Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_SPLICEOSOME |
| Enrichment Score (ES) | -0.41255128 |
| Normalized Enrichment Score (NES) | -1.6506765 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.10167619 |
| FWER p-Value | 0.255 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HSPA1A | NA | HSPA1A Entrez, Source | heat shock 70kDa protein 1A | 1411 | 1.945 | -0.0528 | No |
| 2 | LSM2 | NA | LSM2 Entrez, Source | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 1468 | 1.899 | -0.0303 | No |
| 3 | THOC3 | NA | THOC3 Entrez, Source | THO complex 3 | 2262 | 1.425 | -0.0555 | No |
| 4 | PQBP1 | NA | PQBP1 Entrez, Source | polyglutamine binding protein 1 | 2579 | 1.288 | -0.0559 | No |
| 5 | HSPA1B | NA | HSPA1B Entrez, Source | heat shock 70kDa protein 1B | 2713 | 1.240 | -0.0466 | No |
| 6 | DHX16 | NA | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 3381 | 1.033 | -0.0700 | No |
| 7 | SLU7 | NA | SLU7 Entrez, Source | - | 4178 | 0.822 | -0.1035 | No |
| 8 | TRA2B | NA | 4183 | 0.821 | -0.0927 | No | ||
| 9 | PRPF40A | NA | PRPF40A Entrez, Source | PRP40 pre-mRNA processing factor 40 homolog A (yeast) | 4247 | 0.804 | -0.0853 | No |
| 10 | SF3B1 | NA | SF3B1 Entrez, Source | splicing factor 3b, subunit 1, 155kDa | 4294 | 0.794 | -0.0772 | No |
| 11 | SNRPC | NA | SNRPC Entrez, Source | small nuclear ribonucleoprotein polypeptide C | 4467 | 0.755 | -0.0767 | No |
| 12 | HSPA1L | NA | HSPA1L Entrez, Source | heat shock 70kDa protein 1-like | 4638 | 0.716 | -0.0765 | No |
| 13 | BCAS2 | NA | BCAS2 Entrez, Source | breast carcinoma amplified sequence 2 | 4756 | 0.693 | -0.0737 | No |
| 14 | PPIL1 | NA | PPIL1 Entrez, Source | peptidylprolyl isomerase (cyclophilin)-like 1 | 5085 | 0.626 | -0.0837 | No |
| 15 | RBM22 | NA | RBM22 Entrez, Source | RNA binding motif protein 22 | 5144 | 0.615 | -0.0786 | No |
| 16 | HSPA8 | NA | HSPA8 Entrez, Source | heat shock 70kDa protein 8 | 5216 | 0.601 | -0.0745 | No |
| 17 | ZMAT2 | NA | ZMAT2 Entrez, Source | zinc finger, matrin type 2 | 5358 | 0.575 | -0.0746 | No |
| 18 | CRNKL1 | NA | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 5602 | 0.534 | -0.0811 | No |
| 19 | SNRNP40 | NA | 5659 | 0.524 | -0.0771 | No | ||
| 20 | DHX15 | NA | DHX15 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 15 | 6257 | 0.420 | -0.1049 | No |
| 21 | PLRG1 | NA | PLRG1 Entrez, Source | pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) | 6829 | 0.339 | -0.1323 | No |
| 22 | SNRPB | NA | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 6855 | 0.335 | -0.1292 | No |
| 23 | PRPF3 | NA | PRPF3 Entrez, Source | PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) | 7166 | 0.292 | -0.1426 | No |
| 24 | SRSF1 | NA | 7427 | 0.259 | -0.1537 | No | ||
| 25 | TCERG1 | NA | TCERG1 Entrez, Source | transcription elongation regulator 1 | 7475 | 0.256 | -0.1529 | No |
| 26 | SNRPB2 | NA | SNRPB2 Entrez, Source | small nuclear ribonucleoprotein polypeptide B'' | 7949 | 0.209 | -0.1765 | No |
| 27 | HNRNPA3 | NA | 8012 | 0.201 | -0.1773 | No | ||
| 28 | BUD31 | NA | BUD31 Entrez, Source | BUD31 homolog (yeast) | 8088 | 0.191 | -0.1789 | No |
| 29 | SRSF8 | NA | 8133 | 0.185 | -0.1789 | No | ||
| 30 | CWC15 | NA | 8333 | 0.167 | -0.1878 | No | ||
| 31 | ACIN1 | NA | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 8399 | 0.162 | -0.1893 | No |
| 32 | PPIE | NA | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 8525 | 0.150 | -0.1942 | No |
| 33 | WBP11 | NA | WBP11 Entrez, Source | WW domain binding protein 11 | 8760 | 0.125 | -0.2057 | No |
| 34 | DDX46 | NA | DDX46 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 9056 | 0.093 | -0.2209 | No |
| 35 | U2AF2 | NA | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 9251 | 0.075 | -0.2308 | No |
| 36 | TXNL4A | NA | TXNL4A Entrez, Source | thioredoxin-like 4A | 9479 | 0.055 | -0.2427 | No |
| 37 | PRPF18 | NA | PRPF18 Entrez, Source | PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae) | 9537 | 0.047 | -0.2453 | No |
| 38 | DDX23 | NA | DDX23 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | 9593 | 0.042 | -0.2478 | No |
| 39 | SRSF10 | NA | 9704 | 0.025 | -0.2536 | No | ||
| 40 | CDC5L | NA | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 9778 | 0.014 | -0.2575 | No |
| 41 | DDX39B | NA | 9846 | 0.004 | -0.2612 | No | ||
| 42 | RBM17 | NA | RBM17 Entrez, Source | RNA binding motif protein 17 | 10219 | -0.007 | -0.2820 | No |
| 43 | PRPF4 | NA | PRPF4 Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog (yeast) | 10244 | -0.011 | -0.2832 | No |
| 44 | DDX42 | NA | DDX42 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 | 10262 | -0.012 | -0.2839 | No |
| 45 | MAGOHB | NA | 10300 | -0.014 | -0.2858 | No | ||
| 46 | SYF2 | NA | SYF2 Entrez, Source | SYF2 homolog, RNA splicing factor (S. cerevisiae) | 10321 | -0.017 | -0.2867 | No |
| 47 | SMNDC1 | NA | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 10512 | -0.032 | -0.2969 | No |
| 48 | CTNNBL1 | NA | CTNNBL1 Entrez, Source | catenin, beta like 1 | 10522 | -0.034 | -0.2970 | No |
| 49 | NCBP2 | NA | NCBP2 Entrez, Source | nuclear cap binding protein subunit 2, 20kDa | 10803 | -0.059 | -0.3118 | No |
| 50 | PRPF31 | NA | PRPF31 Entrez, Source | PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) | 10817 | -0.060 | -0.3118 | No |
| 51 | DHX38 | NA | DHX38 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | 10937 | -0.075 | -0.3174 | No |
| 52 | SNRPA | NA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 11451 | -0.128 | -0.3444 | No |
| 53 | HSPA6 | NA | HSPA6 Entrez, Source | heat shock 70kDa protein 6 (HSP70B') | 11611 | -0.145 | -0.3514 | No |
| 54 | SNW1 | NA | SNW1 Entrez, Source | SNW domain containing 1 | 11688 | -0.153 | -0.3536 | No |
| 55 | SRSF4 | NA | 11773 | -0.165 | -0.3560 | No | ||
| 56 | DDX5 | NA | DDX5 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 12008 | -0.191 | -0.3666 | No |
| 57 | SF3B2 | NA | SF3B2 Entrez, Source | splicing factor 3b, subunit 2, 145kDa | 12291 | -0.225 | -0.3793 | No |
| 58 | DHX8 | NA | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 12322 | -0.230 | -0.3779 | No |
| 59 | SART1 | NA | SART1 Entrez, Source | squamous cell carcinoma antigen recognised by T cells | 12895 | -0.300 | -0.4059 | No |
| 60 | PRPF38B | NA | PRPF38B Entrez, Source | PRP38 pre-mRNA processing factor 38 (yeast) domain containing B | 13015 | -0.321 | -0.4082 | Yes |
| 61 | RBM8A | NA | RBM8A Entrez, Source | RNA binding motif protein 8A | 13066 | -0.328 | -0.4066 | Yes |
| 62 | XAB2 | NA | XAB2 Entrez, Source | XPA binding protein 2 | 13072 | -0.329 | -0.4024 | Yes |
| 63 | SRSF5 | NA | 13087 | -0.332 | -0.3987 | Yes | ||
| 64 | SNRNP70 | NA | 13106 | -0.335 | -0.3952 | Yes | ||
| 65 | EIF4A3 | NA | 13149 | -0.340 | -0.3930 | Yes | ||
| 66 | SRSF6 | NA | 13182 | -0.346 | -0.3901 | Yes | ||
| 67 | RBM25 | NA | RBM25 Entrez, Source | RNA binding motif protein 25 | 13321 | -0.370 | -0.3929 | Yes |
| 68 | PUF60 | NA | 13463 | -0.392 | -0.3955 | Yes | ||
| 69 | HNRNPC | NA | 13512 | -0.402 | -0.3927 | Yes | ||
| 70 | SF3B4 | NA | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 13557 | -0.409 | -0.3897 | Yes |
| 71 | CHERP | NA | CHERP Entrez, Source | calcium homeostasis endoplasmic reticulum protein | 13560 | -0.409 | -0.3843 | Yes |
| 72 | NCBP1 | NA | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 13584 | -0.413 | -0.3800 | Yes |
| 73 | HNRNPU | NA | 13685 | -0.431 | -0.3798 | Yes | ||
| 74 | PRPF6 | NA | PRPF6 Entrez, Source | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 13715 | -0.439 | -0.3755 | Yes |
| 75 | SRSF2 | NA | 13723 | -0.441 | -0.3700 | Yes | ||
| 76 | SNRNP200 | NA | 13814 | -0.455 | -0.3689 | Yes | ||
| 77 | SNRPD2 | NA | SNRPD2 Entrez, Source | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | 13841 | -0.461 | -0.3641 | Yes |
| 78 | PRPF38A | NA | PRPF38A Entrez, Source | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A | 13886 | -0.468 | -0.3603 | Yes |
| 79 | SF3A2 | NA | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 13998 | -0.490 | -0.3599 | Yes |
| 80 | RBMX | NA | RBMX Entrez, Source | RNA binding motif protein, X-linked | 14032 | -0.496 | -0.3550 | Yes |
| 81 | SF3B5 | NA | SF3B5 Entrez, Source | splicing factor 3b, subunit 5, 10kDa | 14033 | -0.496 | -0.3483 | Yes |
| 82 | LSM4 | NA | LSM4 Entrez, Source | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 14166 | -0.524 | -0.3487 | Yes |
| 83 | HNRNPK | NA | 14278 | -0.547 | -0.3475 | Yes | ||
| 84 | PRPF40B | NA | PRPF40B Entrez, Source | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | 14315 | -0.554 | -0.3421 | Yes |
| 85 | PHF5A | NA | PHF5A Entrez, Source | PHD finger protein 5A | 14336 | -0.559 | -0.3356 | Yes |
| 86 | AQR | NA | AQR Entrez, Source | aquarius homolog (mouse) | 14378 | -0.568 | -0.3303 | Yes |
| 87 | EFTUD2 | NA | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 14422 | -0.577 | -0.3249 | Yes |
| 88 | PRPF8 | NA | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 14541 | -0.602 | -0.3234 | Yes |
| 89 | SNRPD1 | NA | SNRPD1 Entrez, Source | small nuclear ribonucleoprotein D1 polypeptide 16kDa | 14580 | -0.613 | -0.3173 | Yes |
| 90 | TRA2A | NA | TRA2A Entrez, Source | - | 14596 | -0.617 | -0.3098 | Yes |
| 91 | SF3A1 | NA | SF3A1 Entrez, Source | splicing factor 3a, subunit 1, 120kDa | 14675 | -0.637 | -0.3056 | Yes |
