Motif ID: ALX3

Z-value: 0.835


Transcription factors associated with ALX3:

Gene SymbolEntrez IDGene Name
ALX3 ENSG00000156150.6 ALX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ALX3hg19_v2_chr1_-_110613276_1106133220.049.2e-01Click!


Activity profile for motif ALX3.

activity profile for motif ALX3


Sorted Z-values histogram for motif ALX3

Sorted Z-values for motif ALX3



Network of associatons between targets according to the STRING database.



First level regulatory network of ALX3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_25865159 1.738 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr12_-_10022735 1.299 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr9_+_470288 1.174 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr1_+_81771806 1.020 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr14_-_54425475 1.013 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr10_+_5135981 0.999 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr1_+_28261533 0.981 ENST00000411604.1
ENST00000373888.4
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr4_+_86525299 0.883 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr1_+_28261492 0.871 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr15_+_94899183 0.827 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr7_-_121944491 0.775 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr2_+_210518057 0.774 ENST00000452717.1
MAP2
microtubule-associated protein 2
chr10_+_6821545 0.744 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr7_+_117864708 0.736 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ANKRD7



ankyrin repeat domain 7



chr10_+_91152303 0.713 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr2_+_210517895 0.706 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr1_+_28261621 0.670 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_+_5710919 0.644 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr8_+_92261516 0.637 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr14_-_54423529 0.630 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr14_+_39944025 0.606 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr10_+_6779326 0.584 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr10_+_24755416 0.581 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr4_-_110736505 0.549 ENST00000609440.1
RP11-602N24.3
RP11-602N24.3
chr4_-_36245561 0.543 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_+_37455536 0.531 ENST00000381980.4
ENST00000508175.1
C4orf19

chromosome 4 open reading frame 19

chr2_+_191221240 0.514 ENST00000409027.1
ENST00000458193.1
INPP1

inositol polyphosphate-1-phosphatase

chr19_-_44388116 0.460 ENST00000587539.1
ZNF404
zinc finger protein 404
chr9_+_12775011 0.454 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr16_-_55866997 0.442 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr3_+_43020773 0.414 ENST00000488863.1
FAM198A
family with sequence similarity 198, member A
chr11_-_121986923 0.379 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chrX_+_77166172 0.373 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr11_+_101918153 0.366 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr2_-_231860596 0.347 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2






SPATA3 antisense RNA 1 (head to head)






chr7_-_92777606 0.336 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr16_-_28937027 0.336 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chrX_-_13835147 0.335 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr10_-_105845536 0.334 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr11_+_71900703 0.330 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr5_+_140579162 0.325 ENST00000536699.1
ENST00000354757.3
PCDHB11

protocadherin beta 11

chr11_+_71900572 0.314 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr6_+_28317685 0.311 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr4_-_48116540 0.310 ENST00000506073.1
TXK
TXK tyrosine kinase
chr5_+_150639360 0.297 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr8_-_30670384 0.288 ENST00000221138.4
ENST00000518243.1
PPP2CB

protein phosphatase 2, catalytic subunit, beta isozyme

chr4_-_74486217 0.286 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr8_-_623547 0.286 ENST00000522893.1
ERICH1
glutamate-rich 1
chrX_+_3189861 0.283 ENST00000457435.1
ENST00000420429.2
CXorf28

chromosome X open reading frame 28

chr12_-_10978957 0.280 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr21_-_22175341 0.278 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
LINC00320



long intergenic non-protein coding RNA 320



chr2_+_102615416 0.273 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr4_+_147145709 0.272 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr4_+_86699834 0.265 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr3_+_183853052 0.260 ENST00000273783.3
ENST00000432569.1
ENST00000444495.1
EIF2B5


eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa


chr4_-_74486109 0.258 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr12_+_16500037 0.254 ENST00000536371.1
ENST00000010404.2
MGST1

microsomal glutathione S-transferase 1

chr4_+_66536248 0.253 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr13_+_24144796 0.250 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr12_+_16500599 0.249 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1



microsomal glutathione S-transferase 1



chr11_+_327171 0.244 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12


RP11-326C3.12


chr7_+_133812052 0.244 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr5_-_94417314 0.242 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_-_94417339 0.239 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chr5_-_94417186 0.232 ENST00000312216.8
ENST00000512425.1
MCTP1

multiple C2 domains, transmembrane 1

chr7_+_37723420 0.230 ENST00000476620.1
EPDR1
ependymin related 1
chr17_+_35851570 0.229 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr2_+_217524323 0.227 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr6_+_26402517 0.224 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr5_-_94417562 0.222 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr10_+_90660832 0.218 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr12_+_16500571 0.218 ENST00000543076.1
ENST00000396210.3
MGST1

microsomal glutathione S-transferase 1

chr10_-_90611566 0.210 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr17_-_295730 0.208 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr13_+_78315348 0.200 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr2_-_101925055 0.197 ENST00000295317.3
RNF149
ring finger protein 149
chr6_+_26402465 0.196 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr19_-_58864848 0.195 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr1_-_31666767 0.191 ENST00000530145.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr7_-_87342564 0.190 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr6_+_26440700 0.187 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr1_+_62439037 0.185 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr16_+_31724618 0.180 ENST00000530881.1
ENST00000529515.1
ZNF720

zinc finger protein 720

chr4_+_80584903 0.175 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr14_+_39736582 0.175 ENST00000556148.1
ENST00000348007.3
CTAGE5

CTAGE family, member 5

chr8_+_30244580 0.175 ENST00000523115.1
ENST00000519647.1
RBPMS

RNA binding protein with multiple splicing

chr8_-_29605625 0.172 ENST00000506121.3
LINC00589
long intergenic non-protein coding RNA 589
chr6_+_26183958 0.171 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr13_+_78315295 0.167 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr6_+_160693591 0.165 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr12_-_23737534 0.163 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr5_-_53115506 0.160 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1

CTD-2081C10.1

chr2_-_166060382 0.159 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr10_-_28571015 0.158 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr4_-_66536196 0.152 ENST00000511294.1
EPHA5
EPH receptor A5
chr22_+_42834029 0.151 ENST00000428765.1
CTA-126B4.7
CTA-126B4.7
chr16_-_28621353 0.149 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr7_+_156433573 0.142 ENST00000311822.8
RNF32
ring finger protein 32
chr16_-_28621298 0.140 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_74486347 0.136 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_34204642 0.134 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr2_-_225811747 0.133 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr4_-_85654615 0.131 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr19_-_14064114 0.128 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1



podocan-like 1



chr6_+_26087646 0.128 ENST00000309234.6
HFE
hemochromatosis
chr6_-_36515177 0.127 ENST00000229812.7
STK38
serine/threonine kinase 38
chr17_+_40610862 0.127 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1








ATPase, H+ transporting, lysosomal V0 subunit a1








chr1_+_225600404 0.127 ENST00000366845.2
AC092811.1
AC092811.1
chr5_+_115177178 0.126 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr16_-_30122717 0.126 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr4_+_95128748 0.121 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr15_-_98417780 0.116 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr5_+_55149150 0.114 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr4_+_169633310 0.114 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr5_+_140557371 0.113 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr3_+_195447738 0.111 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20


mucin 20, cell surface associated


chr19_+_49199209 0.111 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2


fucosyltransferase 2 (secretor status included)


chr11_+_118398178 0.107 ENST00000302783.4
ENST00000539546.1
TTC36

tetratricopeptide repeat domain 36

chr4_+_26324474 0.107 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_66536057 0.106 ENST00000273854.3
EPHA5
EPH receptor A5
chr2_-_152118276 0.105 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr4_+_110736659 0.104 ENST00000394631.3
ENST00000226796.6
GAR1

GAR1 ribonucleoprotein

chr6_+_26087509 0.104 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr12_+_131438496 0.101 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr12_-_10282836 0.101 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A


C-type lectin domain family 7, member A


chr12_+_59194154 0.100 ENST00000548969.1
RP11-362K2.2
Protein LOC100506869
chr6_-_52109335 0.099 ENST00000336123.4
IL17F
interleukin 17F
chr4_-_103749205 0.098 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_+_81575281 0.097 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr2_+_166095898 0.097 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A


sodium channel, voltage-gated, type II, alpha subunit


chr12_+_131438443 0.095 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr16_-_28608424 0.094 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_+_72088376 0.093 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP








HPR
haptoglobin








haptoglobin-related protein
chr5_+_96840389 0.091 ENST00000504012.1
RP11-1E3.1
RP11-1E3.1
chr7_-_2883650 0.091 ENST00000544127.1
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr2_-_198540719 0.087 ENST00000295049.4
RFTN2
raftlin family member 2
chr9_+_124329336 0.086 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr4_+_88720698 0.086 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr11_-_63376013 0.084 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr5_+_102200948 0.083 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM


peptidylglycine alpha-amidating monooxygenase


chr4_-_103749179 0.083 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr17_-_64225508 0.083 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_187371440 0.081 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr16_+_15489603 0.081 ENST00000287594.7
ENST00000568766.1
MPV17L
RP11-1021N1.1
MPV17 mitochondrial membrane protein-like
Uncharacterized protein
chr10_+_695888 0.081 ENST00000441152.2
PRR26
proline rich 26
chr5_+_140762268 0.080 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr4_-_103749105 0.079 ENST00000394801.4
ENST00000394804.2
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr7_-_2883928 0.078 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr2_-_205099700 0.077 ENST00000419860.1
AC009498.1
AC009498.1
chr12_+_64798826 0.074 ENST00000540203.1
XPOT
exportin, tRNA
chr8_+_55528627 0.073 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr4_+_89206076 0.073 ENST00000500009.2
RP11-10L7.1
RP11-10L7.1
chr2_+_68962014 0.072 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr17_-_4938712 0.071 ENST00000254853.5
ENST00000424747.1
SLC52A1

solute carrier family 52 (riboflavin transporter), member 1

chr1_+_207226574 0.069 ENST00000367080.3
ENST00000367079.2
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr4_-_103749313 0.069 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_-_58207646 0.069 ENST00000302572.2
OR5B12
olfactory receptor, family 5, subfamily B, member 12
chr2_+_90273679 0.068 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr20_-_50418972 0.067 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr6_-_32095968 0.064 ENST00000375203.3
ENST00000375201.4
ATF6B

activating transcription factor 6 beta

chr2_+_103089756 0.064 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr10_+_696000 0.063 ENST00000381489.5
PRR26
proline rich 26
chrX_+_84258832 0.063 ENST00000373173.2
APOOL
apolipoprotein O-like
chr16_-_28634874 0.061 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr2_+_145425534 0.060 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
TEX41













testis expressed 41 (non-protein coding)













chr14_+_55493920 0.059 ENST00000395472.2
ENST00000555846.1
SOCS4

suppressor of cytokine signaling 4

chr4_-_103748880 0.058 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr11_+_100784231 0.058 ENST00000531183.1
ARHGAP42
Rho GTPase activating protein 42
chr9_-_115095229 0.057 ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chrX_+_77154935 0.056 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr1_-_24126023 0.056 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr16_+_31724552 0.055 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720




zinc finger protein 720




chr4_-_46126093 0.055 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr6_+_55192267 0.055 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr6_+_161123270 0.054 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr3_-_191000172 0.054 ENST00000427544.2
UTS2B
urotensin 2B
chr20_+_33134619 0.053 ENST00000374837.3
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr20_-_43133491 0.052 ENST00000411544.1
SERINC3
serine incorporator 3
chr12_+_116955659 0.052 ENST00000552992.1
RP11-148B3.1
RP11-148B3.1
chr5_-_98262240 0.052 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr21_-_22175450 0.052 ENST00000435279.2
LINC00320
long intergenic non-protein coding RNA 320
chr4_+_26344754 0.051 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr2_+_113299990 0.051 ENST00000537335.1
ENST00000417433.2
POLR1B

polymerase (RNA) I polypeptide B, 128kDa

chr7_-_149158187 0.050 ENST00000247930.4
ZNF777
zinc finger protein 777
chr11_+_57480046 0.050 ENST00000378312.4
ENST00000278422.4
TMX2

thioredoxin-related transmembrane protein 2

chr8_-_93978216 0.049 ENST00000517751.1
ENST00000524107.1
TRIQK

triple QxxK/R motif containing

chr14_-_78083112 0.048 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr19_+_47421933 0.048 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr4_-_139051839 0.048 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
LINC00616


long intergenic non-protein coding RNA 616


chr10_+_35894338 0.048 ENST00000321660.1
GJD4
gap junction protein, delta 4, 40.1kDa
chr2_+_102953608 0.047 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr6_+_37897735 0.045 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr4_-_120243545 0.045 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr3_-_160823158 0.043 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1


beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)


chr8_-_91095099 0.043 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr2_-_43266680 0.043 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2


AC016735.2


chr1_-_24126051 0.043 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr2_+_68961905 0.041 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr4_+_158493642 0.041 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1


RP11-364P22.1


chr14_+_55494323 0.040 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.0 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.3 1.6 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 0.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.2 0.6 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.2 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 2.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.7 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.6 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.1 0.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0072025 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0045550 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.2 0.6 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 2.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.4 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 1.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.7 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)