Motif ID: AAUCUCA

Z-value: 0.115


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a-5p MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_32452357 0.090 ENST00000379079.2
ENST00000530998.1
 WT1

Wilms tumor 1

chr14_+_62037287 0.067 ENST00000556569.1
 RP11-47I22.3
Uncharacterized protein
chr18_+_59992527 0.063 ENST00000586569.1
 TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr5_+_122424816 0.051 ENST00000407847.4
 PRDM6
PR domain containing 6
chr10_+_11206925 0.040 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
 CELF2


CUGBP, Elav-like family member 2


chr2_-_172967621 0.039 ENST00000234198.4
ENST00000466293.2
 DLX2

distal-less homeobox 2

chr4_-_105416039 0.036 ENST00000394767.2
 CXXC4
CXXC finger protein 4
chr3_+_126707437 0.033 ENST00000393409.2
ENST00000251772.4
 PLXNA1

plexin A1

chr5_-_178054105 0.022 ENST00000316308.4
 CLK4
CDC-like kinase 4
chr17_+_64298944 0.022 ENST00000413366.3
 PRKCA
protein kinase C, alpha
chrX_+_23352133 0.013 ENST00000379361.4
 PTCHD1
patched domain containing 1
chr1_-_67519782 0.012 ENST00000235345.5
 SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr2_+_231921574 0.012 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
 PSMD1



proteasome (prosome, macropain) 26S subunit, non-ATPase, 1



chr20_-_524455 0.011 ENST00000349736.5
ENST00000217244.3
 CSNK2A1

casein kinase 2, alpha 1 polypeptide

chr6_+_42749759 0.011 ENST00000314073.5
 GLTSCR1L
GLTSCR1-like
chr17_-_73975444 0.010 ENST00000293217.5
ENST00000537812.1
 ACOX1

acyl-CoA oxidase 1, palmitoyl

chr4_+_3076388 0.010 ENST00000355072.5
 HTT
huntingtin
chr2_-_242212227 0.009 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
 HDLBP








high density lipoprotein binding protein








chr4_+_99916765 0.008 ENST00000296411.6
 METAP1
methionyl aminopeptidase 1
chr1_-_53793584 0.007 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
 LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chrX_+_122993827 0.006 ENST00000371199.3
 XIAP
X-linked inhibitor of apoptosis
chr7_+_12250886 0.005 ENST00000444443.1
ENST00000396667.3
 TMEM106B

transmembrane protein 106B

chr9_-_20622478 0.003 ENST00000355930.6
ENST00000380338.4
 MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr7_-_139876812 0.002 ENST00000397560.2
 JHDM1D
lysine (K)-specific demethylase 7A
chr11_+_111945011 0.001 ENST00000532163.1
ENST00000280352.9
ENST00000530104.1
ENST00000526879.1
ENST00000393047.3
ENST00000525785.1
 C11orf57





chromosome 11 open reading frame 57






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072299 visceral serous pericardium development(GO:0061032) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0071812 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.0 0.0 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)