| 92 | SNRPD3 | NA | SNRPD3 Entrez, Source | small nuclear ribonucleoprotein D3 polypeptide 18kDa | 14717 | -0.647 | -0.2991 | Yes |
| 93 | SRSF7 | NA | 14726 | -0.652 | -0.2908 | Yes | ||
| 94 | SNRPF | NA | SNRPF Entrez, Source | small nuclear ribonucleoprotein polypeptide F | 14756 | -0.659 | -0.2835 | Yes |
| 95 | THOC1 | NA | THOC1 Entrez, Source | THO complex 1 | 14832 | -0.678 | -0.2786 | Yes |
| 96 | HNRNPM | NA | 14866 | -0.686 | -0.2712 | Yes | ||
| 97 | LSM5 | NA | LSM5 Entrez, Source | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 14957 | -0.709 | -0.2667 | Yes |
| 98 | SF3B3 | NA | SF3B3 Entrez, Source | splicing factor 3b, subunit 3, 130kDa | 15105 | -0.747 | -0.2648 | Yes |
| 99 | CCDC12 | NA | CCDC12 Entrez, Source | coiled-coil domain containing 12 | 15161 | -0.763 | -0.2576 | Yes |
| 100 | U2AF1 | NA | U2AF1 Entrez, Source | U2 small nuclear RNA auxiliary factor 1 | 15624 | -0.904 | -0.2713 | Yes |
| 101 | SRSF3 | NA | 15652 | -0.910 | -0.2606 | Yes | ||
| 102 | LSM7 | NA | LSM7 Entrez, Source | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 15694 | -0.928 | -0.2504 | Yes |
| 103 | HSPA2 | NA | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 15823 | -0.979 | -0.2443 | Yes |
| 104 | PRPF19 | NA | PRPF19 Entrez, Source | PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) | 15854 | -0.988 | -0.2327 | Yes |
| 105 | LSM6 | NA | LSM6 Entrez, Source | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 15863 | -0.992 | -0.2198 | Yes |
| 106 | SNRPE | NA | SNRPE Entrez, Source | small nuclear ribonucleoprotein polypeptide E | 15878 | -0.999 | -0.2071 | Yes |
| 107 | LSM3 | NA | LSM3 Entrez, Source | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 16170 | -1.122 | -0.2082 | Yes |
| 108 | PPIH | NA | PPIH Entrez, Source | peptidylprolyl isomerase H (cyclophilin H) | 16174 | -1.126 | -0.1932 | Yes |
| 109 | HNRNPA1 | NA | 16182 | -1.129 | -0.1784 | Yes | ||
| 110 | USP39 | NA | USP39 Entrez, Source | ubiquitin specific peptidase 39 | 16192 | -1.138 | -0.1636 | Yes |
| 111 | SNRPA1 | NA | SNRPA1 Entrez, Source | small nuclear ribonucleoprotein polypeptide A' | 16292 | -1.190 | -0.1531 | Yes |
| 112 | HNRNPA1L2 | NA | 16326 | -1.205 | -0.1387 | Yes | ||
| 113 | MAGOH | NA | MAGOH Entrez, Source | mago-nashi homolog, proliferation-associated (Drosophila) | 16366 | -1.227 | -0.1243 | Yes |
| 114 | NAA38 | NA | 16474 | -1.281 | -0.1130 | Yes | ||
| 115 | SF3A3 | NA | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 16509 | -1.308 | -0.0973 | Yes |
| 116 | CDC40 | NA | CDC40 Entrez, Source | cell division cycle 40 homolog (S. cerevisiae) | 16618 | -1.377 | -0.0848 | Yes |
| 117 | ISY1 | NA | 16727 | -1.452 | -0.0713 | Yes | ||
| 118 | SNRNP27 | NA | 16776 | -1.485 | -0.0539 | Yes | ||
| 119 | THOC2 | NA | THOC2 Entrez, Source | THO complex 2 | 16784 | -1.490 | -0.0342 | Yes |
| 120 | U2SURP | NA | 16801 | -1.508 | -0.0148 | Yes | ||
| 121 | PCBP1 | NA | PCBP1 Entrez, Source | poly(rC) binding protein 1 | 17068 | -1.756 | -0.0060 | Yes |
| 122 | SRSF9 | NA | 17108 | -1.795 | 0.0160 | Yes | ||
| 123 | SNRPG | NA | SNRPG Entrez, Source | small nuclear ribonucleoprotein polypeptide G | 17505 | -2.432 | 0.0266 | Yes |
