Motif ID: BPTF

Z-value: 1.300


Transcription factors associated with BPTF:

Gene SymbolEntrez IDGene Name
BPTF ENSG00000171634.12 BPTF

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BPTFhg19_v2_chr17_+_65821780_65821826-0.636.7e-02Click!


Activity profile for motif BPTF.

activity profile for motif BPTF


Sorted Z-values histogram for motif BPTF

Sorted Z-values for motif BPTF



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_46756351 1.991 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_82767583 1.592 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr8_+_85095497 1.167 ENST00000522455.1
ENST00000521695.1
RALYL

RALY RNA binding protein-like

chr8_-_83589388 1.146 ENST00000522776.1
RP11-653B10.1
RP11-653B10.1
chr5_+_82767487 1.137 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr17_+_39975544 1.097 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr8_+_85095769 0.959 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr17_+_39975455 0.913 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_39969183 0.804 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr18_-_56296182 0.799 ENST00000361673.3
ALPK2
alpha-kinase 2
chr1_+_43766642 0.791 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_-_150329421 0.774 ENST00000493969.1
ENST00000328902.5
GIMAP6

GTPase, IMAP family member 6

chr1_-_24438664 0.740 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
MYOM3


myomesin 3


chr11_-_5526834 0.698 ENST00000380252.1
ENST00000380237.1
ENST00000396895.1
HBG2
HBE1

hemoglobin, gamma G
hemoglobin, epsilon 1

chr6_+_106535455 0.694 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr8_+_85618155 0.684 ENST00000523850.1
ENST00000521376.1
RALYL

RALY RNA binding protein-like

chr17_+_39968926 0.668 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10


FK506 binding protein 10, 65 kDa


chr8_+_104383728 0.643 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr3_+_153599269 0.641 ENST00000463297.1
RP11-217E22.5
RP11-217E22.5
chr1_+_43766668 0.623 ENST00000441333.2
ENST00000538015.1
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr7_+_106505912 0.622 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chrX_-_114252193 0.620 ENST00000243213.1
IL13RA2
interleukin 13 receptor, alpha 2
chr4_-_186877806 0.615 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr4_-_70653673 0.599 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr17_+_9479944 0.595 ENST00000396219.3
ENST00000352665.5
WDR16

WD repeat domain 16

chr8_-_82395461 0.589 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr6_-_13290684 0.584 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr3_-_4927447 0.583 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr19_+_49866331 0.572 ENST00000597873.1
DKKL1
dickkopf-like 1
chr8_+_104383759 0.571 ENST00000415886.2
CTHRC1
collagen triple helix repeat containing 1
chr12_-_55367361 0.560 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1


thymocyte expressed, positive selection associated 1


chr19_+_11658655 0.559 ENST00000588935.1
CNN1
calponin 1, basic, smooth muscle
chrX_-_138287168 0.557 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr17_-_76628125 0.542 ENST00000586185.1
ENST00000591384.1
CTD-2357A8.3

CTD-2357A8.3

chr17_-_47286244 0.539 ENST00000503070.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr1_+_153746683 0.537 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr6_-_10115007 0.536 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chrX_-_140673133 0.518 ENST00000370519.3
SPANXA1
sperm protein associated with the nucleus, X-linked, family member A1
chr15_+_55611128 0.518 ENST00000164305.5
ENST00000539642.1
PIGB

phosphatidylinositol glycan anchor biosynthesis, class B

chr20_+_45338126 0.515 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr12_+_54384370 0.513 ENST00000504315.1
HOXC6
homeobox C6
chr6_+_78400375 0.511 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr15_+_55611401 0.503 ENST00000566999.1
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr5_+_166711804 0.496 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr5_+_53686658 0.492 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr7_+_106505696 0.481 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr12_-_111358372 0.477 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr16_+_15528332 0.467 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr5_-_22853429 0.459 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr1_+_151030234 0.455 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr8_-_122653630 0.451 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr5_+_67485704 0.448 ENST00000520762.1
RP11-404L6.2
Uncharacterized protein
chr13_-_33859819 0.437 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_55378470 0.435 ENST00000524668.1
ENST00000533607.1
TESPA1

