Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | KEGG_CELL_ADHESION_MOLECULES_CAMS |
| Enrichment Score (ES) | 0.4206797 |
| Normalized Enrichment Score (NES) | 1.5556808 |
| Nominal p-value | 0.0013280213 |
| FDR q-value | 0.07487209 |
| FWER p-Value | 0.783 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HLA-DRB1 | NA | HLA-DRB1 Entrez, Source | major histocompatibility complex, class II, DR beta 1 | 8 | 4.960 | 0.0290 | Yes |
| 2 | HLA-DRA | NA | HLA-DRA Entrez, Source | major histocompatibility complex, class II, DR alpha | 27 | 4.871 | 0.0569 | Yes |
| 3 | ICOSLG | NA | ICOSLG Entrez, Source | inducible T-cell co-stimulator ligand | 88 | 4.556 | 0.0806 | Yes |
| 4 | HLA-DPA1 | NA | HLA-DPA1 Entrez, Source | major histocompatibility complex, class II, DP alpha 1 | 107 | 4.489 | 0.1062 | Yes |
| 5 | CLDN1 | NA | CLDN1 Entrez, Source | claudin 1 | 125 | 4.398 | 0.1313 | Yes |
| 6 | HLA-DRB5 | NA | HLA-DRB5 Entrez, Source | major histocompatibility complex, class II, DR beta 5 | 137 | 4.339 | 0.1565 | Yes |
| 7 | SELL | NA | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 146 | 4.309 | 0.1816 | Yes |
| 8 | HLA-DMB | NA | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 164 | 4.259 | 0.2059 | Yes |
| 9 | CLDN4 | NA | CLDN4 Entrez, Source | claudin 4 | 194 | 4.143 | 0.2289 | Yes |
| 10 | HLA-DRB3 | NA | HLA-DRB3 Entrez, Source | major histocompatibility complex, class II, DR beta 3 | 226 | 4.018 | 0.2510 | Yes |
| 11 | HLA-DRB4 | NA | HLA-DRB4 Entrez, Source | major histocompatibility complex, class II, DR beta 4 | 242 | 3.963 | 0.2736 | Yes |
| 12 | NLGN1 | NA | NLGN1 Entrez, Source | neuroligin 1 | 258 | 3.876 | 0.2958 | Yes |
| 13 | HLA-DMA | NA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 294 | 3.747 | 0.3161 | Yes |
| 14 | CLDN23 | NA | CLDN23 Entrez, Source | claudin 23 | 361 | 3.553 | 0.3335 | Yes |
| 15 | HLA-DQB1 | NA | HLA-DQB1 Entrez, Source | major histocompatibility complex, class II, DQ beta 1 | 438 | 3.353 | 0.3491 | Yes |
| 16 | CLDN3 | NA | CLDN3 Entrez, Source | claudin 3 | 647 | 2.857 | 0.3544 | Yes |
| 17 | OCLN | NA | OCLN Entrez, Source | occludin | 760 | 2.621 | 0.3637 | Yes |
| 18 | CNTN1 | NA | CNTN1 Entrez, Source | contactin 1 | 811 | 2.535 | 0.3759 | Yes |
| 19 | CD22 | NA | CD22 Entrez, Source | CD22 molecule | 1074 | 2.196 | 0.3743 | Yes |
| 20 | CDH2 | NA | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 1082 | 2.192 | 0.3869 | Yes |
| 21 | HLA-DPB1 | NA | HLA-DPB1 Entrez, Source | major histocompatibility complex, class II, DP beta 1 | 1127 | 2.142 | 0.3971 | Yes |
| 22 | CLDN2 | NA | CLDN2 Entrez, Source | claudin 2 | 1173 | 2.068 | 0.4069 | Yes |
| 23 | HLA-DOB | NA | HLA-DOB Entrez, Source | major histocompatibility complex, class II, DO beta | 1460 | 1.797 | 0.4015 | Yes |
| 24 | HLA-E | NA | HLA-E Entrez, Source | major histocompatibility complex, class I, E | 1528 | 1.738 | 0.4081 | Yes |
| 25 | NRCAM | NA | NRCAM Entrez, Source | neuronal cell adhesion molecule | 1585 | 1.699 | 0.4150 | Yes |
| 26 | HLA-DOA | NA | HLA-DOA Entrez, Source | major histocompatibility complex, class II, DO alpha | 1660 | 1.640 | 0.4206 | Yes |
| 27 | ICAM1 | NA | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 1997 | 1.422 | 0.4102 | Yes |
| 28 | CD99 | NA | CD99 Entrez, Source | CD99 molecule | 2001 | 1.420 | 0.4185 | Yes |
