Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM |
| Enrichment Score (ES) | -0.6544524 |
| Normalized Enrichment Score (NES) | -1.7704991 |
| Nominal p-value | 0.00982801 |
| FDR q-value | 0.0449694 |
| FWER p-Value | 0.122 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MTHFD2L | NA | MTHFD2L Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 4274 | 0.707 | -0.1938 | No |
| 2 | MDH2 | NA | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 6688 | 0.336 | -0.3071 | No |
| 3 | CS | NA | CS Entrez, Source | citrate synthase | 6914 | 0.304 | -0.3006 | No |
| 4 | HAO2 | NA | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 8266 | 0.111 | -0.3689 | No |
| 5 | ACO2 | NA | ACO2 Entrez, Source | aconitase 2, mitochondrial | 8290 | 0.109 | -0.3634 | No |
| 6 | AFMID | NA | AFMID Entrez, Source | arylformamidase | 9437 | -0.005 | -0.4269 | No |
| 7 | GRHPR | NA | GRHPR Entrez, Source | glyoxylate reductase/hydroxypyruvate reductase | 12143 | -0.361 | -0.5550 | No |
| 8 | MTHFD1 | NA | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 12294 | -0.384 | -0.5394 | No |
| 9 | HYI | NA | HYI Entrez, Source | hydroxypyruvate isomerase homolog (E. coli) | 12880 | -0.448 | -0.5439 | No |
| 10 | PGP | NA | PGP Entrez, Source | phosphoglycolate phosphatase | 14129 | -0.664 | -0.5719 | No |
| 11 | ACO1 | NA | ACO1 Entrez, Source | aconitase 1, soluble | 15335 | -0.951 | -0.5795 | Yes |
| 12 | MTHFD1L | NA | MTHFD1L Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 16682 | -1.520 | -0.5594 | Yes |
| 13 | GLYCTK | NA | GLYCTK Entrez, Source | - | 16847 | -1.643 | -0.4658 | Yes |
| 14 | MDH1 | NA | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 17141 | -1.921 | -0.3621 | Yes |
| 15 | MTHFD2 | NA | MTHFD2 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 17262 | -2.101 | -0.2374 | Yes |
| 16 | HAO1 | NA | HAO1 Entrez, Source | hydroxyacid oxidase (glycolate oxidase) 1 | 17917 | -4.430 | 0.0032 | Yes |