thymocyte expressed, positive selection associated 1

chr1_-_161207875 0.433 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
















nuclear receptor subfamily 1, group I, member 3
















chr8_+_80209929 0.432 ENST00000519983.1
RP11-1114I9.1
RP11-1114I9.1
chr16_-_11922665 0.432 ENST00000573319.1
ENST00000577041.1
ENST00000574028.1
ENST00000571259.1
ENST00000573037.1
ENST00000571158.1
BCAR4





breast cancer anti-estrogen resistance 4 (non-protein coding)





chr14_-_80677970 0.430 ENST00000438257.4
DIO2
deiodinase, iodothyronine, type II
chr8_+_85095553 0.425 ENST00000521268.1
RALYL
RALY RNA binding protein-like
chr6_+_127898312 0.425 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr15_-_65398647 0.422 ENST00000502113.2
UBAP1L
ubiquitin associated protein 1-like
chr13_+_31309645 0.417 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr4_-_46911248 0.416 ENST00000355591.3
ENST00000505102.1
COX7B2

cytochrome c oxidase subunit VIIb2

chr17_+_7341586 0.414 ENST00000575235.1
FGF11
fibroblast growth factor 11
chrX_+_56644819 0.412 ENST00000446028.1
RP11-431N15.2
RP11-431N15.2
chr2_+_173792893 0.411 ENST00000535187.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_189507523 0.410 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr4_-_186696425 0.402 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr3_-_157217328 0.401 ENST00000392832.2
ENST00000543418.1
VEPH1

ventricular zone expressed PH domain-containing 1

chr2_-_60780702 0.388 ENST00000359629.5
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr4_-_186696515 0.385 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr6_+_62284008 0.383 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr8_-_123706338 0.380 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr15_+_100348193 0.378 ENST00000558188.1
CTD-2054N24.2
Uncharacterized protein
chr3_-_149051444 0.376 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr7_-_41740181 0.373 ENST00000442711.1
INHBA
inhibin, beta A
chrX_-_27417088 0.372 ENST00000608735.1
ENST00000422048.1
RP11-268G12.1

RP11-268G12.1

chr4_-_186696561 0.366 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr22_+_18721427 0.365 ENST00000342888.3
AC008132.1
Uncharacterized protein
chr2_-_36779411 0.363 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr3_-_170587974 0.358 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chrX_+_89176881 0.357 ENST00000283891.5
ENST00000561129.2
TGIF2LX

TGFB-induced factor homeobox 2-like, X-linked

chr11_+_60635035 0.353 ENST00000278853.5
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr18_-_22932080 0.350 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521


zinc finger protein 521


chr15_-_83837983 0.348 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr19_-_55677999 0.347 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr14_-_75079294 0.346 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr16_-_90096309 0.339 ENST00000408886.2
C16orf3
chromosome 16 open reading frame 3
chr19_+_44085189 0.336 ENST00000562365.2
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr19_-_49540073 0.336 ENST00000604577.1
ENST00000591656.1
ENST00000301407.7
ENST00000601167.1
CTB-60B18.6

CGB1

Choriogonadotropin subunit beta variant 1; Uncharacterized protein

chorionic gonadotropin, beta polypeptide 1

chr15_-_102285007 0.335 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr3_-_57260377 0.333 ENST00000495160.2
HESX1
HESX homeobox 1
chr14_-_45722360 0.333 ENST00000451174.1
MIS18BP1
MIS18 binding protein 1
chr14_+_78870030 0.333 ENST00000553631.1
ENST00000554719.1
NRXN3

neurexin 3

chr2_-_70995307 0.333 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
ADD2




adducin 2 (beta)




chr16_+_19619083 0.331 ENST00000538552.1
C16orf62
chromosome 16 open reading frame 62
chr3_+_111630451 0.330 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr11_+_1430983 0.321 ENST00000524702.1
BRSK2
BR serine/threonine kinase 2
chr17_-_46623441 0.320 ENST00000330070.4
HOXB2
homeobox B2
chrX_-_153210107 0.319 ENST00000369997.3
ENST00000393700.3
ENST00000412763.1
RENBP


renin binding protein


chr12_-_42877726 0.319 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr12_+_121088291 0.317 ENST00000351200.2
CABP1
calcium binding protein 1
chr3_-_170588163 0.316 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr3_+_29322803 0.316 ENST00000396583.3
ENST00000383767.2
RBMS3

RNA binding motif, single stranded interacting protein 3

chrX_-_8769378 0.315 ENST00000543214.1
ENST00000381003.3
FAM9A

family with sequence similarity 9, member A

chr15_-_85201779 0.315 ENST00000360476.3
ENST00000394588.3
NMB

neuromedin B

chr20_+_55099542 0.313 ENST00000371328.3
FAM209A
family with sequence similarity 209, member A
chr10_-_22498950 0.309 ENST00000422359.2
EBLN1
endogenous Bornavirus-like nucleoprotein 1
chr7_+_28725585 0.309 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr3_+_189349162 0.307 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63





tumor protein p63





chr19_-_55677920 0.307 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chr20_+_55108302 0.306 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr14_-_80782219 0.304 ENST00000553594.1
DIO2
deiodinase, iodothyronine, type II
chr19_+_4229495 0.302 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr6_-_166309725 0.301 ENST00000545867.1
SDIM1
stress responsive DNAJB4 interacting membrane protein 1
chr11_+_33037401 0.301 ENST00000241051.3
DEPDC7
DEP domain containing 7
chr3_+_29322851 0.301 ENST00000445033.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr1_+_209859510 0.300 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr9_-_140444814 0.300 ENST00000277531.4
PNPLA7
patatin-like phospholipase domain containing 7
chr15_+_63354769 0.297 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr5_+_91378410 0.296 ENST00000507217.1
RP11-348J24.2
RP11-348J24.2
chrY_+_3447082 0.295 ENST00000321217.4
ENST00000559055.2
TGIF2LY

TGFB-induced factor homeobox 2-like, Y-linked

chr15_-_55611306 0.294 ENST00000563262.1
RAB27A
RAB27A, member RAS oncogene family
chr1_-_161277210 0.292 ENST00000491222.2
MPZ
myelin protein zero
chr12_-_42877764 0.287 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr10_-_62493223 0.286 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_62060232 0.286 ENST00000503925.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_27486951 0.283 ENST00000432351.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr17_+_17206635 0.282 ENST00000389022.4
NT5M
5',3'-nucleotidase, mitochondrial
chr6_+_72596604 0.281 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1






regulating synaptic membrane exocytosis 1






chr22_+_44427230 0.280 ENST00000444029.1
PARVB
parvin, beta
chrX_-_32173579 0.280 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD




dystrophin




chr4_-_186696636 0.280 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186697044 0.279 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr12_+_58003935 0.278 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr5_+_156607829 0.275 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr1_+_38022513 0.275 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr5_-_58882219 0.273 ENST00000505453.1
ENST00000360047.5
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_154378049 0.273 ENST00000512471.1
IL6R
interleukin 6 receptor
chr8_+_50081098 0.272 ENST00000518222.1
ENST00000519828.1
RP11-10H3.1

RP11-10H3.1

chr5_-_59481406 0.271 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_73256838 0.270 ENST00000297873.4
WBSCR27
Williams Beuren syndrome chromosome region 27
chr19_-_36391434 0.268 ENST00000396901.1
ENST00000585925.1
NFKBID

