENST00000447377.1	DCAF8	DDB1 and CUL4 associated factor 8
chr2_-_179914760	0.000	ENST00000420890.2 ENST00000409284.1 ENST00000443758.1 ENST00000446116.1	CCDC141	coiled-coil domain containing 141
chr5_-_68664989	0.000	ENST00000508954.1	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa