Motif ID: AAGGCAC

Z-value: 0.342


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124-3p.1 MIMAT0000422



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_+_36041688 0.493 ENST00000360731.3
ENST00000349499.2
CLIC6

chloride intracellular channel 6

chr9_+_470288 0.459 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr7_-_124405681 0.342 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chrX_+_105937068 0.334 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr18_-_45663666 0.320 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr9_+_118916082 0.317 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr7_+_155250824 0.315 ENST00000297375.4
EN2
engrailed homeobox 2
chr2_+_65216462 0.312 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_-_82073109 0.308 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr1_+_31885963 0.296 ENST00000373709.3
SERINC2
serine incorporator 2
chr11_-_70507901 0.269 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2


SH3 and multiple ankyrin repeat domains 2


chr11_+_121322832 0.229 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_-_230933709 0.226 ENST00000436869.1
ENST00000295190.4
SLC16A14

solute carrier family 16, member 14

chr3_-_13461807 0.219 ENST00000254508.5
NUP210
nucleoporin 210kDa
chr6_-_169654139 0.215 ENST00000366787.3
THBS2
thrombospondin 2
chr17_+_63133587 0.199 ENST00000449996.3
ENST00000262406.9
RGS9

regulator of G-protein signaling 9

chr14_+_71108460 0.197 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr14_-_105635090 0.193 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr20_-_10654639 0.187 ENST00000254958.5
JAG1
jagged 1
chr18_+_19749386 0.183 ENST00000269216.3
GATA6
GATA binding protein 6
chr11_-_68609377 0.177 ENST00000265641.5
ENST00000376618.2
CPT1A

carnitine palmitoyltransferase 1A (liver)

chr6_+_46097711 0.174 ENST00000321037.4
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr10_+_52751010 0.174 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chrX_+_153686614 0.172 ENST00000369682.3
PLXNA3
plexin A3
chr4_-_168155730 0.171 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr18_-_47721447 0.171 ENST00000285039.7
MYO5B
myosin VB
chr2_-_152955537 0.166 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr3_+_183353356 0.164 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24








kelch-like family member 24








chr11_-_94964354 0.164 ENST00000536441.1
SESN3
sestrin 3
chr8_-_60031762 0.163 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr12_-_53625958 0.161 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG



retinoic acid receptor, gamma



chr18_-_30050395 0.160 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr22_+_35936915 0.157 ENST00000216127.4
RASD2
RASD family, member 2
chr8_+_98881268 0.153 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2


matrilin 2


chr2_+_187558698 0.153 ENST00000304698.5
FAM171B
family with sequence similarity 171, member B
chr5_+_149340282 0.147 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr13_+_58206655 0.147 ENST00000377918.3
PCDH17
protocadherin 17
chr11_+_22214708 0.145 ENST00000324559.8
ANO5
anoctamin 5
chr5_-_115910630 0.145 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_-_208634287 0.140 ENST00000295417.3
FZD5
frizzled family receptor 5
chr17_-_202579 0.140 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL


rabphilin 3A-like (without C2 domains)


chr12_+_41086297 0.139 ENST00000551295.2
CNTN1
contactin 1
chr8_-_494824 0.139 ENST00000427263.2
ENST00000324079.6
TDRP

testis development related protein

chr6_-_75915757 0.138 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr1_-_6321035 0.138 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr4_+_108745711 0.137 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr14_+_23067146 0.133 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr4_-_149365827 0.131 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr3_-_178790057 0.130 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr3_+_69812877 0.129 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr2_+_241375069 0.127 ENST00000264039.2
GPC1
glypican 1
chr10_+_72432559 0.125 ENST00000373208.1
ENST00000373207.1
ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14

chr2_-_204400113 0.120 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr2_+_191045562 0.119 ENST00000340623.4
C2orf88
chromosome 2 open reading frame 88
chr4_+_95679072 0.118 ENST00000515059.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr6_+_28317685 0.118 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr17_+_67410832 0.117 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr8_+_17013515 0.115 ENST00000262096.8
ZDHHC2
zinc finger, DHHC-type containing 2
chr5_+_109025067 0.115 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr1_-_16482554 0.114 ENST00000358432.5
EPHA2
EPH receptor A2
chr1_-_204329013 0.114 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr3_-_24536253 0.112 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB





thyroid hormone receptor, beta





chr20_-_18038521 0.112 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr10_+_71211212 0.111 ENST00000373290.2
TSPAN15
tetraspanin 15
chr8_-_63998590 0.110 ENST00000260116.4
TTPA
tocopherol (alpha) transfer protein
chr3_-_185216766 0.110 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr2_+_28615669 0.110 ENST00000379619.1
ENST00000264716.4
FOSL2

FOS-like antigen 2

chr3_+_180630090 0.109 ENST00000357559.4
ENST00000305586.7
FXR1

fragile X mental retardation, autosomal homolog 1

chr2_-_172967621 0.108 ENST00000234198.4
ENST00000466293.2
DLX2

distal-less homeobox 2

chr9_-_91793675 0.107 ENST00000375835.4
ENST00000375830.1
SHC3

SHC (Src homology 2 domain containing) transforming protein 3

chr8_-_72268889 0.107 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr2_+_137523086 0.107 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr8_-_37756972 0.107 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1


RAB11 family interacting protein 1 (class I)


chr1_-_16678914 0.107 ENST00000375592.3
FBXO42
F-box protein 42
chr6_+_138483058 0.107 ENST00000251691.4
KIAA1244
KIAA1244
chr3_-_182698381 0.106 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr3_+_187930719 0.105 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_-_124080203 0.105 ENST00000504926.1
ZNF608
zinc finger protein 608
chr7_+_29874341 0.105 ENST00000409290.1
ENST00000242140.5
WIPF3

WAS/WASL interacting protein family, member 3

chr8_-_29120580 0.105 ENST00000524189.1
KIF13B
kinesin family member 13B
chr2_+_24272543 0.104 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr20_+_8112824 0.104 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr1_-_10003372 0.103 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC


leucine zipper and CTNNBIP1 domain containing


chr7_+_17338239 0.103 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr20_-_50159198 0.102 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2


chr4_+_124320665 0.102 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr8_-_20161466 0.101 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr2_+_112812778 0.100 ENST00000283206.4
TMEM87B
transmembrane protein 87B
chr5_-_101632153 0.100 ENST00000310954.6
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr7_-_14029515 0.100 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1


ets variant 1


chr12_+_70760056 0.099 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr10_-_28034989 0.097 ENST00000375790.5
MKX
mohawk homeobox
chr3_+_178866199 0.095 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr6_+_7727030 0.093 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chrX_-_13956737 0.093 ENST00000454189.2
GPM6B
glycoprotein M6B
chr2_+_54951679 0.093 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chrX_+_9983602 0.090 ENST00000380861.4
WWC3
WWC family member 3
chrX_+_77166172 0.090 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr1_+_180199393 0.090 ENST00000263726.2
LHX4
LIM homeobox 4
chr21_+_35445827 0.090 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr5_-_100238956 0.090 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr7_-_100493482 0.090 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE



acetylcholinesterase (Yt blood group)



chr3_+_89156674 0.089 ENST00000336596.2
EPHA3
EPH receptor A3
chr1_+_7831323 0.089 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr4_+_41362796 0.089 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1




LIM and calponin homology domains 1




chr6_-_28220002 0.089 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr5_-_131563501 0.088 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2




prolyl 4-hydroxylase, alpha polypeptide II




chr17_+_28705921 0.088 ENST00000225719.4
CPD
carboxypeptidase D
chr3_+_183415558 0.088 ENST00000305135.5
YEATS2
YEATS domain containing 2
chr11_+_129685707 0.088 ENST00000281441.3
TMEM45B
transmembrane protein 45B
chr14_+_35515598 0.087 ENST00000280987.4
FAM177A1
family with sequence similarity 177, member A1
chr6_+_53659746 0.086 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr2_+_134877740 0.086 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr1_+_201979645 0.086 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr4_+_152330390 0.085 ENST00000503146.1
ENST00000435205.1
FAM160A1

family with sequence similarity 160, member A1

chr2_+_103236004 0.084 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr6_-_74363803 0.083 ENST00000355773.5
SLC17A5
solute carrier family 17 (acidic sugar transporter), member 5
chr1_+_57110972 0.082 ENST00000371244.4
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr7_-_158622210 0.082 ENST00000251527.5
ESYT2
extended synaptotagmin-like protein 2
chr9_+_2621798 0.081 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr9_-_110251836 0.081 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr11_+_76494253 0.079 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chrX_-_10645773 0.079 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr21_-_44846999 0.079 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr20_-_17662878 0.078 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr5_-_35230771 0.078 ENST00000342362.5
PRLR
prolactin receptor
chr8_+_17354587 0.078 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr22_+_25465786 0.078 ENST00000401395.1
KIAA1671
KIAA1671
chr8_-_75233563 0.078 ENST00000342232.4
JPH1
junctophilin 1
chr17_-_62207485 0.078 ENST00000433197.3
ERN1
endoplasmic reticulum to nucleus signaling 1
chr5_-_27038683 0.078 ENST00000511822.1
ENST00000231021.4
CDH9

cadherin 9, type 2 (T1-cadherin)

chr7_-_108096822 0.078 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM


neuronal cell adhesion molecule


chr1_+_214161272 0.076 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr8_-_145013711 0.076 ENST00000345136.3
PLEC
plectin
chr6_-_94129244 0.076 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr10_+_133918175 0.076 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr5_-_141257954 0.076 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1



protocadherin 1



chr8_+_32405728 0.075 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1




neuregulin 1




chr11_+_48002076 0.075 ENST00000418331.2
ENST00000440289.2
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr1_-_76076793 0.075 ENST00000370859.3
SLC44A5
solute carrier family 44, member 5
chr22_-_50946113 0.075 ENST00000216080.5
ENST00000474879.2
ENST00000380796.3
LMF2


lipase maturation factor 2


chr6_+_16238786 0.074 ENST00000259727.4
GMPR
guanosine monophosphate reductase
chr2_+_157291953 0.074 ENST00000310454.6
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr5_+_175792459 0.074 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr17_+_38375574 0.073 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr8_+_74206829 0.073 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr15_-_93199069 0.070 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr9_+_135037334 0.070 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2



netrin G2



chr1_+_160336851 0.069 ENST00000302101.5
NHLH1
nescient helix loop helix 1
chr8_-_9008206 0.069 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr8_+_38614807 0.068 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr6_-_41909561 0.068 ENST00000372991.4
CCND3
cyclin D3
chr4_-_2264015 0.067 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr1_-_101360331 0.067 ENST00000416479.1
ENST00000370113.3
EXTL2

exostosin-like glycosyltransferase 2

chr19_+_709101 0.067 ENST00000338448.5
PALM
paralemmin
chr6_-_36515177 0.067 ENST00000229812.7
STK38
serine/threonine kinase 38
chr18_+_32073253 0.066 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA


dystrobrevin, alpha


chr12_-_65146636 0.066 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr5_+_172068232 0.066 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B


neuralized E3 ubiquitin protein ligase 1B


chr4_+_76649797 0.065 ENST00000538159.1
ENST00000514213.2
USO1

USO1 vesicle transport factor

chr1_+_182992545 0.064 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr1_+_15943995 0.064 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr1_-_6295975 0.064 ENST00000343813.5
ENST00000362035.3
ICMT

isoprenylcysteine carboxyl methyltransferase

chr1_+_154975110 0.063 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr19_-_7990991 0.063 ENST00000318978.4
CTXN1
cortexin 1
chr15_-_45815005 0.063 ENST00000261867.4
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr11_-_87908600 0.063 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38


RAB38, member RAS oncogene family


chr12_+_133066137 0.063 ENST00000434748.2
FBRSL1
fibrosin-like 1
chr9_+_115913222 0.062 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr7_-_25019760 0.062 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chr15_-_49255632 0.062 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr2_+_113239710 0.061 ENST00000233336.6
TTL
tubulin tyrosine ligase
chr19_+_54371114 0.061 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM



myeloid-associated differentiation marker



chrX_-_54384425 0.061 ENST00000375169.3
ENST00000354646.2
WNK3

WNK lysine deficient protein kinase 3

chr4_-_100867864 0.060 ENST00000442697.2
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr9_+_101569944 0.060 ENST00000375011.3
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr5_-_132299313 0.059 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr1_+_206680879 0.059 ENST00000355294.4
ENST00000367117.3
RASSF5

Ras association (RalGDS/AF-6) domain family member 5

chr4_-_80994210 0.059 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr9_-_14314066 0.059 ENST00000397575.3
NFIB
nuclear factor I/B
chr6_+_44187242 0.058 ENST00000393844.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr4_+_7045042 0.058 ENST00000310074.7
ENST00000512388.1
TADA2B

transcriptional adaptor 2B

chr6_-_33756867 0.058 ENST00000293760.5
LEMD2
LEM domain containing 2
chr8_-_95961578 0.058 ENST00000448464.2
ENST00000342697.4
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr5_+_139944024 0.058 ENST00000323146.3
SLC35A4
solute carrier family 35, member A4
chr1_-_11986442 0.058 ENST00000376572.3
ENST00000376576.3
KIAA2013

KIAA2013

chr18_-_31803435 0.058 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
NOL4


nucleolar protein 4


chr5_+_148960931 0.057 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr10_+_112404132 0.057 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr14_+_103058948 0.056 ENST00000262241.6
RCOR1
REST corepressor 1
chr17_+_43224684 0.056 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr12_-_15942309 0.056 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8


epidermal growth factor receptor pathway substrate 8


chr6_-_154831779 0.056 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr1_-_179846928 0.056 ENST00000367612.3
ENST00000609928.1
TOR1AIP2

torsin A interacting protein 2

chr2_-_240322643 0.056 ENST00000345617.3
HDAC4
histone deacetylase 4
chr5_+_127419449 0.056 ENST00000262461.2
ENST00000343225.4
SLC12A2

solute carrier family 12 (sodium/potassium/chloride transporter), member 2

chrX_+_135067576 0.056 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
SLC9A6


solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6


chr1_-_21671968 0.055 ENST00000415912.2
ECE1
endothelin converting enzyme 1
chr13_+_88324870 0.055 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr2_+_200775971 0.055 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0 0.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0090427 regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.0 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.0 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0019230 proprioception(GO:0019230)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.0 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285)
0.0 0.0 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.0 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.0 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.0 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.0 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.0 GO:0060147 regulation of posttranscriptional gene silencing(GO:0060147) regulation of gene silencing by miRNA(GO:0060964) regulation of gene silencing by RNA(GO:0060966)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.0 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)