| 29 | PECAM1 | NA | PECAM1 Entrez, Source | platelet/endothelial cell adhesion molecule (CD31 antigen) | 2148 | 1.334 | 0.4182 | Yes |
| 30 | CD34 | NA | CD34 Entrez, Source | CD34 molecule | 2241 | 1.284 | 0.4207 | Yes |
| 31 | CLDN9 | NA | CLDN9 Entrez, Source | claudin 9 | 2505 | 1.177 | 0.4129 | No |
| 32 | PVR | NA | PVR Entrez, Source | poliovirus receptor | 2749 | 1.079 | 0.4057 | No |
| 33 | SDC2 | NA | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 2815 | 1.055 | 0.4083 | No |
| 34 | CTLA4 | NA | CTLA4 Entrez, Source | cytotoxic T-lymphocyte-associated protein 4 | 3119 | 0.957 | 0.3970 | No |
| 35 | CD58 | NA | CD58 Entrez, Source | CD58 molecule | 3252 | 0.926 | 0.3951 | No |
| 36 | NRXN1 | NA | NRXN1 Entrez, Source | neurexin 1 | 3386 | 0.885 | 0.3929 | No |
| 37 | CLDN14 | NA | CLDN14 Entrez, Source | claudin 14 | 3483 | 0.861 | 0.3927 | No |
| 38 | ALCAM | NA | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 3764 | 0.818 | 0.3818 | No |
| 39 | ITGAV | NA | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 3832 | 0.802 | 0.3828 | No |
| 40 | F11R | NA | F11R Entrez, Source | F11 receptor | 4052 | 0.751 | 0.3750 | No |
| 41 | CLDN16 | NA | CLDN16 Entrez, Source | claudin 16 | 4183 | 0.723 | 0.3720 | No |
| 42 | MPZL1 | NA | MPZL1 Entrez, Source | myelin protein zero-like 1 | 4258 | 0.711 | 0.3721 | No |
| 43 | HLA-C | NA | HLA-C Entrez, Source | major histocompatibility complex, class I, C | 4338 | 0.693 | 0.3718 | No |
| 44 | PTPRM | NA | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 4432 | 0.672 | 0.3705 | No |
| 45 | ITGA6 | NA | ITGA6 Entrez, Source | integrin, alpha 6 | 4506 | 0.656 | 0.3704 | No |
| 46 | HLA-G | NA | HLA-G Entrez, Source | HLA-G histocompatibility antigen, class I, G | 4577 | 0.642 | 0.3702 | No |
| 47 | CDH1 | NA | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 4645 | 0.630 | 0.3702 | No |
| 48 | HLA-A | NA | HLA-A Entrez, Source | major histocompatibility complex, class I, A | 4720 | 0.613 | 0.3697 | No |
| 49 | HLA-F | NA | HLA-F Entrez, Source | major histocompatibility complex, class I, F | 4736 | 0.609 | 0.3725 | No |
| 50 | CNTNAP2 | NA | CNTNAP2 Entrez, Source | contactin associated protein-like 2 | 4807 | 0.593 | 0.3721 | No |
| 51 | CLDN18 | NA | CLDN18 Entrez, Source | claudin 18 | 5037 | 0.548 | 0.3625 | No |
| 52 | NLGN3 | NA | NLGN3 Entrez, Source | neuroligin 3 | 5349 | 0.492 | 0.3480 | No |
| 53 | VCAM1 | NA | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 5750 | 0.437 | 0.3282 | No |
| 54 | CLDN22 | NA | CLDN22 Entrez, Source | claudin 22 | 5848 | 0.428 | 0.3253 | No |
| 55 | CLDN20 | NA | CLDN20 Entrez, Source | claudin 20 | 5928 | 0.424 | 0.3234 | No |
| 56 | CD2 | NA | CD2 Entrez, Source | CD2 molecule | 6092 | 0.415 | 0.3167 | No |
| 57 | HLA-DQA1 | NA | HLA-DQA1 Entrez, Source | major histocompatibility complex, class II, DQ alpha 1 | 6116 | 0.415 | 0.3179 | No |
| 58 | CADM3 | NA | 6143 | 0.415 | 0.3189 | No | ||
| 59 | GLG1 | NA | GLG1 Entrez, Source | golgi apparatus protein 1 | 6230 | 0.410 | 0.3165 | No |
| 60 | NRXN2 | NA | NRXN2 Entrez, Source | neurexin 2 | 6737 | 0.329 | 0.2901 | No |
| 61 | JAM2 | NA | JAM2 Entrez, Source | junctional adhesion molecule 2 | 7164 | 0.264 | 0.2678 | No |
| 62 | SELE | NA | SELE Entrez, Source | selectin E (endothelial adhesion molecule 1) | 7215 | 0.255 | 0.2665 | No |
| 63 | CD274 | NA | CD274 Entrez, Source | CD274 molecule | 7216 | 0.255 | 0.2680 | No |
| 64 | CD8A | NA | CD8A Entrez, Source | CD8a molecule | 7312 | 0.240 | 0.2641 | No |
| 65 | CNTN2 | NA | CNTN2 Entrez, Source | contactin 2 (axonal) | 7473 | 0.214 | 0.2564 | No |
| 66 | ITGA4 | NA | ITGA4 Entrez, Source | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 7633 | 0.196 | 0.2487 | No |
| 67 | CLDN6 | NA | CLDN6 Entrez, Source | claudin 6 | 7657 | 0.191 | 0.2485 | No |
| 68 | CLDN10 | NA | CLDN10 Entrez, Source | claudin 10 | 7783 | 0.174 | 0.2425 | No |
| 69 | CLDN8 | NA | CLDN8 Entrez, Source | claudin 8 | 7951 | 0.151 | 0.2341 | No |
| 70 | SELP | NA | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 8440 | 0.088 | 0.2072 | No |
| 71 | SDC3 | NA | SDC3 Entrez, Source | syndecan 3 (N-syndecan) | 8638 | 0.061 | 0.1966 | No |
| 72 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 8759 | 0.043 | 0.1901 | No |
| 73 | NCAM1 | NA | NCAM1 Entrez, Source | neural cell adhesion molecule 1 | 8960 | 0.019 | 0.1790 | No |
| 74 | ICOS | NA | ICOS Entrez, Source | inducible T-cell co-stimulator | 9264 | 0.000 | 0.1620 | No |
| 75 | ITGB1 | NA | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 9602 | -0.030 | 0.1433 | No |
| 76 | ITGAL | NA | ITGAL Entrez, Source | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 9755 | -0.047 | 0.1351 | No |
| 77 | ITGB7 | NA | ITGB7 Entrez, Source | integrin, beta 7 | 9842 | -0.057 | 0.1306 | No |
| 78 | CD4 | NA | CD4 Entrez, Source | CD4 molecule | 9976 | -0.068 | 0.1235 | No |
| 79 | NFASC | NA | NFASC Entrez, Source | neurofascin homolog (chicken) | 10311 | -0.097 | 0.1054 | No |
| 80 | ITGA8 | NA | ITGA8 Entrez, Source | integrin, alpha 8 | 10364 | -0.104 | 0.1031 | No |
| 81 | CD80 | NA | CD80 Entrez, Source | CD80 molecule | 10403 | -0.111 | 0.1016 | No |
| 82 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 10626 | -0.143 | 0.0900 | No |
| 83 | SPN | NA | SPN Entrez, Source | sialophorin (leukosialin, CD43) | 10773 | -0.164 | 0.0828 | No |
| 84 | ESAM | NA | ESAM Entrez, Source | endothelial cell adhesion molecule | 10822 | -0.172 | 0.0812 | No |
| 85 | CD86 | NA | CD86 Entrez, Source | CD86 molecule | 10856 | -0.177 | 0.0804 | No |
| 86 | CLDN5 | NA | CLDN5 Entrez, Source | claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) | 11081 | -0.209 | 0.0691 | No |
| 87 | MADCAM1 | NA | MADCAM1 Entrez, Source | mucosal vascular addressin cell adhesion molecule 1 | 11084 | -0.209 | 0.0702 | No |
| 88 | HLA-DQA2 | NA | HLA-DQA2 Entrez, Source | major histocompatibility complex, class II, DQ alpha 2 | 11354 | -0.247 | 0.0566 | No |
| 89 | ITGB8 | NA | ITGB8 Entrez, Source | integrin, beta 8 | 11443 | -0.261 | 0.0532 | No |
| 90 | CLDN19 | NA | CLDN19 Entrez, Source | claudin 19 | 11526 | -0.275 | 0.0502 | No |
| 91 | ICAM2 | NA | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 11697 | -0.295 | 0.0425 | No |
| 92 | SDC4 | NA | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 11969 | -0.335 | 0.0293 | No |
| 93 | NEGR1 | NA | NEGR1 Entrez, Source | neuronal growth regulator 1 | 12059 | -0.347 | 0.0263 | No |
| 94 | ICAM3 | NA | ICAM3 Entrez, Source | intercellular adhesion molecule 3 | 12195 | -0.368 | 0.0210 | No |
| 95 | PDCD1 | NA | PDCD1 Entrez, Source | programmed cell death 1 | 12256 | -0.376 | 0.0198 | No |
| 96 | CDH15 | NA | CDH15 Entrez, Source | cadherin 15, M-cadherin (myotubule) | 12444 | -0.408 | 0.0118 | No |
| 97 | CD40LG | NA | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 12489 | -0.411 | 0.0117 | No |
| 98 | CLDN11 | NA | CLDN11 Entrez, Source | claudin 11 (oligodendrocyte transmembrane protein) | 12876 | -0.448 | -0.0072 | No |
| 99 | CLDN17 | NA | CLDN17 Entrez, Source | claudin 17 | 12921 | -0.451 | -0.0070 | No |
| 100 | CDH3 | NA | CDH3 Entrez, Source | cadherin 3, type 1, P-cadherin (placental) | 13000 | -0.456 | -0.0087 | No |
| 101 | SELPLG | NA | SELPLG Entrez, Source | selectin P ligand | 13314 | -0.505 | -0.0232 | No |
| 102 | SIGLEC1 | NA | SIGLEC1 Entrez, Source | sialic acid binding Ig-like lectin 1, sialoadhesin | 13430 | -0.523 | -0.0266 | No |
| 103 | CLDN15 | NA | CLDN15 Entrez, Source | claudin 15 | 13587 | -0.555 | -0.0320 | No |
| 104 | NLGN2 | NA | NLGN2 Entrez, Source | neuroligin 2 | 13589 | -0.555 | -0.0288 | No |
| 105 | CDH5 | NA | CDH5 Entrez, Source | cadherin 5, type 2, VE-cadherin (vascular epithelium) | 14303 | -0.701 | -0.0646 | No |
| 106 | MAG | NA | MAG Entrez, Source | myelin associated glycoprotein | 14339 | -0.711 | -0.0623 | No |
| 107 | PDCD1LG2 | NA | PDCD1LG2 Entrez, Source | programmed cell death 1 ligand 2 | 14363 | -0.717 | -0.0593 | No |
| 108 | CD226 | NA | CD226 Entrez, Source | CD226 molecule | 14840 | -0.837 | -0.0811 | No |
| 109 | SDC1 | NA | SDC1 Entrez, Source | syndecan 1 | 14863 | -0.838 | -0.0773 | No |
| 110 | ITGB2 | NA | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 14916 | -0.848 | -0.0752 | No |
| 111 | CD276 | NA | CD276 Entrez, Source | CD276 molecule | 14979 | -0.862 | -0.0736 | No |
| 112 | NCAM2 | NA | NCAM2 Entrez, Source | neural cell adhesion molecule 2 | 15167 | -0.907 | -0.0787 | No |
| 113 | NLGN4X | NA | NLGN4X Entrez, Source | neuroligin 4, X-linked | 15424 | -0.975 | -0.0872 | No |
| 114 | CLDN7 | NA | CLDN7 Entrez, Source | claudin 7 | 15646 | -1.041 | -0.0934 | No |
| 115 | PTPRF | NA | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 15746 | -1.077 | -0.0926 | No |
| 116 | CNTNAP1 | NA | CNTNAP1 Entrez, Source | contactin associated protein 1 | 16744 | -1.560 | -0.1392 | No |
| 117 | MPZ | NA | MPZ Entrez, Source | myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) | 16807 | -1.611 | -0.1331 | No |
| 118 | CD28 | NA | CD28 Entrez, Source | CD28 molecule | 17036 | -1.802 | -0.1352 | No |
| 119 | ITGAM | NA | ITGAM Entrez, Source | integrin, alpha M (complement component 3 receptor 3 subunit) | 17198 | -2.003 | -0.1323 | No |
| 120 | L1CAM | NA | L1CAM Entrez, Source | L1 cell adhesion molecule | 17216 | -2.028 | -0.1212 | No |
| 121 | CDH4 | NA | CDH4 Entrez, Source | cadherin 4, type 1, R-cadherin (retinal) | 17227 | -2.049 | -0.1096 | No |
| 122 | ITGA9 | NA | ITGA9 Entrez, Source | integrin, alpha 9 | 17315 | -2.199 | -0.1015 | No |
| 123 | CD40 | NA | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 17453 | -2.414 | -0.0948 | No |
| 124 | JAM3 | NA | JAM3 Entrez, Source | junctional adhesion molecule 3 | 17589 | -2.733 | -0.0862 | No |
| 125 | CADM1 | NA | 17717 | -3.164 | -0.0745 | No | ||
| 126 | NEO1 | NA | NEO1 Entrez, Source | neogenin homolog 1 (chicken) | 17732 | -3.248 | -0.0560 | No |
| 127 | CD6 | NA | CD6 Entrez, Source | CD6 molecule | 17764 | -3.424 | -0.0374 | No |
| 128 | NRXN3 | NA | NRXN3 Entrez, Source | neurexin 3 | 17808 | -3.618 | -0.0184 | No |
| 129 | VCAN | NA | 17935 | -4.655 | 0.0022 | No |