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

chr3_+_111260980 0.268 ENST00000438817.2
CD96
CD96 molecule
chr13_-_31039375 0.268 ENST00000399494.1
HMGB1
high mobility group box 1
chr19_+_49535169 0.266 ENST00000474913.1
ENST00000359342.6
CGB2

chorionic gonadotropin, beta polypeptide 2

chr3_+_29323043 0.265 ENST00000452462.1
ENST00000456853.1
RBMS3

RNA binding motif, single stranded interacting protein 3

chr1_+_44514040 0.265 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4

RP5-1198O20.4

chr17_+_74372662 0.265 ENST00000591651.1
ENST00000545180.1
SPHK1

sphingosine kinase 1

chr7_-_112726393 0.265 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85



G protein-coupled receptor 85



chr9_-_117568365 0.259 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chrX_-_80457385 0.259 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr2_+_95537170 0.259 ENST00000295201.4
TEKT4
tektin 4
chr6_-_116866773 0.258 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr16_+_89628778 0.258 ENST00000472354.1
RPL13
ribosomal protein L13
chr3_+_37440653 0.258 ENST00000328376.5
ENST00000452017.2
C3orf35

chromosome 3 open reading frame 35

chr15_-_31521567 0.256 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2


RP11-16E12.2


chr10_-_118897567 0.254 ENST00000369206.5
VAX1
ventral anterior homeobox 1
chr18_-_53089723 0.253 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr5_+_20616500 0.251 ENST00000512688.1
RP11-774D14.1
RP11-774D14.1
chr5_-_135290705 0.251 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr3_-_19988462 0.251 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr9_+_133986782 0.250 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr14_-_95786200 0.250 ENST00000298912.4
CLMN
calmin (calponin-like, transmembrane)
chrX_+_16668278 0.250 ENST00000380200.3
S100G
S100 calcium binding protein G
chr4_-_111536534 0.250 ENST00000503456.1
ENST00000513690.1
RP11-380D23.2

RP11-380D23.2

chr8_+_67405755 0.249 ENST00000521495.1
C8orf46
chromosome 8 open reading frame 46
chr1_-_119530428 0.249 ENST00000369429.3
TBX15
T-box 15
chr14_+_52313833 0.248 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_94942527 0.248 ENST00000448305.2
SERPINA9
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
chr15_-_59500973 0.248 ENST00000560749.1
MYO1E
myosin IE
chr11_-_26593677 0.247 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr2_+_168043793 0.246 ENST00000409273.1
ENST00000409605.1
XIRP2

xin actin-binding repeat containing 2

chr10_-_61899124 0.245 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_+_44084696 0.244 ENST00000562255.1
ENST00000569031.2
PINLYP

phospholipase A2 inhibitor and LY6/PLAUR domain containing

chr19_-_13617247 0.244 ENST00000573710.2
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr5_+_118965244 0.242 ENST00000515256.1
ENST00000509264.1
FAM170A

family with sequence similarity 170, member A

chr22_-_21581926 0.242 ENST00000401924.1
GGT2
gamma-glutamyltransferase 2
chr2_+_70121075 0.242 ENST00000409116.1
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr17_-_7080227 0.241 ENST00000574330.1
ASGR1
asialoglycoprotein receptor 1
chr15_-_83952071 0.241 ENST00000569704.1
BNC1
basonuclin 1
chr19_-_11689752 0.240 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5



acid phosphatase 5, tartrate resistant



chr3_-_100551141 0.239 ENST00000478235.1
ENST00000471901.1
ABI3BP

ABI family, member 3 (NESH) binding protein

chr5_-_1551802 0.239 ENST00000503113.1
CTD-2245E15.3
CTD-2245E15.3
chr2_+_127066059 0.238 ENST00000435352.1
AC023347.1
AC023347.1
chr2_+_173724771 0.237 ENST00000538974.1
ENST00000540783.1
RAPGEF4

Rap guanine nucleotide exchange factor (GEF) 4

chr17_-_7167279 0.236 ENST00000571932.2
CLDN7
claudin 7
chr12_-_57644952 0.236 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3



SH3 and cysteine rich domain 3



chr2_-_70352421 0.235 ENST00000414141.1
AC016700.5
AC016700.5
chr16_-_87812735 0.235 ENST00000570159.1
RP4-536B24.4
RP4-536B24.4
chr4_-_186570679 0.235 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr11_-_33891362 0.234 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr13_-_36920872 0.233 ENST00000451493.1
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr3_-_192445289 0.233 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12



fibroblast growth factor 12



chr4_-_10023095 0.232 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_-_48866517 0.232 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr10_+_120116527 0.230 ENST00000445161.1
LINC00867
long intergenic non-protein coding RNA 867
chr5_+_54398463 0.230 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr13_+_78109884 0.228 ENST00000377246.3
ENST00000349847.3
SCEL

sciellin

chr3_+_189507432 0.226 ENST00000354600.5
TP63
tumor protein p63

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 1.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 1.2 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 0.7 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 0.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.2 0.6 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.2 0.6 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 1.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.8 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.4 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 2.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.1 GO:0018277 protein deamination(GO:0018277)
0.1 0.6 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 2.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.4 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.2 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.1 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.5 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.2 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 1.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.3 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.3 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.2 GO:0042770 signal transduction in response to DNA damage(GO:0042770)
0.1 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 2.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 1.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular response to luteinizing hormone stimulus(GO:0071373)
0.1 0.2 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.1 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.2 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.5 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.3 GO:0021546 rhombomere development(GO:0021546)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.6 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.0 GO:0035711 T-helper 1 cell activation(GO:0035711)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.6 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.3 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.2 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 1.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.6 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.2 GO:0051167 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.6 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0060538 skeletal muscle organ development(GO:0060538)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.2 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:1901750 glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0045655 monocyte differentiation(GO:0030224) regulation of monocyte differentiation(GO:0045655)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:1903516 regulation of single strand break repair(GO:1903516)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0072684 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.1 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.1 GO:0034182 regulation of maintenance of sister chromatid cohesion(GO:0034091) positive regulation of maintenance of sister chromatid cohesion(GO:0034093) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.0 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0050993 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.5 GO:0015671 oxygen transport(GO:0015671)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.0 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.0 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.2 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.2 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.4 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.0 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.6 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.0 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560) positive regulation of platelet aggregation(GO:1901731)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0090656 t-circle formation(GO:0090656)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.0 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.0 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0021510 spinal cord development(GO:0021510)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.0 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.0 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.0 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.0 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.4 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0043486 histone exchange(GO:0043486)
0.0 0.2 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0031401 positive regulation of protein modification process(GO:0031401)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.2 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.0 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.0 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:2000858 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.0 GO:0006566 threonine metabolic process(GO:0006566)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0070993 translation preinitiation complex(GO:0070993)
0.0 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.0 GO:0097451 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0009346 citrate lyase complex(GO:0009346)
0.0 0.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.3 GO:0043005 neuron projection(GO:0043005)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.9 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0043194 axon initial segment(GO:0043194)
0.0 0.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:0097196 Shu complex(GO:0097196)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.0 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0098858 actin-based cell projection(GO:0098858)
0.0 0.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030492 hemoglobin binding(GO:0030492)
0.1 1.0 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 3.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.4 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.1 0.4 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.3 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0008510 inorganic anion exchanger activity(GO:0005452) sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.2 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.1 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.5 GO:0032052 bile acid binding(GO:0032052)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0003774 motor activity(GO:0003774)
0.0 0.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0004057 arginyltransferase activity(GO:0004057)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.0 0.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.0 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.0 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0 0.1 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 1.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0004518 nuclease activity(GO:0004518)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0098505 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.0 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 0.6 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.8 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.4 ST_STAT3_PATHWAY STAT3 Pathway
0.0 1.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.2 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.0 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.7 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.4 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.1 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 1.0 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.9 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.3 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 1.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.8 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.3 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.2 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.8 REACTOME_G2_M_CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 1.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS