Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | HALLMARK_XENOBIOTIC_METABOLISM |
| Enrichment Score (ES) | 0.492954 |
| Normalized Enrichment Score (NES) | 1.9062393 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.4313725E-4 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ALDH3A1 | NA | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 31 | 4.860 | 0.0181 | Yes |
| 2 | GCKR | NA | GCKR Entrez, Source | glucokinase (hexokinase 4) regulator | 56 | 4.689 | 0.0358 | Yes |
| 3 | ATOH8 | NA | ATOH8 Entrez, Source | atonal homolog 8 (Drosophila) | 73 | 4.603 | 0.0537 | Yes |
| 4 | CYP1A1 | NA | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 75 | 4.587 | 0.0723 | Yes |
| 5 | AKR1C3 | NA | AKR1C3 Entrez, Source | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 83 | 4.572 | 0.0905 | Yes |
| 6 | PDK4 | NA | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 122 | 4.421 | 0.1064 | Yes |
| 7 | IL1R1 | NA | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 124 | 4.410 | 0.1243 | Yes |
| 8 | ABCC3 | NA | ABCC3 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 185 | 4.181 | 0.1380 | Yes |
| 9 | CYP2J2 | NA | CYP2J2 Entrez, Source | cytochrome P450, family 2, subfamily J, polypeptide 2 | 210 | 4.092 | 0.1533 | Yes |
| 10 | ID2 | NA | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 272 | 3.826 | 0.1655 | Yes |
| 11 | AKR1C2 | NA | AKR1C2 Entrez, Source | aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) | 295 | 3.746 | 0.1795 | Yes |
| 12 | IGFBP4 | NA | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 372 | 3.508 | 0.1895 | Yes |
| 13 | JUP | NA | JUP Entrez, Source | junction plakoglobin | 377 | 3.496 | 0.2036 | Yes |
| 14 | FMO3 | NA | FMO3 Entrez, Source | flavin containing monooxygenase 3 | 393 | 3.445 | 0.2168 | Yes |
| 15 | CES1 | NA | CES1 Entrez, Source | carboxylesterase 1 (monocyte/macrophage serine esterase 1) | 411 | 3.407 | 0.2297 | Yes |
| 16 | DDAH2 | NA | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 414 | 3.402 | 0.2434 | Yes |
| 17 | EPHX1 | NA | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 429 | 3.367 | 0.2564 | Yes |
| 18 | PTGR1 | NA | 519 | 3.136 | 0.2641 | Yes | ||
| 19 | GSR | NA | GSR Entrez, Source | glutathione reductase | 576 | 2.988 | 0.2732 | Yes |
| 20 | HMOX1 | NA | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 614 | 2.923 | 0.2830 | Yes |
| 21 | SERPINE1 | NA | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 620 | 2.910 | 0.2946 | Yes |
| 22 | ADH1C | NA | ADH1C Entrez, Source | alcohol dehydrogenase 1C (class I), gamma polypeptide | 628 | 2.899 | 0.3060 | Yes |
| 23 | EPHA2 | NA | EPHA2 Entrez, Source | EPH receptor A2 | 650 | 2.849 | 0.3164 | Yes |
| 24 | SPINT2 | NA | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 671 | 2.787 | 0.3267 | Yes |
| 25 | KYNU | NA | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 675 | 2.781 | 0.3378 | Yes |
| 26 | PINK1 | NA | PINK1 Entrez, Source | PTEN induced putative kinase 1 | 707 | 2.718 | 0.3472 | Yes |
| 27 | CA2 | NA | CA2 Entrez, Source | carbonic anhydrase II | 737 | 2.653 | 0.3563 | Yes |
| 28 | MT2A | NA | MT2A Entrez, Source | metallothionein 2A | 836 | 2.492 | 0.3610 | Yes |
| 29 | PGD | NA | PGD Entrez, Source | phosphogluconate dehydrogenase | 863 | 2.460 | 0.3695 | Yes |
| 30 | NPC1 | NA | NPC1 Entrez, Source | Niemann-Pick disease, type C1 | 924 | 2.390 | 0.3759 | Yes |
| 31 | IGFBP1 | NA | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 929 | 2.388 | 0.3854 | Yes |
