Motif ID: AGCAGCA

Z-value: 0.424


Mature miRNA associated with seed AGCAGCA:

NamemiRBase Accession
hsa-miR-15a-5p MIMAT0000068
hsa-miR-15b-5p MIMAT0000417
hsa-miR-16-5p MIMAT0000069
hsa-miR-195-5p MIMAT0000461
hsa-miR-424-5p MIMAT0001341
hsa-miR-497-5p MIMAT0002820
hsa-miR-6838-5p MIMAT0027578



Activity profile for motif AGCAGCA.

activity profile for motif AGCAGCA


Sorted Z-values histogram for motif AGCAGCA

Sorted Z-values for motif AGCAGCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_10458982 0.551 ENST00000326756.3
ZNF518B
zinc finger protein 518B
chr9_+_118916082 0.504 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_+_470288 0.494 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr4_-_25864581 0.464 ENST00000399878.3
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr7_-_95225768 0.418 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr7_-_82073109 0.380 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr7_+_155250824 0.344 ENST00000297375.4
EN2
engrailed homeobox 2
chr4_+_15004165 0.319 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2


cytoplasmic polyadenylation element binding protein 2


chr20_+_10199468 0.306 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr9_+_12775011 0.283 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr15_+_41245160 0.269 ENST00000444189.2
ENST00000446533.3
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr18_-_30050395 0.259 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr1_+_110453203 0.253 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1


colony stimulating factor 1 (macrophage)


chr9_-_27529726 0.249 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr1_-_57045228 0.243 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr7_+_95401851 0.242 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chrX_+_106163626 0.242 ENST00000336803.1
CLDN2
claudin 2
chr2_+_42275153 0.236 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr3_+_173116225 0.229 ENST00000457714.1
NLGN1
neuroligin 1
chr4_-_55991752 0.212 ENST00000263923.4
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr4_+_126237554 0.210 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr16_-_68269971 0.205 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr4_-_168155730 0.200 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr5_+_32711419 0.199 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr3_+_171758344 0.184 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr1_-_22263790 0.184 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr4_+_72204755 0.181 ENST00000512686.1
ENST00000340595.3
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chr2_-_219925189 0.180 ENST00000295731.6
IHH
indian hedgehog
chr2_+_203879568 0.174 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr1_+_224803995 0.172 ENST00000272133.3
CNIH3
cornichon family AMPA receptor auxiliary protein 3
chr7_-_103629963 0.172 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr10_+_52751010 0.171 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr8_-_72268889 0.171 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr17_-_29624343 0.170 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr11_+_72929319 0.167 ENST00000393597.2
ENST00000311131.2
P2RY2

purinergic receptor P2Y, G-protein coupled, 2

chr2_+_28615669 0.166 ENST00000379619.1
ENST00000264716.4
FOSL2

FOS-like antigen 2

chr6_-_75915757 0.165 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chrX_+_10124977 0.162 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr1_+_82266053 0.162 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr8_-_82024290 0.162 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr17_-_6459768 0.160 ENST00000421306.3
PITPNM3
PITPNM family member 3
chr4_+_77356248 0.157 ENST00000296043.6
SHROOM3
shroom family member 3
chr13_+_58206655 0.156 ENST00000377918.3
PCDH17
protocadherin 17
chr3_-_178790057 0.152 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr1_-_6321035 0.151 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr19_+_16771936 0.150 ENST00000187762.2
ENST00000599479.1
TMEM38A

transmembrane protein 38A

chr1_+_78470530 0.143 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_+_114055052 0.143 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr6_-_94129244 0.142 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr3_+_183903811 0.141 ENST00000429586.2
ENST00000292808.5
ABCF3

ATP-binding cassette, sub-family F (GCN20), member 3

chr5_+_133861790 0.140 ENST00000395003.1
PHF15
jade family PHD finger 2
chr1_-_232697304 0.137 ENST00000366630.1
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_+_20255123 0.134 ENST00000504154.1
ENST00000273739.5
SLIT2

slit homolog 2 (Drosophila)

chrX_+_49687216 0.133 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr1_+_180199393 0.131 ENST00000263726.2
LHX4
LIM homeobox 4
chr1_-_92351769 0.130 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr11_-_82782861 0.125 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30




RAB30, member RAS oncogene family




chr5_+_52285144 0.123 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr2_+_148602058 0.123 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A


activin A receptor, type IIA


chr8_+_37594130 0.122 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2


ER lipid raft associated 2


chr7_-_14029515 0.121 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1


ets variant 1


chr9_+_92219919 0.121 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr17_-_295730 0.120 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr12_-_26278030 0.119 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr3_+_187930719 0.119 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_+_112812778 0.119 ENST00000283206.4
TMEM87B
transmembrane protein 87B
chr1_+_10271674 0.118 ENST00000377086.1
KIF1B
kinesin family member 1B
chr1_-_201438282 0.118 ENST00000367311.3
ENST00000367309.1
PHLDA3

pleckstrin homology-like domain, family A, member 3

chr8_+_17354587 0.117 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr2_+_204192942 0.115 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chrX_+_13707235 0.114 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr3_-_182698381 0.114 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr2_-_227664474 0.109 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr19_-_44285401 0.107 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr4_+_128703295 0.107 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr8_-_75233563 0.107 ENST00000342232.4
JPH1
junctophilin 1
chr13_+_108921977 0.105 ENST00000430559.1
ENST00000375887.4
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr1_-_9970227 0.105 ENST00000377263.1
CTNNBIP1
catenin, beta interacting protein 1
chr1_+_12040238 0.104 ENST00000444836.1
ENST00000235329.5
MFN2

mitofusin 2

chr17_+_28705921 0.104 ENST00000225719.4
CPD
carboxypeptidase D
chr20_+_43374421 0.104 ENST00000372861.3
KCNK15
potassium channel, subfamily K, member 15
chrX_+_49126294 0.104 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F



protein phosphatase 1, regulatory subunit 3F



chr3_-_56502375 0.102 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr1_+_27561007 0.102 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr4_+_108745711 0.101 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr12_-_63328817 0.099 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_-_41909561 0.099 ENST00000372991.4
CCND3
cyclin D3
chr17_+_67410832 0.099 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_-_76944621 0.099 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_+_43737939 0.098 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr20_-_50159198 0.098 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2


chr13_-_107187462 0.096 ENST00000245323.4
EFNB2
ephrin-B2
chr1_+_64239657 0.093 ENST00000371080.1
ENST00000371079.1
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr5_-_141704566 0.091 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr5_+_175792459 0.091 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr2_+_149632783 0.091 ENST00000435030.1
KIF5C
kinesin family member 5C
chrX_-_109561294 0.091 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr2_+_54951679 0.090 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr6_+_18387570 0.090 ENST00000259939.3
RNF144B
ring finger protein 144B
chr3_-_171178157 0.090 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr9_-_112083229 0.089 ENST00000374566.3
ENST00000374557.4
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chrX_+_77166172 0.089 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr14_+_32546485 0.088 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5


Rho GTPase activating protein 5


chr11_+_48002076 0.088 ENST00000418331.2
ENST00000440289.2
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr3_+_126707437 0.087 ENST00000393409.2
ENST00000251772.4
PLXNA1

plexin A1

chr17_+_46125707 0.087 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1



nuclear factor, erythroid 2-like 1



chr11_+_77300669 0.086 ENST00000313578.3
AQP11
aquaporin 11
chrX_-_77914825 0.086 ENST00000321110.1
ZCCHC5
zinc finger, CCHC domain containing 5
chr2_+_120517174 0.086 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr1_+_206680879 0.086 ENST00000355294.4
ENST00000367117.3
RASSF5

Ras association (RalGDS/AF-6) domain family member 5

chr3_-_176914238 0.085 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chrX_+_72783026 0.085 ENST00000373504.6
ENST00000373502.5
CHIC1

cysteine-rich hydrophobic domain 1

chr8_-_42397037 0.083 ENST00000342228.3
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr6_-_97285336 0.083 ENST00000229955.3
ENST00000417980.1
GPR63

G protein-coupled receptor 63

chr8_-_81787006 0.083 ENST00000327835.3
ZNF704
zinc finger protein 704
chr3_-_145968923 0.082 ENST00000493382.1
ENST00000354952.2
ENST00000383083.2
PLSCR4


phospholipid scramblase 4


chr2_-_166930131 0.082 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr8_+_38614807 0.081 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr21_+_35445827 0.080 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr16_+_84853580 0.078 ENST00000262424.5
ENST00000566151.1
ENST00000567845.1
ENST00000564567.1
ENST00000569090.1
CRISPLD2




cysteine-rich secretory protein LCCL domain containing 2




chrX_-_54384425 0.078 ENST00000375169.3
ENST00000354646.2
WNK3

WNK lysine deficient protein kinase 3

chr11_+_6411636 0.077 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr4_+_26585538 0.077 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr11_-_34379546 0.077 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chrX_+_21392873 0.076 ENST00000379510.3
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr1_-_150979333 0.076 ENST00000312210.5
FAM63A
family with sequence similarity 63, member A
chr5_+_148206156 0.075 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr5_-_66492562 0.074 ENST00000256447.4
CD180
CD180 molecule
chr8_+_25316489 0.074 ENST00000330560.3
CDCA2
cell division cycle associated 2
chr4_+_166794383 0.073 ENST00000061240.2
ENST00000507499.1
TLL1

tolloid-like 1

chr2_+_198365122 0.073 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr8_+_21777159 0.073 ENST00000434536.1
ENST00000252512.9
XPO7

exportin 7

chr12_-_39837192 0.072 ENST00000361961.3
ENST00000395670.3
KIF21A

kinesin family member 21A

chr2_+_198380289 0.071 ENST00000233892.4
ENST00000409916.1
MOB4

MOB family member 4, phocein

chr12_+_74931551 0.070 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr10_-_28034989 0.070 ENST00000375790.5
MKX
mohawk homeobox
chr19_-_40324255 0.070 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr5_+_102201430 0.069 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr10_+_47083454 0.067 ENST00000374312.1
NPY4R
neuropeptide Y receptor Y4
chr6_+_32121218 0.067 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2


palmitoyl-protein thioesterase 2


chr4_+_174089904 0.067 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_+_78245303 0.066 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr9_+_19049372 0.066 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr1_+_15853308 0.065 ENST00000375838.1
ENST00000375847.3
ENST00000375849.1
DNAJC16


DnaJ (Hsp40) homolog, subfamily C, member 16


chr14_-_105420241 0.065 ENST00000557457.1
AHNAK2
AHNAK nucleoprotein 2
chr18_+_29598335 0.065 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr4_-_100815525 0.064 ENST00000226522.8
ENST00000499666.2
LAMTOR3

late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

chr8_-_67525473 0.064 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr12_-_51477333 0.064 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
CSRNP2



cysteine-serine-rich nuclear protein 2



chr5_-_141257954 0.063 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1



protocadherin 1



chr8_+_22857048 0.063 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr5_+_127419449 0.063 ENST00000262461.2
ENST00000343225.4
SLC12A2

solute carrier family 12 (sodium/potassium/chloride transporter), member 2

chr21_-_44846999 0.063 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr1_+_28586006 0.063 ENST00000253063.3
SESN2
sestrin 2
chr9_+_77112244 0.063 ENST00000376896.3
RORB
RAR-related orphan receptor B
chr2_-_122407097 0.063 ENST00000409078.3
CLASP1
cytoplasmic linker associated protein 1
chr5_+_67511524 0.062 ENST00000521381.1
ENST00000521657.1
PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

chr8_-_37756972 0.062 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1


RAB11 family interacting protein 1 (class I)


chr5_-_132299313 0.062 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr1_-_22469459 0.061 ENST00000290167.6
WNT4
wingless-type MMTV integration site family, member 4
chr8_-_38326139 0.061 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
FGFR1


fibroblast growth factor receptor 1


chr16_+_50775948 0.061 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD


cylindromatosis (turban tumor syndrome)


chr18_+_60190226 0.060 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr7_+_1570322 0.060 ENST00000343242.4
MAFK
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr14_-_23822080 0.060 ENST00000397267.1
ENST00000354772.3
SLC22A17

solute carrier family 22, member 17

chr2_-_183903133 0.059 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr2_+_206547215 0.059 ENST00000360409.3
ENST00000540178.1
ENST00000540841.1
ENST00000355117.4
ENST00000450507.1
ENST00000417189.1
NRP2





neuropilin 2





chr2_-_172017343 0.058 ENST00000431350.2
ENST00000360843.3
TLK1

tousled-like kinase 1

chr1_-_115212696 0.058 ENST00000393276.3
ENST00000393277.1
DENND2C

DENN/MADD domain containing 2C

chr9_+_35749203 0.058 ENST00000456972.2
ENST00000378078.4
RGP1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr14_+_23775971 0.058 ENST00000250405.5
BCL2L2
BCL2-like 2
chr3_-_170626418 0.057 ENST00000474096.1
ENST00000295822.2
EIF5A2

eukaryotic translation initiation factor 5A2

chr17_+_45608430 0.057 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr17_-_35969409 0.056 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG







synergin, gamma







chr4_+_123747834 0.056 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr1_-_36022979 0.056 ENST00000469892.1
ENST00000325722.3
KIAA0319L

KIAA0319-like

chrX_+_102192200 0.056 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr1_-_47069955 0.056 ENST00000341183.5
ENST00000496619.1
MKNK1

MAP kinase interacting serine/threonine kinase 1

chr11_-_74109422 0.055 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr1_-_208417620 0.055 ENST00000367033.3
PLXNA2
plexin A2
chr8_+_120885949 0.055 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr8_+_42128812 0.054 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
IKBKB




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta




chr6_+_30539153 0.054 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1




ATP-binding cassette, sub-family F (GCN20), member 1




chr20_+_3776371 0.054 ENST00000245960.5
CDC25B
cell division cycle 25B
chr19_-_7293942 0.054 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr5_+_139944024 0.054 ENST00000323146.3
SLC35A4
solute carrier family 35, member A4
chr2_+_166095898 0.054 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A


sodium channel, voltage-gated, type II, alpha subunit


chr5_+_65440032 0.053 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr2_+_110371905 0.053 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr5_+_140345820 0.053 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr4_+_160188889 0.052 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr5_+_157170703 0.052 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr8_+_22102626 0.051 ENST00000519237.1
ENST00000397802.4
POLR3D

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa

chrX_-_41782249 0.051 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK




calcium/calmodulin-dependent serine protein kinase (MAGUK family)




chr3_-_197476560 0.051 ENST00000273582.5
KIAA0226
KIAA0226
chr14_-_39901618 0.051 ENST00000554932.1
ENST00000298097.7
FBXO33

F-box protein 33

chr1_+_2160134 0.051 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr8_+_23430157 0.051 ENST00000399967.3
FP15737
FP15737
chr5_+_125758813 0.051 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr20_+_49348081 0.051 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.3 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.4 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.1 0.2 GO:1990709 presynaptic active zone organization(GO:1990709)
0.1 0.3 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.3 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0048372 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.2 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.0 0.5 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.0 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:0044335 external genitalia morphogenesis(GO:0035261) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.0 0.0 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:0060066 oviduct development(GO:0060066)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.0 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0004994 somatostatin receptor activity(GO:0004994)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex