Motif ID: BACH2

Z-value: 0.561


Transcription factors associated with BACH2:

Gene SymbolEntrez IDGene Name
BACH2 ENSG00000112182.10 BACH2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BACH2hg19_v2_chr6_-_91006627_910066410.108.0e-01Click!


Activity profile for motif BACH2.

activity profile for motif BACH2


Sorted Z-values histogram for motif BACH2

Sorted Z-values for motif BACH2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_54281491 1.616 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr17_+_47287749 1.537 ENST00000419580.2
ABI3
ABI family, member 3
chr17_-_47287928 1.286 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr14_-_75083313 1.009 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2

CTD-2207P18.2

chr2_-_219858123 0.991 ENST00000453769.1
ENST00000295728.2
ENST00000392096.2
CRYBA2


crystallin, beta A2


chr13_-_36429763 0.923 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr20_+_44637526 0.774 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr3_+_164924716 0.710 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2

RP11-85M11.2

chr5_+_176237478 0.690 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr3_+_124223586 0.513 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr17_+_65375082 0.403 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_+_80317121 0.380 ENST00000333437.4
TEX19
testis expressed 19
chr6_-_113953705 0.360 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr14_-_51863853 0.345 ENST00000556762.1
RP11-255G12.3
RP11-255G12.3
chr17_+_4853442 0.333 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr14_+_69726968 0.325 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr11_+_10476851 0.324 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr3_-_48632593 0.316 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr14_+_69726656 0.309 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr7_-_150721570 0.306 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B



autophagy related 9B



chr12_-_58159361 0.303 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr14_+_69726864 0.297 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr12_-_57871853 0.294 ENST00000549602.1
ENST00000430041.2
ARHGAP9

Rho GTPase activating protein 9

chr5_-_141061759 0.292 ENST00000508305.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_-_9781068 0.286 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr2_+_220495800 0.284 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr3_-_151034734 0.279 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr8_+_104384616 0.278 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr6_+_41604747 0.276 ENST00000419164.1
ENST00000373051.2
MDFI

MyoD family inhibitor

chr2_+_69201705 0.276 ENST00000377938.2
GKN1
gastrokine 1
chr5_-_141061777 0.275 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr17_-_7123021 0.262 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr1_+_154378049 0.250 ENST00000512471.1
IL6R
interleukin 6 receptor
chr18_+_61442629 0.249 ENST00000398019.2
ENST00000540675.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr11_+_10477733 0.249 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr6_+_41604620 0.243 ENST00000432027.1
MDFI
MyoD family inhibitor
chr11_-_65150103 0.238 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45




solute carrier family 25, member 45




chr16_+_15596123 0.228 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr18_+_74207477 0.226 ENST00000532511.1
RP11-17M16.1
uncharacterized protein LOC400658
chr11_-_75201791 0.223 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr3_-_46608010 0.219 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr12_-_95009837 0.210 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr12_-_71182695 0.207 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_-_92951607 0.191 ENST00000427103.1
GFI1
growth factor independent 1 transcription repressor
chr14_+_77425972 0.188 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr1_-_6551720 0.186 ENST00000377728.3
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_-_153521597 0.185 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr17_-_55162360 0.182 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3

RP11-166P13.3

chr12_-_95010147 0.182 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr15_+_57211318 0.180 ENST00000557947.1
TCF12
transcription factor 12
chr1_+_154377669 0.180 ENST00000368485.3
ENST00000344086.4
IL6R

interleukin 6 receptor

chr17_-_7590745 0.179 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr15_-_60690163 0.177 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2



















annexin A2



















chr6_-_119031228 0.174 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L


centrosomal protein 85kDa-like


chr12_-_57872336 0.174 ENST00000552066.1
ARHGAP9
Rho GTPase activating protein 9
chr3_+_164924769 0.172 ENST00000494915.1
RP11-85M11.2
RP11-85M11.2
chr9_-_139922726 0.166 ENST00000265662.5
ENST00000371605.3
ABCA2

ATP-binding cassette, sub-family A (ABC1), member 2

chr1_-_153521714 0.166 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr13_+_113699029 0.165 ENST00000423251.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_-_92952433 0.165 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr13_+_32838801 0.162 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr18_-_74207146 0.162 ENST00000443185.2
ZNF516
zinc finger protein 516
chr9_-_139922631 0.158 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_+_46009837 0.158 ENST00000589627.1
VASP
vasodilator-stimulated phosphoprotein
chr3_+_38388251 0.153 ENST00000427323.1
ENST00000207870.3
ENST00000542835.1
XYLB


xylulokinase homolog (H. influenzae)


chr10_+_104155450 0.153 ENST00000471698.1
ENST00000189444.6
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr3_-_194090460 0.148 ENST00000428839.1
ENST00000347624.3
LRRC15

leucine rich repeat containing 15

chr22_+_42372764 0.147 ENST00000396426.3
ENST00000406029.1
SEPT3

septin 3

chr7_+_134528635 0.144 ENST00000445569.2
CALD1
caldesmon 1
chr16_+_31404624 0.144 ENST00000389202.2
ITGAD
integrin, alpha D
chr11_-_65149422 0.143 ENST00000526432.1
ENST00000527174.1
SLC25A45

solute carrier family 25, member 45

chr11_-_2924720 0.143 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr15_-_72521017 0.141 ENST00000561609.1
PKM
pyruvate kinase, muscle
chr16_+_30077055 0.138 ENST00000564595.2
ENST00000569798.1
ALDOA

aldolase A, fructose-bisphosphate

chr16_+_30077098 0.137 ENST00000395240.3
ENST00000566846.1
ALDOA

aldolase A, fructose-bisphosphate

chr16_+_58533951 0.136 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4










NDRG family member 4










chr8_-_68658578 0.135 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
CPA6


carboxypeptidase A6


chr11_-_102668879 0.134 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr19_-_55881741 0.132 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11


interleukin 11


chr1_-_204121013 0.128 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr1_-_11918988 0.125 ENST00000376468.3
NPPB
natriuretic peptide B
chr1_-_204121102 0.123 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr12_-_48152853 0.121 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr11_-_119066545 0.120 ENST00000415318.1
CCDC153
coiled-coil domain containing 153
chr1_-_204121298 0.119 ENST00000367199.2
ETNK2
ethanolamine kinase 2
chr22_+_42372970 0.118 ENST00000291236.11
SEPT3
septin 3
chr16_-_2908155 0.118 ENST00000571228.1
ENST00000161006.3
PRSS22

protease, serine, 22

chr12_-_8218997 0.118 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr11_-_8739383 0.117 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr12_-_8218926 0.117 ENST00000546241.1
C3AR1
complement component 3a receptor 1
chr12_-_102591604 0.117 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr16_+_30418910 0.115 ENST00000566625.1
ZNF771
zinc finger protein 771
chr2_-_65593784 0.114 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr3_+_48507210 0.111 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1



three prime repair exonuclease 1



chr12_-_48152611 0.111 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr10_+_121410882 0.111 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr17_+_7123125 0.110 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL


acyl-CoA dehydrogenase, very long chain


chr12_-_76478686 0.110 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr19_-_35992780 0.109 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN


dermokine


chr3_-_122512619 0.107 ENST00000383659.1
ENST00000306103.2
HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr17_-_70417365 0.106 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr19_+_49467232 0.106 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9

CTD-2639E6.9

chr10_+_86088381 0.104 ENST00000224756.8
ENST00000372088.2
CCSER2

coiled-coil serine-rich protein 2

chr3_+_48507621 0.104 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr11_+_393428 0.104 ENST00000533249.1
ENST00000527442.1
PKP3

plakophilin 3

chr15_+_41062159 0.104 ENST00000344320.6
C15orf62
chromosome 15 open reading frame 62
chr1_-_235116495 0.103 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr1_-_109968973 0.103 ENST00000271308.4
ENST00000538610.1
PSMA5

proteasome (prosome, macropain) subunit, alpha type, 5

chr16_+_56782118 0.102 ENST00000566678.1
NUP93
nucleoporin 93kDa
chr6_+_135818979 0.102 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
LINC00271



long intergenic non-protein coding RNA 271



chr11_-_47207390 0.102 ENST00000539589.1
ENST00000528462.1
PACSIN3

protein kinase C and casein kinase substrate in neurons 3

chr17_+_7123207 0.102 ENST00000584103.1
ENST00000579886.2
ACADVL

acyl-CoA dehydrogenase, very long chain

chr10_+_134901388 0.096 ENST00000392607.3
GPR123
G protein-coupled receptor 123
chr15_+_75335604 0.095 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chrX_-_16730984 0.095 ENST00000380241.3
CTPS2
CTP synthase 2
chr8_+_123875624 0.094 ENST00000534247.1
ZHX2
zinc fingers and homeoboxes 2
chr21_-_36421626 0.094 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr17_+_79650962 0.093 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr20_+_44034804 0.093 ENST00000357275.2
ENST00000372720.3
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr21_-_36421535 0.092 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1


runt-related transcription factor 1


chr1_-_153935791 0.091 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr16_+_22308717 0.089 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E






polymerase (RNA) III (DNA directed) polypeptide E (80kD)






chr16_+_56781814 0.089 ENST00000568656.1
NUP93
nucleoporin 93kDa
chr7_-_100026280 0.087 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1



zinc finger, CW type with PWWP domain 1



chrX_-_15288154 0.087 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9


ankyrin repeat and SOCS box containing 9


chrX_-_20074895 0.086 ENST00000543767.1
MAP7D2
MAP7 domain containing 2
chr22_+_42372931 0.084 ENST00000328414.8
ENST00000396425.3
SEPT3

septin 3

chr1_+_150480551 0.084 ENST00000369049.4
ENST00000369047.4
ECM1

extracellular matrix protein 1

chr9_+_34992846 0.084 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_+_88854926 0.083 ENST00000298784.1
ENST00000298786.4
FAM35A

family with sequence similarity 35, member A

chr21_+_30672433 0.083 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_220173685 0.082 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN


protein tyrosine phosphatase, receptor type, N


chr10_+_86088337 0.082 ENST00000359979.4
CCSER2
coiled-coil serine-rich protein 2
chr1_-_153935738 0.082 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_158656488 0.080 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr15_+_44829334 0.079 ENST00000535391.1
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr17_+_79651007 0.079 ENST00000572392.1
ENST00000577012.1
HGS

hepatocyte growth factor-regulated tyrosine kinase substrate

chr10_+_88428370 0.079 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chrX_-_16730688 0.077 ENST00000359276.4
CTPS2
CTP synthase 2
chr17_+_75315534 0.076 ENST00000590294.1
ENST00000329047.8
SEPT9

septin 9

chr15_+_44829255 0.076 ENST00000261868.5
ENST00000424492.3
EIF3J

eukaryotic translation initiation factor 3, subunit J

chr6_+_150070857 0.075 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr17_+_55162453 0.075 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1


A kinase (PRKA) anchor protein 1


chr8_-_59572093 0.074 ENST00000427130.2
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr12_+_64845660 0.073 ENST00000331710.5
TBK1
TANK-binding kinase 1
chr1_-_157108130 0.073 ENST00000368192.4
ETV3
ets variant 3
chr3_+_112930946 0.072 ENST00000462425.1
BOC
BOC cell adhesion associated, oncogene regulated
chr15_-_99789736 0.071 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23








tetratricopeptide repeat domain 23








chr4_+_74606223 0.071 ENST00000307407.3
ENST00000401931.1
IL8

interleukin 8

chr1_+_223889285 0.071 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr19_+_7953384 0.070 ENST00000306708.6
LRRC8E
leucine rich repeat containing 8 family, member E
chr2_+_208104497 0.068 ENST00000430494.1
AC007879.7
AC007879.7
chr3_+_191046810 0.068 ENST00000392455.3
ENST00000392456.3
CCDC50

coiled-coil domain containing 50

chr9_-_112179990 0.068 ENST00000394827.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr4_+_76481258 0.068 ENST00000311623.4
ENST00000435974.2
C4orf26

chromosome 4 open reading frame 26

chr1_+_152881014 0.067 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr17_-_73775839 0.067 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B




