Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | HALLMARK_ANGIOGENESIS |
| Enrichment Score (ES) | 0.45771506 |
| Normalized Enrichment Score (NES) | 1.3871619 |
| Nominal p-value | 0.07097792 |
| FDR q-value | 0.046166614 |
| FWER p-Value | 0.617 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LPL | NA | LPL Entrez, Source | lipoprotein lipase | 51 | 4.717 | 0.0745 | Yes |
| 2 | S100A4 | NA | S100A4 Entrez, Source | S100 calcium binding protein A4 | 79 | 4.577 | 0.1481 | Yes |
| 3 | LUM | NA | LUM Entrez, Source | lumican | 356 | 3.561 | 0.1912 | Yes |
| 4 | THBD | NA | THBD Entrez, Source | thrombomodulin | 371 | 3.510 | 0.2480 | Yes |
| 5 | JAG2 | NA | JAG2 Entrez, Source | jagged 2 | 400 | 3.433 | 0.3027 | Yes |
| 6 | JAG1 | NA | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 495 | 3.207 | 0.3501 | Yes |
| 7 | TNFRSF21 | NA | TNFRSF21 Entrez, Source | tumor necrosis factor receptor superfamily, member 21 | 539 | 3.100 | 0.3986 | Yes |
| 8 | FGFR1 | NA | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 688 | 2.742 | 0.4353 | Yes |
| 9 | VEGFA | NA | 1501 | 1.765 | 0.4190 | Yes | ||
| 10 | LRPAP1 | NA | LRPAP1 Entrez, Source | low density lipoprotein receptor-related protein associated protein 1 | 1763 | 1.550 | 0.4299 | Yes |
| 11 | PF4 | NA | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 2166 | 1.324 | 0.4292 | Yes |
| 12 | NRP1 | NA | NRP1 Entrez, Source | neuropilin 1 | 2191 | 1.309 | 0.4493 | Yes |
| 13 | SPP1 | NA | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 2399 | 1.215 | 0.4577 | Yes |
| 14 | POSTN | NA | POSTN Entrez, Source | periostin, osteoblast specific factor | 3038 | 0.978 | 0.4382 | No |
| 15 | TIMP1 | NA | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 3284 | 0.917 | 0.4396 | No |
| 16 | APOH | NA | APOH Entrez, Source | apolipoprotein H (beta-2-glycoprotein I) | 3536 | 0.846 | 0.4395 | No |
| 17 | STC1 | NA | STC1 Entrez, Source | stanniocalcin 1 | 3795 | 0.811 | 0.4384 | No |
| 18 | ITGAV | NA | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 3832 | 0.802 | 0.4496 | No |
| 19 | FSTL1 | NA | FSTL1 Entrez, Source | follistatin-like 1 | 4350 | 0.689 | 0.4320 | No |
| 20 | KCNJ8 | NA | KCNJ8 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 8 | 4704 | 0.616 | 0.4225 | No |
| 21 | VTN | NA | VTN Entrez, Source | vitronectin | 5658 | 0.451 | 0.3767 | No |
| 22 | COL3A1 | NA | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 6922 | 0.302 | 0.3113 | No |
| 23 | PGLYRP1 | NA | PGLYRP1 Entrez, Source | peptidoglycan recognition protein 1 | 7359 | 0.233 | 0.2908 | No |
| 24 | VAV2 | NA | VAV2 Entrez, Source | vav 2 oncogene | 8212 | 0.118 | 0.2453 | No |
| 25 | PRG2 | NA | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 11325 | -0.242 | 0.0758 | No |
| 26 | MSX1 | NA | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 11674 | -0.292 | 0.0611 | No |
| 27 | OLR1 | NA | OLR1 Entrez, Source | oxidised low density lipoprotein (lectin-like) receptor 1 | 12060 | -0.347 | 0.0454 | No |
| 28 | PTK2 | NA | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 12873 | -0.447 | 0.0075 | No |
| 29 | CXCL6 | NA | CXCL6 Entrez, Source | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 12913 | -0.451 | 0.0127 | No |
| 30 | APP | NA | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 15153 | -0.903 | -0.0973 | No |
| 31 | COL5A2 | NA | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 15860 | -1.120 | -0.1183 | No |
| 32 | CCND2 | NA | CCND2 Entrez, Source | cyclin D2 | 16061 | -1.200 | -0.1098 | No |
| 33 | PDGFA | NA | PDGFA Entrez, Source | platelet-derived growth factor alpha polypeptide | 17541 | -2.598 | -0.1496 | No |
| 34 | SERPINA5 | NA | SERPINA5 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 17565 | -2.622 | -0.1079 | No |
| 35 | SLCO2A1 | NA | SLCO2A1 Entrez, Source | solute carrier organic anion transporter family, member 2A1 | 17738 | -3.303 | -0.0633 | No |
| 36 | VCAN | NA | 17935 | -4.655 | 0.0022 | No |
