Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES |
| Enrichment Score (ES) | -0.64182675 |
| Normalized Enrichment Score (NES) | -1.7115228 |
| Nominal p-value | 0.014851485 |
| FDR q-value | 0.034295846 |
| FWER p-Value | 0.21 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ST3GAL5 | NA | ST3GAL5 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3100 | 0.963 | -0.1213 | No |
| 2 | ST8SIA1 | NA | ST8SIA1 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 3193 | 0.941 | -0.0763 | No |
| 3 | B3GALT4 | NA | B3GALT4 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 | 4343 | 0.691 | -0.1035 | No |
| 4 | ST3GAL2 | NA | ST3GAL2 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | 4873 | 0.581 | -0.1020 | No |
| 5 | HEXB | NA | HEXB Entrez, Source | hexosaminidase B (beta polypeptide) | 6574 | 0.354 | -0.1778 | No |
| 6 | ST6GALNAC6 | NA | ST6GALNAC6 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 | 7924 | 0.154 | -0.2447 | No |
| 7 | SLC33A1 | NA | SLC33A1 Entrez, Source | solute carrier family 33 (acetyl-CoA transporter), member 1 | 10367 | -0.105 | -0.3751 | No |
| 8 | GLB1 | NA | GLB1 Entrez, Source | galactosidase, beta 1 | 10615 | -0.143 | -0.3812 | No |
| 9 | ST6GALNAC4 | NA | ST6GALNAC4 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | 11791 | -0.309 | -0.4302 | No |
| 10 | ST8SIA5 | NA | ST8SIA5 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | 14070 | -0.651 | -0.5223 | No |
| 11 | ST3GAL1 | NA | ST3GAL1 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 16217 | -1.267 | -0.5743 | Yes |
| 12 | B4GALNT1 | NA | B4GALNT1 Entrez, Source | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 17135 | -1.909 | -0.5237 | Yes |
| 13 | HEXA | NA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 17427 | -2.374 | -0.4135 | Yes |
| 14 | ST6GALNAC3 | NA | ST6GALNAC3 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 17885 | -4.160 | -0.2173 | Yes |
| 15 | ST6GALNAC5 | NA | ST6GALNAC5 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 17888 | -4.171 | 0.0048 | Yes |
