Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_MISMATCH_REPAIR |
| Enrichment Score (ES) | -0.45712718 |
| Normalized Enrichment Score (NES) | -1.3182974 |
| Nominal p-value | 0.122395836 |
| FDR q-value | 0.32084185 |
| FWER p-Value | 0.994 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RFC4 | NA | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 751 | 2.636 | 0.1079 | No |
| 2 | RPA4 | NA | RPA4 Entrez, Source | replication protein A4, 34kDa | 4013 | 0.759 | -0.0307 | No |
| 3 | MLH3 | NA | MLH3 Entrez, Source | mutL homolog 3 (E. coli) | 4647 | 0.629 | -0.0302 | No |
| 4 | RFC1 | NA | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 6374 | 0.385 | -0.1044 | No |
| 5 | RFC2 | NA | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 9589 | -0.028 | -0.2819 | No |
| 6 | MSH2 | NA | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 10163 | -0.085 | -0.3089 | No |
| 7 | RPA2 | NA | RPA2 Entrez, Source | replication protein A2, 32kDa | 10881 | -0.181 | -0.3386 | No |
| 8 | RPA1 | NA | RPA1 Entrez, Source | replication protein A1, 70kDa | 11194 | -0.226 | -0.3432 | No |
| 9 | PCNA | NA | PCNA Entrez, Source | proliferating cell nuclear antigen | 13241 | -0.495 | -0.4290 | Yes |
| 10 | MSH6 | NA | MSH6 Entrez, Source | mutS homolog 6 (E. coli) | 13437 | -0.525 | -0.4101 | Yes |
| 11 | PMS2 | NA | PMS2 Entrez, Source | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 13770 | -0.588 | -0.3951 | Yes |
| 12 | SSBP1 | NA | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 13780 | -0.591 | -0.3621 | Yes |
| 13 | POLD1 | NA | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 13802 | -0.595 | -0.3295 | Yes |
| 14 | POLD4 | NA | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 13855 | -0.605 | -0.2980 | Yes |
| 15 | RFC5 | NA | RFC5 Entrez, Source | replication factor C (activator 1) 5, 36.5kDa | 14006 | -0.636 | -0.2702 | Yes |
| 16 | RPA3 | NA | RPA3 Entrez, Source | replication protein A3, 14kDa | 14239 | -0.689 | -0.2440 | Yes |
| 17 | EXO1 | NA | EXO1 Entrez, Source | exonuclease 1 | 14354 | -0.715 | -0.2097 | Yes |
| 18 | POLD3 | NA | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 14617 | -0.783 | -0.1798 | Yes |
| 19 | POLD2 | NA | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 15203 | -0.914 | -0.1605 | Yes |
| 20 | MLH1 | NA | MLH1 Entrez, Source | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 15889 | -1.132 | -0.1343 | Yes |
| 21 | MSH3 | NA | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 16195 | -1.255 | -0.0801 | Yes |
| 22 | LIG1 | NA | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 16383 | -1.354 | -0.0136 | Yes |
| 23 | RFC3 | NA | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 17031 | -1.799 | 0.0525 | Yes |