| 32 | GABARAPL1 | NA | GABARAPL1 Entrez, Source | GABA(A) receptor-associated protein like 1 | 957 | 2.334 | 0.3934 | Yes |
| 33 | GCLC | NA | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 988 | 2.302 | 0.4011 | Yes |
| 34 | CFB | NA | CFB Entrez, Source | complement factor B | 1197 | 2.041 | 0.3977 | Yes |
| 35 | LPIN2 | NA | LPIN2 Entrez, Source | lipin 2 | 1294 | 1.938 | 0.4002 | Yes |
| 36 | NQO1 | NA | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 1308 | 1.922 | 0.4073 | Yes |
| 37 | UGDH | NA | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1332 | 1.899 | 0.4138 | Yes |
| 38 | CYP2S1 | NA | CYP2S1 Entrez, Source | cytochrome P450, family 2, subfamily S, polypeptide 1 | 1366 | 1.872 | 0.4195 | Yes |
| 39 | APOE | NA | APOE Entrez, Source | apolipoprotein E | 1420 | 1.827 | 0.4240 | Yes |
| 40 | TTPA | NA | TTPA Entrez, Source | tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) | 1459 | 1.798 | 0.4292 | Yes |
| 41 | PDLIM5 | NA | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 1472 | 1.784 | 0.4358 | Yes |
| 42 | GCNT2 | NA | GCNT2 Entrez, Source | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 1605 | 1.683 | 0.4352 | Yes |
| 43 | CYP2E1 | NA | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 1641 | 1.652 | 0.4400 | Yes |
| 44 | PTGES | NA | PTGES Entrez, Source | prostaglandin E synthase | 1674 | 1.631 | 0.4448 | Yes |
| 45 | CDA | NA | CDA Entrez, Source | cytidine deaminase | 1705 | 1.598 | 0.4497 | Yes |
| 46 | FAS | NA | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 1716 | 1.589 | 0.4556 | Yes |
| 47 | MAN1A1 | NA | MAN1A1 Entrez, Source | mannosidase, alpha, class 1A, member 1 | 1846 | 1.500 | 0.4544 | Yes |
| 48 | PLG | NA | PLG Entrez, Source | plasminogen | 1857 | 1.494 | 0.4600 | Yes |
| 49 | TNFRSF1A | NA | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 1923 | 1.460 | 0.4623 | Yes |
| 50 | NINJ1 | NA | NINJ1 Entrez, Source | ninjurin 1 | 1947 | 1.445 | 0.4668 | Yes |
| 51 | CASP6 | NA | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 1996 | 1.422 | 0.4699 | Yes |
| 52 | IDH1 | NA | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1999 | 1.421 | 0.4756 | Yes |
| 53 | GAD1 | NA | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 2048 | 1.394 | 0.4786 | Yes |
| 54 | DHRS1 | NA | DHRS1 Entrez, Source | dehydrogenase/reductase (SDR family) member 1 | 2102 | 1.361 | 0.4812 | Yes |
| 55 | ABHD6 | NA | ABHD6 Entrez, Source | abhydrolase domain containing 6 | 2111 | 1.354 | 0.4862 | Yes |
| 56 | SLC6A6 | NA | SLC6A6 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 2161 | 1.327 | 0.4889 | Yes |
| 57 | ETFDH | NA | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 2185 | 1.316 | 0.4930 | Yes |
| 58 | SAR1B | NA | SAR1B Entrez, Source | SAR1 gene homolog B (S. cerevisiae) | 2312 | 1.249 | 0.4910 | No |
| 59 | SERTAD1 | NA | SERTAD1 Entrez, Source | SERTA domain containing 1 | 2485 | 1.185 | 0.4861 | No |
| 60 | ADH5 | NA | ADH5 Entrez, Source | alcohol dehydrogenase 5 (class III), chi polypeptide | 2762 | 1.074 | 0.4750 | No |
| 61 | HGFAC | NA | HGFAC Entrez, Source | HGF activator | 2828 | 1.051 | 0.4756 | No |
| 62 | ANGPTL3 | NA | ANGPTL3 Entrez, Source | angiopoietin-like 3 | 2936 | 1.011 | 0.4737 | No |
| 63 | PPARD | NA | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 3037 | 0.978 | 0.4721 | No |
| 64 | CYP1A2 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 3060 | 0.973 | 0.4748 | No |
| 65 | ABCD2 | NA | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 3125 | 0.954 | 0.4751 | No |
| 66 | DHRS7 | NA | DHRS7 Entrez, Source | dehydrogenase/reductase (SDR family) member 7 | 3239 | 0.930 | 0.4725 | No |
| 67 | CROT | NA | CROT Entrez, Source | carnitine O-octanoyltransferase | 3254 | 0.925 | 0.4755 | No |
| 68 | BLVRB | NA | BLVRB Entrez, Source | biliverdin reductase B (flavin reductase (NADPH)) | 3299 | 0.912 | 0.4767 | No |
| 69 | TGFB2 | NA | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 3389 | 0.883 | 0.4753 | No |
| 70 | NFS1 | NA | NFS1 Entrez, Source | NFS1 nitrogen fixation 1 (S. cerevisiae) | 3440 | 0.873 | 0.4761 | No |
| 71 | ACOX1 | NA | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 3448 | 0.871 | 0.4792 | No |
| 72 | POR | NA | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 3500 | 0.856 | 0.4798 | No |
| 73 | SLC35D1 | NA | SLC35D1 Entrez, Source | solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 | 3502 | 0.856 | 0.4833 | No |
| 74 | BCAR1 | NA | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 3589 | 0.843 | 0.4819 | No |
| 75 | CBR1 | NA | CBR1 Entrez, Source | carbonyl reductase 1 | 3602 | 0.841 | 0.4846 | No |
| 76 | ALDH2 | NA | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 3635 | 0.839 | 0.4862 | No |
| 77 | ACP2 | NA | ACP2 Entrez, Source | acid phosphatase 2, lysosomal | 4051 | 0.751 | 0.4660 | No |
| 78 | DHPS | NA | DHPS Entrez, Source | deoxyhypusine synthase | 4375 | 0.684 | 0.4506 | No |
| 79 | DDC | NA | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 4637 | 0.632 | 0.4385 | No |
| 80 | CSAD | NA | CSAD Entrez, Source | cysteine sulfinic acid decarboxylase | 4700 | 0.616 | 0.4375 | No |
| 81 | ATP2A2 | NA | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 4905 | 0.576 | 0.4284 | No |
| 82 | FBP1 | NA | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 4937 | 0.571 | 0.4290 | No |
| 83 | F11 | NA | F11 Entrez, Source | coagulation factor XI (plasma thromboplastin antecedent) | 5236 | 0.512 | 0.4143 | No |
| 84 | CYP4F2 | NA | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 5314 | 0.499 | 0.4120 | No |
| 85 | PMM1 | NA | PMM1 Entrez, Source | phosphomannomutase 1 | 5385 | 0.489 | 0.4100 | No |
| 86 | PC | NA | PC Entrez, Source | pyruvate carboxylase | 5473 | 0.482 | 0.4071 | No |
| 87 | ACOX3 | NA | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 5632 | 0.455 | 0.4001 | No |
| 88 | VTN | NA | VTN Entrez, Source | vitronectin | 5658 | 0.451 | 0.4005 | No |
| 89 | SMOX | NA | SMOX Entrez, Source | spermine oxidase | 5673 | 0.448 | 0.4016 | No |
| 90 | FETUB | NA | FETUB Entrez, Source | fetuin B | 5737 | 0.438 | 0.3998 | No |
| 91 | HNF4A | NA | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 6236 | 0.409 | 0.3735 | No |
| 92 | ITIH4 | NA | ITIH4 Entrez, Source | inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) | 6333 | 0.392 | 0.3697 | No |
| 93 | ACSM1 | NA | ACSM1 Entrez, Source | acyl-CoA synthetase medium-chain family member 1 | 6736 | 0.329 | 0.3484 | No |
| 94 | AQP9 | NA | AQP9 Entrez, Source | aquaporin 9 | 6765 | 0.326 | 0.3481 | No |
| 95 | ABCC2 | NA | ABCC2 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 6897 | 0.307 | 0.3420 | No |
| 96 | FAH | NA | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 7022 | 0.286 | 0.3362 | No |
| 97 | NDRG2 | NA | NDRG2 Entrez, Source | NDRG family member 2 | 7308 | 0.241 | 0.3212 | No |
| 98 | PSMB10 | NA | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 7443 | 0.219 | 0.3145 | No |
| 99 | FMO1 | NA | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 7504 | 0.210 | 0.3120 | No |
| 100 | SLC1A5 | NA | SLC1A5 Entrez, Source | solute carrier family 1 (neutral amino acid transporter), member 5 | 7505 | 0.210 | 0.3129 | No |
| 101 | ELOVL5 | NA | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 7578 | 0.201 | 0.3096 | No |
| 102 | CYP27A1 | NA | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 7891 | 0.159 | 0.2927 | No |
| 103 | CYP26A1 | NA | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 7989 | 0.147 | 0.2879 | No |
| 104 | ACO2 | NA | ACO2 Entrez, Source | aconitase 2, mitochondrial | 8290 | 0.109 | 0.2714 | No |
| 105 | SLC12A4 | NA | SLC12A4 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 4 | 8314 | 0.105 | 0.2706 | No |
| 106 | ENPEP | NA | ENPEP Entrez, Source | glutamyl aminopeptidase (aminopeptidase A) | 8480 | 0.081 | 0.2616 | No |
| 107 | MAOA | NA | MAOA Entrez, Source | monoamine oxidase A | 8517 | 0.077 | 0.2599 | No |
| 108 | ALAS1 | NA | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 8862 | 0.035 | 0.2407 | No |
| 109 | TDO2 | NA | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 8889 | 0.030 | 0.2394 | No |
| 110 | DDT | NA | DDT Entrez, Source | D-dopachrome tautomerase | 8918 | 0.026 | 0.2379 | No |
| 111 | TPST1 | NA | TPST1 Entrez, Source | tyrosylprotein sulfotransferase 1 | 8931 | 0.023 | 0.2373 | No |
| 112 | REG1A | NA | REG1A Entrez, Source | regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein) | 9113 | 0.009 | 0.2272 | No |
| 113 | HSD17B2 | NA | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 9170 | 0.002 | 0.2240 | No |
| 114 | GSTT2 | NA | GSTT2 Entrez, Source | glutathione S-transferase theta 2 | 9186 | 0.000 | 0.2232 | No |
| 115 | PTGDS | NA | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 9231 | 0.000 | 0.2207 | No |
| 116 | CD36 | NA | CD36 Entrez, Source | CD36 molecule (thrombospondin receptor) | 9407 | -0.000 | 0.2109 | No |
| 117 | F10 | NA | F10 Entrez, Source | coagulation factor X | 9456 | -0.007 | 0.2082 | No |
| 118 | RAP1GAP | NA | RAP1GAP Entrez, Source | RAP1 GTPase activating protein | 9465 | -0.008 | 0.2078 | No |
| 119 | PTGES3 | NA | PTGES3 Entrez, Source | prostaglandin E synthase 3 (cytosolic) | 9493 | -0.014 | 0.2063 | No |
| 120 | G6PC | NA | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 9498 | -0.014 | 0.2062 | No |
| 121 | IGF1 | NA | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 9670 | -0.039 | 0.1967 | No |
| 122 | ENTPD5 | NA | ENTPD5 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 5 | 9836 | -0.056 | 0.1877 | No |
| 123 | LONP1 | NA | 9846 | -0.058 | 0.1874 | No | ||
| 124 | ADH7 | NA | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 10170 | -0.086 | 0.1696 | No |
| 125 | BCAT1 | NA | BCAT1 Entrez, Source | branched chain aminotransferase 1, cytosolic | 10271 | -0.095 | 0.1643 | No |
| 126 | CDO1 | NA | CDO1 Entrez, Source | cysteine dioxygenase, type I | 10440 | -0.116 | 0.1554 | No |
| 127 | MARCH6 | NA | MARCH6 Entrez, Source | membrane-associated ring finger (C3HC4) 6 | 10722 | -0.157 | 0.1402 | No |
| 128 | SHMT2 | NA | SHMT2 Entrez, Source | serine hydroxymethyltransferase 2 (mitochondrial) | 10957 | -0.192 | 0.1278 | No |
| 129 | ARG1 | NA | ARG1 Entrez, Source | arginase, liver | 11050 | -0.206 | 0.1235 | No |
| 130 | TMEM97 | NA | TMEM97 Entrez, Source | transmembrane protein 97 | 11146 | -0.219 | 0.1190 | No |
| 131 | GSS | NA | GSS Entrez, Source | glutathione synthetase | 11346 | -0.246 | 0.1088 | No |
| 132 | TMBIM6 | NA | 11380 | -0.251 | 0.1080 | No | ||
| 133 | TAT | NA | TAT Entrez, Source | tyrosine aminotransferase | 11480 | -0.268 | 0.1035 | No |
| 134 | CRP | NA | CRP Entrez, Source | C-reactive protein, pentraxin-related | 11506 | -0.273 | 0.1032 | No |
| 135 | ACOX2 | NA | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 11542 | -0.277 | 0.1024 | No |
| 136 | ACP1 | NA | ACP1 Entrez, Source | acid phosphatase 1, soluble | 11731 | -0.301 | 0.0930 | No |
| 137 | CCL25 | NA | CCL25 Entrez, Source | chemokine (C-C motif) ligand 25 | 11922 | -0.329 | 0.0837 | No |
| 138 | ECH1 | NA | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 12276 | -0.380 | 0.0654 | No |
| 139 | MTHFD1 | NA | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 12294 | -0.384 | 0.0660 | No |
| 140 | NMT1 | NA | NMT1 Entrez, Source | N-myristoyltransferase 1 | 12344 | -0.391 | 0.0648 | No |
| 141 | ARG2 | NA | ARG2 Entrez, Source | arginase, type II | 12609 | -0.417 | 0.0517 | No |
| 142 | IRF8 | NA | IRF8 Entrez, Source | interferon regulatory factor 8 | 12681 | -0.431 | 0.0494 | No |
| 143 | UPB1 | NA | UPB1 Entrez, Source | ureidopropionase, beta | 12723 | -0.438 | 0.0489 | No |
| 144 | CAT | NA | CAT Entrez, Source | catalase | 12749 | -0.444 | 0.0493 | No |
| 145 | RBP4 | NA | RBP4 Entrez, Source | retinol binding protein 4, plasma | 12809 | -0.445 | 0.0478 | No |
| 146 | CYP17A1 | NA | CYP17A1 Entrez, Source | cytochrome P450, family 17, subfamily A, polypeptide 1 | 12857 | -0.445 | 0.0470 | No |
| 147 | HRG | NA | HRG Entrez, Source | histidine-rich glycoprotein | 12898 | -0.451 | 0.0466 | No |
| 148 | PROS1 | NA | PROS1 Entrez, Source | protein S (alpha) | 13016 | -0.458 | 0.0419 | No |
| 149 | TYR | NA | TYR Entrez, Source | tyrosinase (oculocutaneous albinism IA) | 13171 | -0.482 | 0.0352 | No |
| 150 | MBL2 | NA | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 13245 | -0.495 | 0.0331 | No |
| 151 | GCH1 | NA | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 13276 | -0.501 | 0.0334 | No |
| 152 | CYP2C18 | NA | CYP2C18 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 18 | 13300 | -0.503 | 0.0342 | No |
| 153 | BPHL | NA | BPHL Entrez, Source | biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen) | 13328 | -0.507 | 0.0347 | No |
| 154 | LEAP2 | NA | LEAP2 Entrez, Source | liver expressed antimicrobial peptide 2 | 13487 | -0.533 | 0.0280 | No |
| 155 | SLC35B1 | NA | SLC35B1 Entrez, Source | solute carrier family 35, member B1 | 13601 | -0.558 | 0.0239 | No |
| 156 | RETSAT | NA | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 13613 | -0.561 | 0.0256 | No |
| 157 | ESR1 | NA | ESR1 Entrez, Source | estrogen receptor 1 | 13783 | -0.591 | 0.0185 | No |
| 158 | KARS | NA | KARS Entrez, Source | lysyl-tRNA synthetase | 13812 | -0.598 | 0.0194 | No |
| 159 | ALDH9A1 | NA | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 14538 | -0.763 | -0.0183 | No |
| 160 | HES6 | NA | HES6 Entrez, Source | hairy and enhancer of split 6 (Drosophila) | 14694 | -0.801 | -0.0237 | No |
| 161 | SERPINA6 | NA | SERPINA6 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | 14870 | -0.839 | -0.0302 | No |
| 162 | ASL | NA | ASL Entrez, Source | argininosuccinate lyase | 14902 | -0.843 | -0.0285 | No |
| 163 | GART | NA | GART Entrez, Source | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | 14946 | -0.854 | -0.0274 | No |
| 164 | ARPP19 | NA | 15004 | -0.869 | -0.0271 | No | ||
| 165 | AP4B1 | NA | AP4B1 Entrez, Source | adaptor-related protein complex 4, beta 1 subunit | 15042 | -0.878 | -0.0256 | No |
| 166 | PTS | NA | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 15057 | -0.882 | -0.0228 | No |
| 167 | SSR3 | NA | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 15062 | -0.883 | -0.0194 | No |
| 168 | XDH | NA | XDH Entrez, Source | xanthine dehydrogenase | 15077 | -0.887 | -0.0166 | No |
| 169 | AHCY | NA | AHCY Entrez, Source | S-adenosylhomocysteine hydrolase | 15150 | -0.902 | -0.0169 | No |
| 170 | PYCR1 | NA | PYCR1 Entrez, Source | pyrroline-5-carboxylate reductase 1 | 15311 | -0.944 | -0.0221 | No |
| 171 | ITIH1 | NA | ITIH1 Entrez, Source | inter-alpha (globulin) inhibitor H1 | 15404 | -0.969 | -0.0233 | No |
| 172 | GSTO1 | NA | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 15522 | -1.003 | -0.0258 | No |
| 173 | PAPSS2 | NA | PAPSS2 Entrez, Source | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 15536 | -1.007 | -0.0224 | No |
| 174 | HPRT1 | NA | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 15561 | -1.015 | -0.0197 | No |
| 175 | FBLN1 | NA | FBLN1 Entrez, Source | fibulin 1 | 16008 | -1.179 | -0.0399 | No |
| 176 | SLC6A12 | NA | SLC6A12 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 16078 | -1.205 | -0.0389 | No |
| 177 | DCXR | NA | DCXR Entrez, Source | dicarbonyl/L-xylulose reductase | 16185 | -1.251 | -0.0398 | No |
| 178 | AOX1 | NA | AOX1 Entrez, Source | aldehyde oxidase 1 | 16202 | -1.260 | -0.0355 | No |
| 179 | CYB5A | NA | CYB5A Entrez, Source | cytochrome b5 type A (microsomal) | 16238 | -1.277 | -0.0323 | No |
| 180 | PGRMC1 | NA | PGRMC1 Entrez, Source | progesterone receptor membrane component 1 | 16272 | -1.293 | -0.0289 | No |
| 181 | LCAT | NA | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 16334 | -1.325 | -0.0269 | No |
| 182 | GNMT | NA | GNMT Entrez, Source | glycine N-methyltransferase | 16363 | -1.341 | -0.0230 | No |
| 183 | MCCC2 | NA | MCCC2 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 16481 | -1.403 | -0.0239 | No |
| 184 | ETS2 | NA | ETS2 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 16498 | -1.412 | -0.0190 | No |
| 185 | HACL1 | NA | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 16743 | -1.560 | -0.0264 | No |
| 186 | CNDP2 | NA | CNDP2 Entrez, Source | CNDP dipeptidase 2 (metallopeptidase M20 family) | 16852 | -1.646 | -0.0258 | No |
| 187 | SLC22A1 | NA | SLC22A1 Entrez, Source | solute carrier family 22 (organic cation transporter), member 1 | 16966 | -1.738 | -0.0250 | No |
| 188 | GSTM4 | NA | GSTM4 Entrez, Source | glutathione S-transferase M4 | 17120 | -1.897 | -0.0259 | No |
| 189 | COMT | NA | COMT Entrez, Source | catechol-O-methyltransferase | 17121 | -1.899 | -0.0182 | No |
| 190 | PEMT | NA | PEMT Entrez, Source | phosphatidylethanolamine N-methyltransferase | 17239 | -2.065 | -0.0163 | No |
| 191 | SLC46A3 | NA | 17343 | -2.238 | -0.0130 | No | ||
| 192 | VNN1 | NA | VNN1 Entrez, Source | vanin 1 | 17510 | -2.530 | -0.0120 | No |
| 193 | TMEM176B | NA | TMEM176B Entrez, Source | transmembrane protein 176B | 17556 | -2.601 | -0.0040 | No |
| 194 | HSD11B1 | NA | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 17669 | -2.989 | 0.0019 | No |
| 195 | MPP2 | NA | MPP2 Entrez, Source | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 17826 | -3.727 | 0.0083 | No |