H3 histone, family 3B (H3.3B)




chr11_-_8739566 0.067 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr15_+_22892663 0.066 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
CYFIP1


cytoplasmic FMR1 interacting protein 1


chr12_+_64845864 0.066 ENST00000538890.1
TBK1
TANK-binding kinase 1
chr6_+_292051 0.066 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr8_-_59572301 0.065 ENST00000038176.3
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr1_-_45272951 0.064 ENST00000372200.1
TCTEX1D4
Tctex1 domain containing 4
chr6_+_150070831 0.064 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_+_150480576 0.064 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr4_-_146019693 0.062 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr9_-_127177703 0.061 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
PSMB7


proteasome (prosome, macropain) subunit, beta type, 7


chr1_+_155107820 0.061 ENST00000484157.1
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr11_-_64013663 0.061 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_+_12308447 0.061 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr21_-_36421401 0.061 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr12_+_7341759 0.061 ENST00000455147.2
ENST00000540398.1
PEX5

peroxisomal biogenesis factor 5

chr16_-_122619 0.060 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr17_-_3461092 0.060 ENST00000301365.4
ENST00000572519.1
TRPV3

transient receptor potential cation channel, subfamily V, member 3

chr12_+_64846129 0.060 ENST00000540417.1
ENST00000539810.1
TBK1

TANK-binding kinase 1

chr7_+_30960915 0.060 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1


aquaporin 1 (Colton blood group)


chr11_-_6341844 0.058 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr16_+_89988259 0.058 ENST00000554444.1
ENST00000556565.1
TUBB3

Tubulin beta-3 chain

chr19_+_7953417 0.058 ENST00000600345.1
ENST00000598224.1
LRRC8E

leucine rich repeat containing 8 family, member E

chr1_-_157108266 0.057 ENST00000326786.4
ETV3
ets variant 3
chrX_+_133371077 0.057 ENST00000517294.1
ENST00000370809.4
CCDC160

coiled-coil domain containing 160

chr19_-_18995029 0.057 ENST00000596048.1
CERS1
ceramide synthase 1
chr21_+_30671690 0.056 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr18_-_49557 0.056 ENST00000308911.6
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr16_+_30968615 0.056 ENST00000262519.8
SETD1A
SET domain containing 1A
chr7_-_102985035 0.055 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr3_+_11267691 0.055 ENST00000413416.1
HRH1
histamine receptor H1
chr10_+_88428206 0.055 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chr11_-_6191638 0.053 ENST00000530810.1
OR52B2
olfactory receptor, family 52, subfamily B, member 2
chrY_+_15016725 0.052 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr18_-_268019 0.051 ENST00000261600.6
THOC1
THO complex 1
chr17_-_18161870 0.049 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
FLII



flightless I homolog (Drosophila)



chr21_+_30671189 0.048 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr16_-_31161380 0.048 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36


protease, serine, 36


chr1_-_52344416 0.048 ENST00000544028.1
NRD1
nardilysin (N-arginine dibasic convertase)
chr10_+_85899196 0.048 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr17_-_42345487 0.048 ENST00000262418.6
SLC4A1
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr19_-_51587502 0.048 ENST00000156499.2
ENST00000391802.1
KLK14

kallikrein-related peptidase 14

chr2_+_87754989 0.048 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152



long intergenic non-protein coding RNA 152



chr6_-_84140757 0.047 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1


malic enzyme 1, NADP(+)-dependent, cytosolic



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.4 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.8 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.2 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.4 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 1.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.2 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation