Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_RNA_DEGRADATION |
| Enrichment Score (ES) | -0.36722004 |
| Normalized Enrichment Score (NES) | -1.3331714 |
| Nominal p-value | 0.047904193 |
| FDR q-value | 0.33476666 |
| FWER p-Value | 0.991 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | EXOSC10 | NA | EXOSC10 Entrez, Source | exosome component 10 | 1086 | 2.185 | -0.0120 | No |
| 2 | ENO1 | NA | ENO1 Entrez, Source | enolase 1, (alpha) | 1506 | 1.760 | 0.0037 | No |
| 3 | LSM2 | NA | LSM2 Entrez, Source | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 1574 | 1.705 | 0.0378 | No |
| 4 | LSM1 | NA | LSM1 Entrez, Source | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 1900 | 1.474 | 0.0524 | No |
| 5 | SKIV2L | NA | SKIV2L Entrez, Source | superkiller viralicidic activity 2-like (S. cerevisiae) | 2316 | 1.248 | 0.0570 | No |
| 6 | DCP2 | NA | DCP2 Entrez, Source | DCP2 decapping enzyme homolog (S. cerevisiae) | 2878 | 1.037 | 0.0487 | No |
| 7 | CNOT7 | NA | CNOT7 Entrez, Source | CCR4-NOT transcription complex, subunit 7 | 2895 | 1.030 | 0.0707 | No |
| 8 | DCP1B | NA | DCP1B Entrez, Source | DCP1 decapping enzyme homolog B (S. cerevisiae) | 3519 | 0.850 | 0.0549 | No |
| 9 | CNOT6L | NA | CNOT6L Entrez, Source | CCR4-NOT transcription complex, subunit 6-like | 4219 | 0.715 | 0.0317 | No |
| 10 | HSPA9 | NA | 4653 | 0.628 | 0.0215 | No | ||
| 11 | CNOT4 | NA | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 4670 | 0.624 | 0.0345 | No |
| 12 | HSPD1 | NA | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 6826 | 0.318 | -0.0787 | No |
| 13 | CNOT8 | NA | CNOT8 Entrez, Source | CCR4-NOT transcription complex, subunit 8 | 7253 | 0.250 | -0.0969 | No |
| 14 | PAPOLB | NA | PAPOLB Entrez, Source | poly(A) polymerase beta (testis specific) | 7361 | 0.232 | -0.0977 | No |
| 15 | EXOSC4 | NA | EXOSC4 Entrez, Source | exosome component 4 | 7546 | 0.205 | -0.1034 | No |
| 16 | TTC37 | NA | 7686 | 0.187 | -0.1070 | No | ||
| 17 | ENO2 | NA | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 8063 | 0.137 | -0.1250 | No |
| 18 | EXOSC9 | NA | EXOSC9 Entrez, Source | exosome component 9 | 8904 | 0.028 | -0.1712 | No |
| 19 | EDC4 | NA | EDC4 Entrez, Source | enhancer of mRNA decapping 4 | 8907 | 0.028 | -0.1707 | No |
| 20 | EXOSC6 | NA | EXOSC6 Entrez, Source | exosome component 6 | 9135 | 0.006 | -0.1832 | No |
| 21 | PATL1 | NA | 9502 | -0.015 | -0.2033 | No | ||
| 22 | XRN1 | NA | XRN1 Entrez, Source | 5'-3' exoribonuclease 1 | 9552 | -0.022 | -0.2056 | No |
| 23 | PAPOLA | NA | PAPOLA Entrez, Source | poly(A) polymerase alpha | 9564 | -0.024 | -0.2057 | No |
| 24 | PAPD7 | NA | 10712 | -0.156 | -0.2662 | No | ||
| 25 | DDX6 | NA | DDX6 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 10859 | -0.178 | -0.2704 | No |
| 26 | XRN2 | NA | XRN2 Entrez, Source | 5'-3' exoribonuclease 2 | 10966 | -0.193 | -0.2720 | No |
| 27 | CNOT1 | NA | CNOT1 Entrez, Source | CCR4-NOT transcription complex, subunit 1 | 11142 | -0.218 | -0.2770 | No |
| 28 | EXOSC2 | NA | EXOSC2 Entrez, Source | exosome component 2 | 11987 | -0.338 | -0.3165 | No |
| 29 | ZCCHC7 | NA | ZCCHC7 Entrez, Source | zinc finger, CCHC domain containing 7 | 12105 | -0.355 | -0.3152 | No |
| 30 | DCP1A | NA | DCP1A Entrez, Source | DCP1 decapping enzyme homolog A (S. cerevisiae) | 12689 | -0.432 | -0.3381 | No |
| 31 | EXOSC1 | NA | EXOSC1 Entrez, Source | exosome component 1 | 12730 | -0.440 | -0.3306 | No |
| 32 | CNOT3 | NA | CNOT3 Entrez, Source | CCR4-NOT transcription complex, subunit 3 | 13066 | -0.465 | -0.3389 | No |
| 33 | EXOSC3 | NA | EXOSC3 Entrez, Source | exosome component 3 | 13178 | -0.484 | -0.3344 | No |
| 34 | MPHOSPH6 | NA | MPHOSPH6 Entrez, Source | M-phase phosphoprotein 6 | 13718 | -0.579 | -0.3516 | Yes |
| 35 | DCPS | NA | DCPS Entrez, Source | decapping enzyme, scavenger | 13798 | -0.594 | -0.3428 | Yes |
| 36 | CNOT2 | NA | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 14165 | -0.674 | -0.3482 | Yes |
| 37 | LSM4 | NA | LSM4 Entrez, Source | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 14506 | -0.755 | -0.3504 | Yes |
| 38 | LSM5 | NA | LSM5 Entrez, Source | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 14606 | -0.780 | -0.3386 | Yes |
| 39 | PARN | NA | PARN Entrez, Source | poly(A)-specific ribonuclease (deadenylation nuclease) | 15061 | -0.883 | -0.3444 | Yes |
| 40 | EXOSC5 | NA | EXOSC5 Entrez, Source | exosome component 5 | 15220 | -0.920 | -0.3327 | Yes |
| 41 | NAA38 | NA | 15229 | -0.923 | -0.3127 | Yes | ||
| 42 | EXOSC7 | NA | EXOSC7 Entrez, Source | exosome component 7 | 15361 | -0.959 | -0.2987 | Yes |
| 43 | LSM6 | NA | LSM6 Entrez, Source | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 15440 | -0.979 | -0.2813 | Yes |
| 44 | PNPT1 | NA | PNPT1 Entrez, Source | polyribonucleotide nucleotidyltransferase 1 | 15478 | -0.992 | -0.2613 | Yes |
| 45 | LSM7 | NA | LSM7 Entrez, Source | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 15726 | -1.069 | -0.2513 | Yes |
| 46 | LSM3 | NA | LSM3 Entrez, Source | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 15910 | -1.140 | -0.2362 | Yes |
| 47 | EDC3 | NA | EDC3 Entrez, Source | enhancer of mRNA decapping 3 homolog (S. cerevisiae) | 16084 | -1.207 | -0.2191 | Yes |
| 48 | PAPOLG | NA | PAPOLG Entrez, Source | poly(A) polymerase gamma | 16279 | -1.297 | -0.2011 | Yes |
| 49 | WDR61 | NA | WDR61 Entrez, Source | WD repeat domain 61 | 16843 | -1.640 | -0.1960 | Yes |
| 50 | DIS3 | NA | 16871 | -1.661 | -0.1606 | Yes | ||
| 51 | CNOT10 | NA | CNOT10 Entrez, Source | CCR4-NOT transcription complex, subunit 10 | 16909 | -1.688 | -0.1252 | Yes |
| 52 | EXOSC8 | NA | EXOSC8 Entrez, Source | exosome component 8 | 17073 | -1.837 | -0.0935 | Yes |
| 53 | C1D | NA | C1D Entrez, Source | - | 17189 | -1.994 | -0.0556 | Yes |
| 54 | SKIV2L2 | NA | SKIV2L2 Entrez, Source | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 17333 | -2.223 | -0.0142 | Yes |
| 55 | ENO3 | NA | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 17352 | -2.246 | 0.0347 | Yes |
