Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | -0.53051305 |
| Normalized Enrichment Score (NES) | -1.9196668 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.2500004E-4 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SRM | NA | SRM Entrez, Source | spermidine synthase | 1221 | 2.023 | -0.0148 | No |
| 2 | BYSL | NA | BYSL Entrez, Source | bystin-like | 4038 | 0.753 | -0.1521 | No |
| 3 | IPO4 | NA | IPO4 Entrez, Source | importin 4 | 4050 | 0.751 | -0.1329 | No |
| 4 | SLC19A1 | NA | SLC19A1 Entrez, Source | solute carrier family 19 (folate transporter), member 1 | 5910 | 0.428 | -0.2254 | No |
| 5 | DUSP2 | NA | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 5929 | 0.424 | -0.2152 | No |
| 6 | HSPD1 | NA | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 6826 | 0.318 | -0.2569 | No |
| 7 | WDR74 | NA | WDR74 Entrez, Source | WD repeat domain 74 | 6980 | 0.293 | -0.2577 | No |
| 8 | NOP2 | NA | 7395 | 0.226 | -0.2748 | No | ||
| 9 | TCOF1 | NA | TCOF1 Entrez, Source | Treacher Collins-Franceschetti syndrome 1 | 7440 | 0.220 | -0.2715 | No |
| 10 | IMP4 | NA | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 7735 | 0.179 | -0.2832 | No |
| 11 | NOP16 | NA | 7860 | 0.164 | -0.2857 | No | ||
| 12 | HSPE1 | NA | HSPE1 Entrez, Source | heat shock 10kDa protein 1 (chaperonin 10) | 8626 | 0.063 | -0.3268 | No |
| 13 | PPAN | NA | PPAN Entrez, Source | peter pan homolog (Drosophila) | 8920 | 0.025 | -0.3425 | No |
| 14 | FARSA | NA | 8936 | 0.023 | -0.3427 | No | ||
| 15 | MAP3K6 | NA | MAP3K6 Entrez, Source | mitogen-activated protein kinase kinase kinase 6 | 9037 | 0.014 | -0.3479 | No |
| 16 | RABEPK | NA | RABEPK Entrez, Source | Rab9 effector protein with kelch motifs | 9137 | 0.006 | -0.3533 | No |
| 17 | NOC4L | NA | NOC4L Entrez, Source | nucleolar complex associated 4 homolog (S. cerevisiae) | 9534 | -0.020 | -0.3749 | No |
| 18 | UTP20 | NA | UTP20 Entrez, Source | UTP20, small subunit (SSU) processome component, homolog (yeast) | 9593 | -0.029 | -0.3773 | No |
| 19 | MRTO4 | NA | 9713 | -0.045 | -0.3828 | No | ||
| 20 | NOP56 | NA | 10538 | -0.129 | -0.4254 | No | ||
| 21 | SLC29A2 | NA | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 10680 | -0.151 | -0.4293 | No |
| 22 | AIMP2 | NA | 10839 | -0.176 | -0.4334 | No | ||
| 23 | TMEM97 | NA | TMEM97 Entrez, Source | transmembrane protein 97 | 11146 | -0.219 | -0.4448 | No |
| 24 | NPM1 | NA | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 11767 | -0.307 | -0.4713 | No |
| 25 | UNG | NA | UNG Entrez, Source | uracil-DNA glycosylase | 11768 | -0.307 | -0.4632 | No |
| 26 | SUPV3L1 | NA | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 12080 | -0.351 | -0.4713 | No |
| 27 | NDUFAF4 | NA | 12149 | -0.361 | -0.4656 | No | ||
| 28 | GRWD1 | NA | GRWD1 Entrez, Source | glutamate-rich WD repeat containing 1 | 12596 | -0.415 | -0.4795 | No |
| 29 | LAS1L | NA | LAS1L Entrez, Source | LAS1-like (S. cerevisiae) | 13511 | -0.538 | -0.5163 | Yes |
| 30 | PA2G4 | NA | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 13512 | -0.539 | -0.5021 | Yes |
| 31 | PES1 | NA | PES1 Entrez, Source | pescadillo homolog 1, containing BRCT domain (zebrafish) | 13551 | -0.546 | -0.4898 | Yes |
| 32 | PHB | NA | PHB Entrez, Source | prohibitin | 13936 | -0.621 | -0.4949 | Yes |
| 33 | CDK4 | NA | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 13941 | -0.622 | -0.4787 | Yes |
| 34 | TBRG4 | NA | TBRG4 Entrez, Source | transforming growth factor beta regulator 4 | 14028 | -0.642 | -0.4665 | Yes |
| 35 | PLK1 | NA | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 14126 | -0.664 | -0.4544 | Yes |
| 36 | RCL1 | NA | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 14132 | -0.665 | -0.4372 | Yes |
| 37 | RRP12 | NA | 14178 | -0.677 | -0.4218 | Yes | ||
| 38 | MYBBP1A | NA | MYBBP1A Entrez, Source | MYB binding protein (P160) 1a | 14254 | -0.691 | -0.4078 | Yes |
| 39 | DDX18 | NA | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 14334 | -0.709 | -0.3935 | Yes |
| 40 | PUS1 | NA | PUS1 Entrez, Source | pseudouridylate synthase 1 | 14710 | -0.804 | -0.3932 | Yes |
| 41 | WDR43 | NA | WDR43 Entrez, Source | WD repeat domain 43 | 14737 | -0.811 | -0.3733 | Yes |
| 42 | PPRC1 | NA | PPRC1 Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator-related 1 | 14808 | -0.828 | -0.3554 | Yes |
| 43 | MCM4 | NA | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 14975 | -0.861 | -0.3419 | Yes |
| 44 | MYC | NA | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 15055 | -0.881 | -0.3231 | Yes |
| 45 | SORD | NA | SORD Entrez, Source | sorbitol dehydrogenase | 15152 | -0.903 | -0.3047 | Yes |
| 46 | EXOSC5 | NA | EXOSC5 Entrez, Source | exosome component 5 | 15220 | -0.920 | -0.2841 | Yes |
| 47 | RRP9 | NA | 15395 | -0.968 | -0.2683 | Yes | ||
| 48 | MCM5 | NA | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 15464 | -0.988 | -0.2461 | Yes |
| 49 | PRMT3 | NA | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 15509 | -1.001 | -0.2221 | Yes |
| 50 | PLK4 | NA | PLK4 Entrez, Source | polo-like kinase 4 (Drosophila) | 15631 | -1.039 | -0.2015 | Yes |
| 51 | NIP7 | NA | NIP7 Entrez, Source | nuclear import 7 homolog (S. cerevisiae) | 15751 | -1.079 | -0.1797 | Yes |
| 52 | CBX3 | NA | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 15892 | -1.133 | -0.1576 | Yes |
| 53 | GNL3 | NA | GNL3 Entrez, Source | guanine nucleotide binding protein-like 3 (nucleolar) | 16070 | -1.203 | -0.1358 | Yes |
| 54 | TFB2M | NA | TFB2M Entrez, Source | transcription factor B2, mitochondrial | 16325 | -1.320 | -0.1151 | Yes |
| 55 | DCTPP1 | NA | 16757 | -1.567 | -0.0979 | Yes | ||
| 56 | NOLC1 | NA | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 17035 | -1.802 | -0.0658 | Yes |
| 57 | HK2 | NA | HK2 Entrez, Source | hexokinase 2 | 17222 | -2.037 | -0.0225 | Yes |
| 58 | MPHOSPH10 | NA | MPHOSPH10 Entrez, Source | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) | 17471 | -2.442 | 0.0281 | Yes